9,486
Views
140
CrossRef citations to date
0
Altmetric
Research Article

Nanoemulsion gel-based topical delivery of an antifungal drug: in vitro activity and in vivo evaluation

, , , , , & show all
Pages 642-657 | Received 29 Apr 2014, Accepted 06 Jun 2014, Published online: 11 Jul 2014

References

  • Attwood D, Mallon D, Taylor CJ. (1992). Phase studies on oil in water microemulsions. Int J Pharm 8:R5–8
  • Azeem A, Rizwan M, Ahmad FJ, et al. (2009). Nanoemulsion components screening and selection: a technical note. AAPS PharmSci Tech 10:69–76
  • Borgia SL, Regehly M, Sivaramakrishnan R, et al. (2005). Lipid nanoparticles for skin penetration enhancement-correlation to drug localization within the particle matrix as determined by fluorescence and parelectric spectroscopy. J Contr Rel 110:151–63
  • Bowser PA, White RJ. (1985). Isolation, barrier properties and lipid analysis of stratum compactum, a discrete region of the stratum corneum, Br J Dermatol 112:1–14
  • Carelli V, Di Colo G, Nannipieri E, et al. (1998). Effect of vehicles on yohimbine permeation across excised hairless mouse skin. Pharm Acta Helv 73:127–34
  • Changez M, Varshney M, Chander J, et al. (2006). Effect of the composition of lecithin/ n-propanol/isopropyl myristate/water microemulsions on barrier properties of rat skin for transdermal permeation of tetracaine hydrochloride: in vitro. Colloids Surf B Biointerfaces 50:18–25
  • Chen H, Chang X, Du D, et al. (2006). Podophyllotoxin-loaded solid lipid nanoparticles for epidermal targeting, J Contr Rel 110:296–306
  • Chen-Yu G, Chun-Fen Y, Qui-Lu L, et al. (2012). Development of quercetin-loaded nanostructured lipid carrier formulation for topical delivery. Int J Pharm 430:292–8
  • Chow KT, Chan LW, Heng PWS. (1997). Characterization of spreadability of nonaqueous 334 ethylcell ulose gel matrices using dynamic contact angle. J Pharm Sci 97:3467–82
  • Draize J, Woodard G, Calvery H. (1944). Methods for the study of irritation and toxicity of substances applied topically to the skin and mucous membranes. J Phamacol Exp Ther 82:377–90
  • Dubey V, Mishra D, Dutta T, et al. (2007). Dermal and transdermal delivery of an anti-psoriatic agent via ethanolic liposomes. J Contr Rel 123:148–54
  • Elias PM. (1996). The stratum corneum revisited. J. Dermatol 23:756–8
  • Espuelas MS, Legrand P, Irache JM, et al. (1997). Poly(ε-caprolacton) nanospheres as an alternative way to reduce amphotericin B toxicity. Int J Pharm 158:19–27
  • Formariz TP, Sarmento VHV, Silva-Junior AA, et al. (2006). Doxorubicin biocompatible O/W microemulsion stabilized by mixed surfactant containing soya phosphatidylcholine. Colloids Surf B Biointerfaces 51:54–61
  • Formariz TP, Urban MCC, Silva-Júnior AA, et al. (2005). Microemulsões e fases líquidas cristalinas como sistemas de liberação de fármacos. Braz J Pharm Sci 41:301–13
  • Fukui H, Koike T, Nakagawa T, et al. (2003a). Comparison of LNS-AmB, a novel low-dose formulation of amphotericin B with lipid nano-sphere (LNS®) with commercial lipid-based formulations. Int J Pharm 267:101–12
  • Fukui H, Koike T, Saheki A, et al. (2003b). Evaluation of the efficacy and toxicity of amphotericin B incorporated in lipid nano-sphere (LNS®). Int J Pharm 263:51–60
  • Fukui H, Koike T, Saheki A, et al. (2003c). A novel delivery system for amphotericin B with lipid nano-sphere (LNS®). Int J Pharm 265:37–45
  • Glavas-Dodov M, Fredro-Kumbaradzi E, Goracinova K, et al. (2005). The effects of lyophilization on the stability of liposomes containing 5-FU. Int J Pharm 291:79–86
  • Godwin DA, Michniak BB, Creek KE. (1997). Evaluation of transdermal penetration enhancers using a novel skin alternative. J Pharm Sci 86:1001–5
  • Golden GM, Guzek DB, Harris RR, et al. (1986). Lipid thermotropic transitions in human stratum corneum. J Invest Dermatol 86:255–9
  • Hu FQ, Jiang SP, Du YZ, et al. (2006). Preparation and characteristics of monostearin nanostructured lipid carriers. Int J Pharm 314:83–9
  • Hussain A, Samad A, Nazish I, et al. (2013). Nanocarrier-based topical drug delivery for an antifungal drug. Drug Dev Ind Pharm 40:527–41
  • Hussain A, Samad A, Singh SK, et al. (2014). Enhanced stability and permeation potential of nanoemulsion containing sefsol-218 oil for topical delivery of amphotericin. B Drug Dev Ind Pharm. [Epub ahead of print]
  • Kadimi US, Balasubramanian DR, Ganni UR, et al. (2007). In vitro studies on liposomal amphotericin B obtained by supercritical carbon dioxide –mediated process. Nanomedicine 3:273–80
  • Khurana S. (2013). Nanoemulsion based gel for transdermal delivery of meloxicam: physico-chemical, mechanistic investigation. Life Sci 92:383–92
  • Kleinberg M. (2006). What is the current and future status of conventional amphotericin B? Int J Antimicrob Agents 27S:S12–16
  • Kumar A, Ali M, Pandey BN, et al. (2010). Role of membrane sialic acid and glycophorin protein in thorium induced aggregation and hemolysis of human erythrocytes. Biochimie 92:869–79
  • Lemke A, Kiderlen AF, Kayser O. (2005). Amphotericin B. Appl Microbiol Biotechnol 68:151–62
  • Nahar M, Mishra D, Dubey V, et al. (2008). Development, characterization and toxicity evaluation of amphotericin B-loaded gelatin nanoparticles. Nanomedicine NBM 4:252–61
  • OECD Guidelines, Test Guideline 402. Acute dermal toxicity. Paris: OECD, 1987
  • OECD Guidelines, Test Guideline 410. Repeated dose dermal Toxicity: 21/28-day study. Paris: OECD, 1981
  • Perkins WR, Minchey SR, Boni LT, et al. (1992). Amphotericin B phospholipid interactions responsible for reduced mammalian cell toxicity. Biochim Bio-phys Acta 1107:271–82
  • Plumb DC. (1999). Veterinary drug handbook. White Bear Lake: PharmaVet Publishing
  • Pople PV, Singh KK. (2006). Development and evaluation of topical formulation containing solid lipid nanoparticles of vitamin A. AAPS Pharm Sci Tech 7:91
  • Reddy LH, Ghosh B. (2001). Enhancer aided in vitro permeation of atenolol and prazosin hydro-chloride through mice skin. Indian J Exp Biol 39:47–51
  • Shin SC, Choi JS. (2005). Enhanced efficacy of triprolidine by transdermal application of the EVA matrix system in rabbits and rats. Eur J Pharm Biopharm 61:14–19
  • Skalko N, Cajkovac M, Jalsˇenjak I. (1998). Liposomes with metronidazole for topical use: the choice of preparation method and vehicle. J Liposome Res 8:283–93
  • Solans C, Izquierdo P, Nolla J, et al. (2005). Nanoemulsions. Curr Opin Colloid Interface Sci 10:102–10
  • Sonneville-Aubrun O, Simonnet JT, L'Alloret F. (2004). Nanoemulsions: a new vehicle for skincare products. Adv Colloid Interface Sci 108–9:145–9
  • Tadros T, Izquierdo P, Esquena J, et al. (2004). Formation and stability of nanoemulsions. Adv Colloid Interface Sci 108–9:303–18
  • Utreja P, Jain S, Tiwary AK. (2011). Localized delivery of paclitaxel using elastic lipospmes. Formulation development and evaluation. Drug Deliv 18:367–76
  • Welles E, III K, Friddovich I. (1977). Liposome oxidation and erythrocyte lysis by enzymically generated superoxide and hydrogen peroxide. J Biol Chem 262:6121–728
  • Weyenberg W, Todorov V, Ludwig A. (2004a). Rheological evaluation of the influence of sterilisation on ocular gels using an experimental design. Die Pharmazie 59:121–5
  • Weyenberg W, Vermeire A, D'Haese E, et al. (2004b). Effect of different sterilisation methods on the properties of bioadhesive powders and ocular minitablets, and clinical evaluation. Eur J Pharm Sci 23:77–87
  • Wong-Beringer A, Jacobs RA, Guglielmo BJ. (1998). Lipid formulations of amphotericin B: clinical efficacy and toxicities. Clin Infect Dis 27:603–18
  • Zellmer S, Pfeil W, Lasch J. (1995). Interaction of phosphatidylcholine liposomes with the human stratum corneum. Biochim Biophys Acta 237:176–82

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.