The structural HCV genes delivered by MPG cell penetrating peptide are directed to enhance immune responses in mice model

References

• Aghasadeghi MR, Sadat SM, Budkowska A, et al. (2006). Evaluation of a native preparation of HCV core protein (2-122) for potential applications in immunization, diagnosis and mAb production. Iranian J Publ Health 35:1–10
   Web of Science ®Google Scholar
• Alekseeva E, Sominskaya I, Skrastina D, et al. (2009). Enhancement of the expression of HCV core gene does not enhance core-specific immune response in DNA immunization: advantages of the heterologous DNA prime, protein boost immunization regimen. Genet Vaccines Ther 7:1–7
   PubMedGoogle Scholar
• Baumert TF, Ito S, Wong DT, Liang TJ. (1998). Hepatitis C virus structural proteins assemble into virus like particles in insect cells. Virol 72:3827–36
   Web of Science ®Google Scholar
• Bolhassani A. (2011). Potential efficacy of cell-penetrating peptides for nucleic acid and drug delivery in cancer. Biochim Biophys Acta Rev Cancer 1816:232–46
   PubMed Web of Science ®Google Scholar
• Bolhassani A, Zahedifard F, Taghikhani M, Rafati S. (2008). Enhanced immunogenicity of HPV16E7 accompanied by Gp96 as an adjuvant in two vaccination strategies. Vaccine 26:3362–70
   PubMed Web of Science ®Google Scholar
• Chandler DE, Penin F, Schulten K, Chipot C. (2012). The p7 protein of Hepatitis C virus forms structurally plastic, minimalist ion channels. PLoS Comput Biol 8:e1002702. doi:10.1371/journal.pcbi.1002702
   PubMed Web of Science ®Google Scholar
• Choi SH, Kim SY, Park KJ, et al. (2004). Hepatitis C virus core protein is efficiently released into the culture medium in insect cells. J Biochem Molec Biol 37:735–40
   PubMedGoogle Scholar
• Donato GM, Rivero NA, Grillo JM, et al. (2006). Expression and processing of hepatitis C virus structural proteins in Pichia pastoris yeast. Biochem Biophys Res Commun 342:625–31
   PubMed Web of Science ®Google Scholar
• Dueñas-Carrera S. (2004). DNA vaccination against hepatitis C. Curr Opin Mol Ther 6:146–50
   PubMed Web of Science ®Google Scholar
• Fazlalipour M, Keyvani H, Monavari SHR, Mollaie HR. (2014). Recombinant core-E1E2 protein expressed in Pichia pastoris yeast, a candidate vaccine for hepatitis C virus. J Antivir Antiretrovir 6:139–47
   Google Scholar
• Gorzin Z, Gorzin AA, Tabarraei A, et al. (2014). Immunogenicity evaluation of a DNA vaccine expressing the Hepatitis C virus non-structural protein 2 gene in C57BL/6 mice. Iran Biomed J 18:1–7
   PubMedGoogle Scholar
• Guan J, Deng Y, Chen H, et al. (2015). Priming with two DNA vaccines expressing hepatitis C virus NS3 protein targeting dendritic cells elicits superior heterologous protective potential in mice. Arch Virol 160:2517–24
   PubMed Web of Science ®Google Scholar
• Gummow J, Li Y, Yu W, et al. (2015). A multi-antigenic DNA vaccine that induces broad HCV-specific T-cell responses in mice. J Virol 89:1–8
   Web of Science ®Google Scholar
• Halliday J, Klenerman P, Barnes E. (2011). Vaccination for Hepatitis C virus: closing in on an evasive target. Expert Rev Vaccines 10:659–72
   PubMed Web of Science ®Google Scholar
• Hemmat J, Yakhchali B, Khajeh KH, et al. (2011). Over-expression of full-length core protein of hepatitis C virus by Escherichia coli cultivated in stirred tank fermentor. Iran J Biotechnol 9:245–52
   Web of Science ®Google Scholar
• Jiao X, Wang RYH, Feng Z, et al. (2003). Modulation of cellular immune response against hepatitis C virus nonstructural protein 3 by cationic liposome encapsulated DNA immunization. Hepatology 37:452–60
   PubMed Web of Science ®Google Scholar
• Karpenko LI, Nekrasova NA, Ilyichev AA, et al. (2004). Comparative analysis using a mouse model of the immunogenicity of artificial VLP and attenuated Salmonella strain carrying a DNA-vaccine encoding HIV-1 polyepitope CTL-immunogen. Vaccine 22:1692–9
   PubMed Web of Science ®Google Scholar
• Keyvani H, Fazlalipour M, Monavari SHR, Mollaie HR. (2012). Hepatitis C virus-proteins, diagnosis, treatment and new approaches for vaccine development. Asian Pacific J Cancer Prev 13:5917–35
   Web of Science ®Google Scholar
• Laufer S, Restle T. (2008). Peptide-mediated cellular delivery of oligonucleotide-based therapeutics in vitro: quantitative evaluation of overall efficacy employing easy to handle reporter systems. Curr Pharm Des 14:3637–55
   PubMed Web of Science ®Google Scholar
• Linbai Y, Jinrong G, Xiaolin M, et al. (1996). Expression of E1 gene of a hepatitis C virus in E. coli and protein purification. Wuhan Univ J Natural Sci 1:279–82
   Google Scholar
• Liu Y, Li F, Qi Z, et al. (2013). The effects of HIV Tat DNA on regulating the immune response of HIV DNA vaccine in mice. Virol J 10:1–11
   PubMed Web of Science ®Google Scholar
• Ma X, Forns X, Gutierrez R, et al. (2002). DNA-based vaccination against hepatitis C virus (HCV): effect of expressing different forms of HCV E2 protein and use of CpG-optimized vectors in mice. Vaccine 20:3263–71
   PubMed Web of Science ®Google Scholar
• Mirnurollahi SM, Bolhassani A, Irani S, Davoudi N. (2015). Expression and purification of HCV core and core-E1E2 proteins in different bacterial strains. Iran J Biotech 13:e1249
   Web of Science ®Google Scholar
• Morris MC, Deshayes S, Heitz F, Divita G. (2008). Cell-penetrating peptides: from molecular mechanisms to therapeutics. Biol Cell 100:201–17
   PubMed Web of Science ®Google Scholar
• Morris M, Vidal P, Chaloin L, et al. (1997). A new peptide vector for efficient delivery of oligonucleotides into mammalian cells. Nucleic Acids Res 25:2730–6
   PubMed Web of Science ®Google Scholar
• Morris MC, Chaloin L, Méry J, et al. (1999). A novel potent strategy for gene delivery using a single peptide vector as a carrier. Nucleic Acids Res 27:3510–17
   PubMed Web of Science ®Google Scholar
• Sadeghian F, Hosseinkhani S, Alizadeh A, Hatefi A. (2012). Design, engineering and preparation of a multi-domain fusion vector for gene delivery. Int J Pharm 427:393–9
   PubMed Web of Science ®Google Scholar
• Sharma SD. (2010). Hepatitis C virus: molecular biology & current therapeutic options. Indian J Med Res 131:17–34
   PubMed Web of Science ®Google Scholar
• Swadling L, Klenerman P, Barnes E. (2013). Ever closer to a prophylactic vaccine for HCV. Expert Opin Biol Ther 13:1109–24
   PubMed Web of Science ®Google Scholar
• Torresi J, Johnson D, Wedemeyer H. (2011). Progress in the development of preventive and therapeutic vaccines for hepatitis C virus. J Hepatol 54:1273–85
   PubMed Web of Science ®Google Scholar
• Verstrepen BE, Boonstra A, Koopman G. (2015). Immune mechanisms of vaccine induced protection against chronic hepatitis C virus infection in chimpanzees. World J Hepatol 7:53–69
   PubMed Web of Science ®Google Scholar
• Yazdani-Neyshabouri SH, Aghasadeghi MR, Jahanian Najafabadi A, et al. (2012). Expression of recombinant hepatitis C virus (HCV) Core, E1 and E2 proteins by the baculovirus expression vector system. African J Microbiol Res 6:4152–7
   Web of Science ®Google Scholar
• Yousaf MZ, Idrees M, Saleem Z, et al. (2011). Expression of core antigen of HCV genotype 3a and its evaluation as screening agent for HCV infection in Pakistan. Virology 8:364. doi:10.1186/1743-422X-8-364
   Web of Science ®Google Scholar