Effect of the TLR2/MyD88/NF-κB axis on corneal allograft rejection after penetrating keratoplasty

References

• Ezon I, Shih CY, Rosen LM, et al. Immunologic graft rejection in descemet’s stripping endothelial keratoplasty and penetrating keratoplasty for endothelial disease. Ophthalmology 2013;120:1360–5
   PubMed Web of Science ®Google Scholar
• Klebe S, Coster DJ, Williams KA. Rejection and acceptance of corneal allografts. Curr Opin Organ Transplant 2009;14:4–9
   PubMed Web of Science ®Google Scholar
• Niederkorn JY. The immune privilege of corneal allografts. Transplantation 1999;67:1503–8
   PubMed Web of Science ®Google Scholar
• Yamazoe K, Yamazoe K, Shimazaki-Den S, Shimazaki J. Prognostic factors for corneal graft recovery after severe corneal graft rejection following penetrating keratoplasty. BMC Ophthalmol 2013;13:5
   PubMed Web of Science ®Google Scholar
• Faraj LA, Hashmani K, Khatib T, et al. The changing face of corneal graft rejection. Br J Ophthalmol 2012;96:1049–50
   PubMed Web of Science ®Google Scholar
• Stulting RD, Sugar A, Beck R, et al. Effect of donor and recipient factors on corneal graft rejection. Cornea 2012;31:1141–7
   PubMed Web of Science ®Google Scholar
• Bachmann B, Taylor RS, Cursiefen C. Corneal neovascularization as a risk factor for graft failure and rejection after keratoplasty: an evidence-based meta-analysis. Ophthalmology 2010;117:1300–5
   PubMed Web of Science ®Google Scholar
• Coster DJ, Williams KA. The impact of corneal allograft rejection on the long-term outcome of corneal transplantation. Am J Ophthalmol 2005;140:1112–22
   PubMed Web of Science ®Google Scholar
• Jia Z, Jiao C, Zhao S, et al. Immunomodulatory effects of mesenchymal stem cells in a rat corneal allograft rejection model. Exp Eye Res 2012;102:44–9
   PubMed Web of Science ®Google Scholar
• Elbarbry F, Ragheb A, Attia A, et al. Cyclosporine-induced changes in drug metabolizing enzymes in hyperlipemic rabbit kidneys could explain its toxicity. Xenobiotica 2010;40:772–81
   PubMed Web of Science ®Google Scholar
• Kawai T, Akira S. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat Immunol 2010;11:373–84
   PubMed Web of Science ®Google Scholar
• Tesar BM, Goldstein DR. Toll-like receptors and their role in transplantation. Front Biosci 2007;12:4221–38
   PubMed Web of Science ®Google Scholar
• Obhrai J, Goldstein DR. The role of toll-like receptors in solid organ transplantation. Transplantation 2006;81:497–502
   PubMed Web of Science ®Google Scholar
• Lambiase A, Micera A, Sacchetti M, et al. Toll-like receptors in ocular surface diseases: overview and new findings. Clin Sci (Lond) 2011;120:441–50
   PubMed Web of Science ®Google Scholar
• Redfern RL, McDermott AM. Toll-like receptors in ocular surface disease. Exp Eye Res 2010;90:679–87
   PubMed Web of Science ®Google Scholar
• Bai L, Lu XH, Sun FY, et al. Blockade of toll-like receptor 2 expression and membrane translocation in rat corneal epithelial cells by glucocorticoid (TobraDex) after penetrating keratoplasty. Cornea 2011;30:1253–9
   PubMed Web of Science ®Google Scholar
• Goldstein DR. Toll like receptors and acute allograft rejection. Transpl Immunol 2006;17:11–15
   PubMed Web of Science ®Google Scholar
• Wu H, Noordmans GA, O’Brien MR, et al. Absence of MyD88 signaling induces donor-specific kidney allograft tolerance. J Am Soc Nephrol 2012;23:1701–16
   PubMed Web of Science ®Google Scholar
• Farrar CA, Keogh B, McCormack W, et al. Inhibition of TLR2 promotes graft function in a murine model of renal transplant ischemia-reperfusion injury. Faseb J 2012;26:799–807
   PubMed Web of Science ®Google Scholar
• Walker WE, Nasr IW, Camirand G, et al. Absence of innate MyD88 signaling promotes inducible allograft acceptance. J Immunol 2006;177:5307–16
   PubMed Web of Science ®Google Scholar
• Li ZY, Geng YQ, Shao YL, Zhang Y. Effect of NF-kappaB inhibitor PDTC on a herpetic stromal keratitis mouse model. Eye Sci 2012;27:188–92
   PubMedGoogle Scholar
• Holland EJ, Chan CC, Wetzig RP, et al. Clinical and immunohistologic studies of corneal rejection in the rat penetrating keratoplasty model. Cornea 1991;10:374–80
   PubMed Web of Science ®Google Scholar
• Xia D, Sanders A, Shah M, et al. Real-time polymerase chain reaction analysis reveals an evolution of cytokine mRNA production in allograft acceptor mice. Transplantation 2001;72:907–14
   PubMed Web of Science ®Google Scholar
• Lan W, Petznick A, Heryati S, et al. Nuclear Factor-kappaB: central regulator in ocular surface inflammation and diseases. Ocul Surf 2012;10:137–48
   PubMed Web of Science ®Google Scholar
• Fukumoto A, Maruyama K, Walsh T, et al. Intracellular thiol redox status regulates lymphangiogenesis and dictates corneal limbal graft survival. Invest Ophthalmol Vis Sci 2010;51:2450–8
   PubMed Web of Science ®Google Scholar
• O’Donnell MA, Ting AT. NF kappa B and ubiquitination: partners in disarming RIPK1-mediated cell death. Immunol Res 2012;54:214–26
   PubMed Web of Science ®Google Scholar
• Lim JY, Park MJ, Im KI, et al. Combination cell therapy using mesenchymal stem cells and regulatory T cells provides a synergistic immunomodulatory effect associated with reciprocal regulation of Th1/Th2 and Th17/Treg cells in a murine acute graft-versus-host disease model. Cell Transplant 2013
   Web of Science ®Google Scholar
• Ezquer F, Ezquer M, Contador D, et al. The antidiabetic effect of mesenchymal stem cells is unrelated to their transdifferentiation potential but to their capability to restore Th1/Th2 balance and to modify the pancreatic microenvironment. Stem Cells 2012;30:1664–74
   PubMed Web of Science ®Google Scholar
• Yamada J, Maruyama K, Sano Y, et al. Promotion of corneal allograft survival by the induction of oxidative macrophages. Invest Ophthalmol Vis Sci 2004;45:448–54
   PubMed Web of Science ®Google Scholar
• Karczewski J, Karczewski M, Glyda M, Wiktorowicz K. Role of TH1/TH2 cytokines in kidney allograft rejection. Transplant Proc 2008;40:3390–2
   PubMed Web of Science ®Google Scholar
• Pirenne J, Kitade H, Kawai M, et al. Regulatory cells, TH1/TH2 unbalance, and antibody-induced chronic rejection in operational tolerance induced by donor-specific blood transfusion. Transplantation 2005;79:S25–7
   PubMed Web of Science ®Google Scholar