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Research Article

Assessment of Treg/Th17 axis role in immunopathogenesis of chronic injuries of mustard lung disease

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Pages 531-541 | Received 29 Oct 2015, Accepted 30 Dec 2015, Published online: 19 Feb 2016

References

  • Malhotra RC, Ganesan K, Sugendran K, Swamy RV. Chemistry and toxicology of sulphur mustard: a review. Def Sci J 1999;49:97–116
  • Shadboorestan A. Commentary on: a review on delayed toxic effects of sulfur mustard in Iranian veterans. Daru 2012;20:99
  • Ghanei M, Harandi AA. Long term consequences from exposure to sulfur mustard: a review. Inhal Toxicol 2007;19:451–6
  • Ghanei M, Poursaleh Z, Harandi AA, et al. Acute and chronic effects of sulfur mustard on the skin: a comprehensive review. Cutan Ocul Toxicol 2010;29:269–77
  • Emami MH, Talaei M, Panahi Y, et al. Efficacy of omeprazole on cough, pulmonary function and quality of life of patients with sulfur mustard lung injury: a placebo-control, cross-over clinical trial study. J Res Med Sci 2014;19:1027–33
  • Ghanei M, Harandi AA. Molecular and cellular mechanism of lung injuries due to exposure to sulfur mustard: a review. Inhal Toxicol 2011;23:363–71
  • Chiarugi A, Moskowitz MA. Cell biology. PARP-1-a perpetrator of apoptotic cell death? Science 2002;297:200–1
  • Mansour Razavi S, Salamati P, Saghafinia M, Abdollahi M. A review on delayed toxic effects of sulfur mustard in Iranian veterans. Daru 2012;20:51
  • Li H, Liu Q, Jiang Y, et al. Disruption of th17/treg balance in the sputum of patients with chronic obstructive pulmonary disease. Am J Med Sci 2015;349:392–7
  • Wang H, Ying H, Wang S, et al. Imbalance of peripheral blood Th17 and Treg responses in patients with chronic obstructive pulmonary disease. Clin Respir J 2015;9:330–41
  • Beriou G, Costantino CM, Ashley CW, et al. IL-17-producing human peripheral regulatory T cells retain suppressive function. Blood 2009;113:4240–9
  • Murray LA, Chen Q, Kramer MS, et al. TGF-beta driven lung fibrosis is macrophage dependent and blocked by Serum amyloid P. Int J Biochem Cell Biol 2011;43:154–62
  • Wynn TA. IL-13 effector functions. Annu Rev Immunol 2003;21:425–56
  • Ghazanfari T, Faghihzadeh S, Aragizadeh H, et al. Sardasht-Iran cohort study of chemical warfare victims: design and methods. Arch Iran Med 2009;12:5–14
  • Ghotbi L, Hassan Z. The immunostatus of natural killer cells in people exposed to sulfur mustard. Int Immunopharmacol 2002;2:981–5
  • Emad A, Emad Y. CD4/CD8 ratio and cytokine levels of the BAL fluid in patients with bronchiectasis caused by sulfur mustard gas inhalation. J Inflamm 2007;4:2
  • Emad A, Emad Y. Increased in CD8 T lymphocytes in the BAL fluid of patients with sulfur mustard gas-induced pulmonary fibrosis. Respir Med 2007;101:786–92
  • Emad A, Emad Y. Levels of cytokine in bronchoalveolar lavage (BAL) fluid in patients with pulmonary fibrosis due to sulfur mustard gas inhalation. J Interferon Cytokine Res 2007;27:38–43
  • Imani S, Panahi Y, Salimian J, et al. “Epigenetic: A missing paradigm in cellular and molecular pathways of sulfur mustard lung: a prospective and comparative study.” Iran J Basic Med Sci. 2015 Aug;18(8):723–36. (PMID:26557960)
  • Harrington LE, Hatton RD, Mangan PR, et al. Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nature Immunol 2005;6:1123–32
  • Park H, Li Z, Yang XO, et al. A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nature Immunol 2005;6:1133–41
  • Galati D, De Martino M, Trotta A, et al. Peripheral depletion of NK cells and imbalance of the Treg/Th17 axis in idiopathic pulmonary fibrosis patients. Cytokine 2014;66:119–26
  • Nistala K, Moncrieffe H, Newton KR, et al. Interleukin-17-producing T cells are enriched in the joints of children with arthritis, but have a reciprocal relationship to regulatory T cell numbers. Arthritis Rheum 2008;58:875–87
  • Nistala K, Wedderburn LR. Th17 and regulatory T cells: rebalancing pro- and anti-inflammatory forces in autoimmune arthritis. Rheumatology 2009;48:602–6
  • Ji L, Zhan Y, Hua F, et al. The ratio of Treg/Th17 cells correlates with the disease activity of primary immune thrombocytopenia. PLoS One 2012;7:e50909
  • Chen JG, Lai W, Jiang Y. [Expression of Th17/Treg cell in patients with psoriasis arthritis and its clinical significance]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2012;34:617–20
  • Zhang L, Yang XQ, Cheng J, et al. Increased Th17 cells are accompanied by FoxP3(+) Treg cell accumulation and correlated with psoriasis disease severity. Clin Immunol 2010;135:108–17
  • Catana CS, Berindan Neagoe I, Cozma V, et al. Contribution of the IL-17/IL-23 axis to the pathogenesis of inflammatory bowel disease. World J Gastroenterol 2015;21:5823–30
  • Zheng Y, Wang Z, Deng L, et al. Modulation of STAT3 and STAT5 activity rectifies the imbalance of Th17 and Treg cells in patients with acute coronary syndrome. Clin Immunol 2015;157:65–77
  • Ma Y, Yuan X, Deng L, et al. Imbalanced frequencies of Th17 and Treg cells in acute coronary syndromes are mediated by IL-6-STAT3 signaling. PLoS One 2013;8:e72804
  • Dolff S, Quandt D, Feldkamp T, et al. Increased percentages of PD-1 on CD4+ T cells is associated with higher INF-γ production and altered IL-17 production in patients with systemic lupus erythematosus. Scand J Rheumatol 2014;43:307–13
  • Rabe KF, Hurd S, Anzueto A, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med 2007;176:532–55
  • Standardization of Spirometry. Update. American thoracic society. Am J Respir Crit Care Med 1994;152:1107–36
  • Quanjer PH, Tammeling GJ, Cotes JE, et al. Lung volumes and forced ventilatory flows. Report working party standardization of lung function tests, European community for steel and coal. Official statement of the European respiratory society. Euro Respir J Suppl 1993;16:5–40
  • Sharifi H, Masjedi MR, Emami H, et al. Burden of obstructive lung disease study in Tehran: research design and lung spirometry protocol. Int J Prev Med 2014;5:1439–45
  • Smyth LJ, Starkey C, Vestbo J, Singh D. CD4-regulatory cells in COPD patients. Chest 2007;132:156–63
  • Hou J, Sun Y, Hao Y, et al. Imbalance between subpopulations of regulatory T cells in COPD. Thorax 2013;68:1131–9
  • Zhu X, Gadgil AS, Givelber R, et al. Peripheral T cell functions correlate with the severity of chronic obstructive pulmonary disease. J Immunol 2009;182:3270–7
  • Lan RY, Ansari AA, Lian ZX, Gershwin ME. Regulatory T cells: development, function and role in autoimmunity. Autoimmun Rev 2005;4:351–63
  • Yao Z, Painter SL, Fanslow WC, et al. Human IL-17: a novel cytokine derived from T cells. J Immunol 1995;155:5483–6
  • Hefazi M, Attaran D, Mahmoudi M, Balali-Mood M. Late respiratory complications of mustard gas poisoning in Iranian veterans. Inhal Toxicol 2005;17:587–92
  • Tang FR, Loke WK. Sulfur mustard and respiratory diseases. Crit Rev Toxicol 2012;42:688–702
  • Vargas-Rojas MI, Ramirez-Venegas A, Limon-Camacho L, et al. Increase of Th17 cells in peripheral blood of patients with chronic obstructive pulmonary disease. Respir Med 2011;105:1648–54
  • Jones CE, Chan K. Interleukin-17 stimulates the expression of interleukin-8, growth-related oncogene-alpha, and granulocyte-colony-stimulating factor by human airway epithelial cells. Am J Respir Cell Mol Biol 2002;26:748–53
  • Molet S, Hamid Q, Davoine F, et al. IL-17 is increased in asthmatic airways and induces human bronchial fibroblasts to produce cytokines. J Allergy Clin Immunol 2001;108:430–8
  • Prause O, Bozinovski S, Anderson GP, Linden A. Increased matrix metalloproteinase-9 concentration and activity after stimulation with interleukin-17 in mouse airways. Thorax 2004;59:313–17
  • Chen Y, Thai P, Zhao YH, et al. Stimulation of airway mucin gene expression by interleukin (IL)-17 through IL-6 paracrine/autocrine loop. J Biol Chem 2003;278:17036–43
  • Monaco C, Andreakos E, Kiriakidis S, et al. T-cell-mediated signalling in immune, inflammatory and angiogenic processes: the cascade of events leading to inflammatory diseases. Curr Drug Targets Inflamm Allergy 2004;3:35–42
  • Vila J, Isaacs JD, Anderson AE. Regulatory T cells and autoimmunity. Curr Opin Hematol 2009;16:274–9
  • Tang Q, Bluestone JA. The Foxp3+ regulatory T cell: a jack of all trades, master of regulation. Nat Immunol 2008;9:239–44
  • Brodlie M, Lordan J, Ward C. Can cells other than Th17 lymphocytes be important sources of IL-17 in the lungs? Thorax 2011;66:1096. author reply -7
  • Lee SH, Goswami S, Grudo A, et al. Antielastin autoimmunity in tobacco smoking-induced emphysema. Nature Med 2007;13:567–9
  • Isajevs S, Taivans I, Strazda G, et al. Decreased FOXP3 expression in small airways of smokers with COPD. Eur Respir J 2009;33:61–7
  • Barcelo B, Pons J, Ferrer JM, et al. Phenotypic characterisation of T-lymphocytes in COPD: abnormal CD4 + CD25+ regulatory T-lymphocyte response to tobacco smoking. Eur Respir J 2008;31:555–62
  • Lohr J, Knoechel B, Wang JJ, et al. Role of IL-17 and regulatory T lymphocytes in a systemic autoimmune disease. J Exp Med 2006;203:2785–91
  • Annunziato F, Cosmi L, Santarlasci V, et al. Phenotypic and functional features of human Th17 cells. J Exp Med 2007 204:1849–61
  • Pridgeon C, Bugeon L, Donnelly L, et al. Regulation of IL-17 in chronic inflammation in the human lung. Clin Sci 2011;120:515–24
  • Noack M, Miossec P. Th17 and regulatory T cell balance in autoimmune and inflammatory diseases. Autoimmun Rev 2014;13:668–77
  • Shohrati M, Amini-Harandi A, Najafian B, et al. The role of serum level of interleukin-6 in severity of pulmonary complications of sulfur mustard injuries. Iran J Med Sci 2014;39:382–6
  • Pourfarzam S, Ghazanfari T, Yaraee R, et al. Serum levels of IL-8 and IL-6 in the long term pulmonary complications induced by sulfur mustard: Sardasht-Iran cohort study. Int Immunopharmacol 2009;9:1482–8
  • Panahi Y, Davoudi SM, Beiraghdar F, et al. Serum levels of interleukins 2, 4, 6, and 10 in veterans with chronic sulfur mustard-induced pruritus: a cross-sectional study. Skinmed 2013;11:205–9
  • Koenen HJ, Smeets RL, Vink PM, et al. Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells. Blood 2008;112:2340–52
  • Eastaff-Leung N, Mabarrack N, Barbour A, et al. Foxp3+ regulatory T cells, Th17 effector cells, and cytokine environment in inflammatory bowel disease. J Clin Immunol 2010;30:80–9
  • Josefowicz SZ, Lu LF, Rudensky AY. Regulatory T cells: mechanisms of differentiation and function. Annu Rev Immunol 2012 30:531–64
  • Chu S, Zhong X, Zhang J, et al. The expression of Foxp3 and ROR gamma t in lung tissues from normal smokers and chronic obstructive pulmonary disease patients. Int Immunopharmacol 2011;11:1780–8
  • Shi YH, Shi GC, Wan HY, et al. Coexistence of Th1/Th2 and Th17/Treg imbalances in patients with allergic asthma. Chin Med J 2011;124:1951–6
  • Zhao L, Yang J, Wang HP, Liu RY. Imbalance in the Th17/Treg and cytokine environment in peripheral blood of patients with adenocarcinoma and squamous cell carcinoma. Med Oncol 2013;30:461

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