793
Views
52
CrossRef citations to date
0
Altmetric
Research Article

Selenium potentiates the anticancer effect of cisplatin against oxidative stress and calcium ion signaling-induced intracellular toxicity in MCF-7 breast cancer cells: involvement of the TRPV1 channel

, , , &
Pages 84-93 | Received 24 Jan 2016, Accepted 19 Feb 2016, Published online: 08 Apr 2016

References

  • Gonzales CB, Kirma NB, De La Chapa JJ, et al. Vanilloids induce oral cancer apoptosis independent of TRPV1. Oral Oncol 2014;50:437–47.
  • Berridge MJ. Inositol trisphosphate and calcium signalling mechanisms. Biochim Biophys Acta 2009;1793:933–40.
  • Nazıroğlu M. Role of melatonin on calcium signaling and mitochondrial oxidative stress in epilepsy: focus on TRP channels. Tr J Biol 2015;39:813–21.
  • Nazıroğlu M. New molecular mechanisms on the activation of TRPM2 channels by oxidative stress and ADP-ribose. Neurochem Res 2007;32:1990–2001.
  • Caterina MJ, Schumacher MA, Tominaga M, et al. The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 1997;389:816–24.
  • Susankova K, Tousova K, Vyklicky L, et al. Reducing and oxidizing agents sensitize heat-activated vanilloid receptor (TRPV1) current. Mol Pharmacol 2006;70:383–94.
  • Vercelli C, Barbero R, Cuniberti B, et al. Transient receptor potential vanilloid 1 expression and functionality in MCF-7 cells: a preliminary investigation. J Breast Cancer 2014;17:332–8.
  • Vercelli C, Barbero R, Cuniberti B, et al. Expression and functionality of TRPV1 receptor in human MCF-7 and canine CF.41 cells. Vet Comp Oncol 2015;13:133–42.
  • Wu TT, Peters AA, Tan PT, et al. Consequences of activating the calcium-permeable ion channel TRPV1 in breast cancer cells with regulated TRPV1 expression. Cell Calcium 2014;56:59–67.
  • Uğuz AC, Nazıroğlu M, Espino J, et al. Selenium modulates oxidative stress induced cell apoptosis in human myeloid HL-60 cells via regulation of caspase-3, -9 and calcium influx. J Membr Biol 2009;232:15–23.
  • Shi Y. Mechanisms of caspase activation and inhibition during apoptosis. Mol Cell 2002;9:459–70.
  • Kahya MC, Nazıroğlu M, Çiğ B. Selenium reduces mobile phone (900 MHz)-induced oxidative stress, mitochondrial function, and apoptosis in breast cancer cells. Biol Trace Elem Res 2014;160:285–93.
  • Guindon J, Lai Y, Takacs SM, et al. Alterations in endocannabinoid tone following chemotherapy-induced peripheral neuropathy: effects of endocannabinoid deactivation inhibitors targeting fatty-acid amide hydrolase and monoacylglycerol lipase in comparison to reference analgesics following cisplatin treatment. Pharmacol Res 2013;67:94–109.
  • Kawai Y, Nakao T, Kunimura N, et al. Relationship of intracellular calcium and oxygen radicals to cisplatin-related renal cell injury. J Pharmacol Sci 2006;100:65–72.
  • Uozumi J, Ueda T, Yasumasu T, et al. Calcium blockers enhance cisplatin-induced nephrotoxicity in rats. Int Urol Nephrol 1992;24:549–53.
  • Nazıroğlu M, Karaoğlu A, Aksoy AO. Selenium and high dose vitamin E administration protects cisplatin-induced oxidative damage to renal, liver and lens tissues in rats. Toxicology 2004;195:221–30.
  • Nazıroğlu M, Yürekli VA. Effects of antiepileptic drugs on antioxidant and oxidant molecular pathways: focus on trace elements. Cell Mol Neurobiol 2013;33:589–99.
  • Nazıroglu M. Role of selenium on calcium signaling and oxidative stress-induced molecular pathways in epilepsy. Neurochem Res 2009;34:2181–91.
  • Wang X, Yun JW, Lei XG. Glutathione peroxidase mimic ebselen improves glucose-stimulated insulin secretion in murine islets. Antioxid Redox Signal 2014;20:191–203.
  • Liu Y, Li W, Guo M, et al. Protective role of selenium compounds on the proliferation, apoptosis, and angiogenesis of a canine breast cancer cell line. Biol Trace Elem Res 2015;169:86–93.
  • Uğuz AC, Cig B, Espino J, et al. Melatonin potentiates chemotherapy-induced cytotoxicity and apoptosis in rat pancreatic tumor cells. J Pineal Res 2012;53:91–8.
  • Savas S, Briollais L, Ibrahim-zada I, et al. A whole-genome SNP association study of NCI60 cell line panel indicates a role of Ca2+ signaling in selenium resistance. PLoS One 2010;5:e12601.
  • Köse SA, Nazıroğlu M. Selenium reduces oxidative stress and calcium entry through TRPV1 channels in the neutrophils of patients with polycystic ovary syndrome. Biol Trace Elem Res 2014;158:136–42.
  • Zeng B, Chen GL, Xu SZ. Divalent copper is a potent extracellular blocker for TRPM2 channel. Biochem Biophys Res Commun 2012;424:279–84.
  • Nazıroğlu M, Senol N, Ghazizadeh V, Yürüker V. Neuroprotection induced by N-acetylcysteine and selenium against traumatic brain injury-induced apoptosis and calcium entry in hippocampus of rat. Cell Mol Neurobiol 2014;34:895–903.
  • Nazıroğlu M, Özgül C, Küçükayaz M, et al. Selenium modulates oxidative stress-induced TRPM2 cation channel currents in transfected Chinese hamster ovary cells. Basic Clin Pharmacol Toxicol 2013;112:96–102.
  • Kahya MC, Nazıroğlu M, Çiğ B. Modulation of diabetes-induced oxidative stress, apoptosis, and Ca2+ entry through TRPM2 and TRPV1 channels in dorsal root ganglion and hippocampus of diabetic rats by melatonim and selenium. Mol Neurobiol 2016; [Epub ahead of print]. DOI 10.1007/s12035-016-9727-3.
  • Santin G, Piccolini VM, Barni S, et al. Mitochondrial fusion: a mechanism of cisplatin-induced resistance in neuroblastoma cells? Neurotoxicology 2013;34:51–60.
  • Nazıroğlu M, Ciğ B, Doğan S, et al. 45-Gz wireless devices induce oxidative stress and proliferation through cytosolic Ca2+ influx in human leukemia cancer cells. Int J Radiat Biol 2012;88:449–56.
  • Çiğ B, Nazıroğlu M. 2015. Investigation of the effects of distance from sources on apoptosis, oxidative stress and cytosolic calcium accumulation via TRPV1 channels induced by mobile phones and Wi-Fi in breast cancer cells. Biochim Biophys Acta 2015;1848:2756–65.
  • Grynkiewicz C, Poenie M, Tsien RY. A new generation of Ca2+ indicators with greatly improved fluorescence properties. J Biol Chem 1985;260:3440–50.
  • Özdemir ÜS, Nazıroğlu M, Şenol N, Ghazizadeh V. Hypericum perforatum attenuates spinal cord injury-induced oxidative stress and apoptosis in the dorsal root ganglion of rats: involvement of TRPM2 and TRPV1 channels. Mol Neurobiol 2016; [Epub ahead of print]. DOI: 10.1007/s12035-015-9292-1.
  • Mukherjea D, Jajoo S, Kaur T, et al. Transtympanic administration of short interfering (si)RNA for the NOX3 isoform of NADPH oxidase protects against cisplatin-induced hearing loss in the rat. Antioxid Redox Signal 2010;13:589–98.
  • Khasabova IA, Khasabov S, Paz J, et al. Cannabinoid type-1 receptor reduces pain and neurotoxicity produced by chemotherapy. J Neurosci 2012;32:7091–101.
  • Li P, Nijhawan D, Budihardjo I, et al. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 1997;91:479–89.
  • Liu X, Kim CN, Yang J, et al. Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell 1996;86:147–57.
  • Sung B, Prasad S, Ravindran J, et al. Capsazepine, a TRPV1 antagonist, sensitizes colorectal cancer cells to apoptosis by TRAIL through ROS-JNK-CHOP-mediated upregulation of death receptors. Free Radic Biol Med 2012;53:1977–87.
  • Santoni G, Caprodossi S, Farfariello V, et al. Antioncogenic effects of transient receptor potential vanilloid 1 in the progression of transitional urothelial cancer of human bladder. ISRN Urol 2012;2012:458238.
  • Chen SJ, Hoffman NE, Shanmughapriya S, et al. A splice variant of the human ion channel TRPM2 modulates neuroblastoma tumor growth through hypoxia-inducible factor (HIF)-1/2α. J Biol Chem 2014;289:36284–302.
  • Pan H, Chen J, Shen K, et al. Mitochondrial modulation by Epigallocatechin 3-Gallate ameliorates cisplatin induced renal injury through decreasing oxidative/nitrative stress, inflammation and NF-kB in mice. PLoS One 2015;10:e0124775.
  • Ghosh P, Singha Roy S, Basu A, et al. Sensitization of cisplatin therapy by a naphthalimide based organoselenium compound through modulation of antioxidant enzymes and p53 mediated apoptosis. Free Radic Res 2015;49:453–71.
  • Marullo R, Werner E, Degtyareva N, et al. Cisplatin induces a mitochondrial-ROS response that contributes to cytotoxicity depending on mitochondrial redox status and bioenergetic functions. PLoS One 2013;8:e81162.
  • Kinsey GR, McHowat J, Patrick KS, Schnellmann RG. Role of Ca2+-independent phospholipase A2gamma in Ca2+-induced mitochondrial permeability transition. J Pharmacol Exp Ther 2007;321:707–15.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.