52
Views
36
CrossRef citations to date
0
Altmetric
Original Article

Alphaviruses as Tools in Neurobiology and Gene Therapy

Pages 673-686 | Published online: 10 Jul 2009

References

  • Liljestrom P., Garoff H. A new generation of animal cell expression vectors based on the Semliki Forest virus replicon. Bio/Technology 1993; 9: 1356–1361
  • Xiong C., Levis R., Shen P., Schlesinger S., Rice C. M., Huang H. V. Sindbis virus: an efficient broad host range vector for gene expression in animal cells. Sceince 1989; 243: 1188–1191
  • Davis N. L., Willis L. V., Smith J. F., Johnston R. E. In vitro synthesis of infectious Venezuelan equine encephalitis virus RNA from a cDNA clone: analysis of a viable deletion mutant. Virology 1989; 171: 189–204
  • Berglund P., Tubulekas I., Liljeström P. Alphaviruses as vectors for gene delivery. Trends Biotechnol. 1996; 14: 130–134
  • Kohno A., Emi N., Kasai M., Tanimoto M., Saito H. Semliki Forest virus-based DNA expression vector: transient protein production followed by cell death. Gene Therapy 1998; 5: 415–418
  • Johanning F. W., Conny R. M., LoBuglio A. F., Wright M., Sumerel L. A., Pike M. J., Curiel D. T. A Sindbis virus mRNA polynucleotide vector achieves prolonged and high level heterologous gene expression in vivo. Nucleic Acids Res. 1995; 23: 1495–1501
  • Herweijer H., Lantendresse J. S., Williams P., Zhang G., Danko I., Schlesinger S., Wolff J. A. A plasmid-based self-amplifying Sindbis virus vector. Hum. Gene Ther. 1995; 5: 1161–1167
  • Lundstrom K., Mills A., Buell G., Allet E., Adami N., Liljeström P. High-level expression of the human neurokinin-1 receptor in mammalian cell lines using the Semliki Forest virus expression system. Eur. J. Biochem. 1994; 224: 917–921
  • Lundstrom K., personal communication
  • Olson K. E., Higgs S., Hahn C. S., Rice C. M., Carlson J. O., Beaty B. J. The expression of chloramphenicol acetyltransferase in Aedes albopictus (C6/36) cells and Aedes triseriatus mosquitoes using a double subgenomic recombinant Sindbis virus. Insect Viochem. Mol. Biol. 1994; 24: 39–48
  • Blasey H., Brethon B., Hovius R., Lundstrom K., Rey L., Bernard A. R. Large scale application of the Semliki Forest virus system: 5-HT3 receptor production. Proc. 15th ESACT Meeting. ToursFrance 1997
  • Olkkonen V. M., Liljeström P., Garoff H., Simons K., Dotti C. Expression of heterologous proteins in cultured rat hippocampal neurons using the Semliki Forest virus vector. J. Neurosci. Res. 1993; 35: 445–451
  • Paul N. L., Marsh M., McKeating J., Schulz T., Liljeström P., Garoff H., Weiss R. A. Expression of HIV-1 envelope glycoproteins by Semliki Forest virus vectors. AIDS Res. Hum. Retroviruses 1993; 9: 963–970
  • Cook D. G., Sung J., Golde T., Felsenstein K., Wojczyk B. S., Tanzi R. E., Trojanowski J. Q., Lee V. M.-Y., Doms R. W. Expression and analysis of presenilin 1 in a human neuronal system: Localization in cell bodies and dendrites. Proc. Natl. Acad. Sci. USA 1996; 93: 9223–9228
  • Monastyrskaia K., Goepfert F., Hochstrasser R., Acuna G., Leighton J., Pink J. R., Lundstrom K. Expression and intracellular localization of odorant receptors in mammalian cell lines using Semliki Forest virus vectors. J. Rec. Signal Transd. Res. 1999, in press
  • Lundstrom K., Pralong W., Martinou J.-C. Anti-apoptotic effect of Bcl-2 overexpression in RIN cells infected with Semliki Forest virus. Apoptosis 1997; 2: 189–191
  • Ulmanen I., Peränen J., Tenhunen J., Tilgmann C., Karhunen T., Panula P., Bernasconi L., Aubry J.-P., Lundstrom K. Expression and intracellular localization of catechol-o-methyltransferase in transfected mammalian cells. Eur. J. Biochem. 1997; 243: 452–459
  • Schlaeger E.-J., personal communication
  • Lundstrom K., Mills A., Allet E., Ceszkowski K., Agudo G., Chollet A., Liljeström P. High-level expression of G protein coupled receptors with the aid of the Semliki Forest virus expression system. J. Rec. Signal Transd. Res. 1995; 15: 23–32
  • Stables J., Rees S., Lundstrom K., Livingstone D., Lee M. G. High level expression of the human 5-HT1Dα receptor using the Semliki Forest virus expression system. Ann. NY Acad. Sci. 1997; 812: 229–230
  • Marshall F. H., Patel K., Lundstrom K., Camacho J., Foord S. M., Lee M. G. Characterization of [3H]-prostaglandin E2 binding to prostaglandin EP4 receptors expressed with Semliki Forest virus. Br. J. Pharmacol. 1997; 121: 1673–1678
  • Patel M., Harris C., Lundstrom K. Binding of [125I] AB-MECA to the human cloned adenosine A3 receptor using the Semliki Forest virus expression system. Drug. Dev. Res. 1997; 40: 33–40
  • Scheer A., Björklöf K., Cotecchia S., Lundstrom K. Coexpression of the α1B-adrenergic receptor and G protein subunits in mammalian cell lines using the Semliki Forest virus expression system. J. Rec. Signal. Transd. Res. 1999, in press
  • Lundstrom K., Knoflach F., Goepfert F., Schaffhauser H., Pink J. R., Borer Y., Ziltener P., Mutel V. Functional expression of metabotropic glutamate receptors in primary neurons infected with Semliki Forest virus vectors. 12th ESN Meeting. St PetersburgRussia 1998
  • Lundstrom K., Michel A., Blasey H., Bernard A. R., Hovius R., Vogel H., Surprenant A. Expression of ligand-gated ion channels with the Semliki Forest virus expression system. J. Rec. Signal Transd. Res. 1997; 17: 115–126
  • Michel A. D., Lundstrom K., Buell G. N., Surprenant A., Valera S., Humphrey P. P. A. The binding characteristics of a human bladder recombinant P2X purinoreceptor, labelled with [3H]-αβmeATP, [35S]-ATPγS or [33P]-ATP. Br. J. Pharmacol. 1996; 117: 1254–1260
  • Gorrie G. H., Vallis Y., Stephenson A., Whitfield J., Browning B., Smart T. G., Moss S. J. Assembly of GABAA receptors composed of α1 and β2 subunits in both cultured neurons and fibroblasts. J. Neurosci. 1997; 17: 6587–6596
  • Simons M., Tienari P., Dotti C. G., Beyreuther K. Two-dimensional gel mapping of the processing of the human amyloid precursor protein in rat hippocampal neurons. FEBS Lett. 1995; 368: 363–366
  • Blasey H. D., Lundstrom K., Tate S., Bernard A. R. Recombinant protein production using the Semliki Forest virus expression system. Cytotechnology 1997; 24: 65–72
  • Ikonen E., Parton R. G., Hunziker W., Simons K., Dotti C. G. Transcytosis of the polymeric immunoglobulin receptor in cultured hippocampal neurons. Curr. Biol. 1993; 3: 635–643
  • Allet B., Hochmann A., Martinou I., Berger A., Missotten M., Antonsson B., Sadoul R., Martinou J.-C., Bernasconi L. Dissecting processing and apoptotic activity of a cysteine protease by mutant analysis. J. Cell. Biol. 1996; 135: 479–486
  • Lundstrom K. Application of the SFV expression system for binding and functional studies of receptors and ion channels. Focus, 18: 53–56
  • Evans R. J., Lewis C., Virginio C., Lundstrom K., Buell G., Surprenant A., North A. Ionic permeability of, and divalent cation effects on, two ATP cation channels (P2X receptors) expressed in mammalian cells. J. Physiol. 1996; 497: 413–422
  • Lundstrom K., Hawcock A. B., Vargas A., Ward P., Thomas P., Naylor A. Effect of single point mutations of the human tachykinin NK1 receptor on antagonist affinity. Eur. J. Pharmacol. 1997; 337: 73–81
  • Lundstrom K., Turpin M. P., Large C., Robertson G., Thomas P., Lewell X.-Q. Mapping of dopamine D3 receptor binding site by pharmacological characterization of mutants expressed in CHO cells with the Semliki Forest virus system. J. Rec. Signal Transd. Res. 1998, in press
  • Lundstrom K., Turpin M. P. Proposed Schizophrenia-related gene polymorhism: Expression of the Scr9Gly mutant human dopamine D, receptor with the Semliki Forest virus system. Biochem. Biophys. Res. Comm. 1996; 225: 1068–1072
  • Simmen U., Schweitzer C., Burkard W., Schaffner W., Lundstrom K. Hypericum perforation inhibits the binding of μ- and -opioid receptor expressed with the Semliki Forest virus system. Pharmaceutica Acta Helvetiae 1998, in press
  • Simmen U., Burkard W., Schaffner W., Lundstrom K. Extracts and constituents of Hypericum perforatum inhibit the binding of various ligands to recombinant receptors expressed with the Semliki Forest virus system. J. Rec. Sign. Transd. Res. 1999, in press
  • Hovius R., Tairi A.-P., Blasey H., Bernard A., Lundstrom K., Vogel H. Characterization of a mouse serotonin 5-HT3 receptor purified from mammalian cells. J. Neurochem. 1998; 70: 824–834
  • Dryga S. A., Dryga O. A., Schlesinger S. Identification of mutations in a Sindbis virus variant able to establish persistent infection in BHK cells: the importance of a mutation in the nsP2 gene. Virology 1997; 228: 74–83
  • Berglund P., Sjöberg M., Garoff H., Atkins G. J., Sheahan B. J., Liljeström P. Semliki Forest virus expression system: production of conditionally infectious recombinant particles. Bio/Technology 1993; 11: 916–920
  • Tubulekas I., Liljeström P. Suppressors of cleavage-site mutations in the p62 envelope protein of Semliki Forest virus reveal dynamics in spike structure and function. J. Virol. 1998; 72: 2825–2831
  • Li K.-J., Garoff H. Production of infectious recombinant Moloney murine leukemia virus particlesin BHK cells using Semliki Forest virus-derived RNA expression vectors. Proc. Natl. Acad. Sci. USA 1996; 93: 11658–11663
  • Altman-Hamandzic S., Groseclose C., Ma J.-X., Hamandzic D., Vrindavanam N. S., Middaugh L. D., Parratto N. P., Sallee F. R. Expression of β-galactisidase in mouse brain: utilization of a novel nonreplicative Sindbis virus vector as a neuronal gene delivery system. Gene Therapy 1997; 4: 815–822
  • London S. D., Schmaljohn A. L., Dalrymple J. M., Rice C. M. Infectious enveloped RNA virus antigenic chimeras. Proc. Natl. Acad. Sci. USA 1992; 89: 207–211
  • Lundstrom K. Alphaviruses as expression vectors. Curr. Op. Biotech. 1997; 8: 578–582
  • Ohno K., Sawai K., Iijima Y., Levin B., Meruelo D. Cell-specific targeting of Sindbis virus vectors dispalying IgG-binding domains of protein A. Nature Biotech. 1997; 15: 763–767

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.