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Research Article

Glyceryl monooleate-based otic delivery system of ofloxacin: release profile and bactericidal activity

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Pages 361-366 | Received 19 Jul 2013, Accepted 19 Nov 2013, Published online: 06 Jan 2014

References

  • Ong YK, Chee G. Infections of the external ear. Ann Acad Med Singapore 2005;34:330–334
  • Devesa PM, Willis CM, Capper JWR. External auditory canal pH in chronic otitis externa. Clin Otolaryngol 2003;28:320–324
  • Hawke M, Wong J, Krajden S. Clinical and microbiologic features of otitis externa. J Otolaryngol 1984;13:289–295
  • Wai TK, Tong MC. A benefit-risk assessment of ofloxacin otic solution in ear infection. Drug Saf 2003;26:405–520
  • Torum B, Block SL, Avila H, et al. Efficacy of ofloxacin otic solution once daily for 7 days in the treatment of otitis externa: a multicenter, open-label, phase III trial. Clin Ther 2004;26:1046–1054
  • Engstrom S. Drug delivery from cubic and other lipid-water phases. Lipid Technol 1990;2:42–45
  • Hyde ST, Ericsson B, Andersson S, Larsson K. A cubic structure consisting of a lipid bilayer forming in infinite periodic minimum surface of the gyriod type in the glycerylmonooleate-water system. Z Krystallogr 1984;168:213–219
  • Larsson K. Cubic lipid-water phases. Structures and biomembrane aspects. J Phys Chem 1989;93:7304–7314
  • Wyatt DM, Dorschel D. A cubic-phase delivery system composed of glyceryl monooleate and water for sustained release of water-soluble drugs. Pharm Technol 1989;10:116–130
  • Ganguly S, Dash AK. A novel in situ gel for sustained drug delivery and targeting. Int J Pharm 2004;276:83–92
  • Rosevear FB. The microscopy of the liquid crystalline neat and middle phases of soaps and synthetic detergents. J Am Oil Chem Soc 1954;31:628–639
  • Rigter PL, Peppas NA. A simple equation for description of solute release. II. Fickian and anomalous release from swellable devices. J Control Release 1987;5:37–42
  • Clinical Laboratory Standards Institute. Performance standards for antimicrobial susceptibility testing: fifteenth information supplement M110-S15. Wayne (PA): CLSI; 2005
  • Fresta M, Guccione S, Beccari AR, et al. Combining molecular modeling with experimental methodologies: mechanism of membrane permeation and accumulation of ofloxacin. Bioorg Med Chem 2002;10:3871–3889
  • Lara MG, Vit’oria M, Bentley LB, Collett JH. In vitro drug release mechanism and drug loading studies of cubic phase gels. Int J Pharmaceutics 2005;293:241–250
  • Chang CM, Bodmeier R. Swelling of and drug release from monoglyceride based drug delivery systems. J Pharm Sci 1997;86:747–752
  • Geraghty PB, Attwood D, Collett JH, Dandiker Y. The in vitro release of some antimuscarinic drugs from monoolein/water lyotropic crystalline gels. Pharm Res 1996;13:1265–1271
  • Swiatlo E, Moore E, Watt J, McDaniel LS. In vitro activity of four fluoroquinolones against clinical isolates of Pseudomonas aeruginosa determined by the E test. Int J Antimicrob Agents 2000;15:73–76

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