References
- Hebert LE, Weuve J, Scherr PA, Evans DA. Alzheimer disease in the United States (2010–2050) estimated using the 2010 census. Neurology 2013;80:1778–1783
- Sathyan G, Ritschel WA, Hussain AS. Transdermal delivery of tacrine: I. Identification of a suitable delivery vehicle. Int J Pharm 1995;114:75–83
- Upasani RS, Banga AK. Response surface methodology to investigate the iontophoretic delivery of tacrine hydrochloride. Pharm Res 2004;21:2293–2299
- Kankkunen T, Sulkava R, Vuorio M, et al. Transdermal iontophoresis of tacrine in vivo. Pharm Res 2002;19:704–707
- Ackaert OW, Van Smeden J, De Graan J, et al. Mechanistic studies of the transdermal iontophoretic delivery of 5-OH-DPAT in vitro. J Pharm Sci 2010;99:275–285
- Cazares-Delgadillo J, Balaguer-Fernandez C, Calatayud-Pascual A, et al. Transdermal iontophoresis of dexamethasone sodium phosphate in vitro and in vivo: effect of experimental parameters and skin type on drug stability and transport kinetics. Eur J Pharm Biopharm 2010;75:173–178
- Kolli CS, Chadha G, Xiao J, et al. Transdermal iontophoretic delivery of selegiline hydrochloride, in vitro. J Drug Target 2010;18:657–664
- Kumar MG, Lin S. Transdermal iontophoresis of hydromorphone across hairless rat skin in vitro. Pharm Dev Technol 2009;14:106–115
- Luzardo-Alvarez A, Delgado-Charro MB, Blanco-Mendez J. Iontophoretic delivery of ropinirole hydrochloride: effect of current density and vehicle formulation. Pharm Res 2001;18:1714–1720
- Nugroho AK, Li G, Grossklaus A, et al. Transdermal iontophoresis of rotigotine: influence of concentration, temperature and current density in human skin in vitro. J Control Release 2004;96:159–167
- Cazares-Delgadillo J, Ganem-Rondero A, Quintanar-Guerrero D, et al. Using transdermal iontophoresis to increase granisetron delivery across skin in vitro and in vivo: effect of experimental conditions and a comparison with other enhancement strategies. Eur J Pharm Sci 2010;39:387–393
- Jaskari T, Vuorio M, Kontturi K, et al. Controlled transdermal iontophoresis by ion-exchange fiber. J Control Release 2000;67:179–190
- Hirsch AC, Upasani RS, Banga AK. Factorial design approach to evaluate interactions between electrically assisted enhancement and skin stripping for delivery of tacrine. J Control Release 2005;103:113–121
- Bradley Phipps J, Gyory JR. Transdermal ion migration. Adv Drug Deliv Rev 1992;9:137–176
- Vemulapalli V, Yang Y, Friden PM, Banga AK. Synergistic effect of iontophoresis and soluble microneedles for transdermal delivery of methotrexate. J Pharm Pharmacol 2008;60:27–33
- Batheja P, Thakur R, Michniak B. Transdermal iontophoresis. Expert Opin Drug Deliv 2006;3:127–138
- Nair VB, Panchagnula R. Influence of electrical parameters in the iontophoretic delivery of a small peptide: in vitro studies using arginine–vasopressin as a model peptide. Farmaco 2004;59:583–593
- Fatouros DG, Bouwstra JA. Iontophoretic enhancement of timolol across human dermatomed skin in vitro. J Drug Target 2004;12:19–24
- Kasting GB, Keister JC. Application of electrodiffusion theory for a homogeneous membrane to iontophoretic transport through skin. J Control Release 1989;8:195–210
- Fang JY, Sung KC, Wang JJ, et al. The effects of iontophoresis and electroporation on transdermal delivery of buprenorphine from solutions and hydrogels. J Pharm Pharmacol 2002;54:1329–1337
- Medi BM, Singh J. Electronically facilitated transdermal delivery of human parathyroid hormone (1–34). Int J Pharm 2003;263:25–33
- Stamatialis DF, Rolevink HH, Koops GH. Passive and iontophoretic controlled delivery of salmon calcitonin through artificial membranes. Curr Drug Deliv 2004;1:137–143
- Camel E, O'Connell M, Sage B, et al. The effect of saline iontophoresis on skin integrity in human volunteers. I. Methodology and reproducibility. Fundam Appl Toxicol 1996;32:168–178
- Jadoul A, Bouwstra J, Préat V. Effects of iontophoresis and electroporation on the stratum corneum: review of the biophysical studies. Adv Drug Deliv Rev 1999;35:89–105
- Inada H, Ghanem AH, Higuchi WI. Studies on the effects of applied voltage and duration on human epidermal membrane alteration/recovery and the resultant effects upon iontophoresis. Pharm Res 1994;11:687–697
- Calatayud-Pascual MA, Balaguer-Fernandez C, Serna-Jimenez CE, et al. Effect of iontophoresis on in vitro transdermal absorption of almotriptan. Int J Pharm 2011;416:189–194
- Vuorio M, Murtomaki L, Hirvonen J, Kontturi K. Ion-exchange fibers and drugs: a novel device for the screening of iontophoretic systems. J Control Release 2004;97:485–492
- Rodriguez Bayon AM, Guy RH. Iontophoresis of nafarelin across human skin in vitro. Pharm Res 1996;13:798–800
- Lee SH, Choi EH, Feingold KR, et al. Iontophoresis itself on hairless mouse skin induces the loss of the epidermal calcium gradient without skin barrier impairment. J Invest Dermatol 1998;111:39–43
- Khan A, Yasir M, Asif M, et al. Iontophoretic drug delivery: history and applications. J Appl Pharm Sci 2011;1:11–24
- Nair V, Pillai O, Poduri R, Panchagnula R. Transdermal iontophoresis. Part I: basic principles and considerations. Methods Find Exp Clin Pharmacol 1999;21:139–151
- Nugroho AK, Li GL, Danhof M, Bouwstra JA. Transdermal iontophoresis of rotigotine across human stratum corneum in vitro: influence of pH and NaCl concentration. Pharm Res 2004;21:844–850
- Wang H, Hou HM. Improvement of transdermal permeation of captopril by iontophoresis. Acta Pharmacol Sin 2000;21:591–595
- Hirvonen J, Kalia YN, Guy RH. Transdermal delivery of peptides by iontophoresis. Nat Biotechnol 1996;14:1710–1713
- Jacobsen J. Buccal iontophoretic delivery of atenolol. HCl employing a new in vitro three-chamber permeation cell. J Control Release 2001;70:83–95
- Yoshida NH, Roberts MS. Role of conductivity in iontophoresis. 2. Anodal iontophoretic transport of phenylethylamine and sodium across excised human skin. J Pharm Sci 1994;83:344–350
- Dixit N, Bali V, Baboota S, et al. Iontophoresis – an approach for controlled drug delivery: a review. Curr Drug Deliv 2007;4:1–10
- Guffey JS, Rutherford MJ, Payne W, Phillips C. Skin pH changes associated with iontophoresis. J Orthop Sports Phys Ther 1999;29:656–660
- Sanderson JE, Caldwell RW, Hsiao J, et al. Noninvasive delivery of a novel inotropic catecholamine: iontophoretic versus intravenous infusion in dogs. J Pharm Sci 1987;76:215–218
- Mudry B, Guy RH, Delgado-Charro MB. Transport numbers in transdermal iontophoresis. Biophys J 2006;90:2822–2830
- Lin R-Y, Ou Y-C, Chen W-Y. The role of electroosmotic flow on in-vitro transdermal iontophoresis. J Control Release 1997;43:23–33
- Kalia YN, Naik A, Garrison J, Guy RH. Iontophoretic drug delivery. Adv Drug Deliv Rev 2004;56:619–658
- Kelly AE, Ou HD, Withers R, Dotsch V. Low-conductivity buffers for high-sensitivity NMR measurements. J Am Chem Soc 2002;124:12013–12019