293
Views
28
CrossRef citations to date
0
Altmetric
Research Article

Monitoring the concentration of flowing pharmaceutical powders in a tableting feed frame

, , &
Pages 699-705 | Received 03 May 2015, Accepted 22 Sep 2015, Published online: 28 Oct 2015

References

  • FDA, Guidance for industry PAT—A framework for innovative pharmaceutical, development, manufacturing and quality assurance. Rockville, Maryland: Government Printing Office; 2004
  • Pestieau A, Krier F, Thoorens G, et al. Towards a real time release approach for manufacturing tablets using NIR spectroscopy. J Pharm Biomed Anal 2014;98:60–67
  • De Beer TRM, Burggraeve A, Fonteyne M, et al. Near infrared and Raman spectroscopy for the in-process monitoring of pharmaceutical production processes. Int J Pharm 2011;417:32–47
  • García-Muñoz S, Gierer DS. Coating uniformity assessment for colored immediate release tablets using multivariate image analysis. Int J Pharm 2010;395:104–113
  • Guay JM, Lapointe-Garant PP, Gosselin R, et al. Development of a multivariate light-induced fluorescence (LIF) PAT tool for in-line quantitative analysis of pharmaceutical granules in a V-blender. Eur J Pharm Biopharm 2014;86:524–531
  • Rajalahti T, Kvalheim OM. Multivariate data analysis in pharmaceutics: a tutorial review. Int J Pharm 2011;417:280–290
  • Moes JJ, Ruijken MM, Gout E, et al. Application of process analytical technology in tablet process development using NIR spectroscopy: blend uniformity, content uniformity and coating thickness measurements. Int J Pharm 2008;357:108–118
  • Wang HG, Senior PR, Mann R, Yang WQ. Online measurement and control of solids moisture in fluidised bed dryers. Chem Eng Sci 2009;64:2893–2902
  • Ward HW, Blackwood DO, Polizzi M, Clarke H. Monitoring blend potency in a tablet press feed frame using near infrared spectroscopy. J Pharm Biomed Anal 2013;80:18–23
  • Wahl PR, Fruhmann G, Sacher S, et al. “PAT for tableting: inline monitoring of API and excipients via NIR spectroscopy. Eur J Pharm Biopharm 2014;87:271–278
  • Macgregor JF, Bharati MH, Yu H. Multivariate image analysis for process monitoring and control. Ind Eng Chem Res 1998;37:4715–4724

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.