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Research Article

Localized delivery of methylprednisolone sodium succinate with polymeric nanoparticles in experimental injured spinal cord model

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Pages 972-981 | Received 16 Oct 2015, Accepted 12 Jan 2016, Published online: 19 Feb 2016

References

  • Novikova LN, Novikov LN, Kellerth JO. Biopolymers and biodegradable smart implants for tissue regeneration spinal cord injury. Curr Opin Neurol 2003;2:801–805.
  • Blight AR, Zimber MP. Acute spinal cord injury: pharmacotherapy and drug development perspectives. Curr Opin Investig Drugs 2001;2:801–808.
  • Merola A, O’Brien MF, Castro BA, et al. Histologic characterization of acute spinal cord injury treated with intravenous methylprednisolone. J Orthop Trauma 2002;16:155–161.
  • Geisler FH, Dorsey FC, Coleman WP. Past and current clinical-studies with Gm-1 ganglioside in acute spinal-cord injury. Ann Emerg Med 1993;22:1041–1047.
  • Samantaray S, Smith JA, Das A, et al. Low dose estrogen prevents neuronal degeneration and microglial reactivity in an acute model of spinal cord injury: effect of dosing, route of administration, and therapy delay. Neurochem Res 2011;36:1809–1816.
  • Bhang SH, Jeon O, Choi CY, et al. Controlled release of nerve growth factor from fibrin gel. J Biomed Mater Res A 2007;80:998–1002.
  • Gaviria M, Privat A, d’Arbigny P, et al. Neuroprotective effects of a novel NMDA antagonist, gacyclidine, after experimental contusive spinal cord injury in adult rats. Brain Res 2000;874:200–209.
  • Hall ED, Wolf DL. A pharmacological analysis of the pathophysiological mechanisms of posttraumatic spinal cord ischemia. J Neurosurg 1986;64:951–961.
  • Holaday JW, Faden AI. Naloxone acts at central opiate receptors to reverse hypotension, hypothermia and hypoventilation in spinal shock. Brain Res 1980;189:295–300.
  • Liu-Snyder P, Ben Borgens R, Shi R. Hydralazine rescues PC12 cells from acrolein-mediated death. J Neurosci Res 2006;84:219–227.
  • Neumann S, Bradke F, Tessier-Lavigne M, Basbaum AI. Regeneration of sensory axons within the injured spinal cord induced by intraganglionic cAMP elevation. Neuron 2002;34:885–893.
  • Pointillart V, Petitjean ME, Wiart L, et al. Pharmacological therapy of spinal cord injury during the acute phase. Spinal Cord 2000;38:71
  • Taylor SJ, McDonald JW, Sakiyama-Elbert SE. Controlled release of neurotrophin-3 from fibrin gels for spinal cord injury. J Control Release 2004;98:281–294.
  • Becker D, McDonald JW 3rd. Approaches to repairing the damaged spinal cord: overview. Handb Clin Neurol 2012;109:445–461
  • Bracken MB. Steroids for acute spinal cord injury. Cochrane Database Syst Rev 2012;1:CD001046
  • Koszdin KL, Shen DD, Bernards CM. Spinal cord bioavailability of methylprednisolone after intravenous and intrathecal administration: the role of P-glycoprotein. Anesthesiology 2000;92:156–163.
  • Young W. NASCIS. National Acute Spinal Cord Injury Study. J Neurotrauma 1990;7:113–114.
  • Kwon BK, Tetzlaff W, Grauer JN, et al. Pathophysiology and pharmacologic treatment of acute spinal cord injury. Spine J 2004;4:451–464.
  • Hall ED, Wolf DL, Braughler JM. Effects of a single large dose of methylprednisolone sodium succinate on experimental posttraumatic spinal cord ischemia. Dose–response and time–action analysis. J Neurosurg 1984;61:124–130.
  • Bracken MB, Shepard MJ, Collins WF, et al. A randomized, controlled trial of methylprednisolone or naloxone in the treatment of acute spinal-cord injury. New Engl J Med 1990;323:1209
  • Hugenholtz H, Cass DE, Dvorak MF, et al. High-dose methylprednisolone for acute closed spinal cord injury – only a treatment option. Can J Neurol Sci 2002;29:227–235.
  • Hurlbert RJ, Hadley MN, Walters BC, et al. Pharmacological therapy for acute spinal cord injury. In: Quality AfHRa, ed. Guidelines for the management of acute cervical spine and spinal cord injuries. Rockville (MD): U.S. Department of Health & Human Services, The National Guideline Clearing House; 2015
  • Hurlbert RJ, Hadley MN, Walters BC, et al. Pharmacological therapy for acute spinal cord injury. Neurosurgery 2015;76:S71–S83.
  • Consortium for Spinal Cord M. Early acute management in adults with spinal cord injury: a clinical practice guideline for health-care professionals. J Spinal Cord Med 2008;31:403–479.
  • Hurlbert RJ. Methylprednisolone for acute spinal cord injury: an inappropriate standard of care. J Neurosurg 2000;93:1–7.
  • Deer TR, Raso LJ, Garten TG. Inflammatory mass of an intrathecal catheter in patients receiving baclofen as a sole agent: a report of two cases and a review of the identification and treatment of the complication. Pain Med 2007;8:259–262.
  • White-Schenk D, Shi R, Leary JF. Nanomedicine strategies for treatment of secondary spinal cord injury. Int J Nanomedicine 2015;10:923–938.
  • Gaillard PJ, Appeldoorn CC, Rip J, et al. Enhanced brain delivery of liposomal methylprednisolone improved therapeutic efficacy in a model of neuroinflammation. J Control Release 2012;164:364–369.
  • Reijerkerk A, Appeldoorn CC, Rip J, et al. Systemic treatment with glutathione PEGylated liposomal methylprednisolone (2B3-201) improves therapeutic efficacy in a model of ocular inflammation. Investig Ophthalmol Vis Sci 2014;55:2788–2794.
  • Bethea JR. Spinal cord injury-induced inflammation: a dual-edged sword. Progr Brain Res 2000;128:33–42.
  • Shoichet MS, Tate CC, Baumann MD, LaPlaca MC. Strategies for regeneration and repair in the injured central nervous system. In: Reichert WM, ed. Indwelling neural implants: strategies for contending with the in vivo environment. Boca Raton (FL): CRC Press; 2008
  • Chvatal SA, Kim YT, Bratt-Leal AM, et al. Spatial distribution and acute anti-inflammatory effects of methylprednisolone after sustained local delivery to the contused spinal cord. Biomaterials 2008;29:1967–1975.
  • Kita R, Takahashi A, Kaibara M, Kubota K. Formation of fibrin gel in fibrinogen-thrombin system: static and dynamic light scattering study. Biomacromolecules 2002;3:1013–1020.
  • Spotnitz WD. Fibrin sealant: past, present, and future: a brief review. World J Surg 2010;34:632–634.
  • Jeon O, Kang SW, Lim HW, et al. Long-term and zero-order release of basic fibroblast growth factor from heparin-conjugated poly(l-lactide-co-glycolide) nanospheres and fibrin gel. Biomaterials 2006;27:1598–1607.
  • Tredwell S, Jackson JK, Hamilton D, et al. Use of fibrin sealants for the localized, controlled release of cefazolin. Can J Surg 2006;49:347–352.
  • Marone P, Monzillo V, Segu C, Antoniazzi E. Antibiotic-impregnated fibrin glue in ocular surgery: in vitro antibacterial activity. Ophthalmologica 1999;213:12–15.
  • Kram HB, Bansal M, Timberlake O, Shoemaker WC. Antibacterial effects of fibrin glue-antibiotic mixtures. J Surg Res 1991;50:175–178.
  • Chung YI, Ahn KM, Jeon SH, et al. Enhanced bone regeneration with BMP-2 loaded functional nanoparticle-hydrogel complex. J Control Release 2007;121:91–99.
  • Bilensoy E, Sarisozen C, Esendagli G, et al. Intravesical cationic nanoparticles of chitosan and polycaprolactone for the delivery of Mitomycin C to bladder tumors. Int J Pharm 2009;371:170–176.
  • Nacar OA, Eroglu H, Cetinalp NE, et al. Systemic administration of atorvastatin improves locomotor functions and hyperacute-acute response after experimental spinal cord injury: an ultrastructural and biochemical analysis. Turk Neurosurg 2014;24:337–343.
  • Turkoglu OF, Eroglu H, Okutan O, et al. A comparative study of treatment for brain edema: magnesium sulphate versus dexamethasone sodium phosphate. J Clin Neurosci 2008;15:60–65.
  • Basso DM, Beattie MS, Bresnahan JC. Graded histological and locomotor outcomes after spinal cord contusion using the NYU weight-drop device versus transection. Exp Neurol 1996;139:244–256.
  • Kaptanoglu E, Palaoglu S, Surucu HS, et al. Ultrastructural scoring of graded acute spinal cord injury in the rat. J Neurosurg 2002;97:49–56.
  • Crielaard BJ, Lammers T, Schiffelers RM, Storm G. Drug targeting systems for inflammatory disease: one for all, all for one. J Control Release 2012;161:225–234.
  • Barichello JM, Morishita M, Takayama K, Nagai T. Encapsulation of hydrophilic and lipophilic drugs in PLGA nanoparticles by the nanoprecipitation method. Drug Dev Ind Pharm 1999;25:471–476.
  • Pinto Reis C, Neufeld RJ, Ribeiro AJ, Veiga F. Nanoencapsulation I. Methods for preparation of drug-loaded polymeric nanoparticles. Nanomedicine Nanotechnol Biol Med 2006;2:8–21.
  • Bilati U, Allemann E Doelker E. Poly(d,l-lactide-co-glycolide) protein-loaded nanoparticles prepared by the double emulsion method – processing and formulation issues for enhanced entrapment efficiency. J Microencapsul 2005;22:205–214.
  • Vrignaud S, Benoit JP, Saulnier P. Strategies for the nanoencapsulation of hydrophilic molecules in polymer-based nanoparticles. Biomaterials 2011;32:8593–8604.
  • Patel AR, Kulkarni S, Nandekar TD, Vavia PR. Evaluation of alkyl polyglucoside as an alternative surfactant in the preparation of peptide-loaded nanoparticles. J Microencapsul 2008;25:531–540.
  • Garti N, Bisperink C. Double emulsions: progress and applications. Curr Opin Coll Interface Sci 1998;3:657–667.
  • Kim YT, Caldwell JM, Bellamkonda RV. Nanoparticle-mediated local delivery of methylprednisolone after spinal cord injury. Biomaterials 2009;30:2582–2590
  • Anderson BD, Taphouse V. Initial rate studies of hydrolysis and acyl migration in methylprednisolone 21-hemisuccinate and 17-hemisuccinate. J Pharm Sci 1981;70:181–186.
  • Herman BD, Sinclair BD, Milton N, Nail SL. The effect of bulking agent on the solid-state stability of freeze-dried methylprednisolone sodium succinate. Pharm Res 1994;11:1467–1473.
  • Punnia-Moorthy A. Buffering capacity of normal and inflamed tissues following the injection of local anaesthetic solutions. Br J Anaesth 1988;61:154–159.
  • Ueno T, Tsuchiya H, Mizogami M, Takakura K. Local anesthetic failure associated with inflammation: verification of the acidosis mechanism and the hypothetic participation of inflammatory peroxynitrite. J Inflam Res 2008;1:41–48.
  • Xu J, Fan G, Chen S, et al. Methylprednisolone inhibition of TNF-alpha expression and NF-kB activation after spinal cord injury in rats. Brain Res Mol Brain Res 1998;59:135–142.
  • Gal P, Kravcukova P, Mokry M, Kluchova D. Chemokines as possible targets in modulation of the secondary damage after acute spinal cord injury: a review. Cell Mol Neurobiol 2009;29:1025–1035
  • Popovich PG, Wei P, Stokes BT. Cellular inflammatory response after spinal cord injury in Sprague-Dawley and Lewis rats. J Comp Neurol 1997;377:443–464.
  • Springer JE, Azbill RD, Knapp PE. Activation of the caspase-3 apoptotic cascade in traumatic spinal cord injury. Nat Med 1999;5:943–946.
  • Gerndt SJ, Rodriguez JL, Pawlik JW, et al. Consequences of high-dose steroid therapy for acute spinal cord injury. J Trauma 1997;42:279–284.
  • Galandiuk S, Raque G, Appel S, Polk HC. Jr The two-edged sword of large-dose steroids for spinal cord trauma. Ann Surg 1993;218:419–425. discussion 25–27
  • Schafer V, von Briesen H, Andreesen R, et al. Phagocytosis of nanoparticles by human immunodeficiency virus (HIV)-infected macrophages: a possibility for antiviral drug targeting. Pharm Res 1992;9:541–546.
  • Mautes AE, Weinzierl MR, Donovan F, Noble LJ. Vascular events after spinal cord injury: contribution to secondary pathogenesis. Phys Ther 2000;80:673–687.

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