92
Views
7
CrossRef citations to date
0
Altmetric
Technical Note

In Vitro Release of Acyclovir from Semisolid Dosage Forms: Effect of Cyclodextrin and Polyethylene Glycol

, &
Pages 565-570 | Received 01 Oct 1997, Accepted 17 Feb 1998, Published online: 27 Sep 2008

References

  • Hayden F. G. Antimicrobial agents. Goodman and Gillman's The Pharmacological Basis of Therapeutics9th ed., J. G. Hardman, L. E. Limbird, P. B. Molinoff, R. W. Ruddon, A. G. Gillman. McGraw Hill, New York 1996; 1191–1198
  • Maudgal P. C. K., De Clercq Descamps J., Missotten L. Topical treatment of experimental herpes simplex keratouveitis with 2′-O-glycylacyclovir. A water-soluble ester of acyclovir. Arch. Ophthalmol. 1984; 102: 140–142
  • Giammona G., Puglisi G., Cavallaro G., Spadaro A., Pitrresi G. Chemical stability and bioavailability of acyclovir coupled to α, β-poly(N-2-hydroxyethyl)-DL-aspartamide. J. Controlled Release 1995; 33: 261–271
  • Corrigan O. I., Stanley C. T. Mechanism of drug dissolution rate enhancement from β-cyclodextrin drug systems. J. Pharm. Pharmacol. 1982; 34: 621–626
  • Nozawa Y., Yamamoto A. Effects of roll mixing with β-cyclodextrin on enhancing solubilities of water insoluble drug. Pharm. Acta. Helv. 1989; 64: 24–29
  • Sheu M. T., Yeh C. M., Sokoloski T. D. Characterization and dissolution of fenofibrate solid dispersion systems. Int. J. Pharm. 1994; 103: 137–146
  • Serajuddin A. T., Sheen P. C., Augstine M. A. Improved dissolution of a poorly water-soluble drug from solid dispersions in polyethylene glycol: polysorbate 80 mixtures. J. Pharm. Sci. 1990; 79: 463–464
  • Sheen P. C., Khetarpal V. K., Cariola C. M., Rowlings C. E. Formulation studies of a poorly water soluble drug in solid dispersions to improve bioavailability. Int. J. Pharm. 1995; 118: 221–227
  • Skelly J. P., Shah V. P., Maibach H. I., Guy R. H., Wester R. C., Flynn G., Yacobi A. FDA and AAPS Report of the workshop on principles and practices of in vitro percutaneous penetration studies: relevance to bioavailability and bioequivalence. Pharm. Res. 1987; 4: 265–267
  • Behme R. J., Kensler T. T., Brooke D. A new technique for determining in vitro release rates of drugs from creams. J. Pharm. Sci. 1982; 71: 1303–1305
  • Shah V. P., Elkins J. S., Lam S. Y., Skelly J. P. Determination of in vitro drug release from hydrocortisone creams. Int. J. Pharm. 1989; 53: 53–59
  • Shah V. P., Elkins J. S., Hanus J., Noorizadeh C., Skelly J. P. In vitro release of hydrocortisone from topical preparations and automated procedure. Pharm. Res. 1991; 8: 55–59
  • Shah V. P., Elkins J., Skelly J. P. Relationship between in vivo skin blanching and in vitro release rate for betamethasone valerate creams. J. Pharm. Sci. 1992; 81: 104–106
  • Reifenrath W. G., Lee B., Wilson D. R., Spencer T. S. A comparison of in vitro skin permeation cells. J. Pharm. Sci. 1994; 83: 1229–1233
  • Fares H. M., Zatz J. L. Measurement of drug release from topical gels using two types of apparatus. Pharm. Technol. 1995; 19(1)52–58
  • Chattaraj S. C., Swarbrick J., Kanfer I. A simple diffusion cell to monitor drug release from semi-solid dosage forms. Int. J. Pharm. 1995; 120: 119–124
  • Higuchi T. Rate of release of medicaments from ointment base containing drug in suspension. J. Pharm. Sci. 1961; 50: 874–875
  • Higuchi W. I. Diffusional models useful in biopharmaceutics drug release rate processes. J. Pharm. Sci. 1967; 56: 315–324

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.