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Volume 3, Issue 4

Pharmaceutical Development and Technology

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Pharmaceutical Development and Technology, Volume 3, Issue 4 (1998)

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Pharmaceutical Development and Technology, Volume 3, Issue 4 (1998)

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Research Article

Article

Aqueous-Based Polymeric Dispersion: Face-Centered Cubic Design for the Development of Atenolol Gastrointestinal Therapeutic System

Srikonda V. Sastry & Mansoor A. Khan

Pages: 423-432

Published online: 27 Sep 2008

AbstractforAqueous-Based Polymeric Dispersion: Face-Centered Cubic Design for the Development of Atenolol Gastrointestinal Therapeutic System | References | PDF (740.5 KB)

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Article

Evaluation of Atomizer Performance in Production of Respirable Spray-Dried Particles

Craig A. Dunbar, Neville M. Concessio & Anthony J. Hickey

Pages: 433-441

Published online: 27 Sep 2008

AbstractforEvaluation of Atomizer Performance in Production of Respirable Spray-Dried Particles | References | PDF (763.4 KB)

84 Views
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Article

The Impact of Formulation and Process Changes on In Vitro Dissolution and the Bioequivalence of Piroxicam Capsules

Deborah A. Piscitelli, Sian Bigora, Cecil Propst, Sanjay Goskonda, Paul Schwartz, Lawrence J. Lesko, Larry Augsburger & David Young

Pages: 443-452

Published online: 27 Sep 2008

AbstractforThe Impact of Formulation and Process Changes on In Vitro Dissolution and the Bioequivalence of Piroxicam Capsules | References | PDF (939.1 KB)

345 Views
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Article

Preliminary Investigations in Matrix-Based Tablet Formulations of Diltiazem Hydrochloride Containing Succinic Acid-Treated Methylcellulose

Mukesh C. Gohel, Madhubhai M. Patel, Mahesh T. Chhabaria & Chetak P. Buaria

Pages: 453-459

Published online: 27 Sep 2008

AbstractforPreliminary Investigations in Matrix-Based Tablet Formulations of Diltiazem Hydrochloride Containing Succinic Acid-Treated Methylcellulose | References | PDF (517.6 KB)

21 Views
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Article

Prolonged Release of Drug from O/W Emulsion and Residence in Rat Nasal Cavity

Katsuyoshi Aikawa, Keiko Matsumoto, Harumi Uda, Shigeo Tanaka, Haruo Shimamura, Yukihiko Aramaki & Seishi Tsuchiya

Pages: 461-469

Published online: 27 Sep 2008

AbstractforProlonged Release of Drug from O/W Emulsion and Residence in Rat Nasal Cavity | References | PDF (734.2 KB)

67 Views
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Article

Validation of Cleaning Procedures for Highly Potent Drugs. II. Bisnafide

James Segretario, Stacy C. Cook, Cheryl L. Umbles, Joanne T. Walker, Robert W. Woodeshick, Joseph T. Rubino & James A. Shes

Pages: 471-476

Published online: 27 Sep 2008

AbstractforValidation of Cleaning Procedures for Highly Potent Drugs. II. Bisnafide | References | PDF (475.8 KB)

68 Views
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Article

Development of Controlled-Release SK&F 82526-J Buffer Bead Formulations with Tartaric Acid as the Buffer

Gopi M. Venkatesh

Pages: 477-485

Published online: 27 Sep 2008

AbstractforDevelopment of Controlled-Release SK&F 82526-J Buffer Bead Formulations with Tartaric Acid as the Buffer | References | PDF (736.8 KB)

56 Views
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Article

Extension of Clausius-Clapeyron Equation to Predict Hydrate Stability at Different Temperatures

Linna R. Chen & David J. W. Grant

Pages: 487-494

Published online: 27 Sep 2008

AbstractforExtension of Clausius-Clapeyron Equation to Predict Hydrate Stability at Different Temperatures | References | PDF (566.5 KB)

179 Views
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Article

Effect of Gastrointestinal Protein Adsorption on the In Vitro Release of AZT from Ethylcellulose Microspheres

Khawla A. Abu-Lzza & D. Robert Lu

Pages: 495-501

Published online: 27 Sep 2008

AbstractforEffect of Gastrointestinal Protein Adsorption on the In Vitro Release of AZT from Ethylcellulose Microspheres | References | PDF (667.1 KB)

26 Views
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Article

Crystallization of Bulk Samples of Partially Amorphous Spray-Dried Lactose

Patricia Darcy & Graham Buckton

Pages: 503-507

Published online: 27 Sep 2008

AbstractforCrystallization of Bulk Samples of Partially Amorphous Spray-Dried Lactose | References | PDF (426.4 KB)

55 Views
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Article

The Characterization of the Mechanical Strength of Chewable Tablets

Montserrat Corderroura Ambros, Fridrun Podczeck, Harald Podczeck & John Michael Newton

Pages: 509-515

Published online: 27 Sep 2008

AbstractforThe Characterization of the Mechanical Strength of Chewable Tablets | References | PDF (504.5 KB)

200 Views
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Article

Development and In Vitro Evaluation of Nimodipine Transdermal Formulations Using Factorial Design

Stergiana A. Giannakou, Paraskevas P. Dallas, Dimitrios M. Rekkas & Nikolaos H. Choulis

Pages: 517-525

Published online: 27 Sep 2008

AbstractforDevelopment and In Vitro Evaluation of Nimodipine Transdermal Formulations Using Factorial Design | References | PDF (842.3 KB)

62 Views
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Article

Determining the Capability of a Drug Product to Be Terminally Sterilized: A Case Study Involving a Heat-Sensitive, Oxygen-Sensitive Drug Product

Michelle R. Duncan, Pao-Li Wang & Jeanne E. Moldenhauer

Pages: 527-534

Published online: 27 Sep 2008

AbstractforDetermining the Capability of a Drug Product to Be Terminally Sterilized: A Case Study Involving a Heat-Sensitive, Oxygen-Sensitive Drug Product | References | PDF (654.1 KB)

99 Views
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Article

Identification of Formulation and Manufacturing Variables That Influence In Vitro Dissolution and In Vivo Bioavailability of Propranolol Hydrochloride Tablets

Natalie D. Eddington, Muhammad Ashraf, Larry L. Augsburger, James L. Leslie, Michael J. Fossler, Lawrence J. Lesko, Vinod P. Shah & Gurvinder Singh Rekhi

Pages: 535-547

Published online: 27 Sep 2008

AbstractforIdentification of Formulation and Manufacturing Variables That Influence In Vitro Dissolution and In Vivo Bioavailability of Propranolol Hydrochloride Tablets | References | PDF (835 KB)

212 Views
21 CrossRef citations
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Article

Glyceryl Monooleate Cubic Phase Gel as Chemical Stability Enhancer of Cefazolin and Cefuroxime

Yogesh Sadhale & Jaymin C. Shah

Pages: 549-556

Published online: 27 Sep 2008

AbstractforGlyceryl Monooleate Cubic Phase Gel as Chemical Stability Enhancer of Cefazolin and Cefuroxime | References | PDF (665.5 KB)

124 Views
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Article

Solubility Properties of Racemic Praziquantel and Its Enantiomers

Silvia Kocova El-Arini, Daniele Giron & Hans Leuenberger

Pages: 557-564

Published online: 27 Sep 2008

AbstractforSolubility Properties of Racemic Praziquantel and Its Enantiomers | References | PDF (581 KB)

259 Views
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Technical Note

Article

In Vitro Release of Acyclovir from Semisolid Dosage Forms: Effect of Cyclodextrin and Polyethylene Glycol

Sarat C. Chattaraj, Sudip K. Das & Isadore Kanfer

Pages: 565-570

Published online: 27 Sep 2008

AbstractforIn Vitro Release of Acyclovir from Semisolid Dosage Forms: Effect of Cyclodextrin and Polyethylene Glycol | References | PDF (421.7 KB)

91 Views
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Article

Using Design of Experiments (DOE) Techniques to Avoid Process Problems

Richard J. Harwood & Steven A. Molnar

Pages: 571-575

Published online: 27 Sep 2008

AbstractforUsing Design of Experiments (DOE) Techniques to Avoid Process Problems | References | PDF (392.2 KB)

40 Views
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Editorial

The Graduate Student Manuscript Awards

Patrick P. DeLuca, Raghu K. Cavatur, Jun Han & Harmeet Chadha

Page: 577

Published online: 27 Sep 2008

AbstractforThe Graduate Student Manuscript Awards | PDF (54.6 KB)

52 Views
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Free Access

Research Article

Article

Characterization of Phase Transitions During Freeze-Drying by In Situ X-ray Powder Diffractometry

Raghu K. Cavatur & Raj Suryanarayanan

Pages: 579-586

Published online: 27 Sep 2008

AbstractforCharacterization of Phase Transitions During Freeze-Drying by In Situ X-ray Powder Diffractometry | References | PDF (635.8 KB)

193 Views
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Article

Influence of Environmental Conditions on the Kinetics and Mechanism of Dehydration of Carbamazepine Dihydrate

Jun Han & Raj Suryanarayanan

Pages: 587-596

Published online: 27 Sep 2008

AbstractforInfluence of Environmental Conditions on the Kinetics and Mechanism of Dehydration of Carbamazepine Dihydrate | References | PDF (903.3 KB)

185 Views
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Article

Effect of Polytyrosine on the Hydrophobicity of Hydroxyethyl Starch Microspheres

Harmeet Chadha & Patrick P. Deluca

Pages: 597-606

Published online: 27 Sep 2008

AbstractforEffect of Polytyrosine on the Hydrophobicity of Hydroxyethyl Starch Microspheres | References | PDF (847.1 KB)

35 Views
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Book Review

Page: 607

Published online: 27 Sep 2008

AbstractforBook Review | PDF (79 KB)

5 Views
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In Memoriam

In Memoriam: Ralph F. Shangraw

A Eulogy & Larry L. Augsburger

Pages: ix-x

Published online: 27 Sep 2008

CitationforIn Memoriam: Ralph F. Shangraw | References | PDF (172.9 KB)

13 Views
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Guest Editorial

Editorial

Renaissance in Natural Products Drug Science to be the Focus of Drug Delivery

Tsuneji Nagai

Pages: xi-xii

Published online: 27 Sep 2008

CitationforRenaissance in Natural Products Drug Science to be the Focus of Drug Delivery | PDF (116.9 KB)

59 Views
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Free Access

Meeting Notice

Meeting Report

Meeting Notice

Page: xiii

Published online: 27 Sep 2008

CitationforMeeting Notice | PDF (28.5 KB)

5 Views
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Pharmaceutical Development and Technology (Vol.3, Iss.4, 1998)

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