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Amyloid
The Journal of Protein Folding Disorders
Volume 18, 2011 - Issue sup1: XIIth International Symposium on Amyloidosis From Molecular Mechanisms Towards the Cure of Systemic Amyloidoses
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Opening lecture

Functional correlates of N-terminal natriuretic peptide type B (NT-proBNP) response to therapy in cardiac light chain (AL) amyloidosis

S. PerliniCorrespondence[email protected]
,
F. MuscaDepartment of Internal Medicine, Fondazione IRCCS Policlinico San Matteo and University of Pavia, Italy
,
F. SalinaroDepartment of Internal Medicine, Fondazione IRCCS Policlinico San Matteo and University of Pavia, Italy
,
I. FracchioniDepartment of Internal Medicine, Fondazione IRCCS Policlinico San Matteo and University of Pavia, Italy
,
G. PalladiniAmyloidosis Research and Treatment Center and Department of Biochemistry, Fondazione IRCCS Policlinico San Matteo and University of Pavia, Pavia, Italy
,
L. ObiciAmyloidosis Research and Treatment Center and Department of Biochemistry, Fondazione IRCCS Policlinico San Matteo and University of Pavia, Pavia, Italy
,
R. AlbertiniAmyloidosis Research and Treatment Center and Department of Biochemistry, Fondazione IRCCS Policlinico San Matteo and University of Pavia, Pavia, Italy
,
R. MorattiAmyloidosis Research and Treatment Center and Department of Biochemistry, Fondazione IRCCS Policlinico San Matteo and University of Pavia, Pavia, Italy
,
F. LavatelliAmyloidosis Research and Treatment Center and Department of Biochemistry, Fondazione IRCCS Policlinico San Matteo and University of Pavia, Pavia, Italy
,
G. PalladiniDepartment of Internal Medicine, Fondazione IRCCS Policlinico San Matteo and University of Pavia, Italy
,
C. RapezziInstitute of Cardiology, S. Orsola-Malpighi Hospital, University of Bologna, Italy
&
G. MerliniAmyloidosis Research and Treatment Center and Department of Biochemistry, Fondazione IRCCS Policlinico San Matteo and University of Pavia, Pavia, Italy
 show all
Pages 96-97 | Published online: 18 Aug 2011

References

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  • Rapezzi C, Merlini G, Quarta CC, Riva L, Longhi S, Leone O, Salvi F, Ciliberti P, Pastorelli F, Biagini E, Systemic cardiac amyloidoses: disease profiles and clinical courses of the 3 main types. Circulation 2009;120:1203–1212.
  • Liao R, Jain M, Teller P, Connors LH, Ngoy S, Skinner M, Falk RH, Apstein CS. Infusion of light chains from patients with cardiac amyloidosis causes diastolic dysfunction in isolated mouse hearts. Circulation 2001;104:1594–1597.
  • Shi J, Guan J, Jiang B, Brenner DA, Del Monte F, Ward JE, Connors LH, Sawyer DB, Semigran MJ, Macgillivray TE, Amyloidogenic light chains induce cardiomyocyte contractile dysfunction and apoptosis via a non-canonical p38alpha MAPK pathway. Proc Natl Acad Sci USA 2010;107:4188–4193.

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