511
Views
18
CrossRef citations to date
0
Altmetric
Research Articles

Serum metabolomics reveals lipid metabolism variation between coronary artery disease and congestive heart failure: a pilot study

, , , , , , , , , , & show all
Pages 314-321 | Received 14 Dec 2012, Accepted 25 Feb 2013, Published online: 12 Apr 2013

References

  • Almeida AS, Queiroga CS, Sousa MF, et al. (2012). Carbon monoxide modulates apoptosis by reinforcing oxidative metabolism in astrocytes: role of Bcl-2. J Biol Chem 287:10761–70
  • Bolli R. (1990). Mechanism of myocardial “stunning”. Circulation 82:723–38
  • Boonman-de Winter LJ, Rutten FH, Cramer MJ, et al. (2012). High prevalence of previously unknown heart failure and left ventricular dysfunction in patients with type 2 diabetes. Diabetologia 55:2154–62
  • Braunwald E. (2012). The rise of cardiovascular medicine. Eur Heart J 33:838–45, 45a
  • Campos LA, Bader M, Baltatu OC. (2011). Brain renin-angiotensin system in hypertension, cardiac hypertrophy, and heart failure. Front Physiol 2:115.1--5
  • Colucci WS, Packer M, Bristow MR, et al. (1996). Carvedilol inhibits clinical progression in patients with mild symptoms of heart failure. US Carvedilol Heart Failure Study Group. Circulation 94:2800–6
  • Cui X, Churchill GA. (2003). Statistical tests for differential expression in cDNA microarray experiments. Genome Biol 4:210.1--10
  • Diercks DB, Owen K, Tolstikov V, Sutter M. (2012). Urinary metabolomic analysis for the identification of renal injury in patients with acute heart failure. Acad Emerg Med 19:18–23
  • Dunn W, Broadhurst D, Deepak S, et al. (2007). Serum metabolomics reveals many novel metabolic markers of heart failure, including pseudouridine and 2-oxoglutarate. Metabolomics 3:413–26
  • Dunn WB, Wilson ID, Nicholls AW, Broadhurst D. (2012). The importance of experimental design and QC samples in large-scale and MS-driven untargeted metabolomic studies of humans. Bioanalysis 4:2249–64
  • Egom EE, Mamas MA, Clark AL. (2012). The potential role of sphingolipid-mediated cell signaling in the interaction between hyperglycemia, acute myocardial infarction and heart failure. Expert Opin Ther Targets 16:791–800
  • Eriksson H. (1995). Heart failure: a growing public health problem. J Intern Med 237:135–41
  • Fabian E, Havranek F, Stork A, Fabianova J. (1971). Lipoprotein lipase and postheparin esterase activity and postheparin increase in free fatty acids after the short-term administration of a sequential contraceptive. Am J Obstet Gynecol 109:1212–13
  • Falk E. (1983). Plaque rupture with severe pre-existing stenosis precipitating coronary thrombosis. Characteristics of coronary atherosclerotic plaques underlying fatal occlusive thrombi. Br Heart J 50:127–34
  • Fillmore N, Lopaschuk GD. (2013). Targeting mitochondrial oxidative metabolism as an approach to treat heart failure. Biochim Biophys Acta 1833:857--65
  • Gheorghiade M, Bonow RO. (1998). Chronic heart failure in the United States: a manifestation of coronary artery disease. Circulation 97:282–9
  • Gottdiener JS, McClelland RL, Marshall R, et al. (2002). Outcome of congestive heart failure in elderly persons: influence of left ventricular systolic function. The Cardiovascular Health Study. Ann Intern Med 137:631–9
  • Jaswal JS, Keung W, Wang W, et al. (2011). Targeting fatty acid and carbohydrate oxidation – a novel therapeutic intervention in the ischemic and failing heart. Biochim Biophys Acta 1813:1333–50
  • Jiang H, Ge J. (2009). Epidemiology and clinical management of cardiomyopathies and heart failure in China. Heart 95:1727–31
  • Kaddurah-Daouk R, Kristal BS, Weinshilboum RM. (2008). Metabolomics: a global biochemical approach to drug response and disease. Annu Rev Pharmacol Toxicol 48:653–83
  • Katz AM. (1975). Congestive heart failure: role of altered myocardial cellular control. N Engl J Med 293:1184–91
  • Kjekshus J, Swedberg K, Snapinn S. (1992). Effects of enalapril on long-term mortality in severe congestive heart failure. CONSENSUS Trial Group. Am J Cardiol 69:103–7
  • Knapp M, Baranowski M, Lisowska A, Musial W. (2012). Decreased free sphingoid base concentration in the plasma of patients with chronic systolic heart failure. Adv Med Sci 57:100–5
  • Lainscak M, Keber I. (2003). Patient's view of heart failure: from the understanding to the quality of life. Eur J Cardiovasc Nurs 2:275–81
  • Lerman A, Zeiher AM. (2005). Endothelial function: cardiac events. Circulation 111:363–8
  • Ling XB, Cohen H, Jin J, et al. (2009). FDR made easy in differential feature discovery and correlation analyses. Bioinformatics 25:1461–2
  • Lopaschuk GD, Ussher JR, Folmes CD, et al. (2010). Myocardial fatty acid metabolism in health and disease. Physiol Rev 90:207–58
  • Lu K, Knutson CG, Wishnok JS, et al. (2012). Serum metabolomics in a Helicobacter hepaticus mouse model of Inflammatory Bowel Disease reveals important changes in the microbiome, serum peptides, and intermediary metabolism. J Proteome Res 11:4916--26
  • Mancini DM, Walter G, Reichek N, et al. (1992). Contribution of skeletal muscle atrophy to exercise intolerance and altered muscle metabolism in heart failure. Circulation 85:1364–73
  • Merry AH, Erkens PM, Boer JM, et al. (2012). Co-occurrence of metabolic factors and the risk of coronary heart disease: a prospective cohort study in the Netherlands. Int J Cardiol 155:223–9
  • Ndrepepa G, Braun S, Kastrati A, Schomig A. (2007). Area under ROC curve, sensitivity, specificity of N-terminal probrain natriuretic peptide in predicting mortality in various subsets of patients with ischemic heart disease. Clin Res Cardiol 96:763–5
  • Oliveira PJ, Carvalho RA, Portincasa P, et al. (2012). Fatty acid oxidation and cardiovascular risk during menopause: a mitochondrial connection? J Lipids 2012:1--12
  • Omori Y, Ohtani T, Sakata Y, et al. (2012). L-Carnitine prevents the development of ventricular fibrosis and heart failure with preserved ejection fraction in hypertensive heart disease. J Hypertens 30:1834–44
  • Park TS, Panek RL, Mueller SB, et al. (2004). Inhibition of sphingomyelin synthesis reduces atherogenesis in apolipoprotein E-knockout mice. Circulation 110:3465–71
  • Rosca MG, Tandler B, Hoppel CL. (2012). Mitochondria in cardiac hypertrophy and heart failure. J Mol Cell Cardiol 55:31--41
  • Segers VF, Brutsaert DL, De Keulenaer GW. (2012). Pulmonary hypertension and right heart failure in heart failure with preserved left ventricular ejection fraction: pathophysiology and natural history. Curr Opin Cardiol 27:273–80
  • Shah SH, Bain JR, Muehlbauer MJ, et al. (2010). Association of a peripheral blood metabolic profile with coronary artery disease and risk of subsequent cardiovascular events. Circ Cardiovasc Genet 3:207–14
  • Smith CA, Want EJ, O'Maille G, et al. (2006). XCMS: processing mass spectrometry data for metabolite profiling using nonlinear peak alignment, matching, and identification. Anal Chem 78:779–87
  • Stanley WC, Recchia FA, Lopaschuk GD. (2005). Myocardial substrate metabolism in the normal and failing heart. Physiol Rev 85:1093–129
  • Taegtmeyer H. (2004). Cardiac metabolism as a target for the treatment of heart failure. Circulation 110:894–6
  • Tang T, Gao MH, Hammond HK. (2012). Prospects for gene transfer for clinical heart failure. Gene Ther 19:606–12
  • Taylor AB, Mackinnon DP. (2012). Four applications of permutation methods to testing a single-mediator model. Behav Res Methods 44:806–44
  • Vacek TP, Vacek JC, Tyagi N, Tyagi SC. (2012). Autophagy and heart failure: a possible role for homocysteine. Cell Biochem Biophys 62:1–11
  • Van Brocklyn JR, Williams JB. (2012). The control of the balance between ceramide and sphingosine-L-phosphate by sphingosine kinase: oxidative stress and the seesaw of cell survival and death. Comp Biochem Physiol B Biochem Mol Biol 163:26–36
  • Wang L, Folsom AR, Eckfeldt JH. (2003). Plasma fatty acid composition and incidence of coronary heart disease in middle aged adults: the Atherosclerosis Risk in Communities (ARIC) Study. Nutr Metab Cardiovasc Dis 13:256–66
  • Wiklund S, Johansson E, Sjostrom L, et al. (2008). Visualization of GC/TOF-MS-based metabolomics data for identification of biochemically interesting compounds using OPLS class models. Anal Chem 80:115–22
  • Xia J, Yi L, Liu N, et al. (2012). Human plasma metabolic profiles of coronary heart disease by gas chromatography-mass spectrometry with Monte Carlo tree approach. Analyt Lett 45:2185–97
  • Xu Y, Heilier JF, Madalinski G, et al. (2010). Evaluation of accurate mass and relative isotopic abundance measurements in the LTQ-Orbitrap mass spectrometer for further metabolomics database building. Anal Chem 82:5490–501
  • Zelena E, Dunn WB, Broadhurst D, et al. (2009). Development of a robust and repeatable UPLC-MS method for the long-term metabolomic study of human serum. Anal Chem 81:1357–64

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.