72
Views
0
CrossRef citations to date
0
Altmetric
Papers

Human immunodeficiency virus type 1 clade B and C Tat differentially induce indoleamine 2,3-dioxygenase and serotonin in immature dendritic cells: Implications for neuroAIDS

, , , &
Pages 255-263 | Received 02 Apr 2010, Accepted 10 May 2010, Published online: 06 Jul 2010

References

  • Adham N, Zgombick JM, Bard J, Branchek TA (1998). Functional characterization of the recombinant human 5-hydroxytryptamine7(a) receptor isoform coupled to adenylate cyclase stimulation. J Pharmacol Exp Ther 287: 508–514.
  • Agaugué S, Perrin-Cocon L, Coutant F, André P, Lotteau V (2006). 1-Methyl-tryptophan can interfere with TLR signaling in dendritic cells independently of IDO activity. J Immunol 177: 2061–2071.
  • Amarapal P, Tantivanich S, Balachandra K, Matsuo K, Pitisutithum P, Chongsa-nguan M (2005). The role of the Tat gene in the pathogenesis of HIV infection. Southeast Asian J Trop Med Public Health 36: 352–361.
  • Bahr GM, Darcissac EC, Mouton Y (2003). Discordant effects of interleukin-2 on viral and immune parameters in human immunodeficiency virus-1-infected monocyte-derived mature dendritic cells. Clin Exp Immunol 132: 289–296.
  • Bartz SR, Emerman M (1999). Human immunodeficiency virus type 1 Tat induces apoptosis and increases sensitivity to apoptotic signals by up-regulating FLICE/caspase-8. J Virol 73: 1956–1963.
  • Brew BJ, Corbeil J, Pemberton L, Evans L, Saito K, Penny R, Cooper DA, Heyes MP (1995). Quinolinic acid production is related to macrophage tropic isolates of HIV-1. J NeuroVirol 1: 369–374.
  • Cameron PU, Lowe MG, Crowe SM, O'Doherty U, Pope M, Gezelter S, Steinman RM (1994). Susceptibility of dendritic cells to HIV-1 infection in vitro. J Leukoc Biol 56: 257–265.
  • Campbell GR, Watkins JD, Singh KK, Loret EP, Spector SA (2007). Human immunodeficiency virus type 1 subtype C Tat fails to induce intracellular calcium flux and induces reduced tumor necrosis factor production from monocytes. J Virol 81: 5919–5928.
  • Duvall MG, Loré K, Blaak H, Ambrozak DA, Adams WC, Santos K, Geldmacher C, Mascola JR, McMichael AJ, Jaye A, Whittle HC, Rowland-Jones SL, Koup RA (2007). Dendritic cells are less susceptible to human immunodeficiency virus type 2 (HIV-2) infection than to HIV-1 infection. J Virol 81: 13486–13498.
  • Fallarino F, Vacca C, Orabona C, Belladonna ML, Bianchi R, Marshall B, Keskin DB, Mellor AL, Fioretti MC, Grohmann U, Puccetti P (2002). Functional expression of indoleamine 2,3-dioxygenase by murine CD8apdendritic cells. Int Immunol 14: 65–68.
  • Gandhi N, Saiyed Z, Thangavel S, Rodriguez J, Rao KV, Nair MP (2009). Differential effects of HIV type 1 clade B and clade C Tat protein on expression of proinflammatory and antiinflammatory cytokines by primary monocytes. AIDS Res Hum Retroviruses 25: 691–699.
  • Geijtenbeek TB, van Kooyk Y (2003). DC-SIGN: a novel HIV receptor on DCs that mediates HIV-1 transmission. Curr Top Microbiol Immunol 276: 31–54.
  • Gordon J, Barnes NM (2003). Lymphocytes transport serotonin and dopamine: agony or ecstasy? Trends Immunol 24: 438–443.
  • Granelli-Piperno A, Moser B, Pope M, Chen D, Wei Y, Isdell F, O'Doherty U, Paxton W, Koup R, Mojsov S, Bhardwaj N, Clark-Lewis I, Baggiolini M, Steinman RM (1996). Efficient interaction of HIV-1 with purified dendritic cells via multiple chemokine coreceptors. J Exp Med 184: 2433–2438.
  • Gupta JD, Satishchandra P, Gopukumar K, Wilkie F, Waldrop-Valverde D, Ellis R, Ownby R, Subbakrishna DK, Desai A, Kamat A, Ravi V, Rao BS, Satish KS, Kumar M (2007). Neuropsychological deficits in human immunodeficiency virus type 1 clade C-seropositive adults from South India. J NeuroVirol 13: 195–202.
  • Heyes MP, Saito K, Crowley JS, Davis LE, Demitrack MA, Der M, Dilling LA, Elia J, Kruesi MJ, Lackner A (1992). Quinolinic acid and kynurenine pathway metabolism in inflammatory and non-inflammatory neurological disease. Brain 115: 1249–1273.
  • Hwu P, Du MX, Lapointe R, Do M, Taylor MW, Young HA (2006). Indoleamine 2,3-dioxygenase production by human dendritic cells results in the inhibition of T cell proliferation. J Immunol 164: 3596–3599.
  • Izmailova E, Bertley FM, Huang Q, Makori N, Miller CJ, Young RA, Aldovini A (2003). HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages. Nat Med 9: 191–197.
  • Korber B, Kuiken C, Foley B, Hanh B, McCutchan F, Mellors J, Sodroski J (1998). Human retroviruses and AIDS. A compilation and analysis of nucleic acid and amino acid sequences. Los Alamos, NM: Theoretical Biology and Biophysics Group, Los Alamos National Laboratory.
  • Kumar AM, Berger JR, Eisdorfer C, Fernandez JB, Goodkin K, Kumar M (2001). Cerebrospinal fluid 5-hydroxytryptamine and 5-hydroxyindoleacetic acid in HIV-1 infection. Neuropsychobiology 44: 13–18.
  • Lee HJ, Jeong YI, Lee TH, Jung ID, Lee JS, Lee CM, Kim JI, Joo H, Lee JD, Park YM (2007). Rosmarinic acid inhibits indoleamine 2,3-dioxygenase expression in murine dendritic cells. Biochem Pharmacol 73: 1412–1421.
  • Li W, Huang Y, Reid R, Steiner J, Malpica-Llanos T, Darden TA, Shankar SK, Mahadevan A, Satishchandra P, Nath A (2008). NMDA receptor activation by HIV-Tat protein is clade dependent. J Neurosci 28: 12190–12198.
  • Lichtner M, Marañón C, Vidalain PO, Azocar O, Hanau D, Lebon P, Burgard M, Rouzioux C, Vullo V, Yagita H, Rabourdin-Combe C, Servet C, Hosmalin A (2004). HIV type 1-infected dendritic cells induce apoptotic death in infected and uninfected primary CD4 T lymphocytes. AIDS Res Hum Retroviruses 20: 175–182.
  • Maes M, Verkerk R, Bonaccorso S, Ombelet W, Bosmans E, Scharpé S (2002). Depressive and anxiety symptoms in the early puerperium are related to increased degradation of tryptophan into kynurenine, a phenomenon which is related to immune activation. Life Sci 71: 1837–1848.
  • Manéglier B, Guillemin GJ, Clayette P, Rogez-Kreuz C, Brew BJ, Dormont D, Advenier C, Therond P, Spreux-Varoquaux O (2008). Serotonin decreases HIV-1 replication in primary cultures of human macrophages through 5-HT(1A) receptors. Br J Pharmacol 154: 174–182.
  • Martin A, Heyes MP, Salazar AM, Kampen DL, Williams J, Law WA, Coats ME, Markey SP (1992). Progressive slowing of reaction time and increasing cerebrospinal fluid concentrations of quinolinic acid in HIV-infected individuals. J Neuropsychiatry Clin Neurosci 4: 270–279.
  • Mellor AL, Munn DH (2004). IDO expression by dendritic cells: tolerance and tryptophan catabolism. Nat Rev Immunol 4: 762–774.
  • Mishra M, Vetrivel S, Siddappa NB, Ranga U, Seth P (2008). Clade-specific differences in neurotoxicity of human immunodeficiency virus-1 B and C Tat of human neurons: significance of dicysteine C30C31 motif. Ann Neurol 63: 366–376.
  • Mössner R, Lesch KP (1998). Role of serotonin in the immune system and in neuroimmune interactions. Brain Behav Immun 12: 249–271.
  • Munn DH, Shafizadeh E, Attwood JT, Bondarev I, Pashine A, Mellor AL (1999). Inhibition of T cell proliferation by macrophage tryptophan catabolism. J Exp Med 189: 1363–1372.
  • Munn DH, Sharma MD, Lee JR, Jhaver KG, Johnson TS, Keskin DB, Marshall B, Chandler P, Antonia SJ, Burgess R, Slingluff CL Jr, Mellor AL (2002). Potential regulatory function of human dendritic cells expressing indoleamine 2,3-dioxygenase. Science 297: 1867–1870.
  • Myers G, MacInnes K, Korber B (1992). The emergence of simian/human immunodeficiency viruses. AIDS Res Hum Retroviruses 8: 373–86.
  • Myint AM, Kim YK (2003). Cytokine-serotonin interaction through IDO: a neurodegeneration hypothesis of depression. Med Hypotheses 61: 519–525.
  • Nair MP, Mahajan SD, Schwartz SA, Reynolds J, Whitney R, Bernstein Z, Chawda RP, Sykes D, Hewitt R, Hsiao CB (2005). Cocaine modulates dendritic cell-specific C type intercellular adhesion molecule-3-grabbing non-integrin expression by dendritic cells in HIV-1 patients. J Immunol 174: 6617–6626.
  • Nair MP, Schwartz SA, Mahajan SD, Tsiao C, Chawda RP, Whitney R, Don Sykes BB, Hewitt R (2004). Drug abuse and neuropathogenesis of HIV infection: role of DC-SIGN and IDO. J Neuroimmunol 157: 56–60.
  • O'Connell PJ, Wang X, Leon-Ponte M, Griffiths C, Pingle SC, Ahern GP (2006). A novel form of immune signaling revealed by transmission of the inflammatory mediator serotonin between dendritic cells and T cells. Blood 107: 1010–1017.
  • Oshima T, Flores SC, Vaitaitis G, Coe LL, Joh T, Park JH, Zhu Y, Alexander B, Alexander JS (2000). HIV-1 Tat increases endothelial solute permeability through tyrosine kinase and mitogen-activated protein kinase-dependent pathways. AIDS 14: 475–482.
  • Osmanov S, Pattou C, Walker N, Schwardländer B, Esparza J (2000). Estimated global distribution and regional spread of HIV-1 genetic subtypes in the year 2000. J Acquir Immune Defic Syndr 29: 184–190.
  • Rambaut A, Robertson DL, Pybus OG, Peeters M, Holmes EC (2001). Human immunodeficiency virus. Phylogeny and the origin of HIV-1. Nature 410: 1047–1048.
  • Rao VR, Sas AR, Eugenin EA, Siddappa NB, Bimonte-Nelson H, Berman JW, Ranga U, Tyor WR, Prasad VR (2008). HIV-1 clade-specific differences in the induction of neuropathogenesis. J Neurosci 28: 10010–10016.
  • Robertson DL, Anderson JP, Bradac JA, Carr JK, Foley B, Funkhouser RK, Gao F, Hahn BH, Kalish ML, Kuiken C, Learn GH, Leitner T, McCutchan F, Osmanov S, Peeters M, Pieniazek D, Salminen M, Sharp PM, Wolinsky S, Korber B (2000). HIV-1 nomenclature proposal. Science 288: 55–56.
  • Samikkannu T, Saiyed ZM, Rao KV, Babu DK, Rodriguez JW, Papuashvili MN, Nair MP (2009). Differential regulation of indoleamine-2,3-dioxygenase (IDO) by HIV-1 clade B and C Tat protein. AIDS Rese Retrovirus 25: 329–335.
  • Sanders RW, de Jong EC, Baldwin CE, Schuitemaker JH, Kapsenberg ML, Berkhout B (2002). Differential transmission of human immunodeficiency virus type 1 by distinct subsets of effector dendritic cells. J Virol 76: 7812–7821.
  • Sei S, Saito K, Stewart SK, Crowley JS, Brouwers P, Kleiner DE, Katz DA, Pizzo PA, Heyes MP (1995). Increased human immunodeficiency virus (HIV) type 1 DNA content and quinolinic acid concentration in brain tissues from patients with HIV encephalopathy. J Infect Dis 172: 638–647.
  • Shively CA, Mirkes SJ, Lu NZ, Henderson JA, Bethea CL (2003). Soy and social stress affect serotonin neurotransmission in primates. Pharmacogenomics J 3: 114–121.
  • Smith DG, Guillemin GJ, Pemberton L, Kerr S, Nath A, Smythe GA, Brew BJ (2001). Quinolinic acid is produced by macrophages stimulated by platelet activating factor, Nef and Tat. J NeuroVirol 7: 56–60.
  • Steinman RM, Granelli-Piperno A, Pope M, Trumpfheller C, Ignatius R, Arrode G, Racz P, Tenner-Racz K (2003). The interaction of immunodeficiency viruses with dendritic cells. Curr Top Microbiol Immunol 276: 1–30.
  • Stone TW, Darlington LG (2002). Endogenous kynurenines as targets for drug discovery and development. Nat Rev Drug Disco 1: 609–620.
  • Thomas SR, Salahifar H, Mashima R, Hunt NH, Richardson DR, Stocker R (2001). Antioxidants inhibit indoleamine 2,3-dioxygenase in IFN-gamma-activated human macrophages: posttranslational regulation by pyrrolidine dithiocarbamate. J Immunol 166: 6332–6340.
  • Wichers MC, Maes M (2004). The role of indoleamine 2,3-dioxygenase (IDO) in the pathophysiology of interferon-α-induced depression. J Psychiatry Neurosci 29: 11–17.
  • Wu L, KewalRamani VN (2006). Dendritic-cell interactions with HIV: infection and viral dissemination. Nat Rev Immunol 6: 859–868.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.