Quinolinic acid production is related to macrophage tropic isolates of HIV-1

References

• Brew, Rosenblum, Cronin, Price. AIDS dementia complex and HIV-1brain infection: clinical-virological correlations. Ann Neurol 1995, (in press)
   Google Scholar
• Budka. Human immunodeficiency virus (HIV) envelope and core proteins in CNS tissues of patients with the acquired immune deficiency syndrome (AIDS). Acta Neuropathol 1990; 79: 611–619
   PubMed Web of Science ®Google Scholar
• Cheng-Mayer, Quiroga, Tung, Dina, Levy. Viral determinants of human immunodeficiency virus type 1 T-cell or macrophage tropism, cytopathogenicity and CD4 antigen modulation. J Virology 1990; 64: 4390–4398
   PubMedGoogle Scholar
• Fouchier AM, Brouwer, Koostra, Huisman, Schuitemaker. HIV-1 macrophage tropism is determined at multiple levels of the viral replication cycle. J Clin Invest 1994; 94: 1806–1814
   Google Scholar
• Giulian, Vaca, Noonan. Secretion of neurotoxins by mononuclear phagocytes infected with HIV-1. Science 1990; 250: 1593–1596
   PubMed Web of Science ®Google Scholar
• Glass, Wesselingh, Selnes, McArthur. Clinical-neuropathologic correlation in HIV-associated dementia. Neurology 1993; 43: 2230–2237
   PubMedGoogle Scholar
• Heyes, Markey. Quantification of quinolinic acid in rat brain, whole blood and plasma by gas chromatography and negative chemical ionisation mass spectrometry: effects of systemic L-tryptophan administration on brain and blood quinolinic acid concentrations. Anal Biochem 1988; 174: 349–359
   Google Scholar
• Heyes, Brew, Martin, Price, Salazaar, Sidtis, Tergey, Mouradian, Sadler, Keilp, Rubinow, Markey. Increased cerebrospinal fluid concentrations of the excitotoxin quinolinic acid in human immunodeficiency virus infection and AIDS dementia complex. Ann Neurol 1991; 29: 202–209
   PubMed Web of Science ®Google Scholar
• Heyes, Saito, Markey. Human macrophages convert L-tryptophan to the neurotoxin quinolinic acid. Biochem J 1992; 283: 633–635
   PubMed Web of Science ®Google Scholar
• Jordan, Watkins, Kufta, Dubois-Dalcq M. Infection of brain microglial cells by human immunodeficiency virus type 1 is CD4 dependent. J Virol 1991; 65: 736–742
   Google Scholar
• Karber. Beitrag zur kellektiven behaadlung pharmakologischer reihenvorsucho. Arch Exp Pathol Pharmakol 1931; 162: 480–483
   Google Scholar
• Ketzler, Weis, Huag, Budka. Loss of neurons in the frontal cortex in AIDS brains. Acta Neuropathol 1990; 80: 92–94
   PubMed Web of Science ®Google Scholar
• Kim, Choi. Quinolinate neurotoxicity in cortical cell culture. Neurosci 1987; 25: 423–432
   Google Scholar
• Koyanagi, Miles, Mitsuyasu, Merrill, Vinters, Chen SY. Dual infection of the central nervous system by AIDS virsuses with distinct cellular tropisms. Science 1987; 236: 819–822
   PubMed Web of Science ®Google Scholar
• Michaels, Price, Rosenblum. Microglia in the human immunodeficiency virus encephalitis of acquired immune deficiency syndrome: proliferation, infection and fusion. Acta Neuropathol 1988; 76: 373–379
   PubMed Web of Science ®Google Scholar
• Price, Brew. The AIDS dementia complex. J Infect Dis 1988; 158: 1079–1083
   PubMed Web of Science ®Google Scholar
• Price. Management of AIDS dementia complex and HIV-1 infection of the nervous system. AIDS 1995, suppl A: S221–S236
   Google Scholar
• Pulliam, Herndier, Tang, McGrath. Human immunodeficiency virus-infected macrophages produce soluble factors that cause histological and neurochemical alterations in cultured human brains. J Clin Invest 1991; 87: 503–512
   PubMedGoogle Scholar
• Schwarcz, Whetsell, Jr, Mangano. Quinolinic acid: an endogenous metabolite that produces axon-sparing lesions in rat brain. Science 1983; 219: 316–318
   PubMed Web of Science ®Google Scholar
• Whetsell, Jr, Schwarcz. Prolonged exposure to submicromolar concentrations of quinolinic acid cause excitotoxic damage in organotypic cultures of rat corticostriatal system. Neurosci Lett 1989; 97: 271–275
   Google Scholar
• Wiley, Masliah, Morey, Lemere, De Teresa, Grafe, Hansen, Terry. Neocortical damage during HIV infection. Ann Neurol 1991; 29: 651–657
   PubMed Web of Science ®Google Scholar
• York-Higgins, Chen-Mayer, Cauer, Levy, Dina. Human immunodeficiency virus type 1 cellular host range, replication and cytopathogenicity are linked to the envelope region of the viral genome. J Virol 1990; 64: 4016–4020
   Google Scholar