Deficits in discriminated learning remain despite clearance of long-term persistent viral infection in mice

References

• Beers DR, Henkel J, Kesner RP, Stroop WG. Spatial recognition memory deficits without notable CNS pathology in rats following herpes simplex encephalitis. J Neurological Sci 1995; 131: 119–127
   PubMed Web of Science ®Google Scholar
• Beninger RJ, Jhamandas K, Boegman RJ, El-Defrawy SR. Effects of scopolamine and unilateral lesions of the basal forebrain on T-maze spatial discrimination and alternation in rats. Pharm Biochem Behav 1986; 24: 1353–1360
   PubMedGoogle Scholar
• Borrow P, Oldstone MBA. Lymphocytic choriomeningitis virus. Viral Pathogenesis, N Nathanson. Lippincott-Raven Publishers, Philadelphia 1997; 593–627
   Google Scholar
• de la Torre JC, Mallory M, Brot M, Gold L, Koob G, Oldstone MBA, Masliah E. Viral persistence in neurons alters synaptic plasticity and cognitive functions without destruction of brain cells. Virology 1996; 220: 508–515
   Google Scholar
• Dittrich W, Bode L, Ludwig H, Kao J, Schneider K. Learning deficiencies in borna disease virus-infected but clinically healthy rats. Biological Psychiatry 1989; 26: 818–828
   Google Scholar
• Fazakerley JK, Southern P, Bloom FE, Buchmeier MJ. High resolution in situ hybridization to determine the cellular distribution of lymphocytic choriomeningitis virus RNA in the tissues of persistently infected mice: Relevance to arenavirus disease and mechanisms of viral persistance. J General Virology 1991; 72: 1611–1625
   Google Scholar
• Feeser HR, Raskin LA. Effects of neonatal dopamine depletion on spatial ability during ontogeny. Behav Neurosci 1987; 101: 812–818
   Google Scholar
• Gold LH, Brot MD, Polis I, Schroeder R, Tishon A, de la Torre JC, Oldstone MBA, Koob GF. Behavioral effects of persistent lymphocytic choriomeningitis virus infection in mice. Behav Neural Biol 1994; 62: 100–109
   Google Scholar
• Ha J-H, Sei Y, Basile AS. Striatal met-enkephalin and substance P levels are decreased in mice infected with the LP-BM5 murine leukemia virus. J Neurochem 1995; 64: 1896–1898
   Google Scholar
• Heyser CJ, Masliah E, Samimi A, Campbell IL, Gold LH. Progressive decline in avoidance learning paralleled by inflammatory neurodegeneration in transgenic mice expressing interleukin 6 in the brain. Proc Natl Acad Sci 1997; 94: 1500–1505
   PubMed Web of Science ®Google Scholar
• Hotchin J. The biology of lymphocytic choriomeningitis infection: virus-induced immune disease. Cold Spring Harbor Symp Quant Biol 1962; 27: 479–499
   PubMedGoogle Scholar
• Hotchin J, Seegal R. Virus-induced behavioral alteration of mice. Science 1977; 196: 671–674
   PubMed Web of Science ®Google Scholar
• Hotchin J, Seegal R. Alterations in behavior resulting from persistent lymphocytic choriomeningitis virus infection. Birth Defects: Original Article Series. XIV. The National Foundation. 1978; 171–178
   Google Scholar
• McFarland DJ, Hotchin J. Host genetics and the behavioral sequelae to herpes encephalitis in mice. Physiology and Behavior 1983; 30: 881–884
   Google Scholar
• Mohammed AKH, Maehlen J, Magnusson O, Fonnum F, Kristensson K. Persistent changes in behavior and brain serotonin during ageing in rats subjected to infant nasal virus infection. Neurobiology of Aging 1991; 13: 83–87
   Google Scholar
• Mohammed AKH, Magnusson O, Maehlen J, Fonnum F, Norrby E, Schultzberg M, Kristensson K. Behavioural deficits and serotonin depletion in adult rats after transient infant nasal viral infection. Neuroscience 1990; 35: 355–363
   Google Scholar
• Oldstone MBA, Ahmed R, Buchmeier MJ, Blount P, Tishon A. Perturbation of differentiated functions during viral infection in vivo. I. Relationship of lymphocytic choriomeningitis virus and host strains to growth hormone deficiency. Virology 1985; 142: 158–174
   Google Scholar
• Oldstone MBA, Blount P, Southern PJ, Lampert PW. Cytoimmunotherapy for persistent virus infection reveals a unique clearance pattern from the central nervous system. Nature 1986; 321: 239–243
   PubMed Web of Science ®Google Scholar
• Oldstone MBA, Holmstoen J, Welsh RM, Jr. Alterations of acetylcholine enzymes in neuroblastoma cells persistently infected with lymphocytic choriomeningitis virus. J Cellular Physiol 1977; 91: 459–472
   PubMed Web of Science ®Google Scholar
• Peters CJ, Buchmeier M, Rollin PE, Ksiazek TG. renaviruses. Fields Virology, BN Fields, DM Knipe, PM Howley, et al. Lippincott-Raven Publishers, Philadelphia 1996a; 1521–1551
   Google Scholar
• Rail GF, Mucke L, Oldstone MBA. Consequences of cytotoxic T lymphocyte interaction with major histocompatibility complex class I-expressing neurons in vivo. J Exp Med 1995; 182: 1201–1212
   Google Scholar
• Rodriguez M, Buchmeier MJ, Oldstone MBA, Lampert PW. Ultrastructural localization of viral antigens in the CNS of mice persistently infected with lymphocytic choriomeningitis virus (LCMV). Am J Pathol 1983; 110: 95–100
   Google Scholar
• Sei Y, Arora PK, Skolnick P, Paul IA. Spatial learning impairment in a murine model of AIDS. FASEB J 1992; 6: 3008–3013
   Google Scholar
• Sei Y, Paul IA, Saito K, Layar R, Harltey JW, Morse HC, Skolnick P, Heyes MP. Quinolinic: acid levels in a murine retrovirus-induced immunodeficiency syndrome. J Neurochem 1996; 66: 296–302
   PubMed Web of Science ®Google Scholar
• Tishon A, Eddleston M, de la Torre JC, Oldstone MBA. Cytotoxic T lymphocytes cleanse viral gene products from individually infected neurons and lymphocytes in mice persistently infected with lymphocytic choriomeningitis virus. Virology 1993; 197: 463–467
   Google Scholar
• Tishon A, Lewicki H, Rail G, von Herrath M, Oldstone MBA. An essential role for type 1 interferon-γ in terminating persistent viral infection. Virology 1995; 212: 244–250
   PubMedGoogle Scholar
• Weinberger DR, Lipska BK. Cortical maldevelopment, anti-psychotic drugs and schizophrenia: a search for common ground. Schizophrenia Res 1995; 16: 87–110
   PubMed Web of Science ®Google Scholar
• Yayou K, Takeda M, Tsubone H, Sugano S, Doi K. The disturbance of water-maze task performance in mice with EMC-D virus infection. J Vet Med Sci 1993; 55: 341–342
   Google Scholar
• Zinkernagel R, Callahan G, Althage A, Cooper S, Klein P, Klein J. On the thymus in the differentiation of 'H-2 self-recognition' by T cells: Evidence for dual recognition?. J Exp Med 1978; 147: 882–896
   PubMed Web of Science ®Google Scholar