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Original Article

The Effect of Human Herpesvirus-6 (HHV-6) on Cultured Human Neural Cells: Oligodendrocytes and Microglia

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Pages 486-494 | Received 21 Jan 1998, Accepted 09 Mar 1998, Published online: 05 Aug 2009

References

  • Ablashi D. V., Salahuddin S. Z., Josephs S. F., Iman F., Lusso P., Gallo R. C. HBLV (or HHV-6) in human cell lines. Nature 1987; 329: 207
  • Albright A. V., Strizki J., Harouse J. M., Lavi E., O'Connor M., Gonzalez-Scarano F. HIV-1 infection of cultured human adult oligodendrocytes. Virology 1996; 217: 211–219
  • Asano Y., Yoshikawa T., Kajita Y., Ogura R., Suga S., Yazaki T., Nakashima T., Yamada A., Kurata T. Fatal encephalitis/encephalopathy in primary human herpesvirus-6 infection. Arch Dis Child 1992; 67: 1484–1485
  • Biberfeld P., Kramarsky B., Salahuddin S. Z., Gallo R. C. Ultrastructural characterization of a new human B lymphotropic DNA virus (human herpesvirus 6) isolated from patients with lympho-proliferative disease. J Natl Cancer Institute 1987; 79: 933–941
  • Carrigan D. R., Harrington D., Knox K. K. Subacute leukoencephalitis caused by CNS infection with human herpesvirus-6 manifesting as acute multiple sclerosis. Neurology 1996; 47: 145–148
  • Caserta M. T., Hall C. B., Schnabel K., McLntyre K., Long C., Costanzo M., Dewhurst S., Insel R., Epstein L. G. Neuroinvasion and persistence of human herpesvirus 6 in children. J Infect Dis 1994; 170: 1586–1589
  • Challoner P. B., Smith K. T., Parker I. D., MacLeod D. L., Coulter S. N., Rose T. M., Schultz E. R., Bennett J. L., Garber R. L., Chang M., Schad P. A., Stewart P. M., Nowinski R. C., Brown I. P., Burmer G. C. Plaque-associated expression of human herpesvirus 6 in multiple sclerosis. Proc Natl Acad Sci 1995; 92: 7440–7444
  • Cook S. D., Rohowsky-Kochan C., Bansil S. Evidence for a viral etiology of multiple sclerosis. Handbook of multiple sclerosis, S. D. Cook. Marcel Dekkerpp, New York, 97–118
  • Drobyski W. R., Knox K. K., Majewski D., Carrigan D. R. Brief report: Fatal encephalitis due to variant B human herpesvirus-6 infection in a bone marrow-transplant recipient. N Engl J Med 1994; 19: 1356–1360
  • Gompels U. A., Nicholas J., Lawrence G., Jones M., Thomson B. J., Martin MED, Efstathiou S., Craxton M., Macaulay H. A. The DNA sequence of human herpesvirus-6: Structure, coding content, and genome evolution. Virology 1995; 209: 29–51
  • Hall C. B., Longe C. E., Schnabel K. C., Caserta M. T., McLntyre K. M., Costanzo M. A., Knott A., Dewhurst S., Insel R. A., Epstein L. G. Human herpesvirus-6 infection in children: a prospective study of complications and reactivation. N Engl J Med 1994; 331: 432–438
  • He J., McCarthy M., Zhou Y., Chandran B., Wood C. Infection of primary human fetal astrocytes by human herpesvirus 6. J Virology 1996; 70: 1296–1300
  • Huang L-M, Lee C-Y, Lee P-I, Chen J. M., Wang P. J. Meningitis caused by human herpesvirus-6. Arch Dis Child 1991; 66: 1443–1444
  • Inoue N., Dambaugh T. R., Pellet P. E. Infectious agents and disease 1994; 2: 343–360
  • Irving W. L., Chang J., Raymond D. R., Dunstan R., Grattan-Smith P., Cunningham A. L. Roseola infantum and other syndromes associated with acute HHV-6 infection. Arch Dis Child 1990; 65: 1297–1300
  • Ishiguro N., Yamada S., Takahashi T., Takahashi Y., Togashi T., Okuno T., Yamanishi K. Meningoencephalitis associated with HHV-6 related ex-anthem subitum. Acta Paediatr Scand 1990; 79: 987–989
  • Knox K. K., Carrigan D. R. Active human herpesvirus (HHV-6) infection of the central nervous system in patients with AIDS. J Acquired Immune Deficiency Syndromes and Human Retrovirology 1995; 9: 69–73
  • Knox K. K., Harrington D. P., Carrigan D. R. Fulminant human herpesvirus six encephalitis in a human immunodeficiency virus-infected infant. J Med Virology 1995; 45: 288–292
  • Kondo K., Nagafuji H., Hata A., Tomomori C., Yamanishi K. Association of human herpesvirus 6 infection of the central nervous system with recurrence of febrile convulsions. J Inf Dis 1993; 167: 1197–1200
  • Liedtke W., Malessa R., Faustmann P. M., Eis-Hubinger A-M. Human herpesvirus 6 polymerase chain reaction findings in human immunodeficiency virus associated neurological disease and multiple sclerosis. J Neuro Virology 1995; 1: 253–258
  • Luppi M., Barozzi P., Maiorana A., Marasca R., Torelli G. Human herpesvirus 6 infection in normal human brain tissue. J Inf Dis 1994; 169: 943–944
  • Lusso P., Gallo R. C., DeRocco S. E., Markham P. D. CD4 is not the membrane receptor for HHV-6. Lancet 1989; 1: 730
  • Mackenzie I.R.A., Carrigan D. R., Wiley C. A. Chronic myelopathy associated with human herpesvirus-6. Neurology 1995; 45: 2015–2017
  • McCullers J. A., Lakeman F. D., Whitley R. J. Human herpesvirus 6 is associated with focal encephalitis. Clin Inf Dis 1995; 21: 571–576
  • Moore P. S., Gao S-J, Dominguez G., Cesarman E., Lungu O., Knowles D. M., Garber R., Pellett P. E., McGeoch D. J., Chang Y. Primary characterization of a herpesvirus agent associated with Kaposi's sarcoma. J Virol 1996; 70: 549–558
  • Moschettini D., Balestri P., Fois A., Valensin P. E. Acute encephalitis due to human herpesvirus 6. Clin Inf Dis 1996; 23: 397–398
  • Nicholas J., Ruvolo V. R., Burns W. H., Sanford G., Wan X., Ciufo D., Hendrickson S. B., Guo H-G, Hayward G. S., Reitz M. S. Kaposi's sarcoma-associated human herpesvirus-8 encodes homologues of macrophage inflammatory protein-1 and interleukin-6. Nature Med 1997; 3: 287–292
  • Pellet P., Black J. B. Human Herpesvirus 6. Fields Virology, B. N. Fields, D. M. Knipe, PM Howley. Lippincott-Raven, Philadelphia, 2587–2608
  • Pellet P. E., Black J. B., Yamamoto M. Human herpesvirus 6: the virus and the search for its role as a human pathogen. Adv Vir Res 1992; 41: 1–52
  • Peters A., Palay S. L., Webster H. The fine structure of the nervous system. The cells and their processes, Harper. Row Publ, New York 1970; 120–128
  • Pleasure S. J., Page C., Lee VM-Y. Pure, postmitotic, polarized human neurons derived from NTera 2 cells provide a system for expressing exogenous proteins in terminally differentiated neurons. J Neuroscience 1992; 12: 1802–1815
  • Ranscht B., Clapshaw P. A., Price J., Noble M, Seifer W. Development of oligodendrocytes and Schwann cells studied with a monoclonal antibody against galactocerebroside. Proc Natl Acad Sci USA 1982; 79: 2709–2713
  • Saito Y., Sharer L. R., Dewhurst S., Blumberg B. M., Hall C. B., Epstein L. G. Cellular localization of human herpesvirus-6 in the brains of children with AIDS encephalopathy. J NeuroVirology 1995; 1: 30–39
  • Salahuddin S. Z., Ablashi D. V., Markham P. D., Josephs S. F., Sturzenegger S., Kaplan M., Halligan G., Biberfeld P., Wong-Staal F., Kramarsky B., Gallo R. C. Isolation of a new virus, HBLV, in patients with lymphoproli-ferative disorders. Science 1986; 234: 596–601
  • Secchiero P., Carrigan D. R., Asano Y., Benedetti L., Crowley R. W., Komaroff A. L., Gallo R. C., Lusso P. Detection of human herpesvirus 6 in plasma of children with primary infection and immunosup-pressed patients by polymerase chain reaction. J Inf Dis 1995; 171: 273–280
  • Soldan S. S., Berti R., Salem N., Secchiero P., Flamand L., Calabresi P., Brennan M. B., Maloni H. W., McFarland H. F., Lin H., Patnaik M., Jacobson S. Association of human herpes virus 6 (HHV-6) with multiple sclerosis: increased IgM response to HHV-6 early antigen and detection of serum HHV-6 DNA. Nature Medicine 1997; 3: 1994–1997
  • Suga S., Yoshikawa T., Asano Y., Kozawa T., Nakashima T., Kobayashi I., Yazaki T., Yamamoto H., Kajita Y., Ozaki T., Nishimura Y., Yamanaka T., Yamada A., Imanishi J. Clinical and virological analyses of 21 infants with exanthen subitum (roseola infantum) and central nervous system complications. Ann Neurol 1993; 33: 597–603
  • Strizki J. M., Albright A. V., Sheng H., O'Connor M., Perrin L., Gonzalez-Scarano F. Infection of primary human microglia and monocyte-derived macrophages with human immunodeficiency virus type 1 isolates: Evidence of differential tropism. J Virol 1996; 70: 7654–7662
  • White J., Matlin K., Helenius A. Cell fusion by Semiliki Forest, Influenza, and Vesicular Stomatitits Viruses. J Cell Biol 1981; 89: 674–679
  • Wilborn F., Schmidt C. A., Brinkmann V., Jendroska K., Oettle H., Siegert W. A potential role for human herpesvirus type 6 in nervous system disease. J Neuroimmunol 1994; 49: 213–214
  • Yamanishi K., Okuno T., Shiraki K., Kondo T., Nagafuji H., Kato T., Okuno T., Kurata T. Identification of human herpesvirus-6 as a causal agent for exanthema subitum. Lancet 1988; 1: 1065–1067
  • Yong V. W., Antel J. P. Culture of glial cells from human brain biopsies. Protocols for neural cell culture, S. Fedoroff, A. Richardson. Humana Pres, Totowa, NJ 1992; 81–96
  • Yoshikawa T., Nakashima T., Suga S., Asano Y., Yazaki T., Kimura H., Morishima T., Kondo K., Yamanishi K. Human herpesvirus-6 DNA in cerebrospinal fluid of a child with exanthem subitum and meningoencephalitis. Pediatrics 1992; 89: 888–890

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