Chemokine expression in GKO mice (lacking interferon-gamma) with experimental autoimmune encephalomyelitis

References

• Asensio V C, Campbell I L. Chemokine gene expression in the brains of mice with lymphocytic choriomeningitis. J Virol 1997; 71: 7832–7840
   PubMed Web of Science ®Google Scholar
• Billiau A, Heremans H, Vandekerckhove F, Dijkmans R, Sobis H, Meulepas E, Carton H. Enhancement of experimental allergic encephalomyelitis in mice by antibodies against IFN-gamma. J Immunol 1988; 140: 1506–1510
   PubMed Web of Science ®Google Scholar
• Cheifetz S, Moscarello M, Deber C. NMR investigation of the charge isomers of bovine myelin basic protein. Arch Biochem Biophys 1984; 233: 151–160
   Google Scholar
• Dalton D, Pitts-Meek S, Keshav S, Figari I, Bradley A.TA S. Multiple defects of immune cell function in mice with disrupted interferon-gamma gene. Science 1993; 259: 1739–1742
   PubMed Web of Science ®Google Scholar
• Duong T, Finkelman F, Singh B, Strejan G. Effect of anti-interferon-gamma monoclonal antibody treatment on the development of experimental allergic encephalomyelitis in resistant mouse strains. J Neu-roimmunol 1994; 53: 101–107
   Google Scholar
• Ferber I, Brocke S, Taylor-Edwards C, Ridgway W, Dinisco C, Steinman L, Dalton D, Fathman C. Mice with a disrupted IFN-gamma gene are susceptible to the induction of experimental autoimmune encephalomyelitis. J Immunol 1996; 156: 5–7
   PubMed Web of Science ®Google Scholar
• Glabinski A, Tani M, Aras S, Stoler M, Tuohy V, Ransohoff R. Regulation and function of central nervous system chemokines. International J Dev Neurosci 1995a; 13: 153–165
   PubMedGoogle Scholar
• Glabinski A, Tani M, Tuohy V K, Tuthill R, Ransohoff R M. Central nervous system chemokine gene expression follows leukocyte entry in acute murine experimental autoimmune encephalomyelitis. Brain Behav Immun 1995b; 9: 315–330
   PubMed Web of Science ®Google Scholar
• Glabinski A, Tani M, Strieter R, Tuohy V, Ransohoff R. Synchronous synthesis of α- and β-chemokines by cells of diverse lineage in the central nervous system of mice with relapses of experimental autoimmune encephalomyelitis. Am J Pathol 1997; 150: 617–630
   PubMed Web of Science ®Google Scholar
• Glabinski A R, Tani M, Balasingam V, Yong V W, Ransohoff R M. Chemokine monocyte chemoattractant protein-1 (MCP-1) is expressed by astrocytes after mechanical injury to the brain. J Immunol 1996; 156: 4363–4368
   Google Scholar
• Goes N, Sims T, Urmson T, Vincent D, Ramassar V, Holloran P. Disrupted MHC regulation in the IFN-gamma knockout mouse. Evidence for three states of MHC expression with distinct roles for IFN-gamma. J Immunol 1995; 155: 4559–4566
   Google Scholar
• Gourmala N G, Buttini M, Limonta S, Sauter A, Boddeke H W. Differential and time-dependent expression of monocyte chemoattractant protein-1 mRNA by astrocytes and macrophages in rat brain: effects of ischemia and peripheral lipopolysaccharide administration. J Neuroimmunol 1997; 74: 35–44
   PubMed Web of Science ®Google Scholar
• Hartung H, Schafer B, van der Meide P, Fierz W, Heininger K, Toyka K. The role of interferon-gamma in the pathogenesis of experimental autoimmune disease of the peripheral nervous svstem. Ann Neurol 1990; 27: 247–257
   PubMed Web of Science ®Google Scholar
• Hofman F, von Hanwehr R, Dinarello C, Mizel S, Hinton D, Merrill J. Immunoregulatory molecules and IL-2 receptors identified in multiple sclerosis brain. J Immunol 1986; 136: 3239–3247
   PubMed Web of Science ®Google Scholar
• Hofman F M, Hinton D R, Johnson K, Merrill J E. Tumor necrosis factor identified in multiple sclerosis brain. J Exp Med 1989; 170: 607–612
   PubMed Web of Science ®Google Scholar
• Horwitz M, Evans C, McGavern D, Rodriguez M, Oldstone M. Primary demyelination in transgenic mice expressing interferon-gamma. Nature Med 1997; 3: 1037–1041
   PubMed Web of Science ®Google Scholar
• Karpus W J, Lukacs N W, McRae B L, Strieter R M, Kunkel S L, Miller S D. An important role for the chemokine macrophage inflammatory protein-1α in the pathogenesis of the T cell-mediated autoimmune disease, experimental autoimmune encephalomyelitis. J Immunol 1995; 155: 5003–5010
   PubMed Web of Science ®Google Scholar
• Kim J S, Gautam S C, Chopp M, Zaloga C, Jones M L, Ward P A, Welch K M A. Expression of monocyte chemoattractant protein-1 and macrophage inflammatory protein-1 after focal cerebral ischemia in the rat. J Neumimmunol 1995; 56: 127–134
   PubMed Web of Science ®Google Scholar
• Krakowski M, Owens T. Interferon-gamma confers resistance to experimental allergic encephalomyelitis. Eur J Immunol 1996; 26: 1641–1646
   PubMed Web of Science ®Google Scholar
• Merrill J, Kono D, Clayton J, Ando D, Hinton D, Hofman F. Inflammatory leukocytes and cytokines in the peptide-induced disease of experimental allergic encephalomyelitis in SJL and B10.PL mice. Proc Natl Acad Sci USA 1992; 89: 574–578
   PubMed Web of Science ®Google Scholar
• Narumi S, Wyner L, Stoler M, Tannenbaum C, Hamilton T. Tissue specific expression of murine IP-10 mRNA following systemic treatment with interferon-γ. J Leukocyte Biol 1992; 52: 27–33
   PubMed Web of Science ®Google Scholar
• Ohmori Y, Hamilton T A. IFN-gamma selectivity inhibits lipopolysaccharide-inducible JE/monocyte chemoattractant protein-1 and KC/GRO/melanoma growth-stimulating activity gene expression in mouse peritoneal macrophages. J Immunol 1994; 153: 2204–2212
   PubMedGoogle Scholar
• Panitch H S, Hirsch R L, Haley A S, Johnson K P. Exacerbations of multiple sclerosis in patients treated with gamma interferon. Lancet 1987a; 1: 893–895
   PubMed Web of Science ®Google Scholar
• Panitch H S, Hirsch R L, Schindler J, Johnson K P. Treatment of multiple sclerosis with gamma interferon: exacerbations associated with activation of the immune system. Neurology 1987b; 37: 1097–1102
   PubMed Web of Science ®Google Scholar
• Ping D, Jones P L, Boss J M. TNF regulates the in vivo occupancy of both distal and proximal regulatory regions of the MCP-1/JE gene. Immunity 1996; 4: 455–469
   PubMed Web of Science ®Google Scholar
• Ransohoff R, Tani M, Glabinski A, Chernosky A, Krivacic K, Peterson J, Chien H, Trapp B. Chemokines and chemokine receptors in model neurological pathologies: molecular and immunocyto-chemical approaches. Methods Enzymol 1997; 287: 319–348
   Google Scholar
• Ransohoff R M, Hamilton T A, Tani M, Stoler M H, Shick H E, Major J A, Estes M L, Thomas D M, Tuohy V K. Astrocyte expression of mRNA encoding cytokines IP-10 and JE/MCP-1 in experimental autoimmune encephalomyelitis. FASEB J 1993; 7: 592–602
   PubMed Web of Science ®Google Scholar
• Renno T, Krakowski M, Piccirillo C, Lin J Y, Owens T. TNF-alpha expression by resident microglia and infiltrating leukocytes in the central nervous system of mice with experimental allergic encephalomyelitis. Regulation by Th1 cytokines. J Immunol 1995; 154: 944–953
   Google Scholar
• Romano M, Sironi M, Toniatti C, Polentarutti N, Fruscella P, Ghezzi P, Faggioni R, Luini W, van Hinsbergh V, Sozzani S, Bussolino F, Poli V, Ciliberto G, Mantovani A. Role of IL-6 and its soluble receptor in induction of chemokines and leukocyte recruitment. Immunity 1997; 6: 315–325
   PubMed Web of Science ®Google Scholar
• Selmaj K, Raine C S, Canella B, Brosnan C F. Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions. J Clin Invest 1991; 87: 949–954
   PubMed Web of Science ®Google Scholar
• Sethna M, Lampson L. Immune modulation within the brain: recruitment of inflammatory cells and increased major histocompatibility antigen expression following intracerebral injection of interferon-gamma. J Neuroimmunol 1991; 34: 121–132
   PubMed Web of Science ®Google Scholar
• Sharief M, Hentges R. Association between tumor necrosis factor-alpha and disease progression in patients with multiple sclerosis. N Engl J Med 1991; 325: 467–471
   PubMed Web of Science ®Google Scholar
• Simmons R D, Willenborg D O. Direct injection of cytokines into the spinal cord causes autoimmune encephalomyelitis-like inflammation. J Neuro Sci 1990; 100: 37–42
   PubMed Web of Science ®Google Scholar
• Tani M, Glabinski A R, Tuohy V K, Stoler M H, Estes M L, Ransohoff R M. In situ hybridization analysis of glial fibrillary acidic protein mRNA reveals evidence of biphasic astrocyte activation during acute experimental autoimmune encephalomyelitis. Am J Pathol 1996; 148: 889–896
   PubMed Web of Science ®Google Scholar
• Voorthuis J, Uitdehaag B, De Groot C, Goede P, van der Meide P, Dijkstra C. Suppression of experimental allergic encephalomyelitis by intraventricular administration of interferon-gamma in Lewis rats. Clin Exp Immunol 1990; 81: 183–188
   PubMed Web of Science ®Google Scholar
• Wojcik W J, Swoveland P, Zhang X, Vanguri P. Chronic intrathecal infusion of phosphorothioate or phosphodiester antisense oligonucleotides against cytokine responsive gene-2/IP-10 in experimental allergic encephalomyelitis of Lewis rat. J Pharmacol Exp Ther 1996; 278: 404–410
   PubMedGoogle Scholar
• Zhou L, Miller R. Antibody-mediated oligodendrocyte cell death requires an astrocytederived cosignal. J Neurosci Res 1998; 52: 137–148
   Google Scholar