Effects of different doses of soy isoflavones on bone tissue of ovariectomized rats

References

• Holroyd C, Cooper C, Dennison E. Epidemiology of osteoporosis. Best Pract Res Clin Endocrinol Metab 2008;22:5: 671–85
   PubMed Web of Science ®Google Scholar
• Pinheiro Mde M, Eis SR. Epidemiology of osteoporotic fractures in Brazil: what we have and what we need. Arq Bras Endocrinol Metabol 2010;54:164–70
   PubMed Web of Science ®Google Scholar
• Andersen SJ. Osteoporosis in the older woman. Clin Obstet Gynecol 2007;50:752–66
   PubMed Web of Science ®Google Scholar
• Cooper C, Campion G, Melton LJ 3rd.Hip fractures in the elderly: a world-wide projection. Osteoporos Int 1992;2285–9
   Web of Science ®Google Scholar
• Walker-Bone K, Dennison E, Cooper C. Epidemiology of osteoporosis. Rheum Dis Clin NA 2001;27:1–18
   PubMed Web of Science ®Google Scholar
• Stevenson JC. Long-term effects of hormone replacement therapy. Lancet 2003;361:253–4
   PubMed Web of Science ®Google Scholar
• Rossouw JE, Anderson GL, Prentice RL, et al. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women's Health Initiative randomized controlled trial. JAMA 2002;288:321–33
   PubMed Web of Science ®Google Scholar
• Kerlikowske K, Cook AJ, Buist DS, et al. Breast cancer risk by breast density, menopause, and postmenopausal hormone therapy use. J Clin Oncol 2010;28:3830–7
   PubMed Web of Science ®Google Scholar
• Santen RJ, Allred DC, Ardoin SP, et al. Postmenopausal hormone therapy: an Endocrine Society scientific statement. J Clin Endocrinol Metab 2010;95:1–66
   PubMed Web of Science ®Google Scholar
• Alekel DL, Germain AS, Peterson CT, et al. Isoflavone-rich soy protein isolate attenuates bone loss in the lumbar spine of perimenopausal women. Am J Clin Nutr 2000;72:844–52
   PubMed Web of Science ®Google Scholar
• Molla MD, Hidalgo-Mora JJ, Soteras MG. Phytotherapy as alternative to hormone replacement therapy. Front Biosci 2011; 31:191–204
   Google Scholar
• Setchell KD, Cassidy A. Dietary isoflavones: biological effects and relevance to human health. J Nutr 1999;129:758–67
   PubMed Web of Science ®Google Scholar
• Unfer V, Casini ML, Costabile L, et al. Endometrial effects of long-term treatment with phytoestrogens: a randomized, double-blind, placebo-controlled study. Fertil Steril 2004;82:145–8
   PubMed Web of Science ®Google Scholar
• Oseni T, Patel R, Pyle J, et al. Selective estrogen receptor modulators and phytoestrogens. Planta Med 2008;74:1656–65
   PubMed Web of Science ®Google Scholar
• Xiao CW. Health effects of soy protein and isoflavones in humans. J Nutr 2008;138:1244–9
   PubMed Web of Science ®Google Scholar
• Ferrari A. Soy extract phytoestrogens with high dose of isoflavones for menopausal symptoms. J Obstet Gynaecol Res 2009;35:1083–90
   PubMed Web of Science ®Google Scholar
• Lydeking-Olsen E, Beck-Jensen JE, et al. Soymilk or progesterone for prevention of bone loss: a 2 year randomized, placebo- controlled trial. Eur J Nutr 2004;43:246–57
   PubMed Web of Science ®Google Scholar
• Huang HY, Yang HP, Yang HT, et al. One-year soy isoflavones supplementation prevents early postmenopausal bone loss but without a dose dependent effect. J Nutr Biochem 2006;17:509–17
   PubMed Web of Science ®Google Scholar
• Newton KM, LaCroix AZ, Levy L, et al. Soy protein and bone mineral density in older men and women: a randomized trial. Maturitas 2006;55:270–7
   PubMed Web of Science ®Google Scholar
• Arjmandi BH, Lucas EA, Khalil DA, et al. One year soy protein supplementation has positive effects on bone formation markers but not bone density in postmenopausal women. Nutr J 2005;4:8
   PubMed Web of Science ®Google Scholar
• Wu J, Oka J, Tabata I, Higuchi M, et al. Effects of isoflavone and exercise on BMD and fat mass in postmenopausal Japanese women: a 1-year randomized placebo-controlled trial. J Bone Miner Res 2006;21:780–9
   PubMed Web of Science ®Google Scholar
• Brink E, Coxam V, Robins S, et al. Long-term consumption of isoflavone-enriched foods does not affect bone mineral density, bone metabolism, or hormonal status in early postmenopausal women: a randomized, double-blind, placebo controlled study. Am J Clin Nutr 2008;87:761–70
   PubMed Web of Science ®Google Scholar
• Setchell KD. Soy isoflavones – benefits and risks from nature’s selective estrogen receptor modulators (SERMs). J Am Coll Nutr 2001;20:354–62
   PubMed Web of Science ®Google Scholar
• Fonseca D, Ward WE. Daidzein together with high calcium preserve bone mass and biomechanical strength at multiple sites in ovariectomized mice. Bone 2004;35:489–97
   PubMed Web of Science ®Google Scholar
• Ward WE, Fonseca D. Soy isoflavones and fatty acids: effects on bone tissue postovariectomy in mice. Mol Nutr Food Res 2007; 51:824–31
   PubMed Web of Science ®Google Scholar
• Mei J, Yeung SS, Kung AW. High dietary phytoestrogen intake is associated with higher bone mineral density in postmenopausal but not premenopausal women. J Clin Endocrinol Metab 2001;86:5217–21
   PubMed Web of Science ®Google Scholar
• Kreijkamp-Kaspers S, Kok L, Grobbee DE, et al. Effect of soy protein containing isoflavones on cognitive function, bone mineral density, and plasma lipids in postmenopausal women: a randomized controlled trial. JAMA 2004;292:65–74
   PubMed Web of Science ®Google Scholar
• Levis S, Strickman-Stein N, Ganjei-Azar P, et al. Soy isoflavones in the prevention of menopausal bone loss and menopausal symptoms: a randomized, double-blind trial. Arch Intern Med 2011;171:1363–9
   PubMed Web of Science ®Google Scholar
• Friso A, Tomanin R, Salvalaio M, et al. Genistein reduces glycosaminoglycan levels in a mouse model of mucopolysaccharidosis type II. Br J Pharmacol 2010;159:1082–91
   PubMed Web of Science ®Google Scholar
• Nikitovic D, Tsatsakis AM, Karamanos NK, et al. The effects of genistein on the synthesis and distribution of glycosaminoglycans/proteoglycans by two osteosarcoma cell lines depends on tyrosine kinase and the estrogen receptor density. Anticancer Res 2003;23:459–64
   PubMed Web of Science ®Google Scholar
• Patriarca MT, Barbosa de Moraes AR, Nader HB, et al. Hyaluronic acid concentration in postmenopausal facial skin after topical estradiol and genistein treatment: a double-blind, randomized clinical trial of efficacy. Menopause 2013;20: 336–41
   PubMed Web of Science ®Google Scholar
• Condi FL, Soares JM Jr, Teodoro WR, et al. The effects of conjugated estrogen, raloxifene and soy extract on collagen in rat bones. Climacteric 2012;15:441–8
   PubMed Web of Science ®Google Scholar
• Florencio-Silva R, Santos MA, Medeiros VP, et al. Effecdts of soy isoflavones and mechanical vibration on rat bone tissue. Climacteric 2013;16:709–17
   PubMed Web of Science ®Google Scholar
• Santos MA, Florencio-Silva R, Simões MJ, et al. Efeitos das isoflavonas da soja sobre o tecido ósseo de ratas. Reprod Clim 2010;26:19–25
   Google Scholar
• Nozaka K, Miyakoshi N, Kasukawa Y, et al. Intermittent administration of human parathyroid hormone enhances bone formation and union at the site of cancellous bone osteotomy in normal and ovariectomized rats. Bone 2008;42:90–7
   PubMed Web of Science ®Google Scholar
• Parfitt AM, Drezner MK, Glorieux FH, et al. Bone histomorphometry: standardization of nomenclature, symbols, and units. J Bone Miner Res 1987;2:595–610
   PubMed Web of Science ®Google Scholar
• Aquiar JA, Lima CR, Berto AG, et al. An improved methodology to produce Flavobacterium heparinum chondroitinases, important instruments for diagnosis of diseases. Biotechnol Appl Biochem 2003;37:115–27
   PubMed Web of Science ®Google Scholar
• Keenam JM, Hegsted M, Jones LK, et al. Comparison of bone density measurement technique: DXA and Archimedes’ principle. J Bone Miner Res 1997;12:1903–7
   PubMed Web of Science ®Google Scholar
• Hughes SW. Archimedes revisited: a faster, better, cheaper method of accurately measuring the volume of small objects. Phys Educ 2005;40:468–74
   Google Scholar
• Kalu DN. The ovariectomized rat model of postmenopausal bone loss. Bone Min 1991;15:175–92
   PubMedGoogle Scholar
• Tempfer CB, Bentz EK, Leodolter S, et al. Phytoestrogens in clinical practice: a review of the literature. Fertil Steril 2007;87:1243–9
   PubMed Web of Science ®Google Scholar
• Arjmandi BH, Getlinger MJ, Goyal NV, et al. Role of soy protein with normal or reduced isoflavone content in reversing bone loss induced by ovarian hormone deficiency in rats. Am J Clin Nutr 1998;68:1358–63
   PubMed Web of Science ®Google Scholar
• Hertrampf T, Schleipen C, Offermanns M, et al. Comparison of the bone protective effects of an isoflavone-rich diet with dietary and subcutaneous administrations of genistein in ovariectomized rats. Toxicol Lett 2009;184:198–203
   PubMed Web of Science ®Google Scholar
• Kawakita S, Marota F, Naito Y, et al. Effect of an isoflavones-containing red clover preparation and alkaline supplementation on bone metabolism in ovariectomized rats. Clin Interv Agin 2009;4:91–100
   PubMed Web of Science ®Google Scholar
• Arjmandi BH, Alekel L, Hollis BW, et al. Dietary soybean protein prevents bone loss in an ovariectomized rat model of osteoporosis. J Nutr 1996;126:161–7
   PubMed Web of Science ®Google Scholar
• Ishida H, Uesugi T, Hirai K, et al. Preventive effects of the plant isoflavones, daidzin and genistin, on bone loss in ovariectomized rats fed a calcium deficient diet. Biol Pharm Bull 1998; 21:62–6
   PubMed Web of Science ®Google Scholar
• Picherit C, Chanteranne B, Bennetau-Pelissero C, et al. Dose-dependent bone sparing effects of dietary isoflavones in the ovariectomised rat. Br J Nutr 2001;85:307–16
   PubMed Web of Science ®Google Scholar
• Chang KL, Hu YC, Hsieh BS, et al. Combined effect of soy isoflavones and vitamin D3 on bone loss in ovariectomized rats. Nutrition 2013;29:250–7
   PubMed Web of Science ®Google Scholar
• Greendale GA, FitzGerald G, Huang M-H, et al. Dietary soy isoflavones and bone mineral density: results from the Study of Women's Health Across the Nation. Am J Epidemiol 2002; 155:746–54
   PubMed Web of Science ®Google Scholar
• Ho SC, Woo J, Lam S, et al. Soy protein consumption and bone mass in early postmenopausal Chinese women. Osteoporosis Int 2003;14:835–42
   PubMed Web of Science ®Google Scholar
• Sebastian A. Isoflavones, protein, and bone. Am J Clin Nutr 2005;81:733–5
   PubMed Web of Science ®Google Scholar
• Anderson JJ, Chen X, Boass A, et al. Soy isoflavones: no effects on bone mineral content and bone mineral density in healthy, menstruating young adult women after one year. J Am Coll Nutr 2002;21:388–93
   PubMed Web of Science ®Google Scholar
• Gallagher JC, Satpathy R, Rafferty K, et al. The effect of soy protein isolate on bone metabolism. Menopause 2004; 11:290–8
   PubMed Web of Science ®Google Scholar
• Cassidy A. Potential risks and benefits of phytoestrogen-rich diets. Int J Vitam Nutr Res 2003;73:120–6
   PubMed Web of Science ®Google Scholar
• Dang ZC, Lowik C. Dose-dependent effects of phytoestrogens on bone. Trends Endocrinol Metab 2005;16:207–13
   PubMed Web of Science ®Google Scholar
• Frost HM. Bone mass and the mechanostat: a proposal. Anat Rec 1987;219:1–9
   PubMedGoogle Scholar
• Bord S, Horner A, Beavan S, et al. Estrogen receptors alpha and beta are differentially expressed in developing human bone. J Clin Endocrinol Metab 2001;86:2309–14
   PubMed Web of Science ®Google Scholar
• Caverzasio J, Higgins L, Ammann P. Prevention of trabecular bone loss induced by estrogen deficiency by a selective p38alpha inhibitor. J Bone Miner Res 2008;23:1389–97
   PubMed Web of Science ®Google Scholar
• Breitman PL, Fonseca D, Cheung AM, et al. Isoflavones with supplemental calcium provide greater protection against the loss of bone mass and strength after ovariectomy compared to isoflavones alone. Bone 2003;33:597–605
   PubMed Web of Science ®Google Scholar
• Soung DY, Devareddy L, Khalil DA, et al. Soy affects trabecular microarchitecture and favorably alters select bone-specific gene expressions in a male rat model of osteoporosis. Calcif Tissue Int 2006;78:385–91
   PubMed Web of Science ®Google Scholar
• Conrad HE. Structure of heparan sulfate and dermatan sulfate. Ann NY Acad Sci 1989;556:18–28
   PubMed Web of Science ®Google Scholar
• Kjellén L, Lindahl U. Proteoglycans: structures and interactions. Ann Rev Biochem 1991;60:443–75
   PubMed Web of Science ®Google Scholar
• Dutt S, Matasci M, Sommer L, et al. Guidance of neural crest cell migration: the inhibitory function of the chondroitin sulfate proteoglycan, versican. Sci World J 2006;6:1114–17
   Web of Science ®Google Scholar
• Lopes CC, Dietrich CP, Nader HB. Specific structural features of syndecans and heparan sulfate chains are needed for cell signaling. Braz J Med Biol Res 2006;39:157–67
   PubMed Web of Science ®Google Scholar
• Prince CW, Rahemtulla F, Buttler WT. Metabolism of rat bone proteoglycans in vivo. Biochem J 1983;216:589–96
   PubMed Web of Science ®Google Scholar
• Hoshi K, Kemmotsu S, Takeuchi Y, et al. The primary calcification in bones follows removal of decorin and fusion of collagen fibrils. J Bone Miner Res 1999;14:273–80
   PubMed Web of Science ®Google Scholar
• Xu T, Bianco P, Fisher LW, et al. Targeted disruption of the biglycan gene leads to an osteoporosis-like phenotype in mice. Nat Genet 1998;20:78–82
   PubMed Web of Science ®Google Scholar
• Parry DAD, Flint MH, Gillard GC, et al. A role for glycosaminoglycans in the development of collagen fibrils. FEBS Letters 1982;149:1–7
   PubMed Web of Science ®Google Scholar
• Corsi A, Xu T, Chen XD, et al. Phenotypic effects of biglycan deficiency are linked to collagen fibril abnormalities, are synergized by decorin deficiency, and mimic Ehlers-Danlos-like changes in bone and other connective tissue. J Bone Miner Res 2002; 17:1180–9
   PubMed Web of Science ®Google Scholar