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Research Article

Soybean concentrated extract counteracts oxidative stress in the uterus of rats

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Pages 402-409 | Received 19 Sep 2013, Accepted 14 Oct 2013, Published online: 21 Nov 2013

References

  • Semchyshyn HM, Lushchak VI. Interplay between oxidative and carbonyl stresses: molecular mechanisms, biological effects and therapeutic strategies of protection. Int J Bioautomation 2012;16:15–46
  • Ascensão AA, Magalhães JF, Soares JM, et al. Cardiac mitochondrial respiratory function and oxidative stress: the role of exercise. Int J Sports Med 2005;26:258–67
  • Dröge W. Free radicals in the physiological control of cell function. Physiol Rev 2002;82:47–95
  • Shaw CA, Taylor E, Rossi AG, et al. Differential susceptibility to nitric oxide-evoked apoptosis in human inflammatory cells. Free Radic Biol Med 2011;50:93–101
  • Bertoncini CR, Meneghini R. DNA strand breaks produced by oxidative stress in mammalian cells exhibit 3’-phosphoglycolate termini. Nucleic Acids Res 1995;23:2995–3002
  • Kregel KC, Zhang HJ. An integrated view of oxidative stress in aging: basic mechanisms, functional effects, and pathological considerations. Am J Physiol Regul Integr Comp Physiol 2007; 292:18–36
  • Prokai L, Prokai-Tatrai K, Perjési P, et al. Mechanistic insights into the direct antioxidant effects of estrogens. DDR 2006;66: 118–25
  • Ruiz-Larrea B, Leal A, Martin C, et al. Effects of estrogens on the redox chemistry of iron: a possible mechanism of the antioxidant action of estrogens. Steroids 1995;60:780–3
  • Finkel T. Oxidant signals and oxidative stress. Curr Opin Cell Biol 2003;15:247–54
  • Uttara B, Singh AV, Zamboni P, et al. Oxidative stress and neurodegenerative diseases: a review of upstream and downstream antioxidant therapeutic options. Curr Neuropharmacol 2009; 7:65–74
  • Valko M, Leibfritz D, Moncol J, et al. Free radicals and antioxidants in normal physiological functions and human disease. Int J Biochem Cell Biol 2007;39:44–84
  • Corrao G, Zambon A, Conti V, et al. Menopause hormone replacement therapy and cancer risk: an Italian record linkage investigation. Ann Oncol 2008;19:150–5
  • Gaete L, Tchernitchin AN, Bustamante R, et al. Daidzein-estrogen interaction in the rat uterus and its effect on human breast cancer cell growth. J Med Food 2012;15:1081–90
  • Canonico M, Plu-Bureau G, Lowe GDO, et al. Hormone replacement therapy and risk of venous thromboembolism in postmenopausal women: systematic review and meta-analysis. BMJ 2008;336:1227–31
  • Magliano DJ, Rogers SL, Abramson MJ, et al. Hormone therapy and cardiovascular disease: a systematic review and meta-analysis. BJOG 2006;113:5–14
  • North American Menopause Society. The role of soy isoflavones in menopausal health: report of The North American Menopause Society/Wulf H. Utian Translational Science Symposium in Chicago, IL (October 2010). Menopause 2011; 18:732–53
  • Erba D, Casiraghi MC, Martinez-Conesa C, et al. Isoflavone supplementation reduces DNA oxidative damage and increases O-β-N-acetyl-D-glucosaminidase activity in healthy women. Nutr Res 2012;32:233–40
  • Bahr JM, Nakai M, Rivera A, et al. Dietary soy protein and isoflavones: minimal beneficial effects on bone and no effect on the reproductive tract of sexually mature ovariectomized Sprague-Dawley rats. Menopause 2005;12:165–73
  • Carbonel AA, Baracat MC, Simões RS, et al. The soybean concentrated extract proliferates the vagina of adult rats. Menopause 2011;18:93–101
  • Carbonel AA, Simões RS, Santos RH, et al. Effects of high-dose isoflavones on rat uterus. Rev Assoc Med Bras 2011; 57:534–9
  • Rufer CE, Kulling SE. Antioxidant activity of isoflavones and their major metabolites using different in vitro assays. J Agric Food Chem 2006;54:2926–31
  • Setchell KD, Cassidy A. Dietary isoflavones: biological effects and relevance to human health. J Nutr 1999;129:758–67
  • Unfer V, Casini ML, Costabile L, et al. Endometrial effects of long-term treatment with phytoestrogens: a randomized, double-blind, placebo-controlled study. Fertil Steril 2004; 82:145–8
  • Oseni T, Patel R, Pyle J, et al. Selective estrogen receptor modulators and phytoestrogens. Planta Med 2008; 74:1656–65
  • Rossouw JE, Andersos GL, Prentice RL, et al. Risks and benefits of estrogen plus progestin in health postmenopausal women: principal results from the Women's Health Initiative randomized controlled trial. JAMA 2002;288:321–33
  • Salleh N, Helmy MM, Fadila KN, et al. Isoflavone genistein induces fluid secretion and morphological changes in the uteri of post-pubertal rats. Int J Med Sci 2013;10:665–75
  • Balk JL, Whiteside DA, Naus G, et al. A pilot study of the effects of phytoestrogen supplementation on postmenopausal endometrium. J Soc Gynecol Investig 2002;9:238–42
  • Quaas AM, Kono N, Mack WJ, et al. Effect of isoflavone soy protein supplementation on endometrial thickness, hyperplasia, and endometrial cancer risk in postmenopausal women: a randomized controlled trial. Menopause 2013;20:1–5
  • Santos ET, Sampaio MD, Cecon PR, et al. Effects of soy isoflavones on the uterus and urethra of ovariectomized rats. Int Urogynecol J 2010;21:111–16
  • Unfer V, Casini ML, Costabile L, et al. Endometrial effects of long-term treatment with phytoestrogens: a randomized, double-blind, placebo-controlled study. Fertil Steril 2004;82: 145–8
  • Carthew P, Edwards RE, Nolan BM, et al. Compartmentalized uterotrophic effects of tamoxifen, toremifene, and estradiol in the ovariectomized Wistar (Han) rat. Toxicol Sci 1999;48: 197–205
  • Judd HL, Mebane-Sims I, Legault C, et al. Effects of hormone replacement therapy on endometrial histology in postmenopausal women. The Postmenopausal Estrogen/Progestin Interventions (PEPI) Trial. JAMA 1996;275:370–5
  • Selman C, Blount JD, Nussey DH, et al. Oxidative damage, ageing, and life-history evolution: where now?. Trends Ecol Evol 2012;27:570–7
  • Kregel KC, Zhang HJ. An integrated view of oxidative stress in aging: basic mechanisms, functional effects, and pathological considerations. Am J Physiol Regul Integr Comp Physiol 2007;292:18–36
  • Evsen MS, Ozler A, Gocmez C, et al. Effects of estrogen, estrogen/progesterone combination and genistein treatments on oxidant/antioxidant status in the brain of ovariectomized rats. Eur Rev Med Pharmacol Sci 2013;17:1869–73
  • Chen JT, Kotani K. An inverse relation between the Simplified Menopausal Index and biological antioxidant potential. Climacteric 2013;16:288–91
  • Nathan L, Chaudhuri G. Antioxidant and prooxidant actions of estrogens: potential physiological and clinical implications. Semin Reprod Endocrinol 1998;16:309–14
  • Sánchez Rodríguez MA, Zacarías Flores M, Arronte Rosales A. Effect of hormone therapy with estrogens on oxidative stress and quality of life in postmenopausal women. Ginecol Obstet Mex 2013;81:11–22
  • Castanho VS, Nakamura RT, Pinto-Neto AM, et al. Postmenopausal therapy reduces catalase activity and attenuates cardiovascular risk. Arq Bras Cardiol 2012;99:1008–14
  • Zhu X, Tang Z, Cong B, et al. Estrogens increase cystathionine-γ-lyase expression and decrease inflammation and oxidative stress in the myocardium of ovariectomized rats. Menopause 2013;20:1084–91
  • Green K, Brand MD, Murphy MP. Prevention of mitochondrial oxidative damage as a therapeutic strategy in diabetes. Diabetes 2004;53:110–18
  • Escalante-Gómez C, Quesada MS. HRT decreases DNA and lipid oxidation in postmenopausal women. Climacteric 2013;16: 104–10
  • Mobley JA, Bruegggemeler RW. Estrogen receptor-mediated regulation of oxidative stress and damage in breast cancer. Carcinogenisis 2004;25:3–9
  • Pajovic SB, Saicic ZS. Modulation of antioxidant enzyme activities by sexual steroid hormones. Physiol Res 2008;57: 801–11
  • Hekimoglu A, Bilgin HM, Kurcer Z, et al. Effects of increasing ratio of progesterone in estrogen/progesterone combination on total oxidant/antioxidant status in rat uterus and plasma. Arch Gynecol Obstet 2010;281:23–8
  • Azadbakht L, Kimiagar M, Mehrabi Y, et al. Dietary soya intake alters plasma antioxidant status and lipid peroxidation in postmenopausal women with the metabolic syndrome. Br J Nutr 2007;98:807–13
  • Möller FJ, Ledwig C, Zierau O, et al. The rat prepubertal uterine myometrium and not the luminal epithelium is predominantly affected by a chronic dietary genistein exposure. Arch Toxicol 2012;86:1899–910
  • Lephart ED, Setchell KD, Handa RJ, et al. Behavioral effects of endocrine-disrupting substances: phytoestrogens. ILAR J 2004; 45:443–54
  • Qian Y, Guan T, Huang M, et al. Neuroprotection by the soy isoflavone, genistein, via inhibition of mitochondria-dependent apoptosis pathways and reactive oxygen induced-NF-κB activation in a cerebral ischemia mouse model. Neurochem Int 2012;60:759–67

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