Linoleic and alpha linolenic acids ameliorate streptozotocin-induced diabetes in mice

References

• Audi N, Mesa MD, Martínez MA, et al. (2007). Membrane lipid composition of pancreatic AR42J cells: modification by exposure to different fatty acids. Exp Biol Med, 232:532–41
   Web of Science ®Google Scholar
• Bellenger J, Bellenger S, Bataille A, et al. (2011). High pancreatic n-3 fatty acids prevent STZ-induced diabetes in Fat-1 mice: inflammatory pathway inhibition. Diabetes, 60:1090–9
   PubMed Web of Science ®Google Scholar
• Brenner RR. (2003). Hormonal modulation of Δ6 and Δ5 desaturases: case of diabetes. Prostaglandins Leukot Essent Fatty Acids, 68:151–62
   PubMed Web of Science ®Google Scholar
• Brown JE. (2005). A critical review of methods used to estimate linoleic acid Δ6-desaturation ex vivo and in vivo. Eur J Lipid Sci Technol, 107:119–34
   Web of Science ®Google Scholar
• Dokko RC, Cho BH, Chung BH. (1998). Cellular uptake of stearic, oleic, linoleic, and linolenic acid and their effects on synthesis and secretion of lipids in Hep-G2 cells. Int J Biochem Cell Biol, 30:65–76
   PubMed Web of Science ®Google Scholar
• Howell RW, Collins FI. (1957). Factors affecting linolenic and linoleic acid content of soybean oil. Agronomy J, 49:593–7
   Google Scholar
• Itoh Y, Hinuma S. (2005). GPR40, a free fatty acid receptor on pancreatic beta cells, regulates insulin secretion. Hepatol Res, 33:171–3
   PubMed Web of Science ®Google Scholar
• Itoh Y, Kawamata Y, Harada M, et al. (2003). Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40. Nature, 422:173–6
   PubMed Web of Science ®Google Scholar
• Jeng JY, Chiu YH, Lee YC, Hsieh RH. (2009). Linoleic acid promotes mitochondrial biogenesis and maintains mitochondrial structure for prevention of streptozotocin damage in RIN-m5F cells. Biosci Biotechnol Biochem, 73:1262–7
   PubMed Web of Science ®Google Scholar
• Kagohashi Y, Abiru N, Kobayashi M, et al. (2010). Maternal dietary n-6/n-3 fatty acid ratio affects type 1 diabetes development in the offspring of non-obese diabetic mice. Congen Anom, 50:212–20
   PubMedGoogle Scholar
• Kliewer SA, Sundseth SS, Jones SA, et al. (1997). Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors alpha and gamma. Proc Natl Acad Sci USA, 9:4318–23
   Google Scholar
• Krishna MI, Das UN. (2001). Prevention of chemically induced diabetes mellitus in experimental animals by polyunsaturated fatty acids. Nutrition, 17:126–51
   PubMed Web of Science ®Google Scholar
• Leikin Frenkel A, Canetti L, Halpern Z. (2004). Effects of nutritional lipids on diabetic manifestations and Δ6 desaturase mRNA level in streptozotocin treated mice. Nutrition Research, 24:303–12
   Web of Science ®Google Scholar
• Nolan CJ, Murthy SR, Madijaru V, Peyot ML. (2006). Fatty acid signaling in the β-cell and insulin secretion. Diabetes, 55:S16–23
   PubMed Web of Science ®Google Scholar
• Poitout V. (2003). The ins and outs of fatty acids on the pancreatic beta cell. Trends Endocrinol Metab, 14:201–3
   PubMed Web of Science ®Google Scholar
• Rimoldi OJ, Finarelli GS, Brenner RR. (2001). Effects of diabetes and insulin on hepatic delta 6 desaturase gene expression. Biochem Biophys Res Commun, 283:323–6
   PubMed Web of Science ®Google Scholar
• Rojo-Martínez G, Esteva I, Ruiz de Adana MS, et al. (2006). Dietary fatty acids and insulin secretion: a population-based study. Euro J Clin Nutrition, 60:1195–200
   PubMed Web of Science ®Google Scholar
• Seti H, Leikin-Frenkel A, Werner H. (2009). Effects of omega-3 and omega-6 fatty acids on IGF-I receptor signaling in colorectal cancer cells. Arch Physiol Biochem, 115:127–36
   PubMedGoogle Scholar
• Suresh Y, Das UN. (2001). Protective action of arachidonic acid against alloxan-induced cytotoxicity and diabetes mellitus. Prostaglandins Leukot Essent Fatty Acids, 64:37–52
   PubMed Web of Science ®Google Scholar
• Suresh Y, Das UN. (2003). Long-chain polyunsaturated fatty acids and chemically induced diabetes mellitus: Effect of ω-6 fatty acids. Nutrition, 19:93–114
   PubMed Web of Science ®Google Scholar
• Suresh Y, Das UN. (2006). Differential effect of saturated, monounsaturated, and polyunsaturated fatty acids on alloxan-induced diabetes mellitus. Prostaglandins Leukot Essent Fatty Acids, 74:199–213
   PubMed Web of Science ®Google Scholar
• Szkudelski T. (2001). The mechanism of alloxan and streptozotocin action in β cells of the rat pancreas. Physiol Res, 50:536–46
   Web of Science ®Google Scholar
• Szkudelsky T. (2012). Streptozotocin-nicotinamide-induced diabetes in the rat. Characteristics of the experimental model. Exp Biology Med, 237:481–90
   Web of Science ®Google Scholar
• Tang C, Cho HP, Nakamura MT, Clarke SD. (2003). Regulation of human delta-6 desaturase gene transcription: identification of a functional direct repeat-1 element. J Lipid Res, 44:686–95
   PubMed Web of Science ®Google Scholar
• Ventura-Sobrevilla J, Boone-Villa VD, Aguilar CN, et al. (2011). Effect of varying dose and administration of streptozotocin on blood sugar in male CD1 mice. Proc West Pharmacol Soc, 54:5–9
   PubMedGoogle Scholar