Advanced search
Publication Cover
Ophthalmic Genetics Volume 36, 2015 - Issue 1
Submit an article Journal homepage
336
Views
9
CrossRef citations to date
0
Altmetric
Research Report

Evaluating the Association between Pathological Myopia and SNPs in RASGRF1. ACTC1 and GJD2 Genes at Chromosome 15q14 and 15q25 in a Chinese Population

Chong-da ChenKey Laboratory of Myopia, Ministry of Health, Shanghai, China, ;The Affiliated Cixi Hospital of Wenzhou Medical College, Cixi, China, and
,
Zhi-qiang YuKey Laboratory of Myopia, Ministry of Health, Shanghai, China, ;Eye Department, Eye&ENT Hospital, Fudan University, Shanghai, ChinaCorrespondence[email protected]
,
Xue-li ChenEye Department, Eye&ENT Hospital, Fudan University, Shanghai, China
,
Jia-qi ZhouEye Department, Eye&ENT Hospital, Fudan University, Shanghai, China
,
Xing-tao ZhouKey Laboratory of Myopia, Ministry of Health, Shanghai, China, ;Eye Department, Eye&ENT Hospital, Fudan University, Shanghai, China
,
Xing-huai SunKey Laboratory of Myopia, Ministry of Health, Shanghai, China, ;Eye Department, Eye&ENT Hospital, Fudan University, Shanghai, China
&
Ren-yuan ChuKey Laboratory of Myopia, Ministry of Health, Shanghai, China, ;Eye Department, Eye&ENT Hospital, Fudan University, Shanghai, China
 show all
Pages 1-7 | Received 21 Feb 2013, Accepted 02 Jun 2013, Published online: 08 Jul 2013

References

  • Yu L, Li ZK, Gao JR, et al. Epidemiology, genetics and treatments for myopia. Int J Ophthalmol 2011;4:658–669
  • Zejmo M, Formińska-Kapuścik M, Pieczara E, et al. Etiopathogenesis and management of high-degree myopia. Part I. Med Sci Monit 2009;15:RA199–202
  • Wong TY, Foster PJ, Hee J, et al. Prevalence and risk factors for refractive errors in adult Chinese in Singapore. Invest Ophthalmol Vis Sci 2000;41:2486–2494
  • Lin LL, Shih YF, Hsiao CK, et al. Epidemiologic study of the prevalence and severity of myopia among schoolchildren in Taiwan in 2000. J Formos Med Assoc 2001;100:684–691
  • Lin LL, Shih YF, Tsai CB, et al. Epidemiologic study of ocular refraction among schoolchildren in Taiwan in 1995. Optom Vis Sci 1999;76:275–281
  • Lin LL, Shih YF, Hsiao CK, Chen CJ. Prevalence of myopia in Taiwanese schoolchildren: 1983 to 2000. Ann Acad Med Singapore 2004;33:27–33
  • Cordain L, Eaton SB, Brand Miller J, et al. An evolutionary analysis of the aetiology and pathogenesis of juvenile-onset myopia. Acta Ophthalmol Scand 2002;80:125–135
  • Baird PN, Schäche M, Dirani M. The GEnes in Myopia (GEM) study in understanding the aetiology of refractive errors. Prog Retin Eye Res 2010;29:520–542
  • Dirani M, Chamberlain M, Shekar SN, et al. Heritability of refractive error and ocular biometrics: the Genes in Myopia (GEM) twin study. Invest Ophthalmol Vis Sci 2006;47:4756–4761
  • Morgan IG, Ohno-Matsui K, Saw SM. Myopia. Lancet 2012;379:1739–1748
  • Hammond CJ, Snieder H, Gilbert CE, Spector TD. Genes and environment in refractive error: the twin eye study. Invest Ophthalmol Vis Sci 2001;42:1232–1236
  • Liang CL, Yen E, Su JY, et al. Impact of family history of high myopia on level and onset of myopia. Invest Ophthalmol Vis Sci 2004;45:3446–3452
  • Zhang Q, Guo X, Xiao X, et al. A new locus for autosomal dominant high myopia maps to 4q22-q27 between D4S1578 and D4S1612. Mol Vis 2005;11:554–560
  • Jacobi FK, Pusch CM. A decade in search of myopia genes. Front Biosci 2010;15:359–372
  • Wojciechowski R. Nature and nurture: the complex genetics of myopia and refractive error. Clin Genet 2011;79:301–320
  • Hysi PG, Young TL, Mackey DA, et al. A genome-wide association study for myopia and refractive error identifies a susceptibility locus at 15q25. Nat Genet 2010;42:902–905
  • Solouki AM, Verhoeven VJ, van Duijn CM, et al. A genome-wide association study identifies a susceptibility locus for refractive errors and myopia at 15q14. Nat Genet 2010;42:897–901
  • Verhoeven VJ, Hysi PG, Wojciechowski R, et al.; Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Research Group, Evans DM, Timpson NJ, Verkerk AJ, et al.; Fuchs’ Genetics Multi-Center Study Group, Gorgels TG, Rudan I, Hayward C, et al. Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia. Nat Genet 2013;45:314–318
  • Verhoeven VJ, Hysi PG, Saw SM, et al. Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium. Hum Genet 2012;131:1467--80
  • Jiao X, Wang P, Li S, et al. Association of markers at chromosome 15q14 in Chinese patients with moderate to high myopia. Mol Vis 2012;18:2633–2646
  • Kiefer AK, Tung JY, Do CB, et al. Genome-wide analysis points to roles for extracellular matrix remodeling, the visual cycle, and neuronal development in myopia. PLoS Genet 2013;9:e1003299. doi: 10.1371/journal.pgen.1003299. Epub 2013 Feb 28
  • Fernández-Medarde A, Barhoum R, Riquelme R, et al. RasGRF1 disruption causes retinal photoreception defects and associated transcriptomic alterations. J Neurochem 2009;110:641–652
  • Hayashi H, Yamashiro K, Nakanishi H, et al. Association of 15q14 and 15q25 with high myopia in Japanese. Invest Ophthalmol Vis Sci 2011;52:4853–4858
  • van der Schaft TL, Mooy CM, de Bruijn WC, et al. Histologic features of the early stages of age-related macular degeneration. A statistical analysis. Ophthalmology 1992;99:278–286

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.