Association of polymorphisms in complement component 3 with age-related macular degeneration in an Iranian population

References

• Haddad S, Chen CA, Santangelo SL. The genetics of age-related macular degeneration: a review of progress to date. Surv Ophthalmol 2006;51:316–363.
   PubMed Web of Science ®Google Scholar
• Klein R, Peto T, Bird A, et al. The epidemiology of age-related macular degeneration. Am J Ophthalmol 2004;137:486–495.
   PubMed Web of Science ®Google Scholar
• Chakravarthy U, Augood C, Bentham GC, et al. Cigarette smoking and age-related macular degeneration in the EUREYE Study. Ophthalmology 2007;114:1157–1163.
   PubMed Web of Science ®Google Scholar
• Mullins RF. Genetic insights into the pathobiology of age-related macular degeneration. Int Ophthalmol Clin 2007;47:1–14.
   PubMedGoogle Scholar
• Friedman DS, O’Colmain BJ, Muñoz B, et al; Eye Diseases Prevalence Research Group. Prevalence of age-related macular degeneration in the United States. Arch Ophthalmol 2004;122:564–572.
   Google Scholar
• Zarbin MA. Current concepts in the pathogenesis of age-related macular degeneration. Arch Ophthalmol 2004;122:598–614.
   PubMed Web of Science ®Google Scholar
• Johnson LV, Leitner WP, Staples MK, et al. Complement activation and inflammatory processes in drusen formation and age-related macular degeneration. Exp Eye Res 2001;73:887–896.
   PubMed Web of Science ®Google Scholar
• Anderson DH, Mullins RF, Hageman GS, et al. A role for local inflammation in the formation of drusen in the aging eye. Am J Ophthalmol 2002;134:411–431.
   PubMed Web of Science ®Google Scholar
• Johnson L, Ozaki S, Staples M, et al. A potential role for immune complex pathogenesis in drusen formation. Exp Eye Res 2000;70:441–449.
   PubMed Web of Science ®Google Scholar
• Klein RJ, Zeiss C, Chew EY, et al. Complement factor H polymorphism in age-related macular degeneration. Science 2005;308(572):385–389.
   PubMed Web of Science ®Google Scholar
• Spencer KL, Hauser MA, Olson LM, et al. Protective effect of complement factor B and complement component 2 variants in age-related macular degeneration. Hum Mol Genet 2007;16:1986–1992.
   PubMed Web of Science ®Google Scholar
• Hageman GS, Anderson DH, Johnson LV, et al. A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration. PNAS 2005;102:7227–7232.
   PubMed Web of Science ®Google Scholar
• Ormsby RJ, Ranganathan S, Tong JC, et al. Functional and structural implications of the complement factor H Y402H polymorphism associated with age-related macular degeneration. Invest Ophthalmol Vis Sci 2008;49:1763–1770.
   PubMed Web of Science ®Google Scholar
• Yates JR, Sepp T, Matharu BK, et al; Genetic Factors in AMD Study Group. Complement C3 variant and the risk of age-related macular degeneration. N Engl J Med 2007;357:553–561.
   Google Scholar
• Despriet DD, van Duijn CM, Oostra BA, et al. Complement component C3 and risk of age-related macular degeneration. Ophthalmology 2009;116:474–480.
   PubMed Web of Science ®Google Scholar
• Maller JB, Fagerness JA, Reynolds RC, et al. Variation in complement factor 3 is associated with risk of age-related macular degeneration. Nat Genet 2007;39:1200–1201.
   PubMed Web of Science ®Google Scholar
• Spencer KL, Olson LM, Anderson BM, et al. C3 R102G polymorphism increases risk of age-related macular degeneration. Hum Mol Genet 2008;14:1821–1824.
   Web of Science ®Google Scholar
• Nozaki M, Raisler BJ, Sakurai E, et al. Drusen complement components C3a and C5a promote choroidal neovascularization. Proc Natl Acad Sci USA 2006;103:2328–2333.
   PubMed Web of Science ®Google Scholar
• Bird AC, Bressler NM, Bressler SB, et al. An international classification and grading system for age-related maculopathy and age-related macular degeneration. The International ARM Epidemiological Study Group. Surv Ophthalmol 1995;39:367–374.
   PubMed Web of Science ®Google Scholar
• Cui L, Zhou H, Yu J, et al. Noncoding variant in the complement factor H gene and risk of exudative age-related macular degeneration in a Chinese population. Invest Ophthalmol Vis Sci 2010;51:1116–1120.
   PubMed Web of Science ®Google Scholar
• Walport MJ. Complement. First of two parts. N Engl J Med 2001;344:1058–1066.
   PubMed Web of Science ®Google Scholar
• Janssen BJ, Christodoulidou A, McCarthy A, et al. Structure of C3b reveals conformational changes that underlie complement activity. Nature 2006;444:213–216.
   PubMed Web of Science ®Google Scholar
• Bora PS, Hu Z, Tezel TH, et al. Immunotherapy for choroidal neovascularization in a laser-induced mouse model simulating exudative (wet) macular degeneration. Proc Natl Acad Sci USA 2003;100:2679–2684.
   PubMed Web of Science ®Google Scholar
• Heurich M, Martínez-Barricarte R, Francis NJ, et al. Common polymorphisms in C3, factor B, and factor H collaborate to determine systemic complement activity and disease risk. Proc Natl Acad Sci USA 2011;108:8761–8766.
   PubMed Web of Science ®Google Scholar
• Francis PJ, Hamon SC, Ott J, et al. Polymorphisms in C2, CFB and C3 are associated with progression to advanced age related macular degeneration associated with visual loss. J Med Genet 2009;46:300–307.
   PubMed Web of Science ®Google Scholar
• Zerbib J, Richard F, Puche N, et al. R102G polymorphism of the C3 gene associated with exudative age-related macular degeneration in a French population. Mol Vis 2010;16:1324–1330.
   PubMed Web of Science ®Google Scholar
• Thakkinstian A, McKay GJ, McEvoy M, et al. Systematic review and meta-analysis of the association between complement component 3 and age-related macular degeneration: a HuGE review and meta-analysis. Am J Epidemiol 2011;173:1365–1379.
   PubMed Web of Science ®Google Scholar
• Pei XT, Li XX, Bao YZ, et al. Association of C3 gene polymorphisms with neovascular age-related macular degeneration in a Chinese population. Curr Eye Res 2009;34:615–622.
   PubMed Web of Science ®Google Scholar
• Liu X, Zhao P, Tang S, et al. Association study of complement factor H, C2, CFB, and C3 and age-related macular degeneration in a Han Chinese population. Retina 2010;30:1177–1184.
   PubMed Web of Science ®Google Scholar
• Botto M, Fong KY, So AK, et al. Molecular basis of polymorphisms of human complement component C3. J Exp Med 1990;172:1011–1017.
   PubMed Web of Science ®Google Scholar
• Arvilommi H. Capacity of complement c3 phenotypes to bind on to mononuclear cells in man. Nature 1974;251:740–741.
   PubMed Web of Science ®Google Scholar
• Scholl HP, Fleckenstein M, Fritsche LG, et al. CFH, C3 and ARMS2 are significant risk loci for susceptibility but not for disease progression of geographic atrophy due to AMD. PLoS One 2009;4:e7418.
   PubMed Web of Science ®Google Scholar
• McKay GJ, Dasari S, Patterson CC, et al. Complement component 3: an assessment of association with AMD and analysis of gene-gene and gene-environment interactions in a Northern Irish cohort. Mol Vis 2010;16:194–199.
   PubMed Web of Science ®Google Scholar
• Seitsonen SP, Onkamo P, Peng G, et al. Multifactor effects and evidence of potential interaction between complement factor H Y402H and LOC387715 A69S in age-related macular degeneration [electronic article]. PLoS One 2008;3:e3833.
   PubMed Web of Science ®Google Scholar
• Park KH, Fridley BL, Ryu E, et al. Complement component 3 (C3) haplotypes and risk of advanced age-related macular degeneration. Invest Ophthalmol Vis Sci 2009; 50:3386–3393.
   PubMed Web of Science ®Google Scholar