1,621
Views
54
CrossRef citations to date
0
Altmetric
Research Article

Ligustrazine improves atherosclerosis in rat via attenuation of oxidative stress

, , , &
Pages 856-863 | Received 27 Jul 2010, Accepted 30 Dec 2010, Published online: 10 May 2011

References

  • Castelli WP, Garrison RJ, Wilson PW, Abbott RD, Kalousdian S, Kannel WB. (1986). Incidence of coronary heart disease and lipoprotein cholesterol levels. The Framingham Study. JAMA, 256, 2835–2838.
  • Chang Y, Hsiao G, Chen SH, Chen YC, Lin JH, Lin KH, Chou DS, Sheu JR. (2007). Tetramethylpyrazine suppresses HIF-1alpha, TNF-alpha, and activated caspase-3 expression in middle cerebral artery occlusion-induced brain ischemia in rats. Acta Pharmacol Sin, 28, 327–333.
  • Clarke LA, Shah V, Arrigoni F, Eleftheriou D, Hong Y, Halcox J, Klein N, Brogan PA. (2008). Quantitative detection of circulating endothelial cells in vasculitis: Comparison of flow cytometry and immunomagnetic bead extraction. J Thromb Haemost, 6, 1025–1032.
  • Duprez DA, Cohn JN. (2007). Arterial stiffness as a risk factor for coronary atherosclerosis. Curr Atheroscler Rep, 9, 139–144.
  • Goldstein JL, Hazzard WR, Schrott HG, Bierman EL, Motulsky AG. (1973). Hyperlipidemia in coronary heart disease. I. Lipid levels in 500 survivors of myocardial infarction. J Clin Invest, 52, 1533–1543.
  • Gordon DJ, Probstfield JL, Garrison RJ, Neaton JD, Castelli WP, Knoke JD, Jacobs DR Jr, Bangdiwala S, Tyroler HA. (1989). High-density lipoprotein cholesterol and cardiovascular disease. Four prospective American studies. Circulation, 79, 8–15.
  • Gordon T, Castelli WP, Hjortland MC, Kannel WB, Dawber TR. (1977). High density lipoprotein as a protective factor against coronary heart disease. The Framingham Study. Am J Med, 62, 707–714.
  • Hansson GK. (2009). Inflammatory mechanisms in atherosclerosis. J Thromb Haemost, 7 (Suppl 1), 328–331.
  • Hashimoto T, Cook WS, Qi C, Yeldandi AV, Reddy JK, Rao MS. (2000). Defect in peroxisome proliferator-activated receptor alpha-inducible fatty acid oxidation determines the severity of hepatic steatosis in response to fasting. J Biol Chem, 275, 28918–28928.
  • Holvoet P, Lee DH, Steffes M, Gross M, Jacobs DR Jr. (2008). Association between circulating oxidized low-density lipoprotein and incidence of the metabolic syndrome. JAMA, 299, 2287–2293.
  • Hsiai T, Berliner JA. (2007). Oxidative stress as a regulator of murine atherosclerosis. Curr Drug Targets, 8, 1222–1229.
  • Illingworth DR, Bacon S. (1987). Hypolipidemic effects of HMG-CoA reductase inhibitors in patients with hypercholesterolemia. Am J Cardiol, 60, 33G–42G.
  • Ishigaki Y, Oka Y, Katagiri H. (2009). Circulating oxidized LDL: A biomarker and a pathogenic factor. Curr Opin Lipidol, 20, 363–369.
  • Kim JW, Kang KW, Oh GT, Song J, Kim ND, Pak YK. (2002). Induction of hepatic inducible nitric oxide synthase by cholesterol in vivo and in vitro. Exp Mol Med, 34, 137–144.
  • Kitagawa S, Yamaguchi Y, Kunitomo M, Imaizumi N, Fujiwara M. (1993). Altered vasoconstrictor responsiveness in vitamin D-induced arteriosclerotic rat aortas. Jpn J Pharmacol, 61, 283–289.
  • Kobayashi S, Inoue N, Azumi H, Seno T, Hirata K, Kawashima S, Hayashi Y, Itoh H, Yokozaki H, Yokoyama M. (2002). Expressional changes of the vascular antioxidant system in atherosclerotic coronary arteries. J Atheroscler Thromb, 9, 184–190.
  • Li YJ, Li YJ, Wu JX, Yu XJ, Yan YF. (1994). Protective effect of tetramethylpyrazine against damages of aortic endothelial cells elicited by low-density lipoproteins. Zhongguo Yao Li Xue Bao, 15, 407–410.
  • Lizardi-Cervera J, Aguilar-Zapata D. (2009). Nonalcoholic fatty liver disease and its association with cardiovascular disease. Ann Hepatol, 8 (Suppl 1), S40–S43.
  • Makin AJ, Chung NA, Silverman SH, Lip GY. (2003). Thrombogenesis and endothelial damage/dysfunction in peripheral artery disease. Relationship to ethnicity and disease severity. Thromb Res, 111, 221–226.
  • Muniyappa R, Montagnani M, Koh KK, Quon MJ. (2007). Cardiovascular actions of insulin. Endocr Rev, 28, 463–491.
  • Peng W, Hucks D, Priest RM, Kan YM, Ward JP. (1996). Ligustrazine-induced endothelium-dependent relaxation in pulmonary arteries via an NO-mediated and exogenous l-arginine-dependent mechanism. Br J Pharmacol, 119, 1063–1071.
  • Puddu GM, Cravero E, Arnone G, Muscari A, Puddu P. (2005). Molecular aspects of atherogenesis: New insights and unsolved questions. J Biomed Sci, 12, 839–853.
  • Roberts CK, Barnard RJ, Sindhu RK, Jurczak M, Ehdaie A, Vaziri ND. (2006). Oxidative stress and dysregulation of NAD(P)H oxidase and antioxidant enzymes in diet-induced metabolic syndrome. Metab Clin Exp, 55, 928–934.
  • Seyama Y, Wachi H. (2004). Atherosclerosis and matrix dystrophy. J Atheroscler Thromb, 11, 236–245.
  • Singh U, Jialal I. (2006). Oxidative stress and atherosclerosis. Pathophysiology, 13, 129–142.
  • Soccio M, Toniato E, Evangelista V, Carluccio M, De Caterina R. (2005). Oxidative stress and cardiovascular risk: The role of vascular NAD(P)H oxidase and its genetic variants. Eur J Clin Invest, 35, 305–314.
  • Song S, Zhang Y, Ma K, Jackson-Hayes L, Lavrentyev EN, Cook GA, Elam MB, Park EA. (2004). Peroxisomal proliferator activated receptor gamma coactivator (PGC-1alpha) stimulates carnitine palmitoyltransferase I (CPT-Ialpha) through the first intron. Biochim Biophys Acta, 1679, 164–173.
  • St-Pierre J, Drori S, Uldry M, Silvaggi JM, Rhee J, Jäger S, Handschin C, Zheng K, Lin J, Yang W, Simon DK, Bachoo R, Spiegelman BM. (2006). Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators. Cell, 127, 397–408.
  • Sun Y, Jiang J, Zhang Z, Yu P, Wang L, Xu C, Liu W, Wang Y. (2008). Antioxidative and thrombolytic TMP nitrone for treatment of ischemic stroke. Bioorg Med Chem, 16, 8868–8874.
  • Sutter MC, Wang YX. (1993). Recent cardiovascular drugs from Chinese medicinal plants. Cardiovasc Res, 27, 1891–1901.
  • Victor VM, Rocha M, Solá E, Bañuls C, Garcia-Malpartida K, Hernández-Mijares A. (2009). Oxidative stress, endothelial dysfunction and atherosclerosis. Curr Pharm Des, 15, 2988–3002.
  • Wong KL, Chan P, Huang WC, Yang TL, Liu IM, Lai TY, Tsai CC, Cheng JT. (2003). Effect of tetramethylpyrazine on potassium channels to lower calcium concentration in cultured aortic smooth muscle cells. Clin Exp Pharmacol Physiol, 30, 793–798.
  • Woo KS, Chook P, Raitakari OT, McQuillan B, Feng JZ, Celermajer DS. (1999). Westernization of Chinese adults and increased subclinical atherosclerosis. Arterioscler Thromb Vasc Biol, 19, 2487–2493.
  • Wu GX, Wu JC, Ma HT, Ruan CG. (1992). Inhibitory effects of tetramethylpyrazine on platelets during cardiopulmonary bypass and arterial thrombus formation in dogs. Zhongguo Yao Li Xue Bao, 13, 330–333.
  • Zhang ZH, Yu SZ, Wang ZT, Zhao BL, Hou JW, Yang FJ, Xin WJ. (1994). Scavenging effects of tetramethylpyrazine on active oxygen free radicals. Zhongguo Yao Li Xue Bao, 15, 229–231.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.