Protective effect of saffron extract against doxorubicin cardiotoxicity in isolated rabbit heart

References

• Abd-Allah A, Al-Majed A, Mostafa A, et al. (2002). Protective effect of Arabic gum against cardiotoxicity induced by doxorubicin in mice: A possible mechanism of protection. J Biochem Mol Toxicol 16:254–9
   PubMed Web of Science ®Google Scholar
• Abdullaev FI. (2002). Cancer chemopreventive and tumoricidal properties of saffron (Crocus sativus). Exp Biol Med 227:20–5
   PubMed Web of Science ®Google Scholar
• Bagchi D, Sen CK, Ray SD, et al. (2003). Molecular mechanisms of cardioprotection by a novel grape seed proanthocyanidin extract. Mutat Res 523–524:87–97
   PubMed Web of Science ®Google Scholar
• Breitbart E, Lomnitski L, Nyska A, et al. (2001). Effects of water-soluble antioxidant from spinach, NAO, on doxorubicin-induced heart injury. Hum Exp Toxicol 20:337–45
   PubMedGoogle Scholar
• Chopra S, Pillai KK, Husain SZ, Giri DK. (1995). Propolis protects against doxorubicin-induced myocardiopathy in rats. Exp Mol Pathol 62:190–8
   PubMed Web of Science ®Google Scholar
• Dalloz F, Maingon P, Cottin Y, et al. (1999). Effects of combined irradiation and doxorubicin treatment on cardiac function and antioxidant defenses in the rat. Free Radic Biol Med 26:785–800
   PubMed Web of Science ®Google Scholar
• DeAtley SM, Aksenov MY, Aksenova MV, et al. (1999). Antioxidants protect against reactive oxygen species associated with adriamycin-treated cardiomyocytes. Cancer Lett 136:41–6
   PubMed Web of Science ®Google Scholar
• Dorr RT. (1991). Chemoprotectants for cancer chemotherapy. Semin Oncol 18:48–58
   PubMed Web of Science ®Google Scholar
• Draper HH, Hadley M. (1990). Malondialdehyde determination as an index of lipid peroxidation. Meth Enzymol 186:421–31
   PubMed Web of Science ®Google Scholar
• Dziegiel P, Surowiak P, Zabel M. (2002). Correlation of histopathological and biochemical appraisal of anthracyclin-induced myocardium damage. Folia Histochem Cytobiol 40:127–8
   PubMedGoogle Scholar
• Fatehi M, Rashidabady T, Fatehi-Hassanabad Z. (2003). Effects of Crocus sativus petal’s extract on rat blood pressure and on responses induced by electrical field stimulation in the rat isolated vas deferens and guinea-pig-ileum. J Ethnopharmacol 84:199–203
   PubMed Web of Science ®Google Scholar
• Hu ML. (2011). Dietary polyphenols as antioxidants and anticancer agents: More questions than answers. Chang Gung Med J 34:449–60
   PubMedGoogle Scholar
• Jensen BV, Skovsgaard T, Nielsen SL. (2002). Functional monitoring of anthracycline cardiotoxicity: A prospective, blinded, long-term observational study of outcome in 120 patients. Ann Oncol 13:699–709
   PubMed Web of Science ®Google Scholar
• Kang YJ, Chen Y, Epstein PN. (1996). Surexpression of doxorubicin cardiotoxicity by over-expression of catalase in the heart of transgenic mice. J Biol Chem 271:12610–16
   PubMed Web of Science ®Google Scholar
• Lecour S, Baouali AB, Maupoil V, et al. (1998). Demonstration of the production of oxygen-centered free radicals during electrolysis using E.S.R. spin-trapping techniques: Effects on cardiac function in the isolated rat heart. Free Radic Biol Med 24:573–9
   PubMedGoogle Scholar
• Lee V, Randhawa AK, Singal PK. (1991). Adriamycin-induced myocardial dysfunction in vitro is mediated by free radicals. Am J Physiol 261:H989–95
   PubMed Web of Science ®Google Scholar
• Makhlouf H, Saksouk M, Habib J, Chahine R. (2011). Determination of antioxidant activity of saffron taken from the flower of Crocus sativus grown in Lebanon. Afr J Biotechnol 10:8093–100
   Web of Science ®Google Scholar
• Mokni M, Hamlaoui-Guesmi S, Amri M, et al. (2012). Extract protects against acute chemotherapy toxicity induced by doxorubicin in rat heart. Cardiovasc Toxicol 24:84–99
   Google Scholar
• Molnar J, Szabo D, Pusztai R, et al. (2000). Membrane associated antitumor effects of crocin-, ginsenoide- and cannabinoid-derivatives. Anticancer Res 20:861–7
   PubMed Web of Science ®Google Scholar
• Nemr R, Lasserre B, Chahine R. (2003). Effects of nicotine on thromboxane/prostacyclin balance in myocardial ischemia. Prostaglandins Leukot Essent Fatty Acids 68:191–5
   PubMedGoogle Scholar
• Quiles JL, Huertas JR, Battino M, et al. (2002). Antioxidant nutrients and adriamycin toxicity. Toxicology 180:79–95
   PubMed Web of Science ®Google Scholar
• Sarvazyan N. (1996). Visualization of doxorubicin-induced oxidative stress in isolated cardiac myocytes. Am J Physiol 271:H2079–85
   PubMed Web of Science ®Google Scholar
• Shimpo K, Nagatsu T, Yamada K, et al. (1991). Ascorbic acid and adriamycin toxicity. Amer J Clin Nutr 54:1298S–301S
   Google Scholar
• Simůnek T, Stérba M, Popelová O, et al. (2009). Anthracycline-induced cardiotoxicity: Overview of studies examining the roles of oxidative stress and free cellular iron. Pharmacol Rep 61:154–71
   PubMed Web of Science ®Google Scholar
• Swain M, Whaley F, Ewer MS. (2003). Congestive heart failure in patients treated with doxorubicin. Cancer 97:2869–79
   PubMed Web of Science ®Google Scholar
• Tebbi CK, London WB, Friedman D, et al. (2007). Dexrazoxane-associated risk for acute myeloid leukemia/myelodysplastic syndrome and other secondary malignancies in pediatric Hodgkin’s disease. J Clin Oncol 25:493–500
   PubMed Web of Science ®Google Scholar
• Visioli F, De La Lastra CA, Andres-Lacueva C, et al. (2011). Polyphenols and human health: A prospectus. Crit Rev Food Sci Nutr 51:524–46
   PubMed Web of Science ®Google Scholar
• Volkova M, Russell R 3rd. (2011). Anthracycline cardiotoxicity: Prevalence, pathogenesis and treatment. Curr Cardiol Rev 7:214–20
   PubMedGoogle Scholar
• Wang S, Konorev EA, Kotamraju S, et al. (2004). Doxorubicin induces apoptosis in normal and tumor cells via distinctly different mechanisms. Intermediacy of H(2)O(2)- and p53-dependent pathways. J Biol Chem 279:25535–43
   PubMed Web of Science ®Google Scholar
• Wattanapitayakul SK, Chularojmontri L, Herunsalee A, et al. (2005). Screening of antioxidants from medicinal plants for cardioprotective effect against doxorubicin toxicity. Basic Clin Pharmacol Toxicol 96:80–7
   PubMed Web of Science ®Google Scholar
• Yalçin E, Oruç E, Cavuşoğlu K, Yapar K. (2010). Protective role of grape seed extract against doxorubicin-induced cardiotoxicity and genotoxicity in albino mice. J Med Food 13:917–25
   PubMed Web of Science ®Google Scholar
• Yen HC, Oberley TD, Vichitbandhas S, et al. (1996). The protective role of manganese superoxide dismutase against adriamycin-induced acute cardiac toxicity in transgenic mice. J Clin Invest 98:1253–60
   PubMed Web of Science ®Google Scholar
• Zhou S, Palmeira CM, Wallace KB. (2001). Doxorubicin-induced persistent oxidative stress to cardiac myocytes. Toxicol Lett 121:151–7
   PubMed Web of Science ®Google Scholar