6,632
Views
13
CrossRef citations to date
0
Altmetric
Original Article

Insight into the bronchodilator activity of Vitex negundo

, &
Pages 340-344 | Received 05 Nov 2013, Accepted 23 Apr 2014, Published online: 26 Jan 2015

References

  • Abdel-Latif AA. (2001). Cross talk between cyclic nucleotides and polyphosphoinositide hydrolysis, protein kinases, and contraction in smooth muscle. Exp Biol Med 226:153–63
  • Apaya KL, Chichioco-Hernandez CL. (2011). Xanthine oxidase inhibition of selected Philippine medicinal plants. J Med Plant Res 5:289–92
  • Au DT, Wu J, Jiang Z, et al. (2008). Ethnobotanical study of medicinal plants used by Hakka in Guangdong, China. J Ethnopharmacol 117:41–50
  • Avadhoot Y, Rana AC. (1991). Hepatoprotective effect of Vitex negundo against carbon tetrachloride-induced liver damage. Arch Pharm Res 14:96–8
  • Baquar SR. (1989). Medicinal and Poisonous Plants of Pakistan. Karachi, Pakistan: Printas
  • Bolton TB. (1979). Mechanism of action of transmitters and other substances on smooth muscles. Physiol Rev 59:606–718
  • Boselli C, Bianchi L, Barbieri A, Grana E. (1998). Effect of calcium antagonists on the response to noradrenaline in the whole and bisected rat vas deferens. J Auton Pharmacol 18:297–306
  • Boswell-Smith V, Spina D, Page CP. (2006). Phosphodiesterase inhibitors. Br J Pharmacol 47:S252–7
  • Dar A, Channa S. (1997). Bronchodilatory and cardiovascular effects of an ethanol extract of Bacopa monniera in anaesthetized rats. Phytomedicine 4:319–23
  • Das S, Parveen S, Kundra CP, Pereira BMJ. (2004). Reproduction in male rats is vulnerable to treatment with the flavonoid-rich seed extracts of Vitex negundo. Phytother Res 18:8–13
  • Dharmasiri MG, Jayakody JR, Galhena G, et al. (2003). Anti-inflammatory and analgesic activities of mature fresh leaves of Vitex negundo. J Ethnopharmacol 87:199–206
  • Diaz F, Chavez D, Lee D, et al. (2003). Cytotoxic flavone analogues of vitexicarpin, a constituent of the leaves of Vitex negundo. J Nat Prod 66:865–7
  • Edwards MR, Bartlett NW, Hussell T, et al. (2012). The microbiology of asthma. Nat Rev Microbiol 10:459–71
  • Evans WC. (2006). Trease and Evans Pharmacognosy. London, England: WB Saunders
  • Gautam LN, Shrestha SL, Wagle P, Tamrakar BM. (2008). Chemical constituents from Vitex negundo (Linn.) of Nepalese origin. Sci World 6:27–32
  • Gilani AH, Khan A, Ali T, Ajmal S. (2008). Mechanisms underlying the antispasmodic and bronchodilatory properties of Terminalia bellerica fruit. J Ethnopharmacol 116:528–38
  • Godfraind T, Miller R, Wibo M. (1986). Calcium antagonism and calcium entry blockade. Pharmacol Rev 38:321–416
  • Gupta M, Mazumder UK, Bhawal SR. (1999). CNS activity of Vitex negundo Linn. in mice. Indian J Exp Biol 37:143–6
  • Halayko AJ, Tran T, Ji SY, et al. (2006). Airway smooth muscle phenotype and function: Interactions with current asthma therapies. Curr Drug Targets 7:525–40
  • Khan AU, Gilani AH. (2009). Antispasmodic and bronchodilator activities of Artemisia vulgaris are mediated through dual blockade of muscarinic receptors and calcium influx. J Ethnopharmacol 126:480–6
  • Khan M, Arif UK, Najeeb UR, Gilani AH. (2011). Pharmacological explanation for the medicinal use of Juniperus excelsa in hyperactive gastrointestinal and respiratory disorders. J Nat Med 66:292–301
  • Khan M, Arif UK, Najeeb UR, Gilani AH. (2012). Gut and airways relaxant effects of Carum roxburghianum. J Ethnopharmacol 141:938–46
  • Khan M, Shah AJ, Gilani AH. (2013). Antidiarrheal and antispasmodic activities of Vitex negundo are mediated through calcium channel blockade. Bangladesh J Pharmacol 8:317–22
  • Kai L, Wang ZF, Xiao JS. (1998). L-Type calcium channel blockade mechanisms of panaxadiol saponins against anoxic damage of cerebral cortical neurons isolated from rats. Zhongguo Yao Li Xue Bao 19:455–8
  • Ko WC, Shih CM, Lai YH, et al. (2004). Inhibitory effects of flavonoids on phosphodiesterase isozymes from guinea pig and their structure–activity relationships. Biochem Pharmacol 68:2087–94
  • Lorenz KL, Wells JN. (1983). Potentiation of the effect of sodium nitroprosside and isoproterenol by selective phosphodiesterase inhibitors. Mol Pharmacol 23:424–30
  • Moran A, Carron R, Martin ML, Roman LS. (1989). Antiasthmatic activity of Artemisia caerulescens subsp. gallica. Planta Med 55:351–3
  • Munasinghe JTC, Seneviratne CK, Thabrew MI, Abeysekera AM. (2001). Antiradical and antilipoperoxidative effects of some plant extracts used by Sri Lankan traditional medical practitioners for cardioprotection. Phytother Res 15:519–23
  • Nair AM, Saraf MN. (2005). Inhibition of antigen and compound 48/80 induced contractions of guinea-pig trachea by the ethanolic extract of the leaves of Vitex negundo Linn. Indian J Pharmacol 27:230–3
  • National Research Council. (1996). Guide for the Care and Use of Laboratory Animals. Washington, DC: National Academy Press
  • Patel J, Shah S, Deshpande S, Shah G. (2009). Evaluation of the antiasthmatic activity of leaves of Vitex negundo. Asian J Pharm Clin Res 2:81–6
  • Patel MD, Patel MA, Shah GB. (2010). Evaluation of the effect of Vitex nigundo leaves extract on bronchoconstriction and bronchial hyperreactivity in experimental animals. Pharmacologyonline 1:644–54
  • Perumal-Samy R, Ignacimuthu S, Sen A. (1998). Screening of 34 Indian medicinal plants for antibacterial properties. J Ethnopharmacol 62:173–82
  • Puchpangadan P, Chandana VR, Govindarajan R, et al. (2006). Anti-arthritic herbal composition and method thereof. Available from: http://www.freepatentsonline.com/20060141061.html [last accessed 22 Jan 2014]
  • Raeburn J, Souness JE, Tomkinson A, Karlsson JA. (1993). Isoenzyme-selective cyclic nucleotide phosphodiesterase inhibitors: Biochemistry, pharmacology and therapeutic potential in asthma. Prog Drug Res 40:9–32
  • Shah AJ, Gilani AH. (2010). Bronchodilatory effect of Acorus calamus and its constituents is mediated through inhibition of phosphodiesterases, calcium channel and muscarinic receptors. J Ethnopharmacol 131:471–7
  • Tandon VR. (2005). Medicinal uses and biological activities of Vitex negundo. Nat Prod Res 4:162–5
  • Tandon VR, Gupta RK. (2006). Vitex negundo Linn (VN) leaf extract as an adjuvant therapy to standard anti-inflammatory drugs. Indian J Med Res 124:447–50
  • Yan B, Michael JS. (2006). Airway smooth muscle relaxation results from a reduction in the frequency of Ca++ oscillations induced by a cAMP-mediated inhibition of the IP3 receptor. Respir Res 7:1–20
  • Zheng CJ, Lan XP, Wang Y, et al. (2012). A new labdanediterpene from Vitex negundo. Pharm Biol 50:687–90

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.