Ferulic acid pretreatment mitigates MPTP-induced motor impairment and histopathological alterations in C57BL/6 mice

References

• Ardiansyah A, Ohsaki Y, Shirakawa H, et al. (2008). Novel effects of a single administration of ferulic acid on the regulation of blood pressure and the hepatic lipid metabolic profile in stroke-prone spontaneously hypertensive rats. J Agric Food Chem 56:2825–30
   PubMed Web of Science ®Google Scholar
• Benetti F, Gustincich S, Legname G. (2012). Gene expression profiling and therapeutic interventions in neurodegenerative diseases: A comprehensive study on potentiality and limits. Expert Opin Drug Discov 7:245–59
   PubMed Web of Science ®Google Scholar
• Brown RE, Corey SC, Moore AK. (1999). Differences in measures of exploration and fear in MHC-congenic C57BL/6J and B6-H-2K mice. Behav Genet 29:263–71
   Web of Science ®Google Scholar
• Chung YC, Kim SR, Park JY, et al. (2011). Fluoxetine prevents MPTP-induced loss of dopaminergic neurons by inhibiting microglial activation. Neuropharmacology 60:963–74
   Google Scholar
• Cryan JF, Valentino RJ, Lucki I. (2005). Assessing substrates underlying the behavioral effects of antidepressants using the modified rat forced swimming test. Neurosci Biobehav Rev 29:547–69
   PubMed Web of Science ®Google Scholar
• Dauer W, Przedborski S. (2003). Parkinson's disease: Mechanisms and models. Neuron 39:889–909
   PubMed Web of Science ®Google Scholar
• Fahn S. (2003). Description of Parkinson's disease as a clinical syndrome. Ann N Y Acad Sci 991:1–14
   PubMed Web of Science ®Google Scholar
• Ferré S, Guix T, Prat G, et al. (1990). Is experimental catalepsy properly measured? Pharmacol Biochem Behav 35:753–7
   PubMed Web of Science ®Google Scholar
• Gao HM, Jiang J, Wilson B, et al. (2002). Microglial activation-mediated delayed and progressive degeneration of rat nigral dopaminergic neurons: Relevance to Parkinson's disease. J Neurochem 81:1285–97
   PubMed Web of Science ®Google Scholar
• Gould TD, Dao DT, Kovacsics CE. (2009). The open field test. In: Gould TD, ed. Mood and Anxiety Related Phenotypes in Mice. Neuromethods. New York: Humana Press, 1–20
   Google Scholar
• Haschek WM, Rousseaux CG, Wallig WA. (2009). Fundamentals of Toxicologic Pathology, 2nd ed. San Diego: Academic Press
   Google Scholar
• Horowitz JM, Pastor DM, Goyal A, et al. (2003). BAX protein-immunoreactivity in midbrain neurons of Parkinson's disease patients. Brain Res Bull 62:55–61
   PubMed Web of Science ®Google Scholar
• Jackson-Lewis V, Przedborski S. (2007). Protocol for the MPTP mouse model of Parkinson's disease. Nat Protoc 2:141–51
   PubMed Web of Science ®Google Scholar
• Joseph JA, Bartus RT, Clody DE. (2005). Reversing the deleterious effects of aging on neuronal communication and behavior: Beneficial properties of fruit polyphenolic compounds. Am J Clin Nutr 81:313S–16
   PubMed Web of Science ®Google Scholar
• Khan MM, Hoda MN, Ishrat T, et al. (2010). Amelioration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced behavioural dysfunction and oxidative stress by Pycnogenol in mouse model of Parkinson's disease. Behav Pharmacol 21:563–71
   PubMed Web of Science ®Google Scholar
• Khuwaja G, Khan MM, Ishrat T, et al. (2011). Neuroprotective effects of curcumin on 6-hydroxydopamine-induced Parkinsonism in rats: Behavioral, neurochemical and immunohistochemical studies. Brain Res 1368:254–63
   PubMed Web of Science ®Google Scholar
• Kim HS, Cho JY, Kim DH, et al. (2004). Inhibitory effects of long-term administration of ferulic acid on microglial activation induced by intracerebroventricular injection of beta-amyloid peptide (1-42) in mice. Biol Pharm Bull 27:120–1
   PubMed Web of Science ®Google Scholar
• Liu RH. (2003). Health benefits of fruit and vegetables are from additive and synergistic combinations of phytochemicals. Am J Clin Nutr 78:517S–20
   PubMed Web of Science ®Google Scholar
• Lucki I. (1997). The forced swimming test as a model for core and component behavioral effects of antidepressant drugs. Behav Pharmacol 8:523–32
   PubMed Web of Science ®Google Scholar
• Luo Y, Zhao HP, Zhang J, et al. (2012). Effect of ferulic acid on learning and memory impairments of vascular dementia rats and its mechanism of action. Yao Xue Xue Bao 47:256–60
   PubMedGoogle Scholar
• Mamiya T, Kise M, Morikawa K. (2008). Ferulic acid attenuated cognitive deficits and increase in carbonyl proteins induced by buthionine-sulfoximine in mice. Neurosci Lett 430:115–18
   PubMed Web of Science ®Google Scholar
• Mancuso C, Santangelo R. (2014). Ferulic acid: Pharmacological and toxicological aspects. Food Chem Toxicol 65:185–95
   PubMed Web of Science ®Google Scholar
• Martínez-Banaclocha MA. (2012). N-acetyl-cysteine in the treatment of Parkinson's disease. What are we waiting for? Med Hypotheses 79:8–12
   Google Scholar
• Matsuura K, Kabuto H, Makino H, Ogawa N. (1997). Pole test is a useful method for evaluating the mouse movement disorder caused by striatal dopamine depletion. J Neurosci Methods 73:45–8
   PubMed Web of Science ®Google Scholar
• Moon M, Kim HG, Hwang L, et al. (2009). Neuroprotective effect of ghrelin in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease by blocking microglial activation. Neurotox Res 15:332–47
   PubMed Web of Science ®Google Scholar
• Nakamura K, Bindokas VP, Marks JD, et al. (2000). The selective toxicity of 1-methyl-4-phenylpyridinium to dopaminergic neurons: The role of mitochondrial complex I and reactive oxygen species revisited. Mol Pharmacol 58:271–8
   PubMed Web of Science ®Google Scholar
• Ogawa N, Hirose Y, Ohara S, et al. (1985). A simple quantitative bradykinesia test in MPTP-treated mice. Res Commun Chem Pathol Pharmacol 50:435–41
   PubMedGoogle Scholar
• Porsolt RD, Bertin A, Jalfre M. (1977). Behavioral despair in mice: A primary screening test for antidepressants. Arch Int Pharmacodyn Ther 229:327–36
   PubMedGoogle Scholar
• Pothakos K, Kurz MJ, Lau YS. (2009). Restorative effect of endurance exercise on behavioral deficits in the chronic mouse model of Parkinson's disease with severe neurodegeneration. BMC Neurosci 10:6
   PubMedGoogle Scholar
• Prabhakar PK, Prasad R, Ali S, Doble M. (2013). Synergistic interaction of ferulic acid with commercial hypoglycemic drugs in streptozotocin induced diabetic rats. Phytomedicine 20:488–94
   Google Scholar
• Rappold PM, Tieu K. (2010). Astrocytes and therapeutics for Parkinson's disease. Neurotherapeutics 7:413–23
   PubMed Web of Science ®Google Scholar
• Rozas G, López-Martín E, Guerra MJ, Labandeira-García JL. (1998). The overall rod performance test in the MPTP-treated-mouse model of Parkinsonism. J Neurosci Methods 83:165–75
   PubMed Web of Science ®Google Scholar
• Sedelis M, Schwarting RK, Huston JP. (2001). Behavioral phenotyping of the MPTP mouse model of Parkinson's disease. Behav Brain Res 125:109–25
   PubMed Web of Science ®Google Scholar
• Singh S, Singh K, Patel DK, et al. (2009). The expression of CYP2D22, an ortholog of human CYP2D6, in mouse striatum and its modulation in 1-methyl 4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease phenotype and nicotine-mediated neuroprotection. Rejuvenation Res 12:185–97
   PubMed Web of Science ®Google Scholar
• Stachowiak MK, Bruno JP, Snyder AM, et al. (1984). Apparent sprouting of striatal serotonergic terminals after dopamine-depleting brain lesions in neonatal rats. Brain Res 291:164–7
   Google Scholar
• Stefanis L. (2012). α-Synuclein in Parkinson's disease. Cold Spring Harb Perspect Med 2:a009399
   PubMed Web of Science ®Google Scholar
• Sultana R. (2012). Ferulic acid ethyl ester as a potential therapy in neurodegenerative disorders. Biochim Biophys Acta 1822:748–52
   PubMed Web of Science ®Google Scholar
• Trombino S, Cassano R, Ferrarelli T, et al. (2013). Trans-ferulic acid-based solid lipid nanoparticles and their antioxidant effect in rat brain microsomes. Colloids Surf B Biointerfaces 109:273–9
   PubMed Web of Science ®Google Scholar
• Varçin M, Bentea E, Michotte Y, Sarre S. (2012). Oxidative stress in genetic mouse models of Parkinson's disease. Oxid Med Cell Longev 2012:624925
   Google Scholar
• Wu DC, Teismann P, Tieu K, et al. (2003). NADPH oxidase mediates oxidative stress in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease. Proc Natl Acad Sci USA 100:6145–50
   PubMed Web of Science ®Google Scholar
• Yan JJ, Jung JS, Kim TK, et al. (2013). Protective effects of ferulic acid in amyloid precursor protein plus presenilin-1 transgenic mouse model of Alzheimer disease. Biol Pharm Bull 36:140–3
   PubMed Web of Science ®Google Scholar
• Yang F, Zhou BR, Zhang P, et al. (2007). Binding of ferulic acid to cytochrome c enhances stability of the protein at physiological pH and inhibits cytochrome c-induced apoptosis. Chem Biol Interact 170:231–43
   PubMed Web of Science ®Google Scholar
• Yasuda T, Nakata Y, Mochizuki H. (2013). α-Synuclein and neuronal cell death. Mol Neurobiol 47:466–83
   PubMed Web of Science ®Google Scholar
• Zeni AL, Zomkowski AD, Maraschin M, et al. (2012). Ferulic acid exerts antidepressant-like effect in the tail suspension test in mice: Evidence for the involvement of the serotonergic system. Eur J Pharmacol 679:68–74
   PubMed Web of Science ®Google Scholar