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Pharmaceutical Biology Volume 54, 2016 - Issue 6
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Research Article

Antiproliferative effect of extracts and pyranonaphthoquinones obtained from Cipura paludosa bulbs

Adriana Campos1 Programa De Pós-Graduação Em Ciências Farmacêuticas and Núcleo De Investigações Químico-Farmacêuticas (NIQFAR), Universidade Do Vale Do Itajaí – UNIVALI, Itajaí, Santa Catarina, Brazil, Correspondence[email protected]
,
Débora Barbosa Vendramini-Costa2 Centro Pluridisciplinar De Pesquisas Químicas, Biológicas E Agrícolas (CPQBA) – Universidade Estadual De Campinas (UNICAMP), Campinas, São Paulo, Brazil, and
,
Giovanna Francisco Fiorito2 Centro Pluridisciplinar De Pesquisas Químicas, Biológicas E Agrícolas (CPQBA) – Universidade Estadual De Campinas (UNICAMP), Campinas, São Paulo, Brazil, and
,
Ana Lúcia Tasca Gois Ruiz2 Centro Pluridisciplinar De Pesquisas Químicas, Biológicas E Agrícolas (CPQBA) – Universidade Estadual De Campinas (UNICAMP), Campinas, São Paulo, Brazil, and
,
João Ernesto de Carvalho2 Centro Pluridisciplinar De Pesquisas Químicas, Biológicas E Agrícolas (CPQBA) – Universidade Estadual De Campinas (UNICAMP), Campinas, São Paulo, Brazil, and
,
Greice Maria Rodrigues de Souza3 Núcleo Da Saúde – Centro Universitário Euro-Americano (UNIEURO), Brasília-DF, Brazil
,
Franco Delle-Monache1 Programa De Pós-Graduação Em Ciências Farmacêuticas and Núcleo De Investigações Químico-Farmacêuticas (NIQFAR), Universidade Do Vale Do Itajaí – UNIVALI, Itajaí, Santa Catarina, Brazil,
&
Valdir Cechinel Filho1 Programa De Pós-Graduação Em Ciências Farmacêuticas and Núcleo De Investigações Químico-Farmacêuticas (NIQFAR), Universidade Do Vale Do Itajaí – UNIVALI, Itajaí, Santa Catarina, Brazil,
show all
Pages 1022-1026 | Received 01 Jun 2015, Accepted 04 Sep 2015, Published online: 15 Oct 2015

References

  • Alves TM, Kloos H, Zani CL. 2003. Eleutherinone, a novel fungitoxic naphthoquinone from Eleutherine bulbosa (Iridaceae). Mem Inst Oswaldo Cruz. 98:709–712.
  • Bhasin D, Chettiar SN, Etter JP, Mok M, Li PK. 2013. Anticancer activity and SAR studies of substituted 1,4-naphthoquinones. Bioorg Med Chem. 21:4662–4669.
  • Cragg GM, Grothaus PG, Newman DJ. 2014. New horizons for old drugs and drug leads. J Nat Prod. 77:703–723.
  • Cragg GM, Newman DJ. 2013. Natural products: a continuing source of novel drug leads. Biochim Biophys Acta 1830:3670–3695.
  • Duchowicz PR, Bennardi DO, Bacelo DE, Bonifazi EL, Rios-Luci C, Padrón JM, Burton G, Misico RI. 2014. QSAR on antiproliferative naphthoquinones based on a conformation-independent approach. Eur J Med Chem. 77:176–184.
  • Fouche G, Cragg GM, Pillay P, Kolesnikova N, Maharaj VJ, Senabe J. 2008. In vitro anticancer screening of South African plants. J Ethnopharmacol. 119:455–461.
  • Gallo FR, Palazzino G, Federici E, Iurilli R, Galeffi C, Chifundera K, Nicoletti M. 2010. Polyketides from Eleutherine bulbosa. Nat Prod Res. 24:1578–1586.
  • Hara H, Maruyama N, Yamashita S, Hayashi Y, Lee KH, Bastow KF, Chairul RM, Imakura Y. 1997. Elecanacin, a novel new naphthoquinone from the bulb of Eleutherine americana. Chem Pharm Bull. 45:1714–1716.
  • Hogen Esch H, Nikitin AY. 2012. Challenges in pre-clinical testing of anti-cancer drugs in cell culture and in animal models. J Control Release. 164:183–186.
  • Hong JH, Yu ES, Han AR, Nam JW, Seo EK, Hwang ES. 2008. Isoeleutherin and eleutherinol, naturally occurring selective modulators of Th cell-mediated immune responses. Biochem Biophys Res Commun. 371:278–282.
  • Kayashima T, Mori M, Yoshida H, Mizushina Y, Matsubara K. 2009. 1,4-Naphthoquinone is a potent inhibitor of human cancer cell growth and angiogenesis. Cancer Lett. 278:34–40.
  • Kusuma IW, Arung ET, Rosamah E, Purwatiningsih S, Kuspradini H, Syafrizal, Astuti J, Kim YU, Shimizu K. 2010. Antidermatophyte and antimelanogenesis compound from Eleutherine americana grown in Indonesia. J Nat Med. 64:223–226.
  • Lin J, Puckree T, Mvelase TP. 2002. Anti-diarrhoeal evaluation of some medicinal plants used by Zulu traditional healers. J Ethnopharmacol. 79:53–56.
  • Lucena GM, Gadotti VM, Maffi LC, Silva GS, Azevedo MS, Santos AR. 2007. Antinociceptive and anti-inflammatory properties from the bulbs of Cipura paludosa Aubl. J Ethnopharmacol. 112:19–25.
  • Lucena GM, Matheus FC, Ferreira VM, Tessele PB, Azevedo MS, Cechinel-Filho V, Prediger RD. 2013. Effects of ethanolic extract and naphthoquinones obtained from the bulbs of Cipura paludosa on short-term and long-term memory: involvement of adenosine A1 and A2A receptors. Basic Clin Pharmacol Toxicol. 112:229–235.
  • Lucena GM, Porto FA, Campos EG, Azevedo MS, Cechinel-Filho V, Prediger RD, Ferreira VM. 2010. Cipura paludosa attenuates long-term behavioral deficits in rats exposed to methylmercury during early development. Ecotoxicol Environ Saf. 73:1150–1158.
  • Monks A, Scudiero D, Skehan P, Shoemaker R, Paull K, Vistica D, Hose C, Langley J, Cronise P, Vaigro-Wolff A, et al. 1991. Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines. J Natl Cancer Inst. 83:757–766.
  • Schultes RE, Raffauf RF. 1990. The healing forest: medicinal and toxic plants of the Northwest Amazonia. Portland, US: Dioscorides Press.
  • Shoemaker RH. 2006. The NCI60 human tumour cell line anticancer drug screen. Nat Rev Cancer. 6:813–823.
  • Silva Neto JAP, Menezes LD, Gomes GO, Cunha EMF, Azevedo MS, Ferreira VM, Da Silva MV 2014. Evaluation of antinociceptive and anti-inflammatory activities of the topical preparation of Cipura paludosa (Iridaceae). Acta Amaz. 44:263–270.
  • Tessele PB, Delle Monache F, Quintão NLM, Da Silva GF, Rocha LW, Lucena GM, Ferreira VM, Prediger RD, Cechinel-Filho V 2011. A new naphthoquinone isolated from the bulbs of Cipura paludosa and pharmacological activity of two main constituents. Planta Med. 77:1035–1043.
  • Weniger B, Haag-Berrurier M, Anton R. 1982. Plants of Haiti used as antifertility agents. J Ethnopharmacol. 6:67–84.

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