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Modern Rheumatology Volume 24, 2014 - Issue 6
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Letters

Dramatic radiographic repair by tocilizumab in a very elderly patient with rheumatoid arthritis

Ryu WatanabeDepartment of Hematology and Rheumatology, Tohoku University Graduate School of Medicine, Sendai, Japan
,
Yasuhiko HirabayashiDepartment of Rheumatology, Hikarigaoka Spellman Hospital, Sendai, Japan
,
Hiroshi OkunoDepartment of Orthopaedic Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan
,
Tomonori IshiiDepartment of Hematology and Rheumatology, Tohoku University Graduate School of Medicine, Sendai, Japan
&
Hideo HarigaeDepartment of Hematology and Rheumatology, Tohoku University Graduate School of Medicine, Sendai, Japan
Pages 1028-1029 | Received 15 May 2013, Accepted 17 Jul 2013, Published online: 21 Oct 2013

References

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  • Hirabayashi Y. The role of tocilizumab in the treatment of rheumatoid arthritis. In: Lemmey AB, editor. Rheumatoid Arthritis – Treatment. Rijeka, Croatia: InTech Open Access Company; 2011, pp. 51–70.
  • Smolen JS, Avila JCM, Aletaha D. Tocilizumab inhibits progression of joint damage in rheumatoid arthritis irrespective of its anti-inflammatory effects: disassociation of the link between inflammation and destruction. Ann Rheum Dis. 2012;71(5):687–93.
  • Hirabayashi Y, Ishii T, Harigae H. Clinical efficacy of tocilizumab in patients with active rheumatoid arthritis in real clinical practice. Rheumatol Int. 2010;30(8):1041–8.
  • Lukas C, van der Heijde D, Fatenajad S, Landewe R. Repair of erosions occurs almost exclusively in damaged joints without swelling. Ann Rheum Dis. 2010;69(5):851–5.
  • van der Linden MP, Boja R, Klarenbeek NB, Huizinga TW, van der Heijde D, van der Helm-van Mil AH. Repair of joint erosions in rheumatoid arthritis: prevalence and patient characteristics in a large inception cohort. Ann Rheum Dis. 2010;69(4):727–9.
  • Matzelle MM, Gallant MA, Condon KW, Walsh NC, Manning CA, Stein GS, et al. Resolution of inflammation induces osteoblast function and regulates the Wnt signaling pathway. Arthritis Rheum. 2012;64(5):1540–50.
  • Turkcapar N, Demir O, Atli T, Kopuk M, Turgay M, Kinikli G, et al. Late onset rheumatoid arthritis: clinical and laboratory comparisons with younger onset patients. Arch Gerontol Geriatr. 2006;42(2):225–31.
  • van Schaardenburg D, Breedveld FC. Elderly-onset rheumatoid arthritis. Semin Arthritis Rheum. 1994;23(6):367–78.
  • Villa-Blance JI, Calvo-Alen J. Elderly onset rheumatoid arthritis. Drugs Aging. 2009;26(9):739–50.
  • Calvo-Alen J, Corrales A, Sanchez-Andrada S, Fernadez-Echevarria MA, Pena JL, Rodriguez-Valverde V. Outcome of late-onset rheumatoid arthritis. Clin Rheumatol. 2005;24(5):485–9.
  • Hirabayashi Y, Ishii T; Michinoku Tocilizumab Study Group. The DAS28-ESR cutoff value necessary to achieve remission under the new Boolean-based remission criteria in patients receiving tocilizumab. Clin Rheumatol. 2013;32(1):123–7.

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