24
Views
1
CrossRef citations to date
0
Altmetric
Research Article

Early lymphocyte reconstitution is associated with improved transplant outcome after cord blood transplantation

, , , , , , , , , , & show all
Pages 78-82 | Received 06 Mar 2010, Accepted 17 May 2010, Published online: 30 Jun 2010

References

  • Wagner JE, Gluckman E. Umbilical cord blood transplantation: the first 20 years. Semin Hematol. 2010;47:3–12.
  • Le Blanc K, Barrett AJ, Schaffer M, Hagglund H, Ljungman P, Ringden O, . Lymphocyte recovery is a major determinant of outcome after matched unrelated myeloablative transplantation for myelogenous malignancies. Biol Blood Marrow Transplant. 2009;15:1108–15.
  • Powles R, Singhal S, Treleaven J, Kulkarni S, Horton C, Mehta J. Identification of patients who may benefit from prophylactic immunotherapy after bone marrow transplantation for acute myeloid leukemia on the basis of lymphocyte recovery early after transplantation. Blood. 1998;91: 3481–6.
  • Savani BN, Mielke S, Rezvani K, Montero A, Yong AS, Wish L, . Absolute lymphocyte count on day 30 is a surrogate for robust hematopoietic recovery and strongly predicts outcome after T cell-depleted allogeneic stem cell transplantation. Biol Blood Marrow Transplant. 2007;13: 1216–23.
  • Jiang YZ, Barrett AJ, Goldman JM, Mavroudis DA. Association of natural killer cell immune recovery with a graft-versus-leukemia effect independent of graft-versus-host disease following allogeneic bone marrow transplantation. Ann Hematol. 1997;74:1–6.
  • Sconocchia G, del Principe D, Barrett AJ. Non-classical antileukemia activity of early recovering NK cells after induction chemotherapy and HLA-identical stem cell transplantation in myeloid leukemias. Leukemia. 2006;20:1632–3.
  • Niederwieser D, Gastl G, Rumpold H, Marth C, Kraft D, Huber C. Rapid reappearance of large granular lymphocytes (LGL) with concomitant reconstitution of natural killer (NK) activity after human bone marrow transplantation (BMT). Br J Haematol. 1987;65:301–5.
  • Savani BN, Mielke S, Adams S, Uribe M, Rezvani K, Yong AS, . Rapid natural killer cell recovery determines outcome after T-cell-depleted HLA-identical stem cell transplantation in patients with myeloid leukemias but not with acute lymphoblastic leukemia. Leukemia. 2007;21:2145–52.
  • Barker JN, Weisdorf DJ, DeFor TE, Blazar BR, Miller JS, Wagner JE. Rapid and complete donor chimerism in adult recipients of unrelated donor umbilical cord blood transplantation after reduced-intensity conditioning. Blood. 2003;102: 1915–19.
  • Behl D, Porrata LF, Markovic SN, Letendre L, Pruthi RK, Hook CC, . Absolute lymphocyte count recovery after induction chemotherapy predicts superior survival in acute myelogenous leukemia. Leukemia. 2006;20:29–34.
  • Porrata LF, Inwards DJ, Ansell SM, Micallef IN, Johnston PB, Gastineau DA, . Early lymphocyte recovery predicts superior survival after autologous stem cell transplantation in non-Hodgkin lymphoma: a prospective study. Biol Blood Marrow Transplant. 2008;14:807–16.
  • Barrett AJ, Savani BN. Does chemotherapy modify the immune surveillance of hematological malignancies? Leukemia. 2009;23:53–8.
  • Savani BN, Rezvani K, Mielke S, Montero A, Kurlander R, Carter CS, . Factors associated with early molecular remission after T cell-depleted allogeneic stem cell transplantation for chronic myelogenous leukemia. Blood. 2006;107: 1688–95.
  • Rodrigues CA, Canals C Sr., Brunstein C, Finke J, Nagler A, Maertens J, . Comparison of outcomes after unrelated cord blood transplantation and matched unrelated donor RIC transplantation for lymphoid malignancies. A Eurocord-Netcord Group/Lymphoma Working Party and Chronic Leukemia Working Party of the European Group for Blood and Marrow Transplantation Study. ASH Annual Meeting Abstracts. 2009;114:663.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.