123
Views
4
CrossRef citations to date
0
Altmetric
Research Article

Human platelet lysate permits scale-up of dental pulp stromal cells for clinical applications

, , , , , , , , & show all
Pages 1221-1233 | Received 03 Sep 2010, Accepted 27 Jun 2011, Published online: 20 Sep 2011

References

  • d'Aquino R, De Rosa A, Lanza V, Tirino V, Laino L, Graziano A, . Human mandible bone defect repair by the grafting of dental pulp stem/progenitor cells and collagen sponge biocomplexes. Eur Cells Mater. 2009;18:75–83.
  • Jo YY, Lee HJ, Kook SY, Choung HW, Park JY, Chung JH, . Isolation and characterization of postnatal stem cells from human dental tissues. Tissue Eng. 2007;13:767–73.
  • Lensch MW, Daheron L, Schlaeger TM. Pluripotent stem cells and their niches. Stem Cell Rev. 2006;2:185–201.
  • Iohara K, Zheng L, Ito M, Tomokiyo A, Matsushita K, Nakashima M. Side population cells isolated from porcine dental pulp tissue with self-renewal and multipotency for dentinogenesis, chondrogenesis, adipogenesis, and neurogenesis. Stem Cells. 2006;24:2493–503.
  • Sakai VT, Zhang Z, Dong Z, Neiva KG, Machado MA, Santos CF, . SHED differentiate into functional odontoblasts and endothelium. J Dent Res. 2010;89:791–6.
  • Ishkitiew N, Yegaki K, Calenic B, Nakahara T, Ishikawa H, Mitiew V, . Deciduous and permanent dental pulp mesenchymal cells acquire hepatic morphologic and functional features in vitro. J Endod. 2010;36:469–74.
  • Govindasamy V, Ronald VS, Abdullah AN, Ganesan Nathan KR, Ab Aziz ZA, Abdullah M, . Differentiation of dental pulp stem cells into islet like aggregates. J Den Res. 2011;90:646–52.
  • Gandia C, Arminan A, Garcia-Verdugo JM, Lledo E, Ruiz A, Minana MD, . Human dental pulp stem cells improve left ventricular function, induce angiogenesis, and reduce infarct size in rats with acute myocardial infarction. Stem Cells. 2008;26:638–45.
  • Wang J, Wang X, Sun Z, Wang X, Yang H, Shi S, . Stem cells from human exfoliated deciduous teeth can differentiate into dopaminergic neuron-like cells. Stem Cells Dev. 2009; 19:1375–83.
  • Hon KV, Singley JA, Chavin W. Fetal bovine serum: a multivariate standard. Proc Soc Exp Bio Med. 1975;149:344–7.
  • Sundin M, Ringden O, Sundberg B, Nava S, Gotherstrom C, Le Black K. No alloantibodies against mesenchymal stromal cells, but presence of anti-fetal calf serum anti-bodies after transplantation in allogeneic hematopoietic stem cells recipients. Haematologica. 2007;92:1208–1215.
  • Manello F, Tonti GA. Concise review. No breakthroughs for human mesenchymal and embryonic stem cell culture: conditioned medium, feeder layer, or feeder-free; medium with fetal calf serum, human serum, or enriched plasma; serum-free, serum replacement nonconditioned medium, or ad hoc formula? All that glitters is not gold! Stem Cells. 2007;25:1603–9.
  • Schallmoser K, Bartmann C, Rohde E, Reinisch A, Kashofer K, Stadelmever E, . Human platelet lysate can replace fetal bovine serum for clinical-scale expansion of functional mesenchymal stromal cells. Transfusion. 2007;47: 1436–46.
  • Schallmoser K, Rohde E, Reinisch A, Bartmann C, Thaler D, Drexler C, . Rapid large-scale expansion of functional mesenchymal stem cells from unmanipulated bone marrow without animal serum. Tissue Eng Part C Methods. 2008; 14:185–96.
  • Stute N, Holtz K, Bubenheim M, Lange C, Blake F, Zander AR. Autologous serum for isolation and expansion of human mesenchymal stem cells for clinical use. Exp Hematol. 2004; 32:1212–25.
  • Oreffo RO, Virdi AS, Triffitt JT. Modulation of osteogenesis and adipogenesis by human serum in human bone marrow cultures. Eur J Cell Biol. 1997;74:251–61.
  • Janetzko K, Kluter H, Waeg GV, Eichler H. Fully automated processing of buffy-coat-derived pooled platelet concentrates. Transfusion. 2004;44:1052–8.
  • Chevallier N, Anagnostou F, Zilber S, Bodivit G, Maurin S, Barrault A, . Osteoblastic differentiation of human mesenchymal stem cells with platelet lysate. Biomaterials. 2009:270–8.
  • Harrison P, Cramer EM. Platelet alpha-granules. Blood Rev. 1993;7:52–62.
  • Govindasamy V, Ronald VS, Totey S, Din S, Wan Mustafa WM, Totey S, . Micromanipulation of culture niche permits long term expansion of dental pulp stem cells: an economic and commercial angle. J In Vitro Cell Dev Biol Anim. 2010;46:764–73.
  • Pal R, Hanwate M, Jan M, Totey S. Phenotypic and functional comparison of optimum culture condition for upscaling of bone marrow derived mesenchymal stem cells. J Tissue Eng Regen Med. 2009;3:163–74.
  • Sotiropoulou PA, Perez SA, Salagianni M, Baxevanis CN, Papamichail M. Characterization of the optimal culture conditions for clinical scale production of human mesenchymal stem cells. Stem Cells. 2006;24:462–71.
  • Purpura KA, Aubin JE, Zandstra PW. Two-color image analysis discriminates between mineralized and unmineralized bone nodules in vitro. BioTechniques. 2003;34:1188–98.
  • Dominici M, Le Blanc K, Mueller I, Slapper-Cortenbach I, Marini F, Krause D, . Minimal criteria for defining multipotent mesenchymal stromal cells: the International Society for Cellular Therapy position statement. Cytotherapy. 2006;8:315–17.
  • Vescovi AL, Reynolds BA, Fraser DD, Weiss S. BFGF regulates the proliferative fate of unipotent (neuronal) and bipotent (neuronal/astroglial) EFG-generated CNS progenitor cells. Neuron. 1993;11:951–66.
  • Nekanti U, Rao VB, Bahirvani AG, Jan M, Totey S, Ta M. Long-term expansion and pluripotent marker array analysis of Wharton's jelly-derived mesenchymal stem cells. Stem Cells Dev. 2010;19:117–30.
  • Bartmann C, Rohde E, Schallmoser K, Pürstner P, Lanzer G, Linkesch W, . Two steps to functional mesenchymal stromal cells for clinical application. Transfusion. 2007;47:1426–35.
  • Bieback K, Hecker A, Kocaomer A, Lannert H, Schallmoser K, Strunk D, . Human alternatives to fetal bovine serum for the expansion of mesenchymal stromal cells from bone marrow. Stem Cells. 2009;27:2331–41.
  • Carrancio S, Lopez-Holgado N, Sanchez-Guijo FM, Villaron E, Barbado V, Tabera S, . Optimization of mesenchymal stem cell expansion procedures by cell separation and culture conditions modification. Exp Hematol. 2008;36:1014–21.
  • Van den Dolder J, Mooren R, Vloon AP, Stoelinga PJ, Jansen JA. Platelet-rich plasma: quantification of growth factor levels and the effect on growth and differentiation of rat bone marrow cells. Tissue Eng. 2006;12:3067–73.
  • Ng F, Boucher S, Koh S, Sastry KS, Chase L, Lakshmipathy U, . PDGF, TGF-beta, and FGF signaling is important for differentiation and growth of mesenchymal stem cells (MSCs): transcriptional profiling can identify markers and signaling pathways important in differentiation of MSCs into adipogenic, chondrogenic, and osteogenic lineages. Blood. 2008;112:295–307.
  • Sotiropoulou PA, Perez SA, Salagianni M, Baxevanis CN, Papamichail M. Characterization of the optimal culture conditions for clinical scale production of human mesenchymal stem cells. Stem Cells. 2006;24:462–71.
  • Nekanti U, Mohanty L, Venugopal P, Balasubramanian S, Totey S, Ta M. Optimization and scale-up of Wharton's jelly-derived mesenchymal stem cells for clinical applications. Stem Cell Res. 2010;5:244–54.
  • Chase LG, Lakshmipathy U, Solchaga LA, Rao MS, Vemuri MC. A novel serum-free medium for the expansion of human mesenchymal stem cells. Stem Cell Res Ther. 2010:1–8.
  • Ma D, Ma Z, Zhang X, Wang W, Yang Z, Zhang M, . Effect of age and extrinsic microenvironment on the proliferation and osteogenic differentiation of rat dental pulp stem cells in vitro. J Endod. 2009;35:1546–53.
  • Bonab MM, Alimoghaddam K, Talebian F, Ghaffari SH, Ghavamzadeh A, Nikbin B. Aging of mesenchymal stem cell in vitro. BMC Cell Biol. 2006:1–14.
  • Tonti GA, Mannello F. From bone marrow to therapeutic applications: different behaviour and genetic/epigenetic stability during mesenchymal stem cell expansion in autologous and foetal bovine sera? Int J Dev Biol. 2008;52:1023–32.
  • Wang Y, Huso DL, Harrington J, Kellner J, Jeong DK, Turney J, . Outgrowth of a transformed cell population derived from normal human BM mesenchymal stem cell culture. Cytotherapy. 2005;7:509–19.
  • Capelli C, Domenghini M, Borleri G, Bellavita P, Poma R, Carobbio A, . Human platelet lysate allows expansion and clinical grade production of mesenchymal stromal cells from small samples of bone marrow aspirates or marrow filter washouts. Bone Marrow Transplant. 2007;40:785–91.
  • Duocet C, Ernou I, Zhang Y, Llense JR, Begot L, Holy X, . Platelet lysates promote mesenchymal stem cell expansion: a safety substitute for animal serum in cell-based therapy applications. J Cell Physiol. 2005;205:228–36.
  • Govindasamy V, Abdullah AN, Ronald VS, Musa S, Ab Aziz ZA, Zain BR, . Inherent differential propensity of dental pulp stem cells derived from human deciduous and permanent teeth. J Endod. 2010;36:1504–15.
  • Shibata KR, Aoyama T, Shima Y, Fukiage K, Otsuka S, Furu M, . Expression of the p16INK4A gene is associated closely with senescence of human mesenchymal stem cells and is potentially silenced by DNA methylation during in vitro expansion. Stem Cells. 2007;25:2371–82.
  • Tarte K, Gaillard J, Lataillade JJ, Fouillard L, Becker M, Mossafa H, . Clinical-grade production of human mesenchymal stromal cells: occurrence of aneuploidy without transformation. Blood. 2010;115:1549–53.
  • Janetzko K, Cazenave JP, Klüter H, Kientz D, Michel M, Beris P, . Therapeutic efficacy and safety of photochemically treated apheresis platelets processed with an optimized integrated set. Transfusion. 2005;45:1443–52.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.