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Original Article

Flupirtine dependence and withdrawal syndrome

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Pages 335-336 | Received 25 Feb 2015, Accepted 10 Mar 2015, Published online: 18 Sep 2015

References

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  • Klinger, F., et al. (2012). Concomitant facilitation of GABAA receptors and KV7 channels by the non-opioid analgesic flupirtine. British Journal of Pharmacology, 166, 1631–1642
  • Kornhuber, J., et al. (1999). Flupirtine shows functional NMDA receptor antagonism by enhancing Mg2+ block via activation of voltage independent potassium channels: Rapid communication. Journal of Neural Transmission, 106, 857–867
  • Nickel, B., Borbe, H.O., & Szelenyi, I. (1990). Investigations with the novel non-opioid analgesic flupirtine in regard to possible benzodiazepine-like abuse inducing potential. Arzneimittelforschung, 40, 905–908
  • Stoessel, C., et al. (2010). Positive reinforcing effects of flupirtine – Two case reports. Progress in Neuropsychopharmacology and Biological Psychiatry, 34, 1120–1121
  • Szelenyi, I. (2013). Flupirtine: A re-discovered drug, revisited. Inflammation Research, 62, 251–258

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