2,207
Views
4
CrossRef citations to date
0
Altmetric
Research Article

Inhibitory effects of Aphanizomenon flos-aquae constituents on human UDP-glucose dehydrogenase activity

, , , , &
Pages 1492-1497 | Received 30 Nov 2015, Accepted 22 Jan 2016, Published online: 23 Feb 2016

References

  • Egger S, Chaikuad A, Kavanagh KL, et al. Structure and mechanism of human UDP-glucose 6-dehydrogenase. J Biol Chem 2011;286:23877–87
  • Vigetti D, Karousou E, Viola M, et al. Hyaluronan: biosynthesis and signaling. Biochim Biophys Acta 2014;1840:2452–9
  • Aaltomaa S, Lipponen P, Tammi R, et al. Strong stromal hyaluronan expression is associated with PSA recurrence in local prostate cancer. Urol Int 2002;69:266–72
  • Anttila MA, Tammi RH, Tammi MI, et al. High levels of stromal hyaluronan predict poor disease outcome in epithelial ovarian cancer. Cancer Res 2000;60:150–5
  • Auvinen P, Tammi R, Parkkinen J, et al. Hyaluronan in peritumoral stroma and malignant cells associates with breast cancer spreading and predicts survival. Am J Pathol 2000;156:529–36
  • Ropponen K, Tammi M, Parkkinen J, et al. Tumor cell-associated hyaluronan as an unfavorable prognostic factor in colorectal cancer. Cancer Res 1998;58:342–7
  • Bourguignon LY, Shiina M, Li JJ. Hyaluronan-CD44 interaction promotes oncogenic signaling, microRNA functions, chemoresistance, and radiation resistance in cancer stem cells leading to tumor progression. Adv Cancer Res 2014;123:255–75
  • Singleton PA. Hyaluronan regulation of endothelial barrier function in cancer. Adv Cancer Res 2014;123:191–209
  • Simpson MA, Wilson CM, McCarthy JB. Inhibition of prostate tumor cell hyaluronan synthesis impairs subcutaneous growth and vascularization in immunocompromised mice. Am J Pathol 2002;161:849–57
  • Huh JW, Choi MM, Yang SJ, et al. Inhibition of human UDP-glucose dehydrogenase expression using siRNA expression vector in breast cancer cells. Biotechnol Lett 2005;27:1229–32
  • Egger S, Chaikuad A, Kavanagh KL, et al. UDP-glucose dehydrogenase: structure and function of a potential drug target. Biochem Soc Trans 2010;38:1378–85
  • Wang TP, Pan YR, Fu CY, Chang HY. Down-regulation of UDP-glucose dehydrogenase affects glycosaminoglycans synthesis and motility in HCT-8 colorectal carcinoma cells. Exp Cell Res 2010;316:2893–902
  • Rowland A, Miners JO, Mackenzie PI. The UDP-glucuronosyltransferases: their role in drug metabolism and detoxification. Int J Biochem Cell Biol 2013;45:1121–32
  • Li L, Hu H, Xu S, et al. Roles of UDP-glucuronosyltransferases in phytochemical metabolism of herbal medicines and the associated herb-drug interactions. Curr Drug Metab 2012;13:615–23
  • Grancharov K, Naydenova Z, Lozeva S, Golovinsky E. Natural and synthetic inhibitors of UDP-glucuronosyltransferase. Pharmacol Ther 2001;89:171–86
  • Grill AE, Koniar B, Panyam J. Co-delivery of natural metabolic inhibitors in a self-microemulsifying drug delivery system for improved oral bioavailability of curcumin. Drug Deliv Transl Res 2014;4:344–52
  • Baroni L, Scoglio S, Benedetti S, et al. Effect of a Klamath algae product (“AFA-B12”) on blood levels of vitamin B12 and homocysteine in vegan subjects: a pilot study. Int J Vitam Nutr Res 2009;79:117–23
  • Scoglio S, Benedetti S, Canino C, et al. Effect of a 2-month treatment with Klamin, a Klamath algae extract, on the general well-being, antioxidant profile and oxidative status of postmenopausal women. Gynecol Endocrinol 2009;25:235–40
  • Benedetti S, Rinalducci S, Benvenuti F, et al. Purification and characterization of phycocyanin from the blue-green alga Aphanizomenon flos-aquae. J Chromatogr B Analyt Technol Biomed Life Sci 2006;833:12–18
  • Scoglio S, Benedetti Y, Benvenuti F, et al. Selective monoamine oxidase B inhibition by an Aphanizomenon flos-aquae extract and by its constitutive active principles phycocyanin and mycosporine-like amino acids. Phytomedicine 2014;21:992–7
  • Benedetti S, Benvenuti F, Pagliarani S, et al. Antioxidant properties of a novel phycocyanin extract from the blue-green alga Aphanizomenon flos-aquae. Life Sci 2004;75:2353–62
  • Benedetti S, Benvenuti F, Scoglio S, Canestrari F. Oxygen radical absorbance capacity of phycocyanin and phycocyanobilin from the food supplement Aphanizomenon flos-aquae. J Med Food 2010;13:223–7
  • Canestrari F, Benvenuti F, Benedetti S, et al Antinflammatory properties of phycocyanin from Aphanizomenon flos-aquae. Prog Nutr 2006;8:99–103
  • Sedriep S, Xia X, Marotta F, et al Beneficial nutraceutical modulation of cerebral erythropoietin expression and oxidative stress: an experimental study. J Biol Regul Homeost Agents 2011;25:187–94
  • Rastogi RP, Sinha RP, Moh SH, et al. Ultraviolet radiation and cyanobacteria. J Photochem Photobiol B 2014;141:154–69
  • Wada N, Sakamoto T, Matsugo S. Multiple roles of photosynthetic and sunscreen pigments in cyanobacteria focusing on the oxidative stress. Metabolites 2013;3:463–83
  • Sommer BJ, Barycki JJ, Simpson MA. Characterization of human UDP-glucose dehydrogenase. CYS-276 is required for the second of two successive oxidations. J Biol Chem 2004;279:23590–6
  • Beale SI, Cornejo J. Biosynthesis of phycobilins. 3(Z)-phycoerythrobilin and 3(Z)-phycocyanobilin are intermediates in the formation of 3(E)-phycocyanobilin from biliverdin IX alpha. J Biol Chem 1991;266:22333–40
  • Hwang EY, Huh JW, Choi MM, et al. Inhibitory effects of gallic acid and quercetin on UDP-glucose dehydrogenase activity. FEBS Lett 2008;582:3793–7
  • Koníčková R, Vaňková K, Vaníková J, et al. Anti-cancer effects of blue-green alga Spirulina platensis, a natural source of bilirubin-like tetrapyrrolic compounds. Ann Hepatol 2014;13:273–83

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.