152
Views
3
CrossRef citations to date
0
Altmetric
Review Article

The triple-I (interactive, intersectorial, interdisciplinary) approach to validate “omics” investigations on body fluids and tissues in perinatal medicine

, , , &

References

  • Fanos V, Van Den Anker J, Noto A, et al. Metabolomics in neonatology: fact or fiction? Semin Fetal Neonatal Med 2013;18:3–12
  • Tabak LA. A revolution in biomedical assessment: the development of salivary diagnostics. J Dent Educ 2001;65:1335–9
  • Mussap M, Antonucci R, Noto A, Fanos V. The role of metabolomics in neonatal and pediatric laboratory medicine. Clin Chim Acta 2013;15:127–38
  • Buonocore G, Mussap M, Fanos V. Proteomics and metabolomics: can they solve some misteries of the newborn? J Matern Fetal Med 2013;26:7–8
  • Fanos V, Yurdakok M. Personalized neonatal medicine. J Matern fetal Neonatal Med 2010;23:4–6
  • Nielsen M. Reinventing discovery: the new era of networked science. Princeton, NJ: Princeton University Press; 2011
  • Fanos V. Cells, the tree, medicines and the tailor. Curr Pharm Des 2012;18:2995–6
  • Castagnola M, Inzitari R, Fanali C, et al. The surprising composition of salivary proteome of preterm human newborn. Mol Cell Proteomics 2011;10:M110.003467. doi: 10.1074/mcp.M110.003467
  • Cabras T, Pisano E, Boi R, et al. Age-dependent modifications of the human salivary protein complex. J Proteome Res 2009;8:4126–34
  • Manconi B, Cabras T, Pisano E, et al. Modifications of the acidic soluble salivary proteome in human children from birth to the age of 48 months investigated by a top-down HPLC-ESI-MS platform. J Proteomics 2013;91:536–43
  • Inzitari R, Cabras T, Onnis G, et al. Different isoforms and post–traslational modifications of human salivary acidic proline-rich proteins. Proteomics 2005;5:805–15
  • Nemolato S. Thymosin β4 and β10 levels in pre-term newborn oral cavity and foetal salivary glands evidence a switch of secretion during foetal development. Plos One 2009;4:e5109
  • Nemolato S. Different thymosin beta-4 immunoreactivity in foetal and adult gastrointestinal tract. PlosOne 2010;5:e9111
  • Faa G, Nemolato S, Cabras T, et al. Thymosin beta-4 expression reveals intriguing similarities between fetal and cancer cells. Ann N Y Acad Sci 2012;1269:53–60
  • Nemolato S, Cabras T, Restivo A, et al. Thymosin beta-4 expression in colorectal polyps and adenomas. Clinics 2013;58:1220–4
  • Castagnola M, Nemolato S, Restivo A, et al. Thymosin beta-4 in colorectal cancer is localized predominantly at the invasion front in tumor cells undergoing epithelial-mesenchymal transition. Cancer Biol Ther 2012;7:191–7
  • Fanos V, Noto A, Xanthos T, et al. Metabolomics network characterization of resuscitation after normocapnic hypoxia in a newborn piglet model supports the hypothesis that room air is better. Biomed Res Int 2014;2014:731620 . doi: 10.1155/2014/731620
  • Murgia F, Noto A, Iacovidou N, et al. Is the quickness of resuscitation after hypoxia influenced by the oxygen concentration? Metabolomics in piglets resuscitated with different oxygen concentrations. J Pediatr Neonat Individual Med 2013;2:e020233
  • Faa G, Fanos V, Fanni D, et al. Reoxygenation of asphyxiated newborn piglets: administration of 100% oxygen causes significantly higher apoptosis in cortical neurons, as compared to 21%. Biomed Res Int 2014;2014:476349. doi: 10.1155/2014/476349
  • Faa A, Xanthos T, Fanos V, et al. Hypoxia-induced endothelial damage and microthrombosis in myocardial vessels of newborn landrace/large white piglets. Biomed Res Int 2014;2014:619284. doi: 10.1155/2014/619284
  • Seidl R, Stöckler-Ipsiroglu S, Rolinski B, et al. Energy metabolism in graded perinatal asphyxia of the rat. Life Sci 2000;4:421–35

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.