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Research Article

Antioxidant properties of fullerenol C60(OH)24 in rat kidneys, testes, and lungs treated with doxorubicin

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Pages 298-305 | Received 09 Feb 2010, Accepted 12 Apr 2010, Published online: 21 May 2010

References

  • Aebi H. 1974. Catalase. In: Bergmayer HU, editor. Methods of enzymatic analysis. New York: Academic Press. pp 673–677.
  • Anderson R, Barron RA. 2005. Reaction of hydroxyfullerene with metal salts: a route to remediation and immobilization. J Am Chem Soc 127:10458–10459.
  • Andrievsky GV, Bruskov VI, Tykhomyrov AA, Gudkov SV. 2009. Peculiarities of the antioxidant and radioprotective effects of hydrated C60 fullerene nanostructures in vitro and in vivo. Free Radic Biol Med 47:786–793.
  • Azambuja E, Fleck JF, Batista RG, Menna Barreto SS. 2005. Bleomycin lung toxicity: who are the patients with increased risk. Pulm Pharmacol Ther 18:363–366.
  • Beutler E. 1984. Red cell metabolism: A manual of biochemical methods. NewYork: Grune&Stratton.
  • Bihari P, Vippola M, Schultes S, Praetner M, Khandoga AG, Reichel CA, Coester C, Tuomi T, Rehberg M, Krombach F. 2008. Optimized dispersion of nanoparticles for biological in vitro and in vivo studies. Particle Fibre Toxicol 5: 14.
  • Blum J, Fridovic I. 1985. Inactivation of glutathione-peroxidase by superoxide radical. Arch Biochem Biophys 249:500–508.
  • Bogdanovic G, Kojic V, Djordjevic A, Canadanovic-Brunet M, Vojinovic-Miloradov M, Baltic VV. 2004. Modulating activity of fullerenol C60(OH)22 on doxorubicin-induced cytotoxicity. Toxicol In Vitro 18:629–637.
  • Bogdanović V, Stankov K, Ičević I, Žikić D, Šolajić S, Djordjevic A, Bogdanovic G. 2008. Fullerenol C60(OH)24 effects on antioxidative enzymes activity in irradiated human erythroleukemia cell line. J Radiat Res 49:321–327.
  • Brant JA, Robichaund CO, Wiesner M. 2007. Fullerol cluster formation in aqueous solutions: implications for environmental release. J Colloid Interf Sci 314:281–288.
  • Cai X, Jia H, Liu Z, Hou B, Luo C, Feng Z, Li W, Liu J. 2008. Polyhydroxylated fullerene derivative C60(OH)24 prevents mitochondrial dysfunction and oxidative demage in an MMP+-induced cellular model of Parkinson’s disease. J Neurosci Res 86:3622–3634.
  • Chaudhuri P, Harfouche R, Soni S, Hentschel S, Sengupta S. 2010. Shape effect of carbon nanovectors on angiogenesis. ACS Nano 4:574–582.
  • Chaudhuri P, Paraskar A, Soni S, Mashelkar RA, Sengupta S. 2009. Fullerenol-cytotoxic conjugates for cancer chemotherapy. ACS Nano 3:2505–2514.
  • Chen YW, Hwang KC, Yen CC, Lai LL. 2004. Fullerene derivates protect against oxidative stress in RAW 264.7 cells and ischemia-reperfused lungs. Am J Physiol Regul Integr Comp Physiol 287:21–26.
  • Djordjevic A, Canadanovic-Brunet J, Vojinovic-Miloradov M, Bogdanovic G. 2005. Antioxidant properties and hypothetical radical mechanism of fullerenol C60(OH)24. Oxi Commun 27:213–218.
  • Djordjevic A, Vojinović-Miloradov M, Petranović N, Devečerski A, Lazar  D, Ribar B.1998. Catalytic preparation and characterization of C60Br24. Fullerene Sci Technol 6:689–694.
  • Djordjevic-Milic V, Stankov K, Injac R, Djordjevic A, Srdjenovic B, Govedarica B, Radic N, Simic VD, Strukelj B. 2009. Activity of antioxidative enzymes in erythrocytes after a single dose administration of doxorubicin in rats pretreated with fullerenol C60(OH)24. Toxicol Mech Meth 19:24–28.
  • Faraji AH, Wipf P. 2009. Nanoparticles in cellular drug delivery, Bioorg Med Chem 17:2950–2962.
  • Foley S, Crowley C, Smaihi M, Bonfils C, Erlanger BF, Seta P, Larroque C. 2002. Cellular localization of a water-soluble fullerene derivative. Biochem Biophys Res Commun 294:116–119.
  • Griffin Green EA, Zaleska MM, Erecsinska M. 1988. Adriamycin induced lipid peroxidation in mitochondria and microsomes. Biochem Pharmacol 37:3071–3077.
  • Injac R, Boskovic M, Perse M, Koprivec-Furlan E, Cerar A, Djordjevic A, Strukelj B. 2008c. Acute doxorubicin nephrotoxicity in rats with malignant neoplasm can be successfully treated with fullerenol C60(OH)24 via suppresison of oxidative stress. Pharmacol Rep 60:742–749.
  • Injac R, Perse M, Boskovic M, Djordjevic-Milic V, Djordjevic A, Hvala A, Cerar A, Strukelj B. 2008a.. Cardioprotective effects of fullerenol C60(OH)24 on a single dose doxorubicin-induced cardiotoxicity in rats with malignant neoplasm. Technol Cancer Res Treat 7:15–25.
  • Injac R, Perse M, Obermajer N, Djordjevic-Milic V, Prijatelj M, Djordjevic A, Cerar A, Strukelj B. 2009b. Protective effects of fullerenol C60(OH)24 against doxorubicin-induced cardiotoxicity and hepatotoxicity in rats with colorectal cancer. Biomaterials 30:1184–1196.
  • Injac R, Perse M, Obermajer N, Djordjevic-Milic V, Prijatelj M, Djordjevic A, Cerar A, Strukelj B. 2008b. Potential hepatoprotective effects of fullerenol C60(OH)24 in doxorubicin-induced hepatotoxicity in rats with mammary carcinomas. Biomaterials 29:3451–3460.
  • Injac R, Radic N, Govedarica B, Perse M, Cerar A, Djordjevic A, Strukelj B. 2009a. Acute doxorubicin pulmotoxicity in rats with malignant neoplasm is effectively treated with fullerenol C60(OH)24 trough inhibition of oxidative stress. Pharmacol Rep 61:335–342.
  • Janssen YMW, Borm PJA, Van Houten B, Mossman BT. 1993. Cell and tissue responses to oxidative demage. Lab Invest 69:261–274.
  • Kalaiselvi P, Prgasam V, Chinnikishnan S, Veena CK, Sundarapandiyan R, Varalakshmi P. 2005. Counteracting adriamycin-induced oxidative stress by administration of N-acetyl cysteine and vitamin E. Clin Chem Lab Med 43:834–840.
  • Manoury B, Nenan S, Leclerc O, Guenon I, Lagente V, Boichot E, Bertrand CP, Lagente V. 2005. The absence of reactive oxygen species production protects mice against bleomycin-induced pulmonary fibrosis. Respir Res 6:11.
  • McCord JM, Fridovich I. 1969. Superoxide dismutase, an enzymic function for erythrocuprein (hemocuprein). J Biol Chem 244:6049–6055.
  • Meadors M, Floyd J, Perry MC. 2006. Pulmonary toxicity of chemotherapy. Semin Oncol 33:98–105.
  • Milic-Torres V, Srdjenovic B, Jacevic V, Dragojevic Simic V, Djordjevic A, Simplício AL. 2010. Fullerenol C60(OH)24 successfully prevents doxorubicin induced acute cardiotoxicity in rats. Pharmacol Rep 62: in press.
  • Mimnaugh EG, Trush MA, Gram TE. 1986. A possible role of membrane lipid peroxidation in anthracycline nephrotoxicity. Biochem Pharmacol 35:4327–4335.
  • Minotti G. 1993. Sources and role of iron in lipid peroxidation. Chem Res Toxicol 6:134–146.
  • Mirkov S, Djordjevic A, Andric N, Andric S, Kostic T, Bogdanovic G, Vojinovic-Miloradov M, Kovacevic R. 2004. Nitric-oxide scavenging activity of polyhydroxylated fullerenol C60(OH)24. Nitric Oxide Biol Chem 11:201–207.
  • Miyamoto Y, Koh YH, Park YS, Fujiwara N, Sakiyama H, Misonou Y, Ookawara T, Suzuki K, Honke K, Taniguchi N. 2003. Oxidative stress caused by inactivation of gluthathione peroxidase and adaptive responses. Biol Chem 384:567–574.
  • Mrdjanovic J, Solajic S, Bogdanovic V, Stankov K, Bogdanovic G, Djordjevic A. 2009. Effects of fullerenol C60(OH)24 on the frequency of micronuclei and chromosome aberrations in CHO-K1 cells. Mutat Res Genet Toxicol Environ Mutagen 680:25–30.
  • Murugan MA, Gangadharan B, Mathur PP. 2002. Antioxidative effect of fullerenol on goat epididymal spermatozoa. Asian J Androl 4:149–152.
  • Öz E, Ilham MN. 2006. Effects of melatonin in reducing the toxic effects of doxorubicin. Mol Cell Biochem 286:11–15.
  • Prahalathan C, Selvacumar E, Varalakshami P. 2005. Protective effect of lipoic acid on adriamycine-induced testicular toxicity. Clin Chim Acta 360:160–166.
  • Sadik NAH, Ismail MF, Shaheen AA. 2008. Effect of probucol and deferoxamine against adriamycin toxicity in cardiac and renal tissues of rats. Indian J Biochem Biophys 45:44–50.
  • Trajković S, Dobrić S, Jačević V, Dragojević-Simić V, Milovanović Z, Đorđevic A. 2007. Tissue protective effects of fullerenol C60(OH)24 and amifostine in irradiated rats. Colloids Surf B Biointerfaces 58:39–43.
  • Uchiama M, Mihara M. 1978. Determination of malonaldehide precursor in tissues by thiobarbituric acid test. Anal Biochem 8:271–278.
  • Vileno B, Marcox PR, Lekka M, Sienkiewicz A, Fehre T, Forro L. 2006. Spectroscopic and physical properties of a highly derivatiyed C60 fullerol. Adv Funct Mater 16:120–128.
  • Wilson SR, Schuster DI, Nuber B, Meier MS, Maggini M, Prato M, Taylor R. 2000. Organic chemistry of fullerenes. In: Kadish KM, Ruoff RS, editors. Fullerenes: Chemistry, physics and technology. New York: Wiley-Interscience. pp 91–177.
  • Xia T, Kovochich M, Brant J, Hotze M, Sempf J, Oberley T, Sioutas C, Yeh JI, Wiesner MR, Nel AE. 2006. Comparison of the abilities of ambient and manufactured nanoparticle to induce cellular toxicity according to an oxidative stress paradigm. Nano Lett 6:1794–1807.
  • Yagmurca M, Erdogan H, Iraz M, Songur A, Ucar M, Fadilloglu E. 2004. Caffeic acid phenethyl ester as a protective agent against doxorubicin nephrotoxicity in rats. Clin Chim Acta 348:27–34.
  • Yamavaki H, Iwai N. 2006. Cytotoxicity of water soluble fullerenol in vascular endothelial cells. Am J Physiol Cell Physiol 290:1495–1502.
  • Yeh YC, Lai HC, Ting CT, Lee WL, Wang LC, Lai HC, Liu TJ. 2007. Protection by doxycycline against doxorubicin-induced oxidative stress and apoptosis in mouse testes. Biochem Pharmacol 74:969–980.
  • Yin JJ, Lao F, Fu PP, Kanakamma PP, Shen CKF, Luh TY. 2009. The scavenging of reactive oxygen species and the potential for cell protection by functionalized fullerene materials. Biomaterials 30:611–621.

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