Investigating the effect of lead acetate on rat bone marrow-derived mesenchymal stem cells toxicity: Role of apoptosis

References

• Ashkenazi A, Dixit VM. 1998. Death receptors: signaling and modulation. Science 281:1305–1308.
   PubMed Web of Science ®Google Scholar
• Aubin JE, Liu F, Malaval L, Gupta AK. 1995. Osteoblast and chondroblast differentiation. Bone 17:77S–83S
   PubMed Web of Science ®Google Scholar
• Boise LH, Gonzalez-Garcia M, Postema CE, Ding L, Lindsten T, Turka LA, Mao X, Nunez G, Thompson CB. 1993. bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death. Cell 74:597–608.
   PubMed Web of Science ®Google Scholar
• Boyd JM, Gallo GJ, Elangovan B, Houghton AB, Malstrom S, Avery BJ, Ebb RG, Subramanian T, Chittenden T, Lutz RJ, Chinnadurai G. 1995. Bik, a novel death-inducing protein shares a distinct sequence motif with Bcl-2 family proteins and interacts with viral and cellular survival-promoting proteins. Oncogene 11:1921–1928.
   PubMed Web of Science ®Google Scholar
• Bradford MM. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248–254.
   PubMed Web of Science ®Google Scholar
• Carmouche JJ, Puzas JE, Zhang X, Tiyapatanaputi P, Cory-Slechta DA, Gelein R, Zuscik M, Rosier RN, Boyce BF, O’Keefe RJ, Schwarz EM. 2005. Lead exposure inhibits fracture healing and is associated with increased chondrogenesis, delay in cartilage mineralization, and a decrease in osteoprogenitor frequency. Environ Health Perspect 113:749–755.
   PubMed Web of Science ®Google Scholar
• Chittenden T, Harrington EA, O’Connor R, Flemington C, Lutz RJ, Evan GI, Guild BC. 1995. Induction of apoptosis by the Bcl-2 homologue Bak. Nature 374:733–736.
   PubMed Web of Science ®Google Scholar
• Creagh EM, Martin SJ. 2001. Caspases: cellular demolition experts. Biochem Soc Trans 29:696–702.
   PubMed Web of Science ®Google Scholar
• Escribano A, Revilla M, Hernandez ER, Seco C, Gonzalez-Riola J, Villa LF, Rico H. 1997. Effect of lead on bone development and bone mass: a morphometric, densitometric, and histomorphometric study in growing rats. Calcif Tissue Int 60:200–203.
   PubMed Web of Science ®Google Scholar
• Fox DA, He L, Poblenz AT, Medrano CJ, Blocker YS, Srivastava D. 1998. Lead-induced alterations in retinal cGMP phosphodiesterase trigger calcium overload, mitochondrial dysfunction and rod photoreceptor apoptosis. Toxicol Lett 102–103:359–361.
   Web of Science ®Google Scholar
• Friedenstein AJ, Gorskaja JF, Kulagina NN. 1976. Fibroblast precursors in normal and irradiated mouse hematopoietic organs. Exp Hematol 4:267–274.
   PubMed Web of Science ®Google Scholar
• Gross A, McDonnell JM, Korsmeyer SJ. 1999. BCL-2 family members and the mitochondria in apoptosis. Genes Dev 13:1899–1911.
   PubMed Web of Science ®Google Scholar
• Gruber HE, Gonick HC, Khalil-Manesh F, Sanchez TV, Motsinger S, Meyer M, Sharp CF. 1997. Osteopenia induced by long-term, low- and high-level exposure of the adult rat to lead. Miner Electrolyte Metab 23:65–73.
   PubMedGoogle Scholar
• Hockenbery D, Nunez G, Milliman C, Schreiber RD, Korsmeyer SJ. 1990. Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 348:334–336.
   PubMed Web of Science ®Google Scholar
• Holz JD, Sheu TJ, Drissi H, Matsuzawa M, Zuscik MJ, Puzas JE. 2007. Environmental agents affect skeletal growth and development. Birth Defects Res C Embryo Today 81:41–50.
   PubMedGoogle Scholar
• Iavicoli I, Carelli G, Sgambato A, Masci O, Ardito R, Cittadini A, Castellino N. 2001. Lead inhibits growth and induces apoptosis in normal rat fibroblasts. Altern Lab Anim 29:461–469.
   PubMed Web of Science ®Google Scholar
• Jiang X, Wang X. 2004. Cytochrome C-mediated apoptosis. Annu Rev Biochem 73:87–106.
   PubMed Web of Science ®Google Scholar
• Kozopas KM, Yang T, Buchan HL, Zhou P, Craig RW. 1993. MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2. Proc Natl Acad Sci USA 90:3516–3520.
   PubMed Web of Science ®Google Scholar
• Krane SM, Holick MF. 1998. Metabolic bone disease in Harrison’s principles of internal medicine. In: Fauci AS, editor. 14th ed. New York: McGraw-Hill, Inc. pp 2247–2253.
   Google Scholar
• Laemmli UK. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680–685.
   PubMed Web of Science ®Google Scholar
• Lidsky TI, Schneider JS. 2003. Lead neurotoxicity in children: basic mechanisms and clinical correlates. Brain 126:5–19.
   PubMed Web of Science ®Google Scholar
• Mosmann T. 1983. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65:55–63.
   PubMed Web of Science ®Google Scholar
• Needleman H, 2004. Lead poisoning. Ann Rev Med 55:209–222.
   PubMed Web of Science ®Google Scholar
• Oberto A, Marks N, Evans HL, Guidotti A. 1996. Lead (Pb+2) promotes apoptosis in newborn rat cerebellar neurons: pathological implications. J Pharmacol Exp Ther 279:435–442.
   PubMed Web of Science ®Google Scholar
• Oltvai ZN, Milliman CL, Korsmeyer SJ. 1993. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74:609–619.
   PubMed Web of Science ®Google Scholar
• Pulido MD, Parrish AR. 2003. Metal-induced apoptosis: mechanisms. Mutat Res 533:227–241.
   PubMed Web of Science ®Google Scholar
• Ronis MJ, Aronson J, Gao GG, Hogue W, Skinner RA, Badger TM, et al. 2001. Skeletal effects of developmental lead exposure in rats. Toxicol Sci 62:321–329.
   PubMed Web of Science ®Google Scholar
• Shabani A, Rabbani A. 2000. Lead nitrate induced apoptosis in alveolar macrophages from rat lung. Toxicology 149:109–114.
   PubMed Web of Science ®Google Scholar
• Sharifi AM, Baniasadi S, Jorjani M, Rahimi F, Bakhshayesh M. 2002. Investigation of acute lead poisoning on apoptosis in rat hippocampus in vivo. Neurosci Lett 329:45–48.
   PubMed Web of Science ®Google Scholar
• Sharifi AM, Mousavi SH. 2008. Studying the effects of lead on DNA fragmentation and proapoptotic bax and antiapoptotic bcl-2 protein expression in PC12 cells. Toxicol Mech Methods 18:75–79.
   PubMed Web of Science ®Google Scholar
• Sharifi AM, Mousavi SH, Bakhshayesh M, Tehrani FK, Mahmoudian M, Oryan S. 2005. Study of correlation between lead-induced cytotoxicity and nitric oxide production in PC12 cells. Toxicol Lett 160:43–48.
   PubMed Web of Science ®Google Scholar
• Sharifi AM, Mousavi SH, Jorjani M. 2010. Effect of chronic lead exposure on pro-apoptotic Bax and anti-apoptotic Bcl-2 protein expression in rat hippocampus in vivo. Cell Mol Neurobiol 30:769–774.
   PubMed Web of Science ®Google Scholar
• Silbergeld EK. 1992. Mechanisms of lead neurotoxicity, or looking beyond the lamppost. FASEB J 6:3201–3206.
   PubMed Web of Science ®Google Scholar
• Tsujimoto Y, Shimizu S. 2000. Bcl-2 family: life-or-death switch. FEBS Lett 466:6–10.
   PubMed Web of Science ®Google Scholar
• Wang ZB, Liu YQ, Cui YF. 2005. Pathways to caspase activation. Cell Biol Int 29:489–496.
   PubMed Web of Science ®Google Scholar
• Yang E, Zha J, Jockel J, Boise LH, Thompson CB, Korsmeyer SJ. 1995. Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death. Cell 80:285–291.
   PubMed Web of Science ®Google Scholar
• Zhang XD, Franco A, Myers K, Gray C, Nguyen T, Hersey P. 1999. Relation of TNF–related apoptosis-inducing ligand (TRAIL) receptor and FLICE–inhibitory protein expression to TRAIL-induced apoptosis of melanoma. Cancer Res 59:2747–2753.
   PubMed Web of Science ®Google Scholar
• Zuscik MJ, Ma L, Buckley T, Puzas JE, Drissi H, Schwarz EM, O’Keefe RJ. 2007. Lead induces chondrogenesis and alters transforming growth factor–beta and bone morphogenetic protein signaling in mesenchymal cell populations. Environ Health Perspect 115:1276–1282.
   PubMed Web of Science ®Google Scholar