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Research Article

EGCG inhibits Cd2+-induced apoptosis through scavenging ROS rather than chelating Cd2+ in HL-7702 cells

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Pages 259-267 | Received 19 Nov 2013, Accepted 29 Dec 2013, Published online: 22 Jan 2014

References

  • Abib RT, Peres KC, Barbosa AM, et al. (2011). Epigallocatechin-3-gallate protects rat brain mitochondria against cadmium-induced damage. Food Chem Toxicol 49:2618–23
  • Adiele RC, Stevens D, Kamunde C. (2012). Differential inhibition of electron transport chain enzyme complexes by cadmium and calcium in isolated rainbow trout (Oncorhynchus mykiss) hepatic mitochondria. Toxicol Sci 127:110–19
  • Andersen O. (1999). Principles and recent developments in chelation treatment of metal intoxication. Chem Rev 30:2683–710
  • Anuradha CD, Kanno S, Hirano S. (2001). Oxidative damage to mitochondria is a preliminary step to caspase-3 activation in fluoride-induced apoptosis in HL-60 cells. Free Radic Biol Med 31:367–73
  • Apak R, Guclu K, Ozyurek M, Karademir SE. (2004). Novel total antioxidant capacity index for dietary polyphenols and vitamins C and E, using their cupric ion reducing capability in the presence of neocuproine: CUPRAC method. J Agric Food Chem 52:7970–81
  • Aronis A, Melendez JA, Golan O, et al. (2003). Potentiation of Fas-mediated apoptosis by attenuated production of mitochondria-derived reactive oxygen species. Cell Death Differ 10:335–44
  • Ayala P, Montenegro J, Vivar R, et al. (2012). Attenuation of endoplasmic reticulum stress using the chemical chaperone 4-phenylbutyric acid prevents cardiac fibrosis induced by isoproterenol. Exp Mol Pathol 92:97–104
  • Buttke TM, Sandstrom PA. (1994). Oxidative stress as a mediator of apoptosis. Immunol Today 15:7–10
  • Cao XJ, Chen R, Li AP, Zhou JW. (2007). JWA gene is involved in cadmium-induced growth inhibition and apoptosis in HEK-293T cells. J Toxicol Environ Health A 70:931–7
  • Chandra J, Samali A, Orrenius S. (2000). Triggering and modulation of apoptosis by oxidative stress. Free Radic Biol Med 29:323–33
  • Chen Q, Wang Y, Xu K, et al. (2010). Curcumin induces apoptosis in human lung adenocarcinoma A549 cells through a reactive oxygen species-dependent mitochondrial signaling pathway. Oncol Rep 23:397–403
  • Chen X, Wang J, Qin Q, et al. (2012). Mono-2-ethylhexyl phthalate induced loss of mitochondrial membrane potential and activation of Caspase3 in HepG2 cells. Environ Toxicol Pharmacol 33:421–30
  • Daxhelet GA, Coene MM, Hoet PP, Cocito CG. (1989). Spectrofluorometry of dyes with DNAs of different base composition and conformation. Anal Biochem 179:401–3
  • Eşrefoğlu M, Gül M, Doğru MI, et al. (2007). Adrenomedullin fails to reduce cadmium-induced oxidative damage in rat liver. Exp Toxicol Pathol 58:367–74
  • Fernandez MT, Mira ML, Florencio MH, Jennings KR. (2002). Iron and copper chelation by flavonoids: an electrospray mass spectrometry study. J Inorg Biochem 92:105–11
  • Gago-Dominguez M, Castelao JE, Pike MC, et al. (2005). Role of lipid peroxidation in the epidemiology and prevention of breast cancer. Cancer Epidemiol Biomarkers Prev 14:2829–39
  • Ge R, Ma WH, Li YL, Li QS. (2013). Apoptosis induced neurotoxicity of Di-n-butyl-di-(4-chlorobenzohydroxamato) Tin (IV) via mitochondria-mediated pathway in PC12 cells. Toxicol In Vitro 27:92–102
  • Giardino I, Fard AK, Hatchell DL, Brownlee M. (1998). Aminoguanidine inhibits reactive oxygen species formation, lipid peroxidation, and oxidant-induced apoptosis. Diabetes 47:1114–20
  • Guo Q, Zhao B, Li M, et al. (1996). Studies on protective mechanisms of four components of green tea polyphenols against lipid peroxidation in synaptosomes. Biochim Biophys Acta 1304:210–22
  • Habeebu SSM, Liu J, Klaassen CD. (1998). Cadmium-induced apoptosis in mouse liver. Toxicol Appl Pharmacol 149:203–9
  • Haouem S, Hmada N, Najjarb MF, et al. (2007). Accumulation of cadmium and its effects on liver and kidney functions in rats given diet containing cadmium-polluted radish bulb. Exp Toxicol Pathol 59:77–80
  • Harstad EB, Klaassen CD. (2002). Gadolinium chloride pretreatment prevents cadmium chloride-induced liver damage in both wild-type and MT-null mice. Toxicol Appl Pharmacol 180:178–85
  • Huang DJ, Zhang YM, Qi YM, et al. (2008). Global DNA hypomethylation, rather than reactive oxygen species (ROS), a potential facilitator of cadmium-stimulated K562 cell proliferation. Toxicol Lett 179:43–7
  • Inoue MB, Inoue M, Fernando Q, et al. (2002). Potentiometric and (1)H NMR studies of complexation of Al(3+) with (-)-epigallocatechin gallate, a major active constituent of green tea. J Inorg Biochem 88:7–13
  • Isbrucker RA, Bausch J, Edwards JA, Wolz E. (2006). Safety studies on epigallocatechin gallate (EGCG) preparations. Part 1: genotoxicity. Food Chem Toxicol 44:626–35
  • Jihen EH, Imed M, Fatima H, Abdelhamid K. (2008). Protective effects of selenium (Se) and zinc (Zn) on cadmium (Cd) toxicity in the liver and kidney of the rat: histology and Cd accumulation. Food Chem Toxicol 46:3522–7
  • Jung JY, Mo HC, Yang KH, et al. (2007). Inhibition by epigallocatechin gallate of CoCl2-induced apoptosis in rat PC12 cells. Life Sci 80:1355–63
  • Kobroob A, Chattipakorn N, Wongmekiat O. (2012). Caffeic acid phenethyl ester ameliorates cadmium-induced kidney mitochondrial injury. Chem Biol Interact 200:21–7
  • Lakhani SA, Masud A, Kuida K, et al. (2006). Caspases 3 and 7: key mediators of mitochondrial events of apoptosis. Science 311:847–51
  • Lambert JD, Elias RJ. (2010). The antioxidant and pro-oxidant activities of green tea polyphenols: a role in cancer prevention. Arch Biochem Biophys 501:65–72
  • Liu T, He WT, Yan C, et al. (2011). Roles of reactive oxygen species and mitochondria in cadmium-induced injury of liver cells. Toxicol Ind Health 27:249–56
  • Liu Y, Zhang S, Cai Y. (2007). Cytoprotective effects of selenium on cadmium-induced LLC-PK1 cells apoptosis by activating JNK pathway. Toxicol in Vitro 27:677–84
  • Lv X, Yu X, Wang Y, et al. (2012). Berberine inhibits doxorubicin-triggered cardiomyocyte apoptosis via attenuating mitochondrial dysfunction and increasing Bcl-2 expression. PLoS One 7:e47351
  • Ly JD, Grubb DR, Lawen A. (2003). The mitochondrial membrane potential (Δψm) in apoptosis; an update. Apoptosis 8:115–28
  • Myhre O, Andersen JM, Aarnes H, Fonnum F. (2003). Evaluation of the probes 2′,7′-dichlorofluorescin diacetate, luminol, and lucigenin as indicators of reactive species formation. Biochem Pharmacol 65:1575–82
  • Nakazato T, Ito K, Miyakawa Y, et al. (2005). Catechin, a green tea component, rapidly induces apoptosis of myeloid leukemic cells via modulation of reactive oxygen species production in vitro and inhibits tumor growth in vivo. Haematologica 90:317–25
  • Navarro RE, Santacruz H, Inoue M. (2005). Complexation of epigallocatechin gallate (a green tea extract, egcg) with Mn2+: nuclear spin relaxation by the paramagnetic ion. J Inorg Biochem 99:584–8
  • Nishikawa T, Nakajima T, Moriguchi M, et al. (2006). A green tea polyphenol, epigalocatechin-3-gallate, induces apoptosis of human hepatocellular carcinoma, possibly through inhibition of Bcl-2 family proteins. J Hepatol 44:1074–82
  • Niu X, Yang Y, Jin M, et al. (2011). Effects of motion, attenuation, and scatter corrections on gated cardiac SPECT reconstruction. Med Phys 38:6571–84
  • Ognjanović BI, Marković SD, Dordević NZ, et al. (2010). Cadmium-induced lipid peroxidation and changes in antioxidant defense system in the rat testes: protective role of coenzyme Q10 and Vitamin E. Reprod Toxicol 29:191–7
  • Oh SH, Lim SC. (2006). A rapid and transient ROS generation by cadmium triggers apoptosis via caspase-dependent pathway in HepG2 cells and this is inhibited through N-acetylcysteine-mediated catalase upregulation. Toxicol Appl Pharmacol 212:212–23
  • Ohyoshi E, Sakata T, Kurihara M. (1999). Complexation of aluminium with (−)-epigallocathechin gallate studied by spectrophotometry. J Inorg Biochem 73:31–4
  • Okuda T, Mori K, Shiota M, Ida K. (1982). Effect of the interaction of tannins with coexisting substances. II. Reduction of heavy metal ions and solubilization of precipitates. Yakugaku Zasshi 102:735–42
  • Pari L, Shagirtha K. (2012). Hesperetin protects against oxidative stress related hepatic dysfunction by cadmium in rats. Exp Toxicol Pathol 64:513–20
  • Pelicano H, Feng L, Zhou Y, et al. (2003). Inhibition of mitochondrial respiration: a novel strategy to enhance drug-induced apoptosis in human leukemia cells by a reactive oxygen species-mediated mechanism. J Biol Chem 278:37832–9
  • Prabu SM, Shagirtha K, Renugadevi J. (2011). Naringenin in combination with vitamins C and E potentially protects oxidative stress-mediated hepatic injury in cadmium-intoxicated rats. J Nutr Sci Vitaminol (Tokyo) 57:177–85
  • Raza H, John A. (2007). In vitro protection of reactive oxygen species-induced degradation of lipids, proteins and 2-deoxyribose by tea catechins. Food Chem Toxicol 45:1814–20
  • Rogalska J, Pilat-Marcinkiewicz B, Brzóska MM. (2011). Protective effect of zinc against cadmium hepatotoxicity depends on this bioelement intake and level of cadmium exposure: a study in a rat model. Chem Biol Interact 193:191–203
  • Satarug S, Moore MR. (2004). Adverse health effects of chronic exposure to low-level cadmium in foodstuffs and cigarette smoke. Environ Health Perspect 112:1099–103
  • Shih CM, Ko WC, Wu JS, et al. (2004). Mediating of caspase-independent apoptosis by cadmium through the mitochondria-ROS pathway in MRC-5 fibroblasts. J Cell Biochem 91:384–97
  • Shukla R, Kumar M. (2009). Role of Panax ginseng as an antioxidant after cadmium-induced hepatic injuries. Food Chem Toxicol 47:769–73
  • Song XY, Hu JF, Sun MN, et al. (2013). IMM-H004, a novel coumarin derivative compound, protects against amyloid beta-induced neurotoxicity through a mitochondrial-dependent pathway. Neuroscience 242:28–38
  • Stohs SJ, Bagchi D. (1995). Oxidative mechanisms in the toxicity of metal ions. Free Radic Biol Med 18:321–36
  • Tandon SK, Singh S, Prasad S, et al. (2003). Reversal of cadmium induced oxidative stress by chelating agent, antioxidant or their combination in rat. Toxicol Lett 145:211–17
  • Tzirogiannis K, Panoutsopoulos G, Demonakou M, et al. (2003). Time-course of cadmium-induced acute hepatotoxicity in the rat liver: the role of apoptosis. Arch Toxicol 77:694–701
  • Wu F, Sun H, Kluz T, et al. (2012). Epigallocatechin-3-gallate (EGCG) protects against chromate-induced toxicity in vitro. Toxicol Appl Pharmacol 258:166–75
  • Yao K, Ye P, Zhang L, et al. (2008). Epigallocatechin gallate protects against oxidative stress-induced mitochondria-dependent apoptosis in human lens epithelial cells. Mol Vis 14:217–23
  • Yu HN, Shen SR, Yin JJ. (2007). Effects of interactions of EGCG and Cd2+ on the growth of PC-3 cells and their mechanisms. Food Chem Toxicol 45:244–9
  • Zafeer MF, Waseem M, Chaudhary S, Parvez S. (2012). Cadmium-induced hepatotoxicity and its abrogation by thymoquinone. J Biochem Mol Toxicol 26:199–205
  • Zhang Y, Luo M, Zu Y, et al. (2012). Dryofragin, a phloroglucinol derivative, induces apoptosis in human breast cancer MCF-7 cells through ROS-mediated mitochondrial pathway. Chem Biol Interact 199:129–36
  • Zhou YJ, Zhang SP, Liu CW, Cai YQ. (2009). The protection of selenium on ROS mediated-apoptosis by mitochondria dysfunction in cadmium-induced LLC-PK1 cells. Toxicol In Vitro 23:288–94

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