108
Views
2
CrossRef citations to date
0
Altmetric
Research Article

Grape juice concentrate (G8000™) modulates apoptosis but not oxidative stress following rat colon carcinogenesis induced by azoxymethane

, , , , , , , & show all
Pages 91-97 | Received 19 Sep 2014, Accepted 16 Nov 2014, Published online: 22 Jan 2015

References

  • Adams JM, Cory S. (1998). The Bcl-2 protein family: arbiters of cell survival. Science 281:1322–6
  • Aguiar O Jr, Gollücke AP, de Moraes BB, et al. (2011). Grape juice concentrate prevents oxidative DNA damage in peripheral blood cells of rats subjected to a high-cholesterol diet. Br J Nutr 105:694–702
  • Anti M, Armuzzi A, Morini S, et al. (2001). Severe imbalance of cell proliferation and apoptosis in the left colon and in the rectosigmoid tract in subjects with a history of large adenomas. Gut 48:238–46
  • Barrezueta LF, Oshima CT, Lima FO, et al. (2010). The intrinsic apoptotic signaling pathway in gastric adenocarcinomas of Brazilian patients: immunoexpression of the Bcl-2 family (Bcl-2, Bcl-x, Bak, Bax, Bad) determined by tissue microarray analysis. Mol Med Rep 3:261–7
  • Baur JA, Sinclair DA. (2006). Therapeutic potential of resveratrol: the in vivo evidence. Nat Rev Drug Discov 5:493–506
  • Bianchi MLP, Antunes LMG. (1999). Radicais livres e os principais antioxidantes da dieta. Rev Nutr 12:123–30
  • Bird RP. (1995). Role of aberrant crypt foci in understanding the pathogenesis of colon cancer. Cancer Lett 93:55–71
  • Bird RP, Good CK. (2000). The significance of aberrant crypt foci in understanding the pathogenesis of colon ancer. Toxicol Lett 112–113:395–402
  • Bitsch R, Netzel M, Frank T, et al. (2004). Bioavailability and biokinetics of anthocyanins from red grape juice and red wine. J Biomed Biotechnol 2004:293–8
  • Bralley EE, Hargrove JL, Greenspan P, Hartle DK. (2007). Topical anti-inflammatory activities of vitis rotundifolia (Muscadine Grape) extracts in the tetradecanoylphorbol acetate model of ear inflammation. J Med Food 10:636–42
  • Cabrita MJ, Ricardo-da-Silva J, Laureano O. (2003). Os compostos polifenólicos das uvas e dos vinhos. México: I Seminário Internacional de Vitinicultura
  • Cancer Statistics. (2014). Available from: http://www.wcrf.org/cancer_statistics/data_specific_cancers/colorectal_cancer_statistics.php [last accessed 29 Aug 2014]
  • Chacona MR, Ceperuelo-Mallafrea V, Maymo-Masipa E, et al. (2009). Grape-seed procyanidins modulate inflammation on human differentiated adipocytes in vitro. Cytokine 47:137–42
  • Coultas L, Strasser A. (2003). The role of the Bcl-2 protein family in cancer. Semin Cancer Biol 13:115–23
  • De Beer D, Joubert E, Gelderblom WC, Manley M. (2003). Antioxidant activity of South African red and white cultivar wines: free radical scavenging. J Agric Food Chem 51:902–9
  • Debatin KM. (2004). Apoptosis pathways in cancer and cancer therapy. Cancer Immunol Immunother 53:153–9
  • Denault JB, Salvesen GS. (2002). Caspases: keys in the ignition of cell death. Chem Rev 102:4489–500
  • Duarte-Almeida JM, Santos RJ, Genovese MI, Lajolo FM. (2007). Evaluation of the antioxidant activity using the b-carotene/linoleic acid system and the DPPH scavenging method. Ciênc Tecnol Aliment Campinas ANO 26:446–52
  • Hain R, Bieseler B, Kindl H, et al. (1990). Expression of a stilbene synthase gene in Nicotiana tabacum results in synthesis of the phytoalexin resveratrol. Plant Mol Biol 15:325–35
  • Harris GK, Gupta A, Nines RG, et al. (2001). Effects of lyophilized black raspberries on azoxymethane-induced colon cancer and 8-hydroxy-2′-deoxyguanosine levels in the Fischer 344 rat. Nutr Cancer 40:125–33
  • Hasler CM, Bloch AS, Thomson CA, et al. (2004). Position of the American Dietetic Association: functional foods. J Am Diet Assoc 104:814–26
  • Instituto nacional de câncer (INCA). (2014). Coordenação de prevenção e vigilância de câncer. Estimativas 2014: incidência de câncer no Brasil. Rio de Janeiro: INCA; Avaliable from: http://www2.inca.gov.br/wps/wcm/connect/tiposdecancer/site/home/colorretal [last accessed 27 Nov 2014]
  • Jacobson MD, Weil M, Raff MC. (1997). Programmed cell death in animal development. Cell 88:347–54
  • Kasai H, Nishimura S. (1984). Hydroxylation of deoxyguanosine at the C-8 position by ascorbic acid and other reducing agents. Nucleic Acids Res 12:2137–45
  • Kauntz H, Bousserouel S, Gosse F, et al. (2012). Silibinin, a natural flavonoid, modulates the early expression of chemoprevention biomarkers in a preclinical model of colon carcinogenesis. Int J Oncol 41:849–54
  • Komarova NL, Wang L. (2004). Initiation of colorectal cancer: where do the two hits hit? Cell Cycle 3:1558–65
  • Kondo S, Toyokuni S, Iwasa Y, et al. (1999). Persistent oxidative stress in human colorectal carcinoma, but not in adenoma. Free Radic Biol Med 27:401–10
  • Lazzè MC, Pizzala R, Gutiérrez Pecharromán FJ, et al. (2009). Grape waste extract obtained by supercritical fluid extraction contains bioactive antioxidant molecules and induces antiproliferative effects in human colon adenocarcinoma cells. J Med Food 12:561–8
  • Leedham SJ, Schier S, Thliveris AT, et al. (2005). From gene mutations to tumours-stem cells in gastrointestinal carcinogenesis. Cell Prolif 38:387–405
  • Levy M, Visokai V, Lipska L, Topolcan O. (2008). Tumor markers in staging and prognosis of colorectal carcinoma. Neoplasma 55:138–42
  • Macheda ML, Stacker SA. (2008). Importance of Wnt signaling in the tumor stroma microenvironment. Curr Cancer Drug Targets 8:454–65
  • Macheix JJ, Fleuriet A, Billot J, eds. (1990). The main phenolics of fruit phenolics. In Fruit phenolics. Boca Raton (FL): CRC Press, 1–98
  • Mayer B, Oberbauer R. (2003). Mitochondrial regulation of apoptosis. News Physiol Sci 18:89–94
  • Nicholson DW. (2000). From bench to clinic with apoptosis-based therapeutic agents. Nature 407:810–16
  • Okada H, Mak TW. (2004). Pathways of apoptotic and nonapoptotic death in tumour cells. Nat Rev Cancer 4:592–603
  • Padidar S, Farquharson AJ, Williams LM, et al. (2012). High-fat diet alters gene expression in the liver and colon: links to increased development of aberrant crypt foci. Dig Dis Sci 5:1866–74
  • Preston SL, Wong WM, Chan AO, et al. (2003). Bottom-up histogenesis of colorectal adenomas: origin in the monocryptal adenoma and initial expansion by crypt fission. Cancer Res 63:3819–25
  • Tessitore L, Davit A, Sarotto I, Caderni G. (2000). Resveratrol depresses the growth of colorectal aberrant crypt foci by affecting bax and p21(CIP) expression. Carcinogenesis 21:1619–22
  • Valavanidis A, Vlachogianni T, Fiotakis K. (2009). Tobacco smoke: involvement of reactive oxygen species and free radicals in mechanisms of oxidative damage, carcinogenesis and synergistic effects with other respirable particles. Int J Environ Res Public Health 6:445–62
  • Volate SR, Davenport DM, Muga SJ, Wargovich MJ. (2005). Modulation of aberrant crypt foci and apoptosis by dietary herbal supplements (quercetin, curcumin, silymarin, ginseng and rutin). Carcinogenesis 26:1450–6
  • Youle RJ, Strasser A. (2008). The BCL-2 protein family: opposing activities that mediate cell death. Nat Rev Mol Cell Biol 9:47–59

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.