381
Views
8
CrossRef citations to date
0
Altmetric
Research Article

Different regulation of aryl hydrocarbon receptor-regulated genes in response to dioxin in undifferentiated and neuronally differentiated human neuroblastoma SH-SY5Y cells

, &
Pages 689-697 | Received 18 May 2015, Accepted 30 Jun 2015, Published online: 31 Aug 2015

References

  • Agholme L, Lindstrom T, Kagedal K, et al. (2010). An in vitro model for neuroscience: differentiation of SH-SY5Y cells into cells with morphological and biochemical characteristics of mature neurons. J Alzheimers Dis 20:1069–82
  • Bradshaw TD, Bell DR. (2009). Relevance of the aryl hydrocarbon receptor (AhR) for clinical toxicology. Clin Toxicol (Phila) 47:632–42
  • Brouns RE, Bos RP, van Gemert PJ, et al. (1979). Mutagenic effects of benzo[a]pyrene after metabolic activation by hepatic 9000 g supernatants or intact hepatocytes. Mutat Res 62:19–26
  • Chang CC, Lee PS, Chou Y, et al. (2012). Mediating effects of aryl-hydrocarbon receptor and RhoA in altering brain vascular integrity: the therapeutic potential of statins. Am J Pathol 181:211–21
  • Chen YC, Guo YL, Hsu CC, Rogan WJ. (1992). Cognitive development of Yu-Cheng (“oil disease”) children prenatally exposed to heat-degraded PCBs. JAMA 268:3213–18
  • Chevallier A, Mialot A, Petit JM, et al. (2013). Oculomotor deficits in aryl hydrocarbon receptor null mouse. PLoS One 8:e53520
  • Choudhary D, Jansson I, Stoilov I, et al. (2005). Expression patterns of mouse and human CYP orthologs (families 1–4) during development and in different adult tissues. Arch Biochem Biophys 436:50–61
  • Dauchy S, Dutheil F, Weaver RJ, et al. (2008). ABC transporters, cytochromes P450 and their main transcription factors: expression at the human blood-brain barrier. J Neurochem 107:1518–28
  • Desaulniers D, Xiao GH, Leingartner K, et al. (2005). Comparisons of brain, uterus, and liver mRNA expression for cytochrome p450s, DNA methyltransferase-1, and catechol-o-methyltransferase in prepubertal female Sprague-Dawley rats exposed to a mixture of aryl hydrocarbon receptor agonists. Toxicol Sci 86:175–84
  • Dougherty EJ, Pollenz RS. (2008). Analysis of Ah receptor-ARNT and Ah receptor-ARNT2 complexes in vitro and in cell culture. Toxicol Sci 103:191–206
  • Dvorak Z, Vrzal R, Pavek P, Ulrichova J. (2008). An evidence for regulatory cross-talk between aryl hydrocarbon receptor and glucocorticoid receptor in HepG2 cells. Physiol Res 57:427–35
  • Esser C. (2012). Biology and function of the aryl hydrocarbon receptor: report of an international and interdisciplinary conference. Arch Toxicol 86:1323–9
  • Ferguson CS, Tyndale RF. (2011). Cytochrome P450 enzymes in the brain: emerging evidence of biological significance. Trends Pharmacol Sci 32:708–14
  • Galijatovic A, Beaton D, Nguyen N, et al. (2004). The human CYP1A1 gene is regulated in a developmental and tissue-specific fashion in transgenic mice. J Biol Chem 279:23969–76
  • Gassmann K, Abel J, Bothe H, et al. (2010). Species-specific differential AhR expression protects human neural progenitor cells against developmental neurotoxicity of PAHs. Environ Health Perspect 118:1571–7
  • Gim J, Kim HS, Kim J, et al. (2010). A system-level investigation into the cellular toxic response mechanism mediated by AhR signal transduction pathway. Bioinformatics 26:2169–75
  • Gramatzki D, Pantazis G, Schittenhelm J, et al. (2009). Aryl hydrocarbon receptor inhibition downregulates the TGF-beta/Smad pathway in human glioblastoma cells. Oncogene 28:2593–605
  • Gu A, Ji G, Jiang T, et al. (2012). Contributions of aryl hydrocarbon receptor genetic variants to the risk of glioma and PAH-DNA adducts. Toxicol Sci 128:357–64
  • Hao N, Bhakti VL, Peet DJ, Whitelaw ML. (2013). Reciprocal regulation of the basic helix-loop-helix/Per-Arnt-Sim partner proteins, Arnt and Arnt2, during neuronal differentiation. Nucleic Acids Res 41:5626–38
  • Hirose K, Morita M, Ema M, et al. (1996). cDNA cloning and tissue-specific expression of a novel basic helix-loop-helix/PAS factor (Arnt2) with close sequence similarity to the aryl hydrocarbon receptor nuclear translocator (Arnt). Mol Cell Biol 16:1706–13
  • Hlobilkova A, Ehrmann J, Knizetova P, et al. (2009). Analysis of VEGF, Flt-1, Flk-1, nestin and MMP-9 in relation to astrocytoma pathogenesis and progression. Neoplasma 56:284–90
  • Isom HC, Secott T, Georgoff I, et al. (1985). Maintenance of differentiated rat hepatocytes in primary culture. Proc Natl Acad Sci USA 82:3252–6
  • Jernstrom B, Graslund A. (1994). Covalent binding of benzo[a]pyrene 7,8-dihydrodiol 9,10-epoxides to DNA: molecular structures, induced mutations and biological consequences. Biophys Chem 49:185–99
  • Jiang YZ, Wang K, Fang R, Zheng J. (2010). Expression of aryl hydrocarbon receptor in human placentas and fetal tissues. J Histochem Cytochem 58:679–85
  • Jin DQ, Jung JW, Lee YS, Kim JA. (2004). 2,3,7,8-Tetrachlorodibenzo-p-dioxin inhibits cell proliferation through arylhydrocarbon receptor-mediated G1 arrest in SK-N-SH human neuronal cells. Neurosci Lett 363:69–72
  • Kamal A, Cincinelli A, Martellini T, Malik RN. (2014). A review of PAH exposure from the combustion of biomass fuel and their less surveyed effect on the blood parameters. Environ Sci Pollut Res Int 22:4076–98
  • Korashy HM, Abuohashish HM, Maayah ZH. (2013). The role of aryl hydrocarbon receptor-regulated cytochrome P450 enzymes in glioma. Curr Pharm Des 19:7155–66
  • Lawther PJ, Waller RE. (1976). Coal fires, industrial emissions and motor vehicles as sources of environmental carcinogens. IARC Sci Publ 13:27–40
  • Mandal PK. (2005). Dioxin: a review of its environmental effects and its aryl hydrocarbon receptor biology. J Comp Physiol B 175:221–30
  • Mcfayden MC, Melvin WT, Murray GI. (1998). Regional distribution of individual forms of cytochrome P450 mRNA in normal adult human brain. Biochem Pharmacol 55:825–30
  • Miller KP, Ramos KS. (2001). Impact of cellular metabolism on the biological effects of benzo[a]pyrene and related hydrocarbons. Drug Metab Rev 33:1–35
  • Moran TB, Brannick KE, Raetzman LT. (2012). Aryl-hydrocarbon receptor activity modulates prolactin expression in the pituitary. Toxicol Appl Pharmacol 265:139–45
  • Murray GI, Taylor MC, Mcfadyen MC, et al. (1997). Tumor-specific expression of cytochrome P450 CYP1B1. Cancer Res 57:3026–31
  • Pashin YV, Bakhitova LM. (1979). Mutagenic and carcinogenic properties of polycyclic aromatic hydrocarbons. Environ Health Perspect 30:185–9
  • Perera FP, Rauh V, Whyatt RM, et al. (2006). Effect of prenatal exposure to airborne polycyclic aromatic hydrocarbons on neurodevelopment in the first 3 years of life among inner-city children. Environ Health Perspect 114:1287–92
  • Pichard-Garcia L, Gerbal-Chaloin S, Ferrini JB, et al. (2002). Use of long-term cultures of human hepatocytes to study cytochrome P450 gene expression. Methods Enzymol 357:311–21
  • Pott F, Stober W. (1983). Carcinogenicity of airborne combustion products observed in subcutaneous tissue and lungs of laboratory rodents. Environ Health Perspect 47:293–303
  • Singh AK, Kashyap MP, Jahan S, et al. (2012). Expression and inducibility of cytochrome P450s (CYP1A1, 2B6, 2E1, 3A4) in human cord blood CD34(+) stem cell-derived differentiating neuronal cells. Toxicol Sci 129:392–410
  • Tripathi VK, Kumar V, Singh AK, et al. (2014). Monocrotophos induces the expression and activity of xenobiotic metabolizing enzymes in pre-sensitized cultured human brain cells. PLoS One 9:e91946
  • Tsuchiya Y, Nakajima M, Itoh S, et al. (2003). Expression of aryl hydrocarbon receptor repressor in normal human tissues and inducibility by polycyclic aromatic hydrocarbons in human tumor-derived cell lines. Toxicol Sci 72:253–9
  • Urvalek A, Laursen KB, Gudas LJ. (2014). The roles of retinoic acid and retinoic acid receptors in inducing epigenetic changes. Subcell Biochem 70:129–49
  • Vrzal R, Doricakova A, Novotna A, et al. (2011). Valproic acid augments vitamin D receptor-mediated induction of CYP24 by vitamin D3: a possible cause of valproic acid-induced osteomalacia? Toxicol Lett 200:146–53
  • Whalley K, Gogel S, Lange S, Ferretti P. (2009). Changes in progenitor populations and ongoing neurogenesis in the regenerating chick spinal cord. Dev Biol 332:234–45
  • Wu ML, Li H, Wu DC, et al. (2005). CYP1A1 and CYP1B1 expressions in medulloblastoma cells are AhR-independent and have no direct link with resveratrol-induced differentiation and apoptosis. Neurosci Lett 384:33–7
  • Yun CH, Park HJ, Kim SJ, Kim HK. (1998). Identification of cytochrome P450 1A1 in human brain. Biochem Biophys Res Commun 243:808–10
  • Zuchegna C, Aceto F, Bertoni A, et al. (2014). Mechanism of retinoic acid-induced transcription: histone code, DNA oxidation and formation of chromatin loops. Nucleic Acids Res 42:11040–55
  • Zuo J, Brewer DS, Arlt VM, et al. (2014). Benzo pyrene-induced DNA adducts and gene expression profiles in target and non-target organs for carcinogenesis in mice. BMC Genomics 15:880

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.