Immunotoxicity in mice induced by short-term exposure to methoxychlor, parathion, or piperonyl butoxide

References

• Anderson, S. E., Munson, A. E., Meade, B. J. 2006. Analysis of immunotoxicity by enumeration of antibody-producing B cells. In: Current Protocols in Toxicology. Unit 18.11. (Bus, J. S., Costa, L. G., Hodgson, E., Lawrence, D. A.Reed, D., Eds.). Hoboken, NJ: John Wiley and Sons, pp. 1–18.
   Google Scholar
• Battaglia, C. L., Gogal, R. M. Jr., Zimmerman, K., Misra, H. P. 2010. Malathion, lindane, and piperonyl butoxide, individually or in combined mixtures, induce immunotoxicity via apoptosis in murine splenocytes in vitro. Int. J. Toxicol. 29:209–220.
   PubMed Web of Science ®Google Scholar
• Carson, D. S., Tribble, P. W., Weart, C. W. 1988. Pyrethrins combined with piperonyl butoxide (RID) vs. 1% permethrin (NIX) in the treatment of head lice. Am. J. Dis. Child. 142:768–769.
   PubMedGoogle Scholar
• Casale, G. P., Cohen, S. D., DiCapua, R. A. 1984. Parathion-induced suppression of humoral immunity in inbred mice. Toxicol. Lett. 23:239–247.
   PubMed Web of Science ®Google Scholar
• Committee on Proprietary Medicinal Products. 2000. Note for Guidance on Repeat-Dose Toxicity, CPMP/SWP/1042/99. Available online at: http://www.emea.eu.int.
   Google Scholar
• Cunningham, A. J. 1965. A method of increased sensitivity for detecting single antibody-forming cells. Nature 207:1106–1107.
   PubMed Web of Science ®Google Scholar
• Diel, F., Horr, B., Borck, H., Savtchenko, H., Mitsche, T., Diel, E. 1999. Pyrethroids and piperonyl-butoxide affect human T-lymphocytes in vitro. Toxicol. Lett. 107:65–74.
   PubMed Web of Science ®Google Scholar
• Emerson, M. R., Biswas, S., LeVine, S. M. 2001. Cuprizone and piperonyl butoxide, proposed inhibitors of T-cell function, attenuate experimental allergic encephalomyelitis in SJL mice. J. Neuroimmunol. 119:205–213.
   PubMedGoogle Scholar
• EPA. 1998. United States Environmental Protection Agency. Health Effects Test Guidelines: Immunotoxicity. 1998, OPPTS 870.7800. Available online at:http://www.epa.gov/opptsfrs/publications.
   Google Scholar
• EPA. 2003. United States Environmental Protection Agency. Office of Research and Development. Human Health Research Strategy (PUB EPA/600/R-02/050). Washington, DC: US EPA, 2003.
   Google Scholar
• FDA.2002. United States Food and Drug Administration. Guidance for Industry: Immunotoxicology Evaluation of Investigational New Drugs. Available online at:http://www.fda.gov/cder/guidance.
   Google Scholar
• Fukuyama, T., Kosaka, T., Tajima, Y., Hayashi, K., Shutoh, Y., Harada, T. 2011a. Detection of thymocytes apoptosis in mice induced by organochlorine pesticides methoxychlor. Immunopharmacol. Immunotoxicol. 33:193–200.
   PubMed Web of Science ®Google Scholar
• Fukuyama, T., Tajima, Y., Ueda, H., Hayashi, K., Kosaka, T. 2011b. Prior exposure to immunosuppressive organophosphorus or organochlorine compounds aggravates the TH1- and TH2-type allergy caused by topical sensitization to 2,4-dinitrochlorobenzene and trimel-litic anhydride. J. Immunotoxicol. 8:170–182.
   PubMed Web of Science ®Google Scholar
• Fukuyama, T., Tajima, Y., Ueda, H., Hayashi, K., Shutoh, Y., Harada, T., Kosaka, T. 2010. Apoptosis in immunocytes induced by several types of pesticides. J. Immunotoxicol. 7:39–56.
   PubMed Web of Science ®Google Scholar
• Gurtu, V., Kain, S. R., Zhang, G. 1997. Fluorometric and colorimetric detection of caspase activity associated with apoptosis. Anal. Biochem. 251:98–102.
   PubMed Web of Science ®Google Scholar
• Herzyk, D. J., Holsapple, M. 2007. Immunotoxicity evaluation by immune function tests: Focus on the T-dependent antibody response (TDAR). J. Immunotoxicol. 4:143–147.
   PubMed Web of Science ®Google Scholar
• ICH. 2006. International Conference on harmonization of technical requirements for registration of pharmaceuticals for human use. ICH Harmonised Tripartite Guideline Immunotoxicity Studies For Human Pharmaceuticals S8. Switzerland. ICH.
   Google Scholar
• Janeway, C. A., Travers, P., Walport, M., Shlomchik, M. J. (Eds.) 2004. Immunobiology, 6th Edition. New York: Garland Science.
   Google Scholar
• Jerne, N. K., Nordin, A. A. 1963. Plaque formation in agar by single antibody-producing cells. Science 140:405.
   Web of Science ®Google Scholar
• Kamath, A. B., Xu, H., Nagarkatti, P. S., Nagarkatti, M. 1997. Evidence for the induction of apoptosis in thymocytes by 2,3,7,8-tetrachlorodibenzo-p-dioxin in vivo. Toxicol. Appl. Pharmacol. 142:367–377.
   PubMed Web of Science ®Google Scholar
• Ladics, G. S., Smith, C., Elliott, G. S., Slone, T. W., Loveless, S. E. 1998. Further evaluation of incorporation of an immunotoxicological functional assay for assessing humoral immunity for hazard identification purposes in rats in a standard toxicology study. Toxicology 126:137–152.
   PubMed Web of Science ®Google Scholar
• Lowry, O. H., Rosebrough, N. J., Farr, A. L., Randall, R. J. 1951. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193:265–275.
   PubMed Web of Science ®Google Scholar
• Mitsumori, K., Takegawa, K., Shimo, T., Onodera, H., Yasuhara, K., Takahashi, M. 1996. Morphometric and immunohistochemical studies on atrophic changes in lymphohematopoietic organs of rats treated with piperonyl butoxide or subjected to dietary restriction. Arch. Toxicol. 70:809–814.
   PubMed Web of Science ®Google Scholar
• Morris, R. G., Hargreaves, A. D., Duvall, E., Wyllie, A. H. 1984. Hormone-induced cell death. 2. Surface changes in thymocytes undergoing apoptosis. Am. J. Pathol. 115:426–436.
   PubMed Web of Science ®Google Scholar
• Pryputniewicz, S. J., Nagarkatti, M., Nagarkatti, P. S. 1998. Differential induction of apoptosis in activated and resting T-cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and its repercussion on T-cell responsiveness. Toxicology 129:211–226.
   PubMed Web of Science ®Google Scholar
• Registry of Toxic Effects of Chemical Substances NIOSH CD-ROM (2003).
   Google Scholar
• Savill, J., Haslett, C. 1995. Granulocyte clearance by apoptosis in the resolution of inflamemation. Semin. Cell Biol. 6:385–933.
   PubMedGoogle Scholar
• Shinall, S. M., Gonzalez-Fernandez, M., Noelle, R. J., Waldschmidt, T. J. 2000. Identification of murine germinal center B-cell subsets defined by the expression of surface isotypes and differentiation antigens. J. Immunol. 164:5729–5738.
   PubMedGoogle Scholar
• Takahashi, Y., Dutta, P. R., Cerasoli, D. M., Kelsoe, G. 1998. In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. V. Affinity maturation develops in two stages of clonal selection. J. Exp. Med. 187:885–895.
   PubMed Web of Science ®Google Scholar
• Takeuchi, Y., Kosaka, T., Hayashi, K., Ishimine, S., Ohtsuka, R., Kuwahara, M., Yoshida, T., Takahashi, N., Takeda, M., Maita, K., Harada, T. 2004. Alterations in the developing immune system of the rat after perinatal exposure to methoxychlor. J. Toxicol. Pathol. 17:165–170.
   Google Scholar
• Takeuchi, Y., Kosaka, T., Hayashi, K., Takeda, M., Yoshida, T., Fujisawa, H., Teramoto, S., Maita, K., Harada, T. 2002. Thymic atrophy induced by methoxychlor in rat pups. Toxicol. Lett. 135:199–207.
   PubMed Web of Science ®Google Scholar
• Temple, L., Kawabata, T. T., Munson, A. E., White, K. L. Jr. 1993. Comparison of ELISA and plaque-forming cell assays for measuring the humoral immune response to SRBC in rats and mice treated with benzo[a]pyrene or cyclophosphamide. Fundam. Appl. Toxicol. 21:412–419.
   PubMedGoogle Scholar
• Vermes, I., Haanen, C., Steffens-Nakken, H., Reutelingsperger, C. 1995. A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein-labeled Annexin V. J. Immunol. Meth. 184:39–51.
   PubMed Web of Science ®Google Scholar
• Vieira, P., Rajewsky, K. 1990. Persistence of memory B-cells in mice deprived of T cell help. Int. Immunol. 2:487–494.
   PubMed Web of Science ®Google Scholar
• White, K. L., Musgrove, D. L., Brown, R. D. 2010. The sheep erythrocyte T-dependent antibody response (TDAR). Methods Mol. Biol. 598:173–184.
   PubMedGoogle Scholar
• Zhang, N., Hartig, H., Dzhagalov, I., Draper, D., He, Y. W. 2005. The role of apoptosis in the development and function of T-lymphocytes. Cell Res. 15:749–769.
   PubMed Web of Science ®Google Scholar