References
- Adkinson N. F. Jr., Essayan, D., Gruchalla, R., et al, the Health & Environmental Sciences Institute Task Force. 2002. Task force report: Future research needs for the prevention and management of immune-mediated drug hypersensitivity reactions. J. Allergy Clin. Immunol. 109:S461–S478
- Bachmann, M. F., Wolint, P., Schwarz, K., et al. 2005. Functional properties and lineage relationship of CD8+ T-cell subsets identified by expression of IL-7 receptor alpha and CD62L. J. Immunol. 175:4686–4696
- Bloksma, N., Kubicka-Muranyi, M., Schuppe, H. C., et al. 1995. Predictive immunotoxicological test systems: Suitability of the popliteal lymph node assay in mice and rats. Crit. Rev. Toxicol. 25:369–396
- Calabresi, P. A., Allie, R., Mullen, K. M., et al. 2003. Kinetics of CCR7 expression differ between primary activation and effector memory states of TH1 and TH2 cells. J. Neuroimmunol. 139:58–65
- Chao, C. C., Jensen, R., and Dailey, M. O. 1997. Mechanisms of L-selectin regulation by activated T-cells. J. Immunol. 159:1686–1694
- Cose, S. C., Joens, C. M., Wallace, M. E., et al. 1997. Antigen-specific CD8+ T-cell subset distribution in lymph nodes draining the site of herpes simplex virus infection. Eur. J. Immunol. 27:2310–2316
- Daoussis, D., Andonopoulos, A. P., and Liossis, S. N. 2004. Targeting CD40L: A promising therapeutic approach. Clin. Diagn. Lab. Immunol. 11:635–641
- Elgueta, R., Benson, M. J., de Vries, V. C., et al. 2009. Molecular mechanism and function of CD40/CD40L engagement in the immune system. Immunol. Rev. 229:152–172
- Finlay, D., and Cantrell, D. A. 2011. Metabolism, migration and memory in cytotoxic T-cells. Nat. Rev. Immunol. 11:109–117
- Forster, R., Davalos-Misslitz, A. C., and Rot, A. 2008. CCR7 and its ligands: Balancing immunity and tolerance. Nat. Rev. Immunol. 8:362–371
- Forster, R., Schubel, A., Breitfeld, D., et al. 1999. CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs. Cell 99:23–33
- Gerdes, J., Lemke, H., Baisch, H., et al. 1984. Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67. J. Immunol. 133:1710–1715
- Gomes, E. R., and Demoly, P. 2005. Epidemiology of hypersensitivity drug reactions. Curr. Opin. Allergy Clin. Immunol. 5:309–316
- Inchley, C. J. 1987. The contribution of B-cell proliferation to spleen enlargement in Babesia microti-infected mice. Immunology 60:57–61
- Jung, K. M., Jang, W. H., Lee, Y. K., et al. 2012. B-Cell increases and ex vivo IL-2 production as secondary end-points for the detection of sensitizers in non-radioisotopic local lymph node assay using flow cytometry. Toxicol. Lett. 209:255–263
- Kimber, I., Dearman, R. J., Basketter, D. A., et al. 2002. The local lymph node assay: Past, present and future. Contact Dermatitis 47:315–328
- Larsen, J. M., Geisler, C., Nielsen, M. W., et al. 2007. Cellular dynamics in the draining lymph nodes during sensitization and elicitation phases of contact hypersensitivity. Contact Dermatitis 57:300–308
- Lee, J. K., Hee Park, S., Byun, J. A., et al. 2004. Evaluation of lymphocyte subpopulations in draining lymph node cells following allergen and irritant. Environ. Toxicol. Pharmacol. 17:95–102
- Liu, Q., Chen, T., Chen, G., et al. 2007. Triptolide impairs dendritic cell migration by inhibiting CCR7 and COX-2 expression through PI3-K/Akt and NF-κB pathways. Mol. Immunol. 44:2686–2696
- Mackay, C. R., Marston, W., and Dudler, L. 1992. Altered patterns of T-cell migration through lymph nodes and skin following antigen challenge. Eur. J. Immunol. 22:2205–2210
- Manetz, T. S., and Meade, B. J. 1999. Development of a flow cytometry assay for the identification and differentiation of chemicals with the potential to elicit irritation, IgE-mediated, or T-cell-mediated hypersensitivity responses. Toxicol. Sci. 48:206–217
- Masopust, D., and Schenkel, J. M. 2013. The integration of T-cell migration, differentiation, and function. Nat. Rev. Immunol. 13:309–320
- Mauri C., and Bosma, A. 2012. Immune regulatory function of B-cells. Annu. Rev. Immunol. 30:221–241
- Noor, S., Habashy, A. S., Nance, J. P., et al. 2010. CCR7-dependent immunity during acute Toxoplasma gondii infection. Infect. Immun. 78:2257–2263
- Payan, D. G., Brewster, D. R., and Goetzl, E. J. 1983. Specific stimulation of human T-lympho-cytes by substance P. J. Immunol. 131:1613–1615
- Rot, A., and von Andrian, U. H. 2004. Chemokines in innate and adaptive host defense: Basic chemokinese grammar for immune cells. Annu. Rev. Immunol. 22:891–928
- Sikorski, E. E., Gerberick, G. F., Ryan, C. A., et al. 1996. Phenotypic analysis of lymphocyte subpopulations in lymph nodes draining the ear following exposure to contact allergens and irritants. Fundam. Appl. Toxicol. 34:25–35
- Sordi, V., Bianchi, G., Buracchi, C., et al. 2006. Differential effects of immunosuppressive drugs on chemokine receptor CCR7 in human monocyte-derived dendritic cells: Selective upregulation by rapamycin. Transplantation 82:826–834
- Thong, B. Y., and Tan, T. C. 2011. Epidemiology and risk factors for drug allergy. Br. J. Clin. Pharmacol. 71:684–700
- von Andrian, U. H., and Mempel, T. R. 2003. Homing and cellular traffic in lymph nodes. Nat. Rev. Immunol. 3:867–878
- Weaver, J. L., Chapdelaine, J. M., Descotes, J., et al. 2005. Evaluation of a lymph node proliferation assay for its ability to detect pharmaceuticals with potential to cause immune-mediated drug reactions. J. Immunotoxicol. 2:11–20
- Whritenour, J., Cole, S., Zhu, X., et al. 2014. Development and partial validation of a mouse model for predicting drug hypersensitivity reactions. J. Immunotoxicol. 11:141–147
- Wiede, F., Roomberg, A., Cretney, E., et al. 2009. Age-dependent, polyclonal hyperactivation of T-cells is reduced in TNF-negative gld/gld mice. J. Leukocyte Biol. 85:108–116
- Woolhiser, M. R., Munson, A. E., and Meade, B. J. 2000. Comparison of mouse strains using the local lymph node assay. Toxicology 146:221–227