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Research Article

The Cardiac Toxicity of Noncardiac Drugs and Other Agents in Toxicity Tests on Laboratory Animals at Queen's University between 1958 and 1968

Pages 221-232 | Published online: 25 Sep 2008

References

  • Boyd E. M. ldquo;The Acute Oral Toxicity of Acetylsalicylic Acid”. Toxicol. Appl. Pharmacol. 1959; 1: 229–239
  • Boyd E. M. The Acute Oral Toxicity in Guniea Pigs of Acetylsalicylic Acid, Phenacetin, and Caffeine, Alone and Combined. Toxicol. Appl. Pharmacol. 1960; 2: 23–32
  • Coldwell B. B., Boyd E. M. The Acute Rectal Toxicity of Acetylsalicylic Acid. Can. J. Physiol. Pharmacol. 1966; 44: 909–918
  • Boyd E. M. The Acute Oral Toxicity of a Mixture of Acetylsalicylic Acid, Phencetin, and Caffeine. Toxicol. Appl. Pharmacol. 1959; 1: 258–266
  • Boyd E. M., Boyd C. E. The Acute Toxicity of Atropine Sulfate. Can. Med. Assoc. J. 1961; 85: 1241–1244
  • Boyd E. M., Abel M. ldquo;The Acute Toxicity of Barium Sulfate Administered Intragastrically”. Can. Med. Assoc. J. 1966; 94: 849–853
  • Boyd E. M., Broughton R. J., James J. The Acute Oral Toxicity of Benzylpenicillin Ammonium. Antibiot. Chemotherapy 1959; 9: 739–743
  • Boyd E. M., Broughton R. J., James J. ldquo;The Acute Oral Toxicity of Benzylpenicillin Potassium”. Arch. Intern. Pharmacodyn. 1960; 123: 295–304
  • Boyd C. E. ldquo;The Acute Oral Toxicity of Benzylpenicillin Potassium in the Rabbit”. Antibiot. Chemotherapy 1960; 10: 376–384
  • Boyd E. M., Fulford R. A. ldquo;The Acute Oral Toxicity of Benzylpenicillin Potassium in Guinea pigs”. Antibiot. Chemotherapy 1961; 11: 276–283
  • Boyd E. M., Godi I., Krijnen C. J. The Acute Oral Toxicity of a Vasicin Derivative. J. New. Drugs 1966; 6: 269–277
  • Boyd E. M. ldquo;The Acute Oral Toxicity of Caffeine”. Toxicol. Appl. Pharmacol. 1959; 1: 250–257
  • Boyd E. M., Krijnen C. J. ldquo;Toxicity of Captan and Protein-Deficient Diet”. J. Clin. Pharmacol. 1968; 8: 225–234
  • Boyd E. M., Boulanger M. A. ldquo;Insecticide Toxicity: Augmented Susaptibility to Carbaryl Toxicity in Albino Rats Fed Purified Casein Diets”. Agr. Food. Chem. 1968; 16: 834–838
  • Boyd F. M., Krijnen C. J., Peters J. M. Lethal Amounts of Casein, Casein Salts and Hydrolyzed Casein Given Orally to Albino Rats. J. Nurr. 1967; 93: 429–437
  • Boyd E. M., Boulanger M. A., Carsky E. ldquo;The Acute Oral Toxicity of Corn Oil”. J. Clin. Pharmacol 1969; 9: 137–147
  • Boyd E. M., Boulanger M. A. ldquo;Acute Oral Toxicity of Cottonseed Oil”. Toxicol. Appl. Pharmacol. 1969; 14: 432–438
  • Boyd E. M., De E. S. Castro Protein-Deficient Diet and DDT Toxicity. Bull. World Health Organ. 1968; 38: 141–150
  • Boyd E. M., Peters J. M., Krijnen C. J. ldquo;The Acute Oral Toxicity of Reconstituted Spray-Dried Egg White”. Ind. Med. Surg. 1966; 35: 782–787
  • Boyd E. M., Dobos I. ldquo;Protein Deficiency and Tolerated Oral Doses of Endosulfan”. Arch. Intern. Pharmacodyn. 1969; 178: 152–165
  • Boyd E. M., Carsky E. Maximal Tolerated Amounts of Dextrose Given Intragastrically to Albino Rats. Acta Diabet. Lat. 1967; IV: 538–549
  • Boyd E. M., Shanas M. N. ldquo;The Acute oral Toxicity of Reduced iron”. Can. Med. Assoc. J. 1963; 89: 171–175
  • Boyd E. M., Covert E. L., Shasas M. N. ldquo;Death from Bowel Obstruction Due to Intragastrically Administered Kaolin”. Ind. Med. Surg. 1965; 34: 874–880
  • Boyd E. M., Chen C. P. ldquo;Lindane Toxicity and Protein-Deficient Diet”. Arch. Environ. Health 1968; 17: 156–163
  • Boyd E. M., Tanikella T. K. The Acute Oral Toxicity of Malathion in Relation to Dietary Protein. Arch. Toxikol. 1969; 24: 292–303
  • Boyd E. M., Berezky G. M. ldquo;Liver Necrosis from Paracetamol”. Brit. J. Pharmacol. Chemotherapy 1966; 26: 606–614
  • Boyd E. M. The Acute Oral Toxicity of Phenacetin. Toxicol. Appl. Pharmacol. 1959; 1: 240–249
  • Boyd E. M., Fulford R. A. Pilocarpine-Induced Convulsions and Delayed Psychotic-like Reaction. Can. J. Biochem. Physiol. 1961; 39: 1287–1294
  • Boyd E. M., Shanas M. N. ldquo;The Acute Oral Toxicity of Potassium Chloride”. Arch. Intern. Pharmacodyn. 1961; 133: 275–283
  • Boyd E. M. The Acute Subcutaneous Toxicity of Spiramycin Adipate in Albino Rats. Antibiot. Ann. 1957–1958; 842–85L
  • Boyd E. M., Price-Jones M. A. ldquo;The Acute Subcutaneous Toxicity of Spirmycin Adipate in Cats”. Antibiot. Chemotherpy 1959; 9: 353–357
  • Boyd E. M., Shanas M. N. ldquo;The Acute Oral Toxicity of Sodium Chloride”. Arch. Intern. Pharmacodyn. 1963; 144: 86–96
  • Boyd E. M., Godi I., Abel M. ldquo;Acute Oral Toxicity of Sucrose”. Toxicol. Appl. Pharmacol. 1965; 7: 609–618
  • Boyd E. M., Bereczky K., Godi I. ldquo;The Acute Toxicity of Tannic Acid Administered Intragastrically”. Can. Med. Assoc. J. 1965; 92: 1292–1297
  • Singh J., Boyd E. M. The Acute Toxicity of Tannic Acid in the Tannic Acid-Barium Sulfate Radiodiagnostic Enema. J. Can. Assoc. Radiol. 1966; 17: 124–131
  • Boyd E. M., Godi I. ldquo;Acute Oral Toxicity of Distilled Water in Albino Rats”. Ind. Med. Surg. 1967; 36: 609–613
  • Boyd E. M. ldquo;Analgesic Abuse: Maximal Tolerated Daily Doses of Acetylsalicylic Acid”. Can. Med. Assoc. J. 1968; 99: 790–798
  • Peters J. M. ldquo;Organ Weights and Water Contents of Fully Grown Female Rats”. Toxical. Appl. Pharmacol. 1967; 10: 21–26
  • Boyd E. M., Jarzylo S. V. ldquo;Chronic Atropinization and Fibrocystic Disease of the Pancreas”. Can. Med. Assoc. J. 1960; 82: 821–824
  • Boyd E. M., Boyd C. E. ldquo;The Chronic Toxicity of Atropine Administered Intramuscularly to Rabbits”. Toxicol. Appl. Pharmacol. 1962; 4: 457–467
  • Mills D. W. ldquo;Studies on the Chronic Oral Toxicity of Potassium Penicillin G”. Arch. Intern. Pharmacodyn. 1960; 125: 83–95
  • Boyd E. M., Selby M. J. The Chronic Oral Toxicity of Benzylpenillin. Antibiot. Chemotherapy. 1962; 12: 249–262
  • Boyd E. M., Sargeant M. J. ldquo;The Production of Skin Reactions to Benzylpenicillin in Animals on a Biotin-Deficient Diet”. J. New Drugs 1962; 2: 283–291
  • Boyd E. M., Dolman M., Knight L. M., Sheppard E. P. ldquo;The Chronic Oral Toxicity of Caffeine”. Can. J. Physiol. Pharmacol. 1965; 43: 995–1007
  • Peters J. M. ldquo;Caffeine Toxicity in Starved Rats”. Toxicol. Appl. Pharmacol 1966; 9: 390–397
  • Boyd E. M., Covert E. L., Pitman C. A. ldquo;Benzylpenicillin Toxicity in Albino Rats Fed Synthetic High Sugar Diets”. Chemotherapy 1966; 11: 320–330
  • Peters J. M. ldquo;A Separation of the Direct Toxic Effects of Dietary Raw Egg White Powder from Its Action in Producing Biotin Deficiency”. Brit. J. Nutr. 1967; 21: 801–809
  • Peters J. M., Krijnen C. J. ldquo;Organ Weights and Water Contents of Lactating Rats”. Growth 1966; 30: 295–303
  • Boyd E. M., Mutrooney D. A., Pitman C. A., Abel M. ldquo;Benzylpenicillin Toxicity in Animals on a Synthetic High Sucrose Diet”. Can. J. Physiol. Pharmacol. 1965; 43: 47–54
  • Boyd E. M., Hogan S. E. ldquo;The Chronic Oral Toxicity of Paracetamol at the Range of the LD50 (100 days) in Albino Rats”. Can. J. Physiol. Pharmacol. 1968; 12: 239–245
  • Boyd E. M., Hottenroth S. M. H. ldquo;The Toxicity of Phenacetin at the Range of the Oral LD50(100 days) in Albino Rats”. Toxicol. Appl. Pharmacol. 1968; 12: 80–93
  • Boyd E. M., Jarzylo S. V. ldquo;Daily Oral Doses of Pilocarpine Tolerated by Albino Rats”. Arch. Intern. Pharmacodyn. 1968; 175: 84–98
  • Peters J. M., Krijnen C. J., Boyd E. M. ldquo;Role of Concepta in the producation of Hypertrophy and Hydration of Maternal Body Organs in the Third Week of Pregnancy in Albino Rats”. J. Reprod. Fert. 1967; 14: 235–242
  • De Castro E. S., Boyd E. M. ldquo;Organ Weights and Water Content of Rats Fed Protein-Deficient Diets”. Bull. World Health Organ. 1968; 38: 971–977
  • Boyd E. M., Abel M. M., Knight L. M. The Chronic Oral Toxicity of Sodium Chloride at the Range of the LD50(0.1L). Can. J. Physiol. Pharmacol. 1966; 44: 157–172
  • Boyd E. M., Brown T. M. D. ldquo;Chronic Subcutaneous Toxicity of Spiramycin Adipate”. Can. Med. Assoc. J. 1958; 78: 671–674
  • Boyd E. M., Jarzylo S. V., Boyd C. E., Cassell W. A. ldquo;Chornic Oral Toxicity of Spiramycin in Dogs”. Arch. Intern. Pharmacodyn. 1958; 115: 360–371
  • Boyd E. M., Liu S. J. ldquo;Toxicity of Starch Administered by Mouth”. Can. Med. Assoc. J. 1968; 98: 492–499
  • Peters J. M. ldquo;Effects of Absolute Starvation and Refeeding on Organ Weights and Water Contents of Albino Rats”. Growth 1967; 31: 191–203
  • Peters J. M., Boyd E. M. Organ Weights and Water Levels of the Rat Following Reduced Food Intake. J. Nutr. 1966; 90: 354–360
  • Peters J. M., Boyd E. M. Organ Weights and Water Contents During Acute Starvation, Thirst and Stress. Growth 1968; 32: 283–296
  • Constantopoulos G., Boyd E. M. Maximal Tolerated Amounts of Surose Given by Daily Intragastric Administration to Albino Rats. Food Cosmet, Toxicol. 1968; 6: 717–727
  • Peters J. M., Krijnen C. J. ldquo;Organ Weights and Water Contents of Rats Fed Diets”. Growth 1966; 30: 99–107
  • Boyd E. M., Mulrooney D. A., Sargeant E. J. The Toxicity of Benzylpencillin in Animals on Vitamin A Deficient Test Diet, U.S.P. XIV. Can. J. Biochem. Physiol. 1962; 40: 1685–1692
  • Boyd E. M. ldquo;Ascorbic Acid and Benzylpencillin Toxicity”. Clin. Med. 1963; 70: 2223–2229

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