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Journal of Toxicology: Clinical Toxicology Volume 19, 1982 - Issue 10
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Research Article

Excessive Ingestion of Fluoride and the Significance of Sialic Acid: Glycosaminoglycans in the Serum of Rabbit and Human Subjects

Mohan Jha Fluorosis Research Laboratory Department of Anatomy, All India Institute of Medical Sciences, New Delhi, 110029, India
,
A. K. Susheela Fluorosis Research Laboratory Department of Anatomy, All India Institute of Medical Sciences, New Delhi, 110029, India
,
Neelam Krishna Institute of Preventive Medicine, Hyderabad, Andhra Pradesh, India
,
K. Rajyalakshmi Institute of Preventive Medicine, Hyderabad, Andhra Pradesh, India
&
K. Venkiah Department of Biochemistry Gandhi Medical College, Hyderabad, Andhra Pradesh, India
Pages 1023-1030 | Published online: 25 Sep 2008

References

  • Susheela A. K., Jha M. Effects of fluoride on glycosaminoglycans of cancellous and cortical bone of rabbits. Experientia 1981; 37: 1097–1099
  • Jha M., Susheela A. K. In vivo chondrogenesis and histochemical appearance of dermatan sulphate in rabbit cancellous bone. Differentiation 1982; 22: 235
  • Jha M., Susheela A. K. Characterization of glycosaminoglycans from normal and fluoride treated rabbit iliac crest. Biochem. Biophys. Res. Commun. 1982; 105: 711–716
  • Susheela A. K., Jha M. Effect of fluoride on sialic acid content of bone and serum. IRCS Med. Sci. Biochem. 1981; 9: 898
  • Hall L. L., Smith F. A., De Lopes O. H., Gardner D. E. Direct potentiometric determination of total ionic fluoride in biological fluids. Clin. Chem. 1972; 18: 1455–1458
  • Winzler R. J. Determination of serum glycoproteins. Methods in Biochemical Analysis, D. Glick. Wiley‐Interscience, New York 1961; Vol. 2: 298
  • Gold E. W. A simple spectrophotometric method for estimating GAG. Anal. Biochem. 1979; 99: 183–188
  • Susheela A. K., Sharma Y. D., Jha M., Rajyalakshmi K., Rama Mohana Rao N. V. Chemical profile of human serum in fluoride toxicity and fluorosis I. Total protein bound carbohydrates, seromucoid and fluoride levels. Fluoride 1981; 14: 150–154
  • William F. A., Peacock A. R. Binding of calcium and yttrium to a glycoprotein from bovine cortical bone. Biochem. J. 1967; 105: 1177
  • Chiferfield A. R. Calcium ion binding by bone mucosubstance. Biochem. J. 1970; 118: 36P
  • Susheela A. K., Jha M. Effect of fluoride ingestion on cortical and cancellous bone composition. IRCS Med. Sci. Biochem. 1981; 9: 1021–1022
  • Badin J., Schubbert M., Vouras M. Plasma polysaccharides fraction containing uronic acid in normal subjects and in patients with rheumatoid arthritis. J. Clin. Invest. 1955; 34: 1317–1323
  • Susheela A. K., Jha M., Singh M., Jagannath B. Excessive ingestion of fluoride and 35S‐sulphate uptake in rabbits by calcified and non‐calcified tissues with special reference to proteoglycans, Submitted for Publication

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