Heme oxygenase expression as a biomarker of exposure to amphiphilic polymer-coated CdSe/ZnS quantum dots

References

• Akerman ME, Chan WC, Laakkonen P, Bhatia SN, Ruoslahti E2002. Nanocrystal targeting in vivo. Proc Natl Acad Sci USA 99:12617–12621.
   PubMed Web of Science ®Google Scholar
• Bagalkot V, Gao X2011. siRNA-aptamer chimeras on nanoparticles: preserving targeting functionality for effective gene silencing. ACS Nano 25:8131–8139.
   Google Scholar
• Ballou B, Lagerholm BC, Ernst LA, Bruchez MP, Waggoner AS2004. Noninvasive imaging of quantum dots in mice. Bioconjug Chem 15:79–86.
   PubMed Web of Science ®Google Scholar
• Botta D, Franklin CC, White CC, Krejsa CM, Dabrowski MJ, Pierce RH, 2004. Glutamate-cysteine ligase attenuates TNF-induced mitochondrial injury and apoptosis. Free Radic Biol Med 37:632–642.
   PubMedGoogle Scholar
• Botta D, Shi S, White CC, Dabrowski MJ, Keener CL, Srinouanprachanh SL, 2006. Acetaminophen-induced liver injury is attenuated in male glutamate-cysteine ligase transgenic mice. J Biol Chem 281:28865–28875.
   PubMed Web of Science ®Google Scholar
• Chen H, Wang L, Gong T, Yu Y, Zhu C, Li F, 2010. EGR-1 regulates Ho-1 expression induced by cigarette smoke. Biochem Biophys Res Commun 396:388–393.
   PubMedGoogle Scholar
• Cho SJ, Maysinger D, Jain M, Rder B, Hackbarth S, Winnik FM2007. Long-term exposure to CdTe quantum dots causes functional impairments in live cells. Langmuir 23:1974–1980.
   PubMed Web of Science ®Google Scholar
• Clift MJ, Bhattacharjee S, Brown DM, Stone V2010a. The effects of serum on the toxicity of manufactured nanoparticles. Toxicol Lett 198:358–365.
   PubMed Web of Science ®Google Scholar
• Clift MJ, Boyles MS, Brown DM, Stone V2010b. An investigation into the potential for different surface-coated quantum dots to cause oxidative stress and affect macrophage cell signalling in vitro. Nanotoxicology 4:139–149.
   PubMed Web of Science ®Google Scholar
• Clift MJ, Gehr P, Rothen-Rutishauser B2010c. Nanotoxicology: a perspective and discussion of whether or not in vitro testing is a valid alternative. Arch Toxicol; in press.
   PubMedGoogle Scholar
• Clift MJ, Rothen-Rutishauser B, Brown DM, Duffin R, Donaldson K, Proudfoot L, 2008. The impact of different nanoparticle surface chemistry and size on uptake and toxicity in a murine macrophage cell line. Toxicol Appl Pharmacol 232:418–427.
   PubMed Web of Science ®Google Scholar
• Clift MJ, Varet J, Hankin SM, Brownlee B, Davidson AM, Brandenberger C, 2010d. Quantum dot cytotoxicity in vitro: an investigation into the cytotoxic effects of a series of different surface chemistries and their core/shell materials. Nanotoxicology 5:664–674.
   PubMedGoogle Scholar
• Fischer HC, Hauck TS, Gomez-Aristizabal A, Chan WC2010. Exploring primary liver macrophages for studying quantum dot interactions with biological systems. Adv Mater 22:1–5.
   Google Scholar
• Franklin CC, Backos DS, Mohar I, White CC, Forman HJ, Kavanagh TJ2009. Structure, function, and post-translational regulation of the catalytic and modifier subunits of glutamate cysteine ligase. Mol Aspects Med 30:86–98.
   PubMed Web of Science ®Google Scholar
• Gao X, Cui Y, Levenson RM, Chung LW, Nie S2004. In vivo cancer targeting and imaging with semiconductor quantum dots. Nat Biotechnol 22:969–976.
   PubMed Web of Science ®Google Scholar
• Geys J, Nemmar A, Verbeken E, Smolders E, Ratoi M, Hoylaerts MF, 2008. Acute toxicity and prothrombotic effects of quantum dots: impact of surface charge. Environ Health Perspect 116:1607–1613.
   PubMed Web of Science ®Google Scholar
• Gopee NV, Roberts DW, Webb P, Cozart CR, Siitonen PH, Warbritton AR, 2007. Migration of intradermally injected quantum dots to sentinel organs in mice. Toxicol Sci 98:249–257.
   PubMed Web of Science ®Google Scholar
• Gozzelino R, Jeney V, Soares MP2010. Mechanisms of cell protection by heme oxygenase-1. Annu Rev Pharmacol Toxicol 50:323–354.
   PubMed Web of Science ®Google Scholar
• Green M, Howman E2005. Semiconductor quantum dots and free radical induced DNA nicking. Chem Commun 7:121–123.
   Google Scholar
• Gunness P, Aleksa K, Koren G2010. The effect of acyclovir on the tubular secretion of creatinine in vitro. J Transl Med 8:139.
   PubMedGoogle Scholar
• Hardman R2006. A toxicologic review of quantum dots: toxicity depends on physicochemical and environmental factors. Environ Health Perspect 114:165–172.
   PubMed Web of Science ®Google Scholar
• Hauck TS, Anderson RE, Fischer HC, Newbigging S, Chan WC2010. In vivo quantum-dot toxicity assessment. Small 6:138–144.
   PubMed Web of Science ®Google Scholar
• Hu X, Gao X2010. Silica-polymer dual layer-encapsulated quantum dots with remarkable stability. ACS Nano 4:6080–6086.
   PubMed Web of Science ®Google Scholar
• Ipe BI, Lehnig M, Niemeyer CM2005. On the generation of free radical species from quantum dots. Small 1:706–709.
   PubMed Web of Science ®Google Scholar
• Larson DR, Zipfel WR, Williams RM, Clark SW, Bruchez MP, Wise FW, 2003. Water-soluble quantum dots for multiphoton fluorescence imaging in vivo. Science 300:1434–1436.
   PubMed Web of Science ®Google Scholar
• Lin CH, Chang LW, Chang H, Yang MH, Yang CS, Lai WH, 2009. The chemical fate of the Cd/Se/Te-based quantum dot 705 in the biological system: toxicity implications. Nanotechnology 20:215101.
   PubMed Web of Science ®Google Scholar
• Lin CH, Yang MH, Chang LW, Yang CS, Chang H, Chang WH, 2010. Cd/Se/Te-based quantum dot 705 modulated redox homeostasis with hepatotoxicity in mice. Nanotoxicology; in press.
   Google Scholar
• Lin P, Chen JW, Chang LW, Wu JP, Redding L, Chang H, 2008. Computational and ultrastructural toxicology of a nanoparticle, quantum dot 705, in mice. Environ Sci Technol 42:6264–6270.
   PubMed Web of Science ®Google Scholar
• Ma N, Marshall AF, Gambhir SS, Rao J2010. Facile synthesis, silanization, and biodistribution of biocompatible quantum dots. Small 6:1520–1528.
   PubMed Web of Science ®Google Scholar
• Madl AK, Pinkerton KE2009. Health effects of inhaled engineered and incidental nanoparticles. Crit Rev Toxicol 39:629–658.
   PubMed Web of Science ®Google Scholar
• McConnachie LA, Mohar I, Hudson FN, Ware CB, Ladiges WC, Fernandez C, 2007. Glutamate cysteine ligase modifier subunit deficiency and gender as determinants of acetaminophen-induced hepatotoxicity in mice. Toxicol Sci 99:628–636.
   PubMed Web of Science ®Google Scholar
• McMillin JB, Dowhan W2002. Cardiolipin and apoptosis. Biochim Biophys Acta 1585:97–107.
   PubMed Web of Science ®Google Scholar
• Medintz IL, Uyeda HT, Goldman ER, Mattoussi H2005. Quantum dot bioconjugates for imaging, labelling and sensing. Nat Mater 4:435–446.
   PubMed Web of Science ®Google Scholar
• Michalet X, Pinaud FF, Bentolila LA, Tsay JM, Doose S, Li JJ, 2005. Quantum dots for live cells, in vivo imaging, and diagnostics. Science 307:538–544.
   PubMed Web of Science ®Google Scholar
• Motojima M, Hosokawa A, Yamato H, Muraki T, Yoshioka T2003. Uremic toxins of organic anions up-regulate PAI-1 expression by induction of NF-kappaB and free radical in proximal tubular cells. Kidney Int 63:1671–1680.
   PubMed Web of Science ®Google Scholar
• Naoi T, Shibuya N, Inoue H, Mita S, Kobayashi S, Watanabe K, 2010. The effect of tert-butylhydroquinone-induced oxidative stress in MDBK cells using XTT assay: implication of tert-butylhydroquinone-induced NADPH generating enzymes. J Vet Med Sci 72:321–326.
   PubMedGoogle Scholar
• Nel A, Xia T, Mädler L, Li N2006. Toxic potential of materials at the nanolevel. Science 311:622–627.
   PubMed Web of Science ®Google Scholar
• NRC2008. Committee on Toxicology, Committee for Review of the Federal Strategy to Address Environmental Health and Safety Research Needs for Engineered Nanoscale Material: Review of Federal Strategy for Nanotechnology-Related Environmental, Health, and Safety Research, National Academy of Sciences Press.
   Google Scholar
• Pae HO, Son Y, Kim NH, Jeong HJ, Chang KC, Chung HT2010. Role of heme oxygenase in preserving vascular bioactive NO. Nitric Oxide 23:251–257.
   PubMedGoogle Scholar
• Paine A, Eiz-Vesper B, Blasczyk R, Immenschuh S2010. Signaling to heme oxygenase-1 and its anti-inflammatory therapeutic potential. Biochem Pharmacol 80:1895–1903.
   PubMed Web of Science ®Google Scholar
• Pellegrino T, Manna L, Kudera S, Liedl T, Koktysh D, Rogach AL, 2004. Hydrophobic nanocrystals coated with an amphiphilic polymer shell a general route to water soluble nanocrystals. Nano Lett 4:703–707.
   Web of Science ®Google Scholar
• Petit JM, Maftah A, Ratinaud MH, Julien R1992. 10N-nonyl acridine orange interacts with cardiolipin and allows the quantification of this phospholipid in isolated mitochondria. Eur J Biochem 209:267–273.
   PubMedGoogle Scholar
• Poot M, Hudson FN, Grossmann A, Rabinovitch PS, Kavanagh TJ1995. Probenicid inhibition of fluorescence extrusion after MCB-staining of rat-1 fibroblasts. Cytometry 23:78–81.
   Google Scholar
• Praetner M, Rehberg M, Bihari P, Lerchenberger M, Uhl B, Holzer M, 2010. The contribution of the capillary endothelium to blood clearance and tissue deposition of anionic quantum dots in vivo. Biomaterials 31:6692–6700.
   PubMed Web of Science ®Google Scholar
• Pujalte I, Passagne I, Brouillaud B, Treguer M, Durand E, Ohayon-Courtes C, 2011. Cytotoxicity and oxidative stress induced by different metallic nanoparticles on human kidney cells. Part Fibre Toxicol 8:10.
   PubMed Web of Science ®Google Scholar
• Qi L, Gao X2008. Quantum dot-amphipol nanocomplex for intracellular delivery and real-time imaging of siRNA. ACS Nano 2:1403–1410.
   PubMed Web of Science ®Google Scholar
• Rikans LE, Yamano T2000. Mechanisms of cadmium-mediated acute hepatotoxicity. J Biochem Mol Toxicol 14:110–117.
   PubMed Web of Science ®Google Scholar
• Robe A, Pic E, Lassalle HP, Bezdetnaya L, Guillemin F, Marchal F2008. Quantum dots in axillary lymph node mapping: biodistribution study in healthy mice. BMC Cancer 8:111.
   PubMed Web of Science ®Google Scholar
• Rosenthal SJ, Chang JC, Kovtun O, McBride JR, Tomlinson ID2011. Biocompatible quantum dots for biological applications. Chem Biol 18:10–24.
   PubMed Web of Science ®Google Scholar
• Shaw SY, Westly EC, Pittet MJ, Subramanian A, Schreiber SL, Weissleder R2008. Perturbational profiling of nanomaterial biologic activity. Proc Natl Acad Sci USA 105:7387–7392.
   PubMed Web of Science ®Google Scholar
• Stern ST, Zolnik BS, McLeland CB, Clogston J, Zheng J, McNeil SE2008. Induction of autophagy in porcine kidney cells by quantum dots: a common cellular response to nanomaterials? Toxicol Sci 106:140–152.
   PubMed Web of Science ®Google Scholar
• Vibin M, Vinayakan R, John A, Raji V, Rejiya CS, Abraham A2011. Biokinetics and in vivo distribution behaviours of silica-coated cadmium selenide quantum dots. Biol Trace Elem Res 142:213–222.
   PubMedGoogle Scholar
• Wright MM, Howe AG, Zaremberg V2004. Cell membranes and apoptosis: role of cardiolipin, phosphatidylcholine, and anticancer lipid analogues. Biochem Cell Biol 82:18–26.
   PubMedGoogle Scholar
• Xia T, Li N, Nel AE2009. Potential health impact of nanoparticles. Annu Rev Public Health 30:137–150.
   PubMed Web of Science ®Google Scholar
• Yang L, Mao H, Wang YA, Cao Z, Peng X, Wang X, 2009. Single chain epidermal growth factor receptor antibody conjugated nanoparticles for in vivo tumor targeting and imaging. Small 5:235–243.
   PubMed Web of Science ®Google Scholar
• Yang RS, Chang LW, Wu JP, Tsai MH, Wang HJ, Kuo YC, 2007. Persistent tissue kinetics and redistribution of nanoparticles, quantum dot 705, in mice: ICP-MS quantitative assessment. Environ Health Perspect 115:1339–1343.
   PubMed Web of Science ®Google Scholar
• Yeh TK, Wu JP, Chang LW, Tsai MH, Chang WH. 2011. Comparative tissue distributions of cadmium chloride and cadmium-based quantum dot 705 in mice: Safety implications and applications. Nanotoxicology 5:91–97.
   PubMed Web of Science ®Google Scholar
• Yong KT, Roy I, Ding H, Bergey EJ, Prasad PN2009. Biocompatible near-infrared quantum dots as ultrasensitive probes for long-term in vivo imaging applications. Small 5:1997–2004.
   PubMed Web of Science ®Google Scholar
• Zrazhevskiy P, Gao X2009. Multifunctional quantum dots for personalized medicine. Nano Today 4:414–428.
   PubMed Web of Science ®Google Scholar