Primary human hepatocytes versus hepatic cell line: assessing their suitability for in vitro nanotoxicology

References

• Anreddy RNR, Devarakonda RK, Vurimindi H, Yellu NR. 2011. In vitro cytotoxicity of carbon nanoparticles against HepG32 cells. Latin Am J Pharm 30:177–180.
   Web of Science ®Google Scholar
• Buzea C, Pacheco II, Robbie K. 2007. Nanomaterials and nanoparticles: Sources and toxicity. Biointerpahses 2:18–67.
   Web of Science ®Google Scholar
• Chen C, Zhang P, Hou X, Chai Z. 1999. Sub-cellular distribution of selenium and Se-containing proteins in human liver. Biochem Biophys Acta 1427:205–215.
   PubMed Web of Science ®Google Scholar
• Delpino MV, Barrionuevo P, Scian R, Fossati CA, Balsi PC. 2010. Brucella-infected heaptocytes mediate potentially tissue-damaging immune responses. J Hepatol 53:145–154.
   PubMed Web of Science ®Google Scholar
• Dong WM, Simeonova PP, Gallucci R, Matheson J, Flood L, Wang SY, et al. 1998. Toxic metals stimulate inflammatory cytokines in hepatocytes through oxidative stress mechanisms. Toxicol Appl Pharmacol 151:359–366.
   PubMed Web of Science ®Google Scholar
• Guengerich FP. 2001. Common and uncommon cytochrome P450 reactions related to metabolism and chemical toxicity. Chem Res Toxicol 14:611–650.
   PubMed Web of Science ®Google Scholar
• Hansson PK, Asztely AK, Clapham JC, Schreyer SA. 2004. Glucose and fatty acid metabolism in McA-RH7777 hepatoma cells vs. rat primary hepatocytes: responsiveness to nutrient availability. Biochem Biophys Acta 1684:54–62.
   PubMed Web of Science ®Google Scholar
• Hoet PHM, Hohlfeld IB, Salata O. 2004. Nanoparticles – known and unknown health risks. J Nanobiotechnology 2:12–27.
   PubMedGoogle Scholar
• Jacobsen NR, Pojano G, Wallin H, Jensen KA. 2010. Nanomaterial dispersion protocol for toxicological studies in ENPRA. Internal ENPRA Project Report. The National Research Centre for the Working Environment. pp 6.
   Google Scholar
• Jin CY, Zhu BS, Wang XF, Lu QH. 2008. Cytotoxicity of titanium dioxide nanoparticles in mouse fibroblast cells. Chem Res Toxicol 21:1871–1877.
   PubMed Web of Science ®Google Scholar
• Kermanizadeh A, Pojana G, Gaiser BK, Birkedal R, Bilaničová D, Wallin H, et al. 2012. In vitro assessment of engineered nanomaterials using C3A cells: cytotoxicity, pro-inflammatory cytokines and function markers. Nanotoxicology; ahead of print.
   Web of Science ®Google Scholar
• Kim BS, Park IK, Hoshiba T, Jiang HL, Choi YJ, Akaike Y, et al. 2011. Design of artificial extracellular matrices for tissue engineering. Prog Polym Sci 36:238–268.
   Web of Science ®Google Scholar
• Kmiec Z. 2001. Co-operation of liver cells in health and disease. Advances in Anatomy. Embryol Cell Biol 161:1–151.
   PubMedGoogle Scholar
• Liguori MJ, Blomme EAG, Waring JF. 2008. Trovafloxacin induced gene expression changes in liver derived in vitro systems: comparison of primary human hepatocytes to HepG2 cells. Drug Metab Dispos 36:223–233.
   PubMed Web of Science ®Google Scholar
• Liu C, Tsai AL, Chen YC, Fan SH, Huang CH, Wu CC, et al. 2012. Facilitation of human osteoblast apoptosis by sulindac and indomethacin under hypoxic injury. J Cell Biochem 113:148–155.
   PubMed Web of Science ®Google Scholar
• Maynard AD, Aitkin RJ, Butz T, Colvin V, Donaldson K, Oberdorster G, et al. 2006. Safe handling of nanotechnology. Nature 444:267–269.
   PubMed Web of Science ®Google Scholar
• Mingoia RT, Nabb DL, Yang CH, Han X. 2007. Primary culture of rat hepatocytes in 96 well plates: Effects of extracellular matrix configuration on cytochrome P450 enzyme activity and inducibility and its application in vitro cytotoxicity screening. Toxicol In Vitro 21:165–173.
   PubMed Web of Science ®Google Scholar
• Oberdorster G, Maynard A, Donaldson K, Castranova V, Fitzpatrick J, Ausman K, et al. 2005. Principles for characterizing the potential human health effects from exposure to nanomaterials: elements of a screening strategy. Part Fibre Toxicol 42:1–35.
   Google Scholar
• Piao MJ, Kang KA, Lee IK, Kim HS, Kim S, Choi JY, et al. 2011. Silver nanoparticles induce oxidative cell damage in human liver cells through inhibition of reduced glutathione and induction of mitochondrial involved apoptosis. Toxicol Lett 201:92–100.
   PubMed Web of Science ®Google Scholar
• Pichardo S, Gutierrez-Praena D, Puerto M, Sanchez E, Grilo A, Camean AM, et al. 2012. Oxidative stress responses to carboxylic acid functionalized single wall carbon nanotubes on the human intestinal cell line Caco-2. Toxicol In Vitro; ahead of print.
   PubMed Web of Science ®Google Scholar
• Raffa V, Gherardini L, Vittorio O, Bardi G, Ziaei A, Pizzorusso T, et al. 2011. Carbon nanotube-mediated wireless cell permeabilization: drug and gene uptake. Nanomedicine 6:1709–1718.
   PubMed Web of Science ®Google Scholar
• Rothen-Rutishauser BM, Schurch S, Haenni B, Kapp N, Gehr R. 2006. Interaction of fine particles and nanoparticles with red blood cells visualised with advanced microscopic techniques. Environ Sci Technol 40:4353–4359.
   PubMed Web of Science ®Google Scholar
• Saad B, Frei K, Scholl FA, Fontana A, Maier P. 1995. Hepatocyte-derived interleukin-6 and tumour-necrosis factor alpha mediate the lipopolysaccharide-induced acute-phase response and nitric oxide release by cultured rat hepatocytes. Eur J Chem 229:349–355.
   Web of Science ®Google Scholar
• Sadauskas E, Jacobson NR, Danscher G, Soltenberg M, Larsen A, Kreyling W, et al. 2009. Bio-disruption of gold nanoparticles in mouse lung following intratracheal instillation. Chem Central J 3:16–23.
   PubMed Web of Science ®Google Scholar
• Sahi J, Grepper S, Smith C. 2010. Hepatocytes as a tool in drug metabolism, transport and safety evaluations in drug discovery. Curr Drug Discov Technol 7:188–198.
   PubMedGoogle Scholar
• Semmler-Behnke M, Wolfgang KG, Lipka J, Fertsch S, Wenk A, Takeneka S, et al. 2008. Bio-distribution of 1.4 and 18 nm gold particles in rats. Small 12:2108–2111.
   Web of Science ®Google Scholar
• Sharma V, Anderson D, Dhawan A. 2011. Zinc oxide nanoparticles induce oxidative stress and genotoxicity in human liver cells (HepG2). J Biomed Nanotechnol 7:98–99.
   PubMed Web of Science ®Google Scholar
• Shvedova AA, Pietroiusti A, Fadeel B, Kagan VE. 2012. Mechanism of carbon nanotube-induced toxicity: Focus on oxidative stress. Toxicol Appl Pharmacol; ahead of press.
   PubMed Web of Science ®Google Scholar
• Tetley TD. 2007. Health effects of nanomaterials. Bionanotechnology 35:527–531.
   Google Scholar
• Villeneuve JP, Pichette V. 2004. Cytochrome P450 and the liver diseases. Curr Drug Metab 5:273–282.
   PubMed Web of Science ®Google Scholar
• Wang YG, Aker WG, Hwang HM, Yedjou CG, Yu HT, Tchounwou PB. 2011. A study of the mechanism of in vitro cytotoxicity of metal oxide nanoparticles using catfish primary heaptocytes and human HepG2 cells. Sci Total Environ 409:4753–4762.
   PubMed Web of Science ®Google Scholar
• Wanninger J, Neumeier M, Weigert J, Bauer S, Weiss TS, Schaffler A, et al. 2009. Adiponectin stimulated CXCL8 release in primary human hepatocytes is regulated by ERK1/ERK2, p38 MAPK, NF kappa B and STAT 3 signalling pathways. Am J Physiol Gastrointestin Liver Physiol 297:611–618.
   PubMed Web of Science ®Google Scholar
• Westerink WMA, Schoonen WGEJ. 2007. Cytochrome P450 enzyme levels in HepG2 cells and cryopreserved primary human hepatocytes and their induction in HepG2 cells. Toxicol In Vitro 21:1581–1591.
   PubMed Web of Science ®Google Scholar
• Woodrow Wilson. Available online at http://www.nanotechproject.org/inventories/consumer/browse/products/. Accessed 16-1-2012.
   Google Scholar
• Wongkajornslip A, Sa-Ngiamsuntorn K, Hongeng S. 2012. Development of immortalized Hepatocyte-like cells from hMSCs. Methods Mol Biol 826:73–87.
   PubMedGoogle Scholar