Identification of the appropriate dose metric for pulmonary inflammation of silver nanoparticles in an inhalation toxicity study

References

• Anjilvel S, Asgharian B. 1995. A multiple-path model of particle deposition in the rat lung. Fundam Appl Toxicol 28:41–50
   PubMedGoogle Scholar
• Asgharian B, Price O, Miller F, Subramaniam R, Cassee FR, Freijer J, et al. 2009. Multiple-path particle dosimetry model (MPPD v 2.11): a model for human and rat airway particle dosimetry. In: Applied Research Associates (ARA), H. I. F. H. S., National Institute for Public Health and the Environment (RIVM), and Ministry of Housing, Spatial Planning and the Environment (ed.) V2.11 ed. Raleigh, North Carolina, USA: Applied Research Associates (ARA)
   Google Scholar
• Baisch BL, Corson NM, Wade-Mercer P, Gelein R, Kennell AJ, Oberdorster G, Elder A. 2014. Equivalent titanium dioxide nanoparticle deposition by intratracheal instillation and whole body inhalation: the effect of dose rate on acute respiratory tract inflammation. Part Fibre Toxicol 11:5–20
   PubMed Web of Science ®Google Scholar
• Bakand S, Hayes A, Dechsakulthorn F. 2012. Nanoparticles: a review of particle toxicology following inhalation exposure. Inhal Toxicol 24:125–35
   PubMed Web of Science ®Google Scholar
• Barlow S, Chesson A, Collins JD, Flynn A, Hardy A, Jany K, et al. 2009. Use of the benchmark dose approach in risk assessment. EFSA J 1150:1–72
   Google Scholar
• Beer C, Foldbjerg R, Hayashi Y, Sutherland DS, Autrup H. 2012. Toxicity of silver nanoparticles – nanoparticle or silver ion? Toxicol Lett 208:286–92
   PubMed Web of Science ®Google Scholar
• Braakhuis HM, Gosens I, Krystek P, Boere J, Cassee FR, Fokkens P, et al. 2014a. Particle size dependent deposition and pulmonary inflammation after short-term inhalation of silver nanoparticles. Part Fibre Toxicol 11:49
   PubMed Web of Science ®Google Scholar
• Braakhuis HM, Park MV, Gosens I, de Jong WH, Cassee FR. 2014b. Physicochemical characteristics of nanomaterials that affect pulmonary inflammation. Part Fibre Toxicol 11:18–42
   PubMed Web of Science ®Google Scholar
• Cassee FR, Muijser H, Duistermaat E, Freijer JJ, Geerse KB, Marijnissen JC, Arts JH. 2002. Particle size-dependent total mass deposition in lungs determines inhalation toxicity of cadmium chloride aerosols in rats. Application of a multiple path dosimetry model. Arch Toxicol 76:277–86
   PubMed Web of Science ®Google Scholar
• Cho WS, Duffin R, Thielbeer F, Bradley M, Megson IL, Macnee W, et al. 2012. Zeta potential and solubility to toxic ions as mechanisms of lung inflammation caused by metal/metal oxide nanoparticles. Toxicol Sci 126:469–77
   PubMed Web of Science ®Google Scholar
• Du YK, Yang P, Mou ZG, Hua NP, Jiang L. 2006. Thermal decomposition behaviors of PVP coated on platinum nanoparticles. J Appl Polym Sci 99:23–6
   Web of Science ®Google Scholar
• Duffin R, Tran L, Brown D, Stone V, Donaldson K. 2007. Proinflammogenic effects of low-toxicity and metal nanoparticles in vivo and in vitro: highlighting the role of particle surface area and surface reactivity. Inhal Toxicol 19:849–56
   PubMed Web of Science ®Google Scholar
• EFSA. 2009. Guidance of the Scientific Committe on a request from EFSA on the use of the benchmark dose approach in risk assessment. EFSA J 1150:1–72
   Google Scholar
• Franek J. 2001. Temperature Dependence of Silver Oxide Formation. Minnesota: University of Minnesota
   Google Scholar
• Geiser M, Casaulta M, Kupferschmid B, Schulz H, Semmler-Behnke M, Kreyling W. 2008. The role of macrophages in the clearance of inhaled ultrafine titanium dioxide particles. Am J Respir Cell Mol Biol 38:371–6
   PubMed Web of Science ®Google Scholar
• Geiser M, Kreyling WG. 2010. Deposition and biokinetics of inhaled nanoparticles. Part Fibre Toxicol 7:2–18
   PubMed Web of Science ®Google Scholar
• Gerlofs-Nijland ME, Dormans JA, Bloemen HJ, Leseman DL, Boere JAF. 2007. Toxicity of coarse and fine particulate matter from sites with contrasting traffic profiles. Inhal Toxicol 19:1055–69
   PubMed Web of Science ®Google Scholar
• Gosens I, Mathijssen LE, Bokkers BG, Muijser H, Cassee FR. 2014. Comparative hazard identification of nano- and micro-sized cerium oxide particles based on 28-day inhalation studies in rats. Nanotoxicology 8:643–53
   PubMed Web of Science ®Google Scholar
• Ho M, Wu KY, Chein HM, Chen LC, Cheng TJ. 2011. Pulmonary toxicity of inhaled nanoscale and fine zinc oxide particles: mass and surface area as an exposure metric. Inhal Toxicol 23:947–56
   PubMed Web of Science ®Google Scholar
• Horie M, Fukui H, Endoh S, Maru J, Miyauchi A, Shichiri M, et al. 2012. Comparison of acute oxidative stress on rat lung induced by nano and fine-scale, soluble and insoluble metal oxide particles: NiO and TiO2. Inhal Toxicol 24:391–400
   PubMed Web of Science ®Google Scholar
• Kent RD, Vikesland PJ. 2012. Controlled evaluation of silver nanoparticle dissolution using atomic force microscopy. Environ Sci Technol 46:6977–84
   PubMed Web of Science ®Google Scholar
• Kobayashi N, Naya M, Endoh S, Maru J, Yamamoto K, Nakanishi J. 2009. Comparative pulmonary toxicity study of nano-TiO2 particles of different sizes and agglomerations in rats: different short- and long-term post-instillation results. Toxicology 264:110–18
   PubMed Web of Science ®Google Scholar
• Krystek P. 2012. A review on approaches to biodistribution studies about gold and silver engineered nanoparticles by inductively couples plasma mass spectrometry. Microchem J 105:39–43
   Web of Science ®Google Scholar
• Krystek P, Braakhuis HM, Park MVDZ, Jong WHD. 2013. Inductively Coupled Plasma-mass Spectrometry in biodistribution Studies of (engineered) Nanoparticles. Encyclopedia of Analytical Chemistry. Hoboken, NJ: John Wiley & Sons, Ltd
   Google Scholar
• Landsiedel R, Ma-Hock L, Kroll A, Hahn D, Schnekenburger J, Wiench K, Wohlleben W. 2010. Testing metal-oxide nanomaterials for human safety. Adv Mater 22:2601–27
   PubMed Web of Science ®Google Scholar
• Leo BF, Chen S, Kyo Y, Herpoldt KL, Terrill NJ, Dunlop IE, et al. 2013. The stability of silver nanoparticles in a model of pulmonary surfactant. Environ Sci Technol 47:11232–40
   PubMed Web of Science ®Google Scholar
• Lubick N. 2008. Nanosilver toxicity: ions, nanoparticles – or both? Environ Sci Technol 42:8617
   PubMed Web of Science ®Google Scholar
• Ma-Hock L, Strauss V, Treumann S, Kuttler K, Wohlleben W, Hofmann T, et al. 2013. Comparative inhalation toxicity of multi-wall carbon nanotubes, graphene, graphite nanoplatelets and low surface carbon black. Part Fibre Toxicol 10:23–42
   PubMed Web of Science ®Google Scholar
• Ma R, Levard C, Marinakos SM, Cheng Y, Liu J, Michel FM, et al. 2012. Size-controlled dissolution of organic-coated silver nanoparticles. Environ Sci Technol 46:752–9
   PubMed Web of Science ®Google Scholar
• Muhlfeld C, Gehr P, Rothen-Rutishauser B. 2008. Translocation and cellular entering mechanisms of nanoparticles in the respiratory tract. Swiss Med Wkly 138:387–91
   PubMed Web of Science ®Google Scholar
• Nanotechnologies POE. 2014. Consumer products inventory. [Online] Available at: http://www.nanotechproject.org/cpi. Accessed on June 2014
   Google Scholar
• Oberdorster G, Finkelstein JN, Johnston C, Gelein R, Cox C, Baggs R, Elder AC. 2000. Acute pulmonary effects of ultrafine particles in rats and mice. Res Rep Health Eff Inst 96:5–74; disc 75–86
   PubMedGoogle Scholar
• Oberdorster G, Pott F. 1987. Extrapolation from rat studies with environmental tobacco smoke (ETS) to humans: comparison of particle mass deposition and of clearance behavior of ETS compounds. Toxicol Lett 35:107–12
   PubMed Web of Science ®Google Scholar
• Park EJ, Yi J, Kim Y, Choi K, Park K. 2010. Silver nanoparticles induce cytotoxicity by a Trojan-horse type mechanism. Toxicol In Vitro 24:872–8
   PubMed Web of Science ®Google Scholar
• Park MV, Annema W, Salvati A, Lesniak A, Elsaesser A, Barnes C, et al. 2009. In vitro developmental toxicity test detects inhibition of stem cell differentiation by silica nanoparticles. Toxicol Appl Pharmacol 240:108–16
   PubMed Web of Science ®Google Scholar
• Pauluhn J. 2009. Pulmonary toxicity and fate of agglomerated 10 and 40 nm aluminum oxyhydroxides following 4-week inhalation exposure of rats: toxic effects are determined by agglomerated, not primary particle size. Toxicol Sci 109:152–67
   PubMed Web of Science ®Google Scholar
• Peniche C, Zaldivar D, Pazos M, Paz S, Bulay A, San Roman J. 1993. Study of the thermal degradation of poly(N-vinyl-2-pyrrolidone) by thermogravimetry-FTIR. J Appl Polym Sci 50:485–93
   Web of Science ®Google Scholar
• Phalen RF, Mendez LB, Oldham MJ. 2010. New developments in aerosol dosimetry. Inhal Toxicol 22:6–14
   PubMed Web of Science ®Google Scholar
• Pratsinis A, Hervella P, Leroux JC, Pratsinis SE, Sotiriou GA. 2013. Toxicity of silver nanoparticles in macrophages. Small 9:2576–84
   PubMed Web of Science ®Google Scholar
• RIVM. 2014. PROAST: software for dose–response modeling and benchmark dose analysis. PROAST38. 9 edn. Bilthoven, The Netherlands.
   Google Scholar
• Roursgaard M, Poulsen SS, Poulsen LK, Hammer M, Jensen KA, Utsunomiya S, et al. 2010. Time–response relationship of nano and micro particle induced lung inflammation. Quartz as reference compound. Hum Exp Toxicol 29:915–33
   PubMed Web of Science ®Google Scholar
• SCENIHR. 2010. Basis for the definition of the term ‘nanomaterial'. Brussels, Belgium: European Commission
   Google Scholar
• Schinwald A, Murphy FA, Jones A, Macnee W, Donaldson K. 2012. Graphene-based nanoplatelets: a new risk to the respiratory system as a consequence of their unusual aerodynamic properties. ACS Nano 6:736–46
   PubMed Web of Science ®Google Scholar
• Slob W. 2002. Dose–response modeling of continuous endpoints. Toxicol Sci 66:298–312
   PubMed Web of Science ®Google Scholar
• Slob W. 2014a. Benchmark dose and the three Rs. Part I. Getting more information from the same number of animals. Crit Rev Toxicol 44:557–67
   PubMed Web of Science ®Google Scholar
• Slob W. 2014b. Benchmark dose and the three Rs. Part II. Consequences for study design and animal use. Crit Rev Toxicol 44:568–80
   PubMed Web of Science ®Google Scholar
• Stebounova LV, Guio E, Grassian VH. 2011. Silver nanoparticles in simulated biological media: a study of aggregation, sedimentation, and dissolution. J Nanopar Res 13:233–44
   Web of Science ®Google Scholar
• Stoeger T, Reinhard C, Takenaka S, Schroeppel A, Karg E, Ritter B, et al. 2006. Instillation of six different ultrafine carbon particles indicates a surface area threshold dose for acute lung inflammation in mice. Environ Health Perspect 114:328–33
   PubMed Web of Science ®Google Scholar
• van Ravenzwaay B, Landsiedel R, Fabian E, Burkhardt S, Strauss V, Ma-Hock L. 2009. Comparing fate and effects of three particles of different surface properties: nano-TiO(2), pigmentary TiO(2) and quartz. Toxicol Lett 186:152–9
   PubMed Web of Science ®Google Scholar
• Wang X, Ji Z, Chang CH, Zhang H, Wang M, Liao YP, et al. 2014. Use of coated silver nanoparticles to understand the relationship of particle dissolution and bioavailability to cell and lung toxicological potential. Small 10:385–98
   PubMed Web of Science ®Google Scholar
• Warheit DB, Webb TR, Colvin VL, Reed KL, Sayes CM. 2007a. Pulmonary bioassay studies with nanoscale and fine-quartz particles in rats: toxicity is not dependent upon particle size but on surface characteristics. Toxicol Sci 95:270–80
   PubMed Web of Science ®Google Scholar
• Warheit DB, Webb TR, Reed KL, Frerichs S, Sayes CM. 2007b. Pulmonary toxicity study in rats with three forms of ultrafine-TiO2 particles: differential responses related to surface properties. Toxicology 230:90–104
   PubMed Web of Science ®Google Scholar
• Warheit DB, Webb TR, Sayes CM, Colvin VL, Reed KL. 2006. Pulmonary instillation studies with nanoscale TiO2 rods and dots in rats: toxicity is not dependent upon particle size and surface area. Toxicol Sci 91:227–36
   PubMed Web of Science ®Google Scholar
• Wijnhoven SWP, Peijnenburg WJGM, Herberts CA, Hagens WI, Oomen AG, Heugens EHW, et al. 2009. Nano-silver – a review of available data and knowledge gaps in human and environmental risk assessment. Nanotoxicology 3:109–44
   Web of Science ®Google Scholar
• Yeh HC, Schum GM, Duggan MT. 1979. Anatomic models of the tracheobronchial and pulmonary regions of the rat. Anat Rec 195:483–92
   PubMedGoogle Scholar
• Zhu MT, Feng WY, Wang B, Wang TC, Gu YQ, Wang M, et al. 2008. Comparative study of pulmonary responses to nano- and submicron-sized ferric oxide in rats. Toxicology 247:102–11
   PubMed Web of Science ®Google Scholar
• Zook JM, Long SE, Cleveland D, Geronimo CL, Maccuspie RI. 2011. Measuring silver nanoparticle dissolution in complex biological and environmental matrices using UV–visible absorbance. Anal Bioanal Chem 401:1993–2002
   PubMed Web of Science ®Google Scholar