Copper oxide nanoparticles aggravate airway inflammation and mucus production in asthmatic mice via MAPK signaling

References

• Acciani TH, Brandit EB, Khurana Hershey GK, Le Cras TD. 2013. Diesel exhaust particle exposure increases severity of allergic asthma in young mice. Clin Exp Allergy 43:1406–18
   PubMed Web of Science ®Google Scholar
• Alam R, Gorska MM. 2011. Mitogen-activated protein kinase signaling and ERK1/2 bistability in asthma. Clin Exp Allergy 41:149–59
   PubMed Web of Science ®Google Scholar
• Atherton HC, Jones G, Danahay H. 2003. IL-13-induced changes in the goblet cell density of human bronchial epithelial cell cultures: MAP kinase and phosphatidylinositol 3-kinase regulation. Am J Physiol Lung Cell Mol Physiol 285:L730–9
   PubMed Web of Science ®Google Scholar
• Busse PJ, Zhang TF, Srivastava K, Lin BP, Schofield B, Sealfon SC, et al. 2005. Chronic exposure to TNF-alpha increases airway mucus gene expression in vivo. J Allergy Clin Immunol 116:1256–63
   PubMed Web of Science ®Google Scholar
• Casalino-Matsuda SM, Monzon ME, Forteza RM. 2006. Epithermal growth factor receptor activation by epithermal growth factor mediates oxidant-induced goblet cell metaplasia in human airway epithelium. Am J Respir Cell Mol Biol 34:581–91
   PubMed Web of Science ®Google Scholar
• Cho WS, Duffin R, Poland CA, Duschl A, Oostingh GJ, Macnee W, et al. 2012. Differential pro-inflammatory effects of metal oxide nanoparticles and their soluble ions in vitro and in vivo; zinc and copper nanoparticles, but not their ions, recruit eosinophils to the lung. Nanotoxicology 6:22–35
   PubMed Web of Science ®Google Scholar
• Elsaesser A, Howard CV. 2012. Toxicology of nanoparticles. Adv Drug Deliv Rev 64:129–37
   PubMed Web of Science ®Google Scholar
• Grommes J, Soehnlein O. 2011. Contribution of neutrophils to acute lung injury. Mol Med 17:293–307
   PubMed Web of Science ®Google Scholar
• Hansbro PM, Kaiko GE, Foster PS. 2011. Cytokine/anticytokines therapy – novel treatments for asthma. Brit J Pharmacol 163:81–95
   PubMed Web of Science ®Google Scholar
• Heussen C, Dowdel EB. 1980. Electrophoretic analysis of plasminogen activators in polyacrylamide gels containing sodium dodecyl sulfate and copolymerized substrate. Anal Biochem 102:196–202
   PubMed Web of Science ®Google Scholar
• Hewson CA, Edbrooke MR, Johnston SL. 2004. PMA induces the MUC5AC respiratory mucin in human bronchial epithelial cells, via PKC, EGF/TGF-alpha, Ras/Raf, MEK, ERK and Sp1-dependent mechanism. J Mol Biol 344:683–95
   PubMed Web of Science ®Google Scholar
• Holgate ST. 2008. The airway epithelium is central to the pathogenesis of asthma. Allergol Int 57:1–10
   PubMedGoogle Scholar
• Hsin YH, Chena CF, Huang S, Shih TS, Lai PS, Cheuh PJ. 2008. The apoptotic effect of nanosilver is mediated by a ROS and JNK-dependent mechanism involving the mitochondrial pathway in NIH3T3 cells. Toxicol Lett 179:130–9
   PubMed Web of Science ®Google Scholar
• Hu W, Culloty S, Darmody G, Lynch S, Davenport J, Ramirez-Garcia S, et al. 2014. Toxicity of copper oxide nanoparticles in the blue mussel, Mytilus edulis: a redox proteomic investigation. Chemosphere 108:289–99
   PubMed Web of Science ®Google Scholar
• Kahru A, Ivask A. 2013. Mapping the dawn of nanoecotoxicological research. Acc Chem Res 46:823–33
   PubMed Web of Science ®Google Scholar
• Kim SR, Lee KS, Park SJ, Jeon MS, Lee YC. 2012. Inhibition of p38 MAPK reduce expression of vascular endothelial growth factor in allergic airway disease. J Clin Immunol 32:574–86
   PubMed Web of Science ®Google Scholar
• Kumar R, Nagesha DK. 2013. Size-dependent study of pulmonary responses to nano-sized iron and copper oxide nanoparticles. Methods Mol Biol 1028:247–64
   PubMedGoogle Scholar
• Lee GB, Brandt EB, Xiao C, Gibson AM, Le Cras TD, Brown LA, et al. 2013. Diesel exhaust particles induce cysteine oxidation and s-glutathionylation in house dust mite induced murine asthma. PLoS One 8:e60632
   PubMed Web of Science ®Google Scholar
• Lee MY, Seo CS, Lee JA, Lee NH, Kim JH, Ha H, et al. 2011. Anti-asthmatic effects of angelica dahurica against ovalbumin-induced airway inflammation via upregulation of heme oxygenase-1. Food Chem Toxicol 49:829–37
   PubMed Web of Science ®Google Scholar
• Liu W, Liang Q, Balzar S, Wenzel S, Gorska M, Alam R. 2008. Cell-specific activation profile of extracellular signal-regulated kinase 1/2, Jun N-terminal kinase, and p38 mitogen-activated protein kinases in asthmatic airways. J Allergy Clin Immunol 121:893–902
   PubMed Web of Science ®Google Scholar
• Mortimer M, Kasemets K, Kahru A. 2010. Toxicity of ZnO and CuO nanoparticles to ciliated protozoa Tetrahymena thermophila. Toxicology 269:182–9
   PubMed Web of Science ®Google Scholar
• Mwaanga P, Carraway ER, van den Hurk P. 2014. The induction of biochemical changes in Daphnia magna by CuO and ZnO nanoparticles. Aquat Toxicol 150:201–9
   PubMed Web of Science ®Google Scholar
• Nowack B, Ranville JF, Diamond S, Gallego-Urrea JA, Metcalfe C, Rose J, et al. 2012. Potential scenarios for nanomaterial release and subsequent alteration in the environment. Environ Toxicol Chem 31:50–9
   PubMed Web of Science ®Google Scholar
• Pelaia G, Cuda G, Vatrella A, Gallelli L, Caraglia M, Marra M, et al. 2005. Mitogen-activated protein kinases and asthma. J Cell Physiol 202:642–53
   PubMed Web of Science ®Google Scholar
• Piret JP, Jacques D, Audinot JN, Mejia J, Boilan E, Noel F, et al. 2012. Copper(II) oxide nanoparticles penetrate into HepG2 cells, exert cytotoxicity via oxidative stress and induce pro-inflammatory response. Nanoscale 4:7168–84
   PubMed Web of Science ®Google Scholar
• Possa SS, Leick EA, Prado CM, Martins MA, Tiberio IF. 2013. Eosinophilic inflammation in allergic asthma. Front Pharmacol 4:46
   PubMed Web of Science ®Google Scholar
• Profita M, Sala A, Bonanno A, Riccobono L, Ferraro M, La Grutta S, et al. 2010. Chronic obstructive pulmonary disease and neutrophil infiltration: role of cigarette smoke and cyclooxygenase products. Am J Physiol Lung Cell Mol Physiol 298:L262–9
   Web of Science ®Google Scholar
• Sava F, MacNutt MJ, Carlsten CR. 2013. Nasal neurogenic inflammation markers increase after diesel exhaust inhalation in individuals with asthma. Am J Respir Crit Care Med 188:759–60
   PubMed Web of Science ®Google Scholar
• Shao MX, Nakanaga T, Nadel JA. 2004. Cigarette smoke induces MUC5AC mucin overproduction via tumor necrosis factor-alpha-converting enzyme in human airway epithelial (NCI-H292) cells. Am J Physiol Lung Cell Mol Physiol 287:L420–7
   PubMed Web of Science ®Google Scholar
• Shin IS, Park JW, Shin NR, Jeon CM, Kwon OK, Kim JS, et al. 2014. Melatonin reduces airway inflammation in ovalbumin-induced asthma. Immunobiology 219:901–8
   PubMed Web of Science ®Google Scholar
• Singh D, Kane B, Molfino NA, Faggioni R, Roskos L, Woodcock A. 2010. A phase 1 study evaluating the pharmacokinetics, safety and tolerability of repeat dosing with a human IL-13 antibody (CAT-354) in subjects with asthma. BMC Pulm Med 10:3
   PubMed Web of Science ®Google Scholar
• Tachdjian R, Mathias C, Al Khatib S, Bryce PJ, Kim HS, Blaeser F, et al. 2009. Pathogenicity of a disease-associated human IL-4 receptor allele in experimental asthma. J Exp Med 206:2191–204
   PubMed Web of Science ®Google Scholar
• Tiede K, Hasselly M, Breitbarth E, Chaudhry Q, Boxall ABA. 2009. Considerations for environmental fate and ecotoxicity testing to support environmental risk assessments for engineered nanoparticles. J Chromatogr Part A 1216:503–9
   PubMed Web of Science ®Google Scholar
• Welte T, Groneberg DA. 2006. Asthma and COPD. Exp Toxicol Pathol 2:35–40
   Web of Science ®Google Scholar
• Winterbourn C. 2008. Reconciling the chemistry and biology of reactive oxyten species. Nat Chem Biol 4:278–86
   PubMed Web of Science ®Google Scholar