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RESEARCH COMMUNICATION

Citrus limon extract: possible inhibitory mechanisms affecting testicular functions and fertility in male mice

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Pages 39-48 | Received 22 Feb 2015, Accepted 01 Jun 2015, Published online: 02 Oct 2015

References

  • Abercrombie, M. (1946) Estimation of nuclear population from microtome sections. Anat Rec 94:239–247
  • Campelo, L.M.L., de Almeida, A.A.C., de Freitas, R.L.M., Cerqueira, G.S., de Sousa, G.F., Saldanha, G.B., et al. (2011) Antioxidant and antinociceptive effects of Citrus limon essential oil in mice. J Biomed Biotechnol 2011:678673. doi:10.1155/2011/678673
  • Dym, M. and Fawcett, D.W. (1971) Further observations on the number of spermatogonia, spermatocytes, and spermatids connected by intercellular bridges in the mammalian testis. Bio Reprod 4:195–215
  • D’Souza, U.J.A. (2004) Effect of tamoxifen on spermatogenesis and tubular morphology in rats. Asian J Androl 6:223–226
  • Faridha, A., Faisal, K. and Akbarsha, M.A. (2007) Aflatoxin treatment brings about generation of multinucleate giant spermatids (symplasts) through opening of cytoplasmic bridges: Light and transmission electron microscopic study in Swiss mouse. Reproductive Toxicology 24:403–408
  • Hammami, I., Amara, S., Benahmed, M., El May, M.V. and Mauduit, C. (2009) Chronic crude garlic-feeding modified adult male rat testicular markers: mechanisms of action. Reprod Biol Endocrinol 7:65. DOI: 10.1186/1477-7827-7-65
  • Jarabak, J., Adams, J.A., Williams-Ashaman, H.G. and Talalay, P. (1962) Purification of a 17β hydroxysteroid dehydrogenase of human placenta and studies on its transhydrogenase function. J Biol Chem 237:345–357
  • Johann, S., de Oliveira, V.L., Pizzolatti, M.G., Schripsema, J., Braz-Filho, R., Branco, A., et al. (2007) Antimicrobial activity of wax and hexane extracts from Citrus spp. peels. Mem Inst Oswaldo 102:681–685
  • Kulkarni, T.R., Mateenuddin, M., Bodhankar S.L. and Saharabudhe, R.A. (2012) Reversible anti-fertility effect of lemon seeds (Citrus limonum) in male albino rats. Int J Res Pharm Biomed Sci 3:545–550
  • Laemmli, U.K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680–685
  • Lohiya, N.K., Manivannan, B., Mishra, P.K. and Pathak, N. (2001) Prospects of developing a plant based male contraceptive pill. In Current Status in Fertility Regulation: Indigenous and Modern Approaches. Chowdhury S.R., Gupta, C.M. and Kamboj, V.P., eds. Lucknow: Central Drug Research Institute, pp. 99–119
  • Lowry, O.H., Rosebrough, N.J., Farr, A.L. and Randall, R.J. (1951) Protein measurement with the folin phenol reagent. J Biol Chem 193:265–275
  • Meerwal, P. and Jain, G.C. (2015) Male fertility regulation with plant products: a review. IJPCBS 5:146–162
  • Mishra, R.K. and Singh, S.K. (2005) Effect of aqueous leaf extract of Azadirachta indica on the reproductive organs in male mice. Indian J Exp Biol 43:1093–1103
  • Mishra, R.K. and Singh, S.K. (2008) Safety assessment of Syzygium aromaticum flower bud (clove) extract with respect to testicular function in mice. Food Chem Toxicol 46:3333–3338
  • Mishra, R.K. and Singh, S.K. (2009) Reversible antifertility effect of aqueous rhizome extract of Curcuma longa L. in male laboratory mice. Contraception 79:479–487
  • Ogbuewu, I.P., Unamba-Oparah, I.C., Odoemenam, V.U., Etuk, I.F. and Okoli, I.C. (2011) The potentiality of medicinal plants as the source of new contraceptive principles in males. N Am J Med Sci 3:255–263
  • O’Donell, L., Meachem, S.J., Stanton, P.G. and McLachlan, R.I. (2006) Endocrine regulation of spermatogenesis. In Knobil and Neill’s Physiology of Reproduction. Neill, J.D., ed. St Louis MO: Elsevier Academic Press, pp. 1017–1069
  • Porter, A.G. and Jänicke, R.U. (1999) Emerging roles of caspase-3 in apoptosis. Cell Death Differ 6:99–104
  • Rajalakshmi, M. (1992) Regulation of male fertility: Epididymis as a potential extragonadal site. In Frontiers in Reproductive Physiology. Ghosh, D. and Sengupta, J., eds New Delhi: Wiley Eastern Ltd., pp. 63–66
  • Reitman, S. and Frankel, S. (1957) A colorimetric method for the determination of serum glutamate oxaloacetate and glutamic pyruvic transaminases. Amer J Clin Pathol 28:56–63
  • Russell, L.D., Ettlin, R.A., Hikim, A.P.S. and Clegg, E.D. (1990) Histological and histopathological evaluation of the testis. Cache River Press; Clearwater, FL
  • Russell, L.D., Vogl, A.W. and Weber, J.E. (1987) Actin localization in male germ cell intercellular bridges and the disruption of selected bridges by cytochalasin D. Am J Anat 180:25–40
  • Singh, A. and Singh, S.K. (2008) Reversible antifertility effect of aqueous leaf extract of Allamanda cathartica L. in male laboratory mice. Andrologia 40:337–345
  • Singh, A. and Singh, S.K. (2009) Evaluation of antifertility potential of Brahmi in male mouse. Contraception 79:71–79
  • Singh, S.K. and Abe, K. (1987) Light and electron microscopic observations of giant cells in the mouse testis after efferent duct ligation. Arch Histol Jpn 50:579–585
  • Singh, S.K. and Chakravarty, S. (2003) Antispermatogenic and antifertility effects of 20, 25-diazacholesterol dihydrochloride in mice. Reprod Toxicol 17:37–44
  • Singh, S.K. and Rath, S.K. (1990) Histologic changes in the mouse testis after treatment with gossypol tetra-acetic acid. Arch Histol Cytol 53:393–396
  • Stocco, D. and McPhaul, M. (2006) Physiology of testicular steroidogenesis. In Knobil and Neill’s Physiology of Reproduction. Neill, J.D., ed. St Louis, MO: Elsevier Academic Press, pp. 977–1016
  • Talalay, P. (1962) Hydroxysteroid dehydrogenase. In: Methods in Enzymology. Colowick, S.P. and Kaplan, N.O, eds. New York: Academic Press, pp 512–516
  • Travison, T.G., Morley, J.E., Araujo, A.B., O’Donnell, A.B. and McKinlay, J.B. (2006) The relationship between libido and testosterone levels in aging men. J Clin Endocrinol Metab 91:2509–2513
  • Verma, H.P. and Singh, S.K. (2014) Effect of aqueous leaf extract of dalbergia sissoo Roxb. on spermatogenesis and fertility in male mice. Eur J Contracept Reprod Health Care 19:475–486
  • WHO (1986) WHO Chemical Guidelines, CG-03, 1001A/ip. World Health Organization; Geneva .
  • WHO (1999) World Health Organization laboratory manual for the examination of human semen and semen-cervical mucus interaction. University Press Cambridge; Cambridge .

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