Advanced search
Publication Cover
Journal of Plastic Surgery and Hand Surgery Volume 50, 2016 - Issue 3
Journal homepage
461
Views
13
CrossRef citations to date
0
Altmetric
Research Article (Experimental)

Characterisation of the inflammatory response in Dupuytren’s disease

Christina MayerlLaboratory of Autoimmunity, Division of Experimental Pathophysiology and Immunology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria, ;Department of Internal Medicine III – Cardiology and Angiology, Medical University of Innsbruck, Innsbruck, Austria,
,
Barbara Del FrariDepartment of Plastic, Reconstructive and Aesthetic Surgery, Medical University of Innsbruck, Innsbruck, Austria, and
,
Walther ParsonInstitute of Legal Medicine, Medical University of Innsbruck, Innsbruck, Austria
,
Guenther BoeckLaboratory of Autoimmunity, Division of Experimental Pathophysiology and Immunology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria,
,
Hildegunde Piza-KatzerDepartment of Plastic, Reconstructive and Aesthetic Surgery, Medical University of Innsbruck, Innsbruck, Austria, and
,
Georg WickLaboratory of Autoimmunity, Division of Experimental Pathophysiology and Immunology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria,
&
Dolores WolframDepartment of Plastic, Reconstructive and Aesthetic Surgery, Medical University of Innsbruck, Innsbruck, Austria, and Correspondence[email protected]
 show all
Pages 171-179 | Received 10 Aug 2015, Accepted 28 Oct 2015, Published online: 06 Feb 2016

References

  • Wilbrand S, Flodmark C, Ekbom A, Gerdin B. Activation markers of connective tissue in Dupuytren's contracture: relation to postoperative outcome. . Scand J Plast Reconstr Surg Hand Surg 2003;37:283–92.
  • Mickelson DT, Noland SS, Watt AJ, et al. Prospective randomized controlled trial comparing 1- versus 7-day manipulation following collagenase injection for Dupuytren contracture. J Hand Surg Am 2014;39:1933–41.
  • Shih B, Bayat A. Scientific understanding and clinical management of Dupuytren disease. Nat Rev Rheumatology 2010;6:715–26.
  • Dolmans GH, Werker PM, Hennies HC, et al. Wnt Signaling and Dupuytren's disease. N Engl J Med 2011;365:307–17.
  • Kischer CW, Speer DP. Microvascular changes in Dupuytren's contracture. J Hand Surg Am 1984;9A:58–62.
  • Burke FD, Proud G, Lawson IJ, et al. An assessment of the effects of exposure to vibration, smoking, alcohol and diabetes on the prevalence of Dupuytren's disease in 97,537 miners. J Hand Surg Eur 2007;32:400–6.
  • Murrell GAC, Francis M, Bromley L. Free radicals and Dupuytren's contracture. Br Med J 1987;295:1373–5.
  • Wick G, Backovic A, Rabensteiner E, et al. The immunology of fibrosis: innate and adaptive responses. Trends Immunol 2010;31:110–19.
  • Wick G, Grundtman C, Mayerl C, et al. The immunology of fibrosis. Annu Rev Immunol 2013;31:107–35.
  • Andrew JG, Andrew SM, Ash A, Turner B. An investigation into the role of inflammatory cells in Dupuytren's disease. J Hand Surg Br 1991;16:237–9.
  • Gudmundsson KG, Arngrímsson R, Arinbjarnarson S. Tand B-lymphocyte subsets in patients with Dupuytren's disease. Correlations with disease severity. J Hand Surg Br 1998;23:724–7.
  • Baird KS, Alwan WH, Crossan JF, Wojciak B. Tcell-mediated response in Dupuytren's disease. Lancet 1993;342:366
  • Wolfram D, Rabensteiner E, Grundtman C, et al. T regulatory cells and TH17 cells in peri-silicone implant capsular fibrosis. Plast Reconstr Surg 2012;129:327e–37.
  • Rehman S, Salway F, Stanley JK, et al. Molecular phenotypic descriptors of Dupuytren's disease defined using informatics analysis of the transcriptome. J Hand Surg Am 2008;33:359–72.
  • Herndler-Brandstetter D, Schwaiger S, Veel E, et al. CD25-expressing CD8+ T cells are potent memory cells in old age. J Immunol 2005;175:1566–74.
  • Lee LC, Zhang AY, Chong AK, et al. Expression of a novel gene, MafB, in Dupuytren's disease. J Hand Surg 2006;31A:211–18.
  • Meek RM, McLellan S, Crossan JF. Dupuytren's disease. A model for the mechanism of fibrosis and its modulation by steroids. J Bone Joint Surg Br. 1999;81(4):732–8. Erratum in: J Bone Joint Surg Br 1999;81(5):938.
  • Qureshi FI, Hornigold R, Spencer JD, Hall SM. Langerhans cells in Dupuytren's contracture. J Hand Surg Br 2001;26:362–7.
  • Ma F, Li Y, Jia L, et al. Macrophage-stimulated cardiac fibroblast production of IL-6 is essential for TGF β/Smad activation and cardiac fibrosis induced by angiotensin II. PLoS One 2009;7:e35144.
  • O'Reilly S, Ciechomska M, Cant R, van Laar JM. Interleukin-6 (IL-6) trans signaling drives a STAT3-dependent pathway that leads to hyperactive transforming growth factor-β (TGF-β) signaling promoting SMAD3 activation and fibrosis via Gremlin protein. J Biol Chem 2014;289:9952–60.
  • Boehm U, Klamp T, Groot M, Howard JC. Cellular responses to interferon-gamma. Annu Rev Immunol 1997;15:749–95.
  • Wick G, Knoflach M, Xu Q. Autoimmune and inflammatory mechanisms in atherosclerosis. Annu Rev Immunol 2004;22:361–403.
  • Kraljevic Pavelic S, Sedic M, Hock K, et al. An integrated proteomics approach for studying the molecular pathogenesis of Dupuytren's disease. J Pathol 2009;217:524–33.
  • Brandes G, Reale E, Messina A. Microfilament system in the microvascular endothelium of the palmar fascia affected by mechanical stress applied from outside. Virchows Arch 1996;429:165–72.
  • Murrell GA, Francis MJ, Bromley L. Modulation of fibroblast proliferation by oxygen free radicals. Biochem J 1990;265:659–65.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.